Motif ID: GUAACAG

Z-value: 0.838


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
hsa-miR-194 MIMAT0000460



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_119738542 19.417 NM_001137554
 MCTS1
malignant T cell amplified sequence 1
chrX_+_119737743 18.530 NM_014060
 MCTS1
malignant T cell amplified sequence 1
chr3_-_195808958 17.705 NM_003234
 TFRC
transferrin receptor (p90, CD71)
chr3_-_195808997 17.461 NM_001128148
 TFRC
transferrin receptor (p90, CD71)
chr3_+_180630054 16.024 NM_001013438
NM_001013439
NM_005087
 FXR1


fragile X mental retardation, autosomal homolog 1


chr12_-_54653317 15.451 NM_001127322
 CBX5
chromobox homolog 5
chr12_-_54653369 14.641 NM_001127321
 CBX5
chromobox homolog 5
chr3_-_113465101 12.918 NM_025146
 NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_85198176 12.480 NM_020122
 KCMF1
potassium channel modulatory factor 1
chr9_+_131445933 12.117 NM_001122821
 SET
SET nuclear oncogene
chr5_+_72112417 11.930 NM_002270
 TNPO1
transportin 1
chr1_+_33116748 11.719 NM_001135255
NM_005610
NM_001135256
 RBBP4


retinoblastoma binding protein 4


chr3_+_152880024 11.649 NM_002886
 RAP2B
RAP2B, member of RAS oncogene family
chr2_-_230786618 11.394 NM_004238
 TRIP12
thyroid hormone receptor interactor 12
chr11_+_74660290 11.181 NM_014752
 LOC653566
SPCS2
signal peptidase complex subunit 2 homolog pseudogene
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr16_-_87903028 10.531 NM_003486
 SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr7_+_77167351 10.090 NM_001131008
NM_001131009
 PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr5_+_72143929 9.882 NM_153188
 TNPO1
transportin 1
chr5_-_98262217 9.670 NM_001270
 CHD1
chromodomain helicase DNA binding protein 1
chr2_-_174828775 9.463 NM_001017371
 SP3
Sp3 transcription factor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 71 entries
enrichment   p-value GO term description
50.16 1.96e-02 GO:0007097 nuclear migration
7.81 3.75e-02 GO:0030522 intracellular receptor mediated signaling pathway
4.60 3.55e-02 GO:0006916 anti-apoptosis
4.58 3.71e-02 GO:0043193 positive regulation of gene-specific transcription
4.20 1.78e-02 GO:0061061 muscle structure development
3.62 4.64e-04 GO:0045892 negative regulation of transcription, DNA-dependent
3.56 8.92e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.55 5.07e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
3.55 6.47e-04 GO:0051253 negative regulation of RNA metabolic process
3.54 2.78e-05 GO:0031327 negative regulation of cellular biosynthetic process
3.47 4.23e-05 GO:0009890 negative regulation of biosynthetic process
3.45 4.04e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.44 3.19e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
3.38 7.90e-04 GO:0010629 negative regulation of gene expression
3.33 1.01e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.32 1.99e-02 GO:0006325 chromatin organization
3.23 1.52e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.99 1.58e-04 GO:0031324 negative regulation of cellular metabolic process
2.98 1.70e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.87 7.09e-03 GO:0010557 positive regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
12.87 1.22e-03 GO:0000118 histone deacetylase complex
11.40 2.51e-03 GO:0017053 transcriptional repressor complex
3.09 1.13e-04 GO:0044451 nucleoplasm part
2.46 8.89e-05 GO:0005654 nucleoplasm
2.08 7.30e-04 GO:0031981 nuclear lumen
1.94 6.71e-04 GO:0043233 organelle lumen
1.93 1.64e-03 GO:0044428 nuclear part
1.90 1.06e-03 GO:0031974 membrane-enclosed lumen
1.89 2.02e-03 GO:0070013 intracellular organelle lumen
1.87 7.16e-03 GO:0005829 cytosol
1.71 4.96e-03 GO:0043234 protein complex
1.56 3.03e-02 GO:0032991 macromolecular complex
1.51 5.34e-04 GO:0005634 nucleus
1.46 3.01e-03 GO:0044422 organelle part
1.45 5.69e-03 GO:0044446 intracellular organelle part
1.31 8.29e-09 GO:0005622 intracellular
1.31 4.12e-08 GO:0044424 intracellular part
1.31 2.89e-03 GO:0043231 intracellular membrane-bounded organelle
1.31 3.09e-03 GO:0043227 membrane-bounded organelle
1.29 6.18e-04 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
27.87 3.12e-02 GO:0008139 nuclear localization sequence binding
6.76 5.77e-03 GO:0051427 hormone receptor binding
6.73 1.92e-02 GO:0035257 nuclear hormone receptor binding
5.19 1.47e-02 GO:0003714 transcription corepressor activity
4.95 3.55e-03 GO:0003682 chromatin binding
3.63 1.61e-02 GO:0016564 transcription repressor activity
3.53 2.09e-02 GO:0016563 transcription activator activity
3.17 1.21e-02 GO:0019904 protein domain specific binding
2.38 6.35e-03 GO:0030528 transcription regulator activity
2.34 1.13e-02 GO:0001071 nucleic acid binding transcription factor activity
2.34 1.13e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.60 2.50e-02 GO:0003676 nucleic acid binding
1.56 1.83e-08 GO:0005515 protein binding
1.23 1.02e-04 GO:0005488 binding