Motif ID: GTF2A1,2.p2

Z-value: 2.182


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2A2chr15_-_59949536-0.768.3e-43Click!
GTF2A1chr14_-_816875740.627.3e-25Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_33182689 61.781 NM_001105570
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr11_-_111782447 45.610 NM_001885
CRYAB
crystallin, alpha B
chr18_-_74728963 41.003 MBP
myelin basic protein
chr18_-_74729049 40.254 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr9_+_139872014 31.784 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr1_-_57888785 29.541 DAB1
disabled homolog 1 (Drosophila)
chr19_-_57336373 28.951 NM_001146186
PEG3
paternally expressed 3
chr1_-_57044980 27.688 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_57045214 26.902 PPAP2B
phosphatidic acid phosphatase type 2B
chr20_+_36149606 26.015 NM_005386
NM_181689
NNAT

neuronatin

chr1_-_57045129 25.888 PPAP2B
phosphatidic acid phosphatase type 2B
chr13_-_45150601 25.214 NM_001243799
NM_183422
TSC22D1

TSC22 domain family, member 1

chr1_+_152635871 24.591 NM_178430
LCE2D
late cornified envelope 2D
chr1_-_57045235 24.442 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr6_-_46293628 23.795 NM_005822
RCAN2
regulator of calcineurin 2
chr16_+_22825806 23.457 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr16_+_22825481 22.097 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr20_-_44455932 22.018 NM_003279
TNNC2
troponin C type 2 (fast)
chr12_+_109577201 21.940 NM_001093
ACACB
acetyl-CoA carboxylase beta
chr17_+_1665233 21.183 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_-_7245048 21.100 C1R
complement component 1, r subcomponent
chr19_+_39833096 20.866 SAMD4B
sterile alpha motif domain containing 4B
chr16_+_58283819 20.505 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr22_+_22735134 20.461 CYAT1
immunoglobulin lambda light chain-like
chr7_+_99699129 20.201 NM_004722
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr9_+_35538890 20.138 RUSC2
RUN and SH3 domain containing 2
chr2_-_237172987 19.738 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr17_+_1665342 19.477 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_-_15038724 18.971 NM_000900
NM_001190839
MGP

matrix Gla protein

chr7_+_97910978 18.924 NM_001159491
NM_015379
BRI3

brain protein I3

chr22_+_22735207 18.901 IGLJ3
immunoglobulin lambda joining 3
chr22_+_22735202 18.686


chr12_+_53491417 18.552 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr2_+_27301434 18.448 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr19_+_39833132 18.348 SAMD4B
sterile alpha motif domain containing 4B
chr2_+_66662516 18.254 NM_002398
MEIS1
Meis homeobox 1
chr12_-_7245006 18.252 NM_001733
C1R
complement component 1, r subcomponent
chr6_-_46293404 18.243 RCAN2
regulator of calcineurin 2
chr2_+_27301693 18.029 EMILIN1
elastin microfibril interfacer 1
chr6_+_43139190 17.972 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr11_-_5248180 17.902 NM_000518
HBB
hemoglobin, beta
chr19_-_45909566 17.799 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr12_+_53491448 17.232 IGFBP6
insulin-like growth factor binding protein 6
chr6_+_43139201 17.008 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr19_+_39833099 16.901 NM_018028
SAMD4B
sterile alpha motif domain containing 4B
chr19_-_46389307 16.885 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr3_+_133464883 16.812 NM_001063
TF
transferrin
chr11_-_62457001 16.703 LRRN4CL
LRRN4 C-terminal like
chr14_-_73360792 16.672 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr22_+_22676814 16.641


chr22_+_31031672 16.611 NM_001001479
SLC35E4
solute carrier family 35, member E4
chr1_-_20306908 16.528 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr17_+_41006094 16.520 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr7_+_29234325 16.351 CHN2
chimerin (chimaerin) 2
chr11_-_62457370 16.285 NM_203422
LRRN4CL
LRRN4 C-terminal like
chr19_-_49140569 15.994 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr9_+_35538628 15.977 NM_001135999
RUSC2
RUN and SH3 domain containing 2
chr17_-_73893016 15.921 NM_173547
TRIM65
tripartite motif containing 65
chr17_+_42219382 15.715 C17orf53
chromosome 17 open reading frame 53
chr1_+_203274646 15.655 NM_006763
BTG2
BTG family, member 2
chr22_+_22758538 15.551


chr15_-_73661141 15.528 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr14_+_75745480 15.084 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_+_31783314 14.948 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr17_+_42219300 14.828 C17orf53
chromosome 17 open reading frame 53
chr3_+_50304989 14.680 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr1_+_163038934 14.674 NM_001113381
RGS4
regulator of G-protein signaling 4
chr1_-_11714396 14.658 FBXO2
F-box protein 2
chr17_-_26697293 14.417 VTN
vitronectin
chr22_+_29876180 14.304 NM_021076
NEFH
neurofilament, heavy polypeptide
chr17_+_74733468 14.237 NM_001242532
NM_001242533
NM_001242535
NM_001242536
NM_001242537
NM_024311
MFSD11





major facilitator superfamily domain containing 11





chr13_-_45150391 14.182 TSC22D1
TSC22 domain family, member 1
chr5_-_149792276 14.160 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr11_+_64692052 14.130 NM_006244
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr13_+_111855406 13.967 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr19_-_50316360 13.965 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr19_+_40697516 13.696 NM_002446
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr1_-_151319674 13.649 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr19_+_840970 13.596 NM_002777
PRTN3
proteinase 3
chr1_+_209859524 13.592 NM_001206741
NM_181755
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr7_-_137028275 13.480 PTN
pleiotrophin
chr3_-_48130283 13.468 MAP4
microtubule-associated protein 4
chr17_+_1665306 13.368 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_+_168148215 13.262 TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr17_+_17206626 13.218 NM_020201
NT5M
5',3'-nucleotidase, mitochondrial
chrX_-_3264680 13.198 NM_015419
MXRA5
matrix-remodelling associated 5
chr11_+_13299260 13.140 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr1_+_100818031 13.136 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr11_-_5255712 13.090 NM_000519
HBD
hemoglobin, delta
chr11_+_13299376 13.004 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr5_-_149792370 12.992 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr9_+_87284625 12.962 NM_001007097
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr22_-_41032684 12.885 NM_020831
MKL1
megakaryoblastic leukemia (translocation) 1
chr3_-_4508939 12.873 SUMF1
sulfatase modifying factor 1
chr1_+_159173802 12.855 NM_002036
DARC
Duffy blood group, chemokine receptor
chr11_+_63993720 12.810 NM_001128612
NM_001128613
NM_032344
NUDT22


nudix (nucleoside diphosphate linked moiety X)-type motif 22


chr1_+_53192021 12.804 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr15_-_83378488 12.800 NM_004644
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr2_+_99757947 12.786 NM_144706
C2orf15
chromosome 2 open reading frame 15
chr15_-_55611289 12.784


chr10_-_45474210 12.777 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr8_+_42128821 12.757 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr11_+_13299372 12.729 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chrX_+_50653734 12.668 NM_005448
BMP15
bone morphogenetic protein 15
chr6_-_167797917 12.665 NM_004610
TCP10
t-complex 10 homolog (mouse)
chr20_+_47895168 12.500 ZNFX1-AS1
ZNFX1 antisense RNA 1 (non-protein coding)
chr3_+_133494275 12.440 TF
transferrin
chr6_-_24583454 12.427 NM_001252328
KIAA0319
KIAA0319
chr4_-_47983430 12.426 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_+_163038564 12.364 NM_005613
RGS4
regulator of G-protein signaling 4
chr13_+_28712379 12.296 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr9_-_35732089 12.201 TLN1
talin 1
chr1_-_207119707 12.196 NM_002644
PIGR
polymeric immunoglobulin receptor
chr8_-_145701717 12.153 NM_003923
FOXH1
forkhead box H1
chr1_+_244998592 12.136 NM_198076
FAM36A
family with sequence similarity 36, member A
chr10_+_17794250 12.115 NM_001098844
TMEM236
transmembrane protein 236
chr22_-_18923654 12.105 PRODH
proline dehydrogenase (oxidase) 1
chr1_-_153013593 12.073 NM_006945
SPRR2D
small proline-rich protein 2D
chrX_-_48858617 12.062 NM_020137
NM_207672
GRIPAP1

GRIP1 associated protein 1

chr19_-_13617037 12.030 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr1_+_164818083 11.980 PBX1
pre-B-cell leukemia homeobox 1
chr1_-_20306093 11.964 NM_001161729
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr9_+_124043719 11.938 GSN
gelsolin
chr8_+_42128834 11.913 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr5_+_150020201 11.904 NM_001109974
NM_007286
SYNPO

synaptopodin

chr12_+_11802905 11.869 ETV6
ets variant 6
chr14_+_93389491 11.848 CHGA
chromogranin A (parathyroid secretory protein 1)
chr16_+_83986826 11.805 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr3_+_50242688 11.785 NM_006841
SLC38A3
solute carrier family 38, member 3
chr22_+_30792929 11.774 NM_001204204
NM_012429
NM_033382
SEC14L2


SEC14-like 2 (S. cerevisiae)


chr2_+_74120132 11.759 ACTG2
actin, gamma 2, smooth muscle, enteric
chr11_-_73720281 11.683 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr12_+_11802642 11.648 ETV6
ets variant 6
chr12_-_11324129 11.584 PRH1-PRR4
TAS2R14
PRH1
PRH1-PRR4 readthrough
taste receptor, type 2, member 14
proline-rich protein HaeIII subfamily 1
chr22_+_22786283 11.582


chr20_-_47894591 11.546 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr19_+_5904842 11.238 NM_001017921
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr8_-_23315135 11.211 ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chrX_-_106960268 11.198 NM_004089
TSC22D3
TSC22 domain family, member 3
chr12_+_14927305 11.155 H2AFJ
H2A histone family, member J
chr15_+_32933869 11.155 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr17_+_40610897 11.132 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_+_150230168 11.100 NM_012113
CA14
carbonic anhydrase XIV
chr17_+_42219235 11.092 NM_001171251
NM_024032
C17orf53

chromosome 17 open reading frame 53

chr17_+_74553845 11.089 LOC100507246
uncharacterized LOC100507246
chr10_+_7745325 11.082 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr17_+_40610875 11.029 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr10_+_7745284 10.946 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_+_41086189 10.908 NM_001843
NM_175038
CNTN1

contactin 1

chrX_-_139866582 10.867 NM_004065
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr10_+_7745229 10.850 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr20_+_44657858 10.764 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr22_-_41032623 10.761 MKL1
megakaryoblastic leukemia (translocation) 1
chr2_+_66662692 10.695 MEIS1
Meis homeobox 1
chr22_-_32589386 10.686 NM_006605
RFPL2
ret finger protein-like 2
chr1_+_100818052 10.626 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr3_-_62359189 10.617 NM_018008
FEZF2
FEZ family zinc finger 2
chr3_-_170303774 10.559 NM_020949
SLC7A14
solute carrier family 7 (orphan transporter), member 14
chr12_+_81110689 10.554 NM_005593
MYF5
myogenic factor 5
chr11_-_117166247 10.508 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr5_+_40909617 10.504 C7
complement component 7
chr12_-_49504337 10.454 LMBR1L
limb region 1 homolog (mouse)-like
chr1_+_107683548 10.451 NTNG1
netrin G1
chr2_+_74120092 10.438 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr17_-_26697310 10.356 VTN
vitronectin
chr3_+_42190825 10.354 TRAK1
trafficking protein, kinesin binding 1
chr12_-_52715140 10.352 NM_002282
KRT83
keratin 83
chr22_+_33196801 10.303 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr22_-_29784430 10.170 AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr12_-_54582588 10.146 NM_001243789
NM_001243790
NM_001243787
NM_001243788
NM_001243791
NM_014311
SMUG1





single-strand-selective monofunctional uracil-DNA glycosylase 1





chr22_+_38004676 10.124 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr20_+_44657812 10.102 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr22_-_29784568 10.100 NM_001127
NM_001166019
NM_145730
AP1B1


adaptor-related protein complex 1, beta 1 subunit


chr8_-_134309448 10.097 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr1_+_100818007 10.070 NM_003672
NM_033312
NM_033313
CDC14A


CDC14 cell division cycle 14 homolog A (S. cerevisiae)


chr15_-_64648359 10.064 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr19_-_49176263 10.044 NM_145807
NTN5
netrin 5
chr1_-_145075636 10.031 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_156399183 10.027 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr17_+_61554420 10.016 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr2_+_28615771 9.991 NM_005253
FOSL2
FOS-like antigen 2
chr8_+_19796581 9.955 NM_000237
LPL
lipoprotein lipase
chr15_-_73661604 9.954 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr17_+_40610857 9.913 NM_001130020
NM_001130021
NM_005177
ATP6V0A1


ATPase, H+ transporting, lysosomal V0 subunit a1


chr19_-_12662191 9.907 NM_144976
ZNF564
zinc finger protein 564
chr18_-_21017816 9.906 NM_032933
TMEM241
transmembrane protein 241
chr1_+_11866240 9.891 CLCN6
chloride channel 6
chr17_-_26697224 9.863 VTN
vitronectin
chr6_+_106546736 9.832 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr11_-_70507836 9.831 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr17_-_66951381 9.818 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr14_+_23563888 9.787 C14orf119
chromosome 14 open reading frame 119
chr12_-_49504612 9.746 LMBR1L
limb region 1 homolog (mouse)-like
chr22_+_23229959 9.732 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chrX_+_16141423 9.725 NM_005314
GRPR
gastrin-releasing peptide receptor
chr11_-_1593149 9.670 NM_004420
DUSP8
dual specificity phosphatase 8
chr3_-_48130633 9.657 NM_001134364
NM_002375
NM_030885
MAP4


microtubule-associated protein 4


chr15_+_59908908 9.622 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr15_-_74659926 9.519 NM_000781
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr15_-_64648214 9.507 CSNK1G1
casein kinase 1, gamma 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 4.22e-14 GO:0065007 biological regulation
1.14 2.45e-12 GO:0009987 cellular process
1.40 4.19e-12 GO:0023052 signaling
1.29 3.81e-10 GO:0032501 multicellular organismal process
1.41 7.54e-10 GO:0048856 anatomical structure development
1.43 2.22e-09 GO:0048731 system development
1.21 2.42e-09 GO:0050789 regulation of biological process
1.24 5.95e-09 GO:0050896 response to stimulus
1.33 6.67e-09 GO:0051716 cellular response to stimulus
1.33 5.89e-08 GO:0032502 developmental process
1.21 7.30e-08 GO:0050794 regulation of cellular process
1.77 1.00e-07 GO:0009611 response to wounding
1.35 1.39e-07 GO:0007165 signal transduction
1.85 1.48e-07 GO:0007267 cell-cell signaling
1.34 2.57e-07 GO:0007275 multicellular organismal development
1.70 4.95e-07 GO:0007154 cell communication
1.55 9.03e-07 GO:0007399 nervous system development
1.43 3.25e-06 GO:0065008 regulation of biological quality
1.40 7.41e-06 GO:0042221 response to chemical stimulus
1.68 3.23e-05 GO:0040011 locomotion
1.39 1.02e-04 GO:0048869 cellular developmental process
1.59 1.29e-04 GO:0009605 response to external stimulus
1.38 2.15e-04 GO:0030154 cell differentiation
1.34 2.63e-04 GO:0006950 response to stress
2.13 4.27e-04 GO:0006954 inflammatory response
1.44 9.10e-04 GO:0009653 anatomical structure morphogenesis
1.62 1.72e-03 GO:0007155 cell adhesion
1.62 1.72e-03 GO:0022610 biological adhesion
1.46 1.88e-03 GO:0051239 regulation of multicellular organismal process
1.46 3.85e-03 GO:0002376 immune system process
1.52 1.14e-02 GO:0006811 ion transport
4.44 1.40e-02 GO:0044259 multicellular organismal macromolecule metabolic process
1.57 1.43e-02 GO:0006955 immune response
1.33 1.72e-02 GO:0048583 regulation of response to stimulus
1.95 1.73e-02 GO:0001944 vasculature development
1.33 1.74e-02 GO:0048513 organ development
1.64 1.82e-02 GO:0042060 wound healing
1.53 1.85e-02 GO:0006952 defense response
1.34 1.89e-02 GO:0007166 cell surface receptor linked signaling pathway
1.66 2.05e-02 GO:0006928 cellular component movement
2.20 2.48e-02 GO:0003012 muscle system process
1.96 2.78e-02 GO:0001568 blood vessel development
1.64 2.99e-02 GO:0050878 regulation of body fluid levels
1.49 3.13e-02 GO:0022008 neurogenesis
4.37 4.29e-02 GO:0032963 collagen metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.92 1.09e-14 GO:0044421 extracellular region part
1.60 5.66e-14 GO:0005576 extracellular region
1.54 2.62e-12 GO:0044459 plasma membrane part
1.88 5.16e-10 GO:0005615 extracellular space
1.65 3.90e-09 GO:0005887 integral to plasma membrane
1.63 1.01e-08 GO:0031226 intrinsic to plasma membrane
2.06 2.64e-06 GO:0031012 extracellular matrix
1.23 6.40e-05 GO:0005886 plasma membrane
1.23 1.00e-04 GO:0071944 cell periphery
2.00 1.75e-04 GO:0005578 proteinaceous extracellular matrix
1.56 2.55e-04 GO:0042995 cell projection
1.77 2.43e-03 GO:0044463 cell projection part
3.42 2.91e-03 GO:0031983 vesicle lumen
1.74 5.40e-03 GO:0043005 neuron projection
1.57 1.16e-02 GO:0030054 cell junction
3.31 1.62e-02 GO:0031093 platelet alpha granule lumen
2.36 2.08e-02 GO:0044420 extracellular matrix part
3.24 2.09e-02 GO:0034774 secretory granule lumen
3.11 3.43e-02 GO:0044309 neuron spine
3.11 3.43e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
1.37 4.09e-02 GO:0000267 cell fraction
2.92 4.23e-02 GO:0031091 platelet alpha granule

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.60 1.03e-05 GO:0005102 receptor binding
1.13 2.71e-03 GO:0005515 protein binding
1.07 3.23e-03 GO:0005488 binding
2.78 1.39e-02 GO:0005201 extracellular matrix structural constituent
2.06 1.53e-02 GO:0005125 cytokine activity
1.45 1.56e-02 GO:0022857 transmembrane transporter activity
2.10 1.75e-02 GO:0005126 cytokine receptor binding
3.27 1.94e-02 GO:0042379 chemokine receptor binding
1.38 2.62e-02 GO:0005215 transporter activity
1.41 4.38e-02 GO:0001071 nucleic acid binding transcription factor activity
1.41 4.38e-02 GO:0003700 sequence-specific DNA binding transcription factor activity