Motif ID: GUAGUGU

Z-value: 1.467


Mature miRNA associated with seed GUAGUGU:

NamemiRBase Accession
hsa-miR-142-3p MIMAT0000434



Activity profile for motif GUAGUGU.

activity profile for motif GUAGUGU


Sorted Z-values histogram for motif GUAGUGU

Sorted Z-values for motif GUAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAGUGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_30712294 39.015 NM_003897
 IER3
immediate early response 3
chr2_+_187464931 31.516 NM_001144999
 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr2_+_187454724 28.994 NM_001145000
NM_002210
 ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr4_+_38869346 26.096 NM_138389
 FAM114A1
family with sequence similarity 114, member A1
chr20_-_43977023 25.329 NM_002999
 SDC4
syndecan 4
chr3_-_123339423 24.459 NM_053031
NM_053032
 MYLK

myosin light chain kinase

chr17_-_48474910 22.268 NM_018509
 LRRC59
leucine rich repeat containing 59
chr19_+_16178170 21.862 NM_001145160
 TPM4
tropomyosin 4
chr19_+_16187047 21.409 NM_003290
 TPM4
tropomyosin 4
chr3_-_123603144 21.316 NM_053025
NM_053026
NM_053027
NM_053028
 MYLK



myosin light chain kinase



chr11_+_57529233 20.303 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
 CTNND1





















catenin (cadherin-associated protein), delta 1





















chr2_-_86948244 20.105 NM_001198954
 RNF103-CHMP3
RNF103-CHMP3 readthrough
chr3_+_187943192 19.953 NM_001167671
 LPP
LIM domain containing preferred translocation partner in lipoma
chr7_-_6523689 18.451 NM_001100603
NM_006854
 KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

chrX_-_153285334 17.999 NM_001025242
NM_001025243
NM_001569
 IRAK1


interleukin-1 receptor-associated kinase 1


chr2_-_86790533 17.715 NM_001005753
NM_001193517
NM_016079
 CHMP3


charged multivesicular body protein 3


chr5_+_95066628 16.748 NM_014899
 RHOBTB3
Rho-related BTB domain containing 3
chr12_-_44200047 16.580 NM_001242397
NM_002822
 TWF1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

chr19_+_54695103 16.270 NM_001077446
 TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr3_+_187930720 15.918 NM_005578
 LPP
LIM domain containing preferred translocation partner in lipoma

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
23.46 2.03e-02 GO:0043401 steroid hormone mediated signaling pathway
13.75 2.88e-02 GO:0009755 hormone-mediated signaling pathway
9.26 4.55e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
8.56 1.77e-02 GO:0022612 gland morphogenesis
3.44 1.95e-02 GO:0016044 cellular membrane organization
3.42 2.07e-02 GO:0061024 membrane organization
3.23 2.52e-04 GO:0016192 vesicle-mediated transport
3.23 4.30e-03 GO:0010629 negative regulation of gene expression
3.20 1.51e-02 GO:0051253 negative regulation of RNA metabolic process
3.09 4.16e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.97 1.97e-03 GO:0046907 intracellular transport
2.85 4.31e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.84 4.61e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.81 3.37e-02 GO:0009890 negative regulation of biosynthetic process
2.73 3.41e-04 GO:0051649 establishment of localization in cell
2.55 6.38e-04 GO:0051641 cellular localization
2.55 2.48e-02 GO:0048468 cell development
2.37 1.91e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.17 1.92e-02 GO:0009653 anatomical structure morphogenesis
2.01 4.57e-03 GO:0048523 negative regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
87.96 2.49e-02 GO:0005642 annulate lamellae
4.66 2.81e-02 GO:0043025 neuronal cell body
4.53 3.50e-02 GO:0044297 cell body
1.47 3.52e-03 GO:0044422 organelle part
1.46 6.94e-03 GO:0044446 intracellular organelle part
1.31 2.43e-04 GO:0043229 intracellular organelle
1.31 2.76e-04 GO:0043226 organelle
1.29 1.34e-02 GO:0043227 membrane-bounded organelle
1.28 2.28e-02 GO:0043231 intracellular membrane-bounded organelle
1.27 3.15e-05 GO:0044424 intracellular part
1.25 5.64e-05 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
87.96 2.88e-04 GO:0004924 oncostatin-M receptor activity
87.96 2.56e-02 GO:0004923 leukemia inhibitory factor receptor activity
26.39 3.26e-02 GO:0046965 retinoid X receptor binding
12.08 3.34e-04 GO:0003707 steroid hormone receptor activity
11.41 4.97e-04 GO:0004879 ligand-dependent nuclear receptor activity
9.43 8.08e-03 GO:0004896 cytokine receptor activity
3.12 2.06e-02 GO:0019904 protein domain specific binding
1.58 1.31e-08 GO:0005515 protein binding
1.24 1.23e-04 GO:0005488 binding