Motif ID: GTF2I.p2

Z-value: 2.613


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2Ichr7_+_74072038-0.111.2e-01Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_29600668 56.935 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_30934437 56.364 FBXL19-AS1
FBXL19 antisense RNA 1 (non-protein coding)
chr1_-_20812727 54.164 NM_018584
 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_-_49149252 51.608 NM_001217
 CA11
carbonic anhydrase XI
chr12_-_6798419 46.792 ZNF384
zinc finger protein 384
chr4_-_16900348 44.774 NM_001130834
NM_001290
 LDB2

LIM domain binding 2

chr12_-_45270071 43.402 NELL2
NEL-like 2 (chicken)
chr12_-_45270157 43.216 NM_001145108
NM_006159
 NELL2

NEL-like 2 (chicken)

chr4_-_16900256 41.959 LDB2
LIM domain binding 2
chr6_-_29600859 39.931 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr12_+_6930689 39.041 NM_014449
NM_019858
 GPR162

G protein-coupled receptor 162

chr11_+_17757494 38.466 NM_001112741
NM_004976
 KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr4_-_16900028 37.724 LDB2
LIM domain binding 2
chr6_-_29600959 36.800 NM_001470
NM_021904
 GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr12_-_45269953 34.878 NELL2
NEL-like 2 (chicken)
chr7_+_64498643 33.959 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr3_-_42307661 33.776 NM_000729
 CCK
cholecystokinin
chr12_-_45270632 32.683 NM_001145107
 NELL2
NEL-like 2 (chicken)
chr4_-_5890142 31.750 CRMP1
collapsin response mediator protein 1
chr5_+_17217474 31.715 NM_006317
 BASP1
brain abundant, membrane attached signal protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 358 entries
enrichment   p-value GO term description
3.93 2.29e-02 GO:0071548 response to dexamethasone stimulus
3.03 2.72e-03 GO:0003156 regulation of organ formation
3.02 2.94e-04 GO:0031128 developmental induction
3.02 2.94e-04 GO:0045168 cell-cell signaling involved in cell fate commitment
2.99 8.30e-03 GO:0060603 mammary gland duct morphogenesis
2.90 7.93e-03 GO:0050807 regulation of synapse organization
2.79 7.19e-04 GO:0060443 mammary gland morphogenesis
2.76 6.45e-03 GO:0050803 regulation of synapse structure and activity
2.73 1.99e-04 GO:0061180 mammary gland epithelium development
2.62 4.10e-02 GO:0043535 regulation of blood vessel endothelial cell migration
2.58 1.05e-02 GO:0002088 lens development in camera-type eye
2.57 3.36e-02 GO:0061035 regulation of cartilage development
2.47 1.74e-02 GO:0071363 cellular response to growth factor stimulus
2.42 8.71e-04 GO:0001649 osteoblast differentiation
2.39 5.37e-04 GO:0070848 response to growth factor stimulus
2.32 1.22e-02 GO:0009880 embryonic pattern specification
2.32 1.22e-02 GO:0048663 neuron fate commitment
2.32 1.22e-02 GO:0060021 palate development
2.30 2.32e-05 GO:0048638 regulation of developmental growth
2.24 7.26e-05 GO:0022612 gland morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 57 entries
enrichment   p-value GO term description
2.57 4.62e-03 GO:0034704 calcium channel complex
2.44 1.89e-03 GO:0042734 presynaptic membrane
2.12 7.89e-05 GO:0033267 axon part
1.94 4.80e-09 GO:0030424 axon
1.94 3.00e-03 GO:0014069 postsynaptic density
1.92 2.84e-06 GO:0034703 cation channel complex
1.90 2.72e-03 GO:0008076 voltage-gated potassium channel complex
1.90 2.72e-03 GO:0034705 potassium channel complex
1.90 4.48e-02 GO:0030426 growth cone
1.90 4.48e-02 GO:0031256 leading edge membrane
1.87 2.53e-07 GO:0043025 neuronal cell body
1.86 2.05e-07 GO:0044297 cell body
1.85 3.00e-17 GO:0043005 neuron projection
1.84 1.42e-07 GO:0030425 dendrite
1.78 9.19e-03 GO:0019717 synaptosome
1.76 4.33e-14 GO:0045202 synapse
1.74 2.16e-06 GO:0034702 ion channel complex
1.73 2.97e-09 GO:0044456 synapse part
1.72 5.73e-04 GO:0045211 postsynaptic membrane
1.56 1.02e-03 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

Showing 1 to 20 of 64 entries
enrichment   p-value GO term description
2.87 6.63e-04 GO:0005245 voltage-gated calcium channel activity
2.54 5.70e-06 GO:0003707 steroid hormone receptor activity
2.52 2.30e-02 GO:0017046 peptide hormone binding
2.47 9.45e-06 GO:0004879 ligand-dependent nuclear receptor activity
2.06 6.06e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.04 4.57e-04 GO:0019199 transmembrane receptor protein kinase activity
1.99 2.56e-03 GO:0005262 calcium channel activity
1.96 4.01e-07 GO:0022843 voltage-gated cation channel activity
1.88 1.36e-03 GO:0005057 receptor signaling protein activity
1.83 2.03e-02 GO:0008081 phosphoric diester hydrolase activity
1.80 1.28e-02 GO:0005249 voltage-gated potassium channel activity
1.79 4.00e-04 GO:0004713 protein tyrosine kinase activity
1.77 4.57e-09 GO:0005261 cation channel activity
1.76 4.48e-04 GO:0003714 transcription corepressor activity
1.75 3.93e-03 GO:0005267 potassium channel activity
1.74 1.97e-05 GO:0005244 voltage-gated ion channel activity
1.74 1.97e-05 GO:0022832 voltage-gated channel activity
1.73 6.97e-03 GO:0015276 ligand-gated ion channel activity
1.73 6.97e-03 GO:0022834 ligand-gated channel activity
1.72 3.52e-09 GO:0022836 gated channel activity