Motif ID: GLI1..3.p2

Z-value: 1.543


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI1chr12_+_578539170.561.3e-19Click!
GLI2chr2_+_1215548660.473.3e-13Click!
GLI3chr7_-_422766170.433.9e-11Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_175792444 27.877 NM_173664
 ARL10
ADP-ribosylation factor-like 10
chr12_-_6798419 25.557 ZNF384
zinc finger protein 384
chr12_-_6798619 23.914 NM_001039920
NM_001135734
 ZNF384

zinc finger protein 384

chr22_-_19512001 23.526 CLDN5
claudin 5
chr22_-_19511777 20.579 CLDN5
claudin 5
chr22_+_22569155 20.551


chrX_-_106960028 19.076 TSC22D3
TSC22 domain family, member 3
chrX_-_78622711 18.708 ITM2A
integral membrane protein 2A
chr8_+_21916858 17.748 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr16_+_28834407 17.571 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
 ATXN2L




ataxin 2-like




chr8_+_21916685 17.521 NM_001114138
NM_001978
 EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr12_-_6798528 17.113 NM_133476
 ZNF384
zinc finger protein 384
chr15_-_77712436 16.665 NM_024776
 PEAK1
NKF3 kinase family member
chr11_-_72380107 16.206 NM_001146209
 PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr10_+_104503724 15.532 NM_001083913
 C10orf26
chromosome 10 open reading frame 26
chr16_+_28834565 15.386 ATXN2L
ataxin 2-like
chr12_-_45269953 14.662 NELL2
NEL-like 2 (chicken)
chr9_-_113800243 14.205 NM_001401
NM_057159
 LPAR1

lysophosphatidic acid receptor 1

chrX_+_13671224 14.070 NM_152634
 TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr3_-_10067989 13.933 CIDECP
cell death-inducing DFFA-like effector c pseudogene

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 126 entries
enrichment   p-value GO term description
2.53 2.33e-02 GO:0045637 regulation of myeloid cell differentiation
2.15 6.83e-03 GO:0040017 positive regulation of locomotion
2.14 1.73e-04 GO:0043193 positive regulation of gene-specific transcription
2.11 1.98e-02 GO:0030335 positive regulation of cell migration
2.11 1.98e-02 GO:2000147 positive regulation of cell motility
2.10 1.37e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
2.09 1.62e-02 GO:0051272 positive regulation of cellular component movement
1.94 5.52e-05 GO:0045597 positive regulation of cell differentiation
1.91 9.18e-04 GO:0051270 regulation of cellular component movement
1.90 2.42e-06 GO:0032583 regulation of gene-specific transcription
1.89 1.81e-03 GO:0040012 regulation of locomotion
1.88 7.37e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.88 6.75e-03 GO:0030334 regulation of cell migration
1.87 9.97e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.86 1.01e-02 GO:2000145 regulation of cell motility
1.84 1.21e-03 GO:0007411 axon guidance
1.79 2.27e-04 GO:0007409 axonogenesis
1.78 1.01e-04 GO:0051094 positive regulation of developmental process
1.77 8.48e-08 GO:0010628 positive regulation of gene expression
1.76 1.03e-06 GO:0045893 positive regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.61 1.19e-02 GO:0009986 cell surface
1.44 6.51e-05 GO:0000267 cell fraction
1.43 3.60e-03 GO:0005626 insoluble fraction
1.43 4.36e-03 GO:0005624 membrane fraction
1.41 7.35e-05 GO:0005887 integral to plasma membrane
1.40 1.21e-04 GO:0031226 intrinsic to plasma membrane
1.37 6.98e-08 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.96 6.02e-06 GO:0016563 transcription activator activity
1.94 1.74e-04 GO:0032403 protein complex binding
1.92 8.16e-03 GO:0010843 promoter binding
1.89 1.09e-02 GO:0000975 regulatory region DNA binding
1.89 1.09e-02 GO:0001067 regulatory region nucleic acid binding
1.89 1.09e-02 GO:0044212 transcription regulatory region DNA binding
1.85 4.63e-04 GO:0008134 transcription factor binding
1.76 1.26e-02 GO:0005261 cation channel activity
1.74 2.98e-08 GO:0043565 sequence-specific DNA binding
1.74 8.10e-03 GO:0005083 small GTPase regulator activity
1.58 1.27e-07 GO:0001071 nucleic acid binding transcription factor activity
1.58 1.27e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 5.28e-07 GO:0030528 transcription regulator activity
1.55 2.24e-02 GO:0030695 GTPase regulator activity
1.53 3.47e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.42 8.42e-04 GO:0005102 receptor binding
1.36 4.55e-02 GO:0030234 enzyme regulator activity
1.26 1.57e-03 GO:0003677 DNA binding
1.19 4.85e-12 GO:0005515 protein binding
1.11 2.23e-12 GO:0005488 binding