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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HES1.p2

Z-value: 2.018

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_10588451	33.060	NM_002539	ODC1	ornithine decarboxylase 1
chr9_+_91926109	32.218	NM_001827	CKS2	CDC28 protein kinase regulatory subunit 2
chr1_-_94374986	30.923	NM_002061	GCLM	glutamate-cysteine ligase, modifier subunit
chr9_+_131451519	29.113		SET	SET nuclear oncogene
chr1_+_165797060	28.561		UCK2	uridine-cytidine kinase 2
chr1_-_94375028	27.267		GCLM	glutamate-cysteine ligase, modifier subunit
chr1_+_165796652	25.749	NM_012474	UCK2	uridine-cytidine kinase 2
chr6_-_13814546	25.679	NM_001031713	CCDC90A	coiled-coil domain containing 90A
chr1_-_94374949	24.873		GCLM	glutamate-cysteine ligase, modifier subunit
chr12_+_131356640	24.866		RAN	RAN, member RAS oncogene family
chr12_-_123380608	24.776
chr16_+_29817810	24.685	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_-_133340823	23.187	NM_003374	VDAC1	voltage-dependent anion channel 1
chr1_-_11120081	23.164	NM_003132	SRM	spermidine synthase
chrX_+_21958714	22.525	NM_004595	SMS	spermine synthase
chr2_+_113403433	20.918	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr7_+_155089614	20.917		INSIG1	insulin induced gene 1
chr17_+_73257992	20.695		MRPS7	mitochondrial ribosomal protein S7
chr3_+_184081178	20.326	NM_006232	POLR2H	polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_73257944	20.207		MRPS7	mitochondrial ribosomal protein S7
chr22_+_20105076	19.340		RANBP1	RAN binding protein 1
chr17_+_73257745	19.127	NM_015971	MRPS7	mitochondrial ribosomal protein S7
chr14_+_105886146	19.098	NM_001203258 NM_004689	MTA1	metastasis associated 1
chr1_+_220267491	19.035		IARS2	isoleucyl-tRNA synthetase 2, mitochondrial
chr2_-_136633934	18.987		MCM6	minichromosome maintenance complex component 6
chr18_+_12948010	18.895		SEH1L	SEH1-like (S. cerevisiae)
chr9_+_131451470	18.743	NM_003011	SET	SET nuclear oncogene
chr7_+_155089483	18.646	NM_005542 NM_198336 NM_198337	INSIG1	insulin induced gene 1
chr2_+_216176808	18.549		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr4_-_24586015	18.336		DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr20_+_35234210	18.312		C20orf24	chromosome 20 open reading frame 24
chr2_-_136634002	18.184	NM_005915	MCM6	minichromosome maintenance complex component 6
chr17_+_45727274	18.014	NM_002265	KPNB1	karyopherin (importin) beta 1
chr1_-_156721501	17.921	NM_004494	HDGF	hepatoma-derived growth factor
chr19_+_33072087	17.805	NM_004708	PDCD5	programmed cell death 5
chr2_+_181845605	17.233		UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr11_-_14665162	16.931	NM_148976	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1
chr9_+_131451847	16.196		SET	SET nuclear oncogene
chr13_-_99229037	16.070		STK24	serine/threonine kinase 24
chr13_+_27998614	15.925	NM_002097	GTF3A	general transcription factor IIIA
chr19_-_55918980	15.779		UBE2S	ubiquitin-conjugating enzyme E2S
chrX_-_16887974	15.534	NM_001198719	RBBP7	retinoblastoma binding protein 7
chr2_+_181845088	15.439	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr12_+_69979447	15.164	NM_001198842	CCT2	chaperonin containing TCP1, subunit 2 (beta)
chr17_-_73150493	14.953		HN1	hematological and neurological expressed 1
chrX_-_16888442	14.671		RBBP7	retinoblastoma binding protein 7
chr3_+_23847349	14.652	NM_003341 NM_182666	UBE2E1	ubiquitin-conjugating enzyme E2E 1
chr22_+_20105145	14.524		RANBP1	RAN binding protein 1
chr16_-_47007567	14.433	NM_005880	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr8_+_145149978	14.303		CYC1	cytochrome c-1
chr11_+_747428	14.249	NM_006755	TALDO1	transaldolase 1
chr22_+_20105095	14.200		RANBP1	RAN binding protein 1
chr17_+_35849950	14.183	NM_007026	DUSP14	dual specificity phosphatase 14
chr6_+_34204928	14.143		HMGA1	high mobility group AT-hook 1
chr19_-_13068033	13.935	NM_052850	GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr16_-_85832900	13.899	NM_001142288 NM_006067	COX4NB	COX4 neighbor
chr1_+_220267418	13.873	NM_018060	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial
chr19_-_13068008	13.869		GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr8_+_145149936	13.823	NM_001916	CYC1	cytochrome c-1
chr8_+_26149004	13.716	NM_002717	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr2_+_181845803	13.629		UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr1_+_23345928	13.600	NM_001009999 NM_015013	KDM1A	lysine (K)-specific demethylase 1A
chr1_-_53793743	13.569	NM_001018054 NM_004631 NM_017522 NM_033300	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr6_+_34204690	13.503		HMGA1	high mobility group AT-hook 1
chr1_-_11120047	13.487		SRM	spermidine synthase
chr20_+_35234152	13.383		C20orf24	chromosome 20 open reading frame 24
chrX_-_16888462	13.347	NM_002893	RBBP7	retinoblastoma binding protein 7
chr11_+_747424	13.333		TALDO1	transaldolase 1
chr13_-_99229226	13.311	NM_001032296	STK24	serine/threonine kinase 24
chr20_+_57556322	13.240		TH1L	TH1-like (Drosophila)
chr6_+_57037333	13.209		BAG2	BCL2-associated athanogene 2
chr8_+_97274106	13.200		PTDSS1	phosphatidylserine synthase 1
chr6_+_10747991	13.187	NM_001127711 NM_030969	TMEM14B	transmembrane protein 14B
chr1_+_23345985	13.073		KDM1A	lysine (K)-specific demethylase 1A
chr17_+_45608738	12.900		NPEPPS	aminopeptidase puromycin sensitive
chr22_+_39898365	12.570		SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like
chr8_-_97273795	12.545	NM_015942	MTERFD1	MTERF domain containing 1
chr1_+_29063443	12.543	NM_001172828	YTHDF2	YTH domain family, member 2
chr19_+_984316	12.526	NM_024100	WDR18	WD repeat domain 18
chr11_-_93474507	12.509	NM_024116	TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr20_+_35234077	12.345	NM_001199534 NM_018840 NM_199483	C20orf24	chromosome 20 open reading frame 24
chr7_+_98923495	12.295	NM_001190996 NM_006409	ARPC1A	actin related protein 2/3 complex, subunit 1A, 41kDa
chr1_+_29063132	12.261	NM_001173128 NM_016258	YTHDF2	YTH domain family, member 2
chr17_+_66031885	12.258		KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr4_+_57302268	12.247	NM_001079524 NM_001079525	PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr4_-_24586145	12.203		DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr20_+_31407696	12.162	NM_012325	MAPRE1	microtubule-associated protein, RP/EB family, member 1
chrX_-_109561314	12.122	NM_001025580 NM_015365	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr11_+_1968586	12.084		MRPL23	mitochondrial ribosomal protein L23
chr7_-_91763775	12.067		CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1
chr2_-_10588273	12.031		ODC1	ornithine decarboxylase 1
chr12_+_131356617	12.005		RAN	RAN, member RAS oncogene family
chr7_-_87849341	12.000		SRI	sorcin
chr19_-_1652327	11.940	NM_003200	TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr5_-_133340380	11.935		VDAC1	voltage-dependent anion channel 1
chr2_-_198364522	11.922		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr5_-_133340358	11.915		VDAC1	voltage-dependent anion channel 1
chr8_+_26149043	11.845		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr1_-_32801606	11.538	NM_023009	MARCKSL1	MARCKS-like 1
chr7_-_148581379	11.530		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr3_-_33481877	11.519	NM_001128161	UBP1	upstream binding protein 1 (LBP-1a)
chr1_+_154947166	11.480		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr5_-_133340389	11.415		VDAC1	voltage-dependent anion channel 1
chr3_-_33481862	11.321	NM_001128160 NM_014517	UBP1	upstream binding protein 1 (LBP-1a)
chr22_+_20105068	11.317		RANBP1	RAN binding protein 1
chr13_-_99229117	11.274		STK24	serine/threonine kinase 24
chr20_+_11871364	11.244	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr21_+_33031932	11.220	NM_000454	SOD1	superoxide dismutase 1, soluble
chr2_+_187351032	11.195		ZC3H15	zinc finger CCCH-type containing 15
chr19_-_18433847	11.179		LSM4	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_-_148581403	11.178	NM_001203247 NM_001203248 NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr16_-_87903028	11.153	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr1_+_43148359	11.048		YBX1	Y box binding protein 1
chr7_-_148581297	11.037		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581377	11.035		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr4_-_71705188	10.990	NM_001098477	GRSF1	G-rich RNA sequence binding factor 1
chr7_-_102985068	10.903	NM_001129887 NM_014377	DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2
chr1_+_154947147	10.902		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr12_-_46766019	10.899		SLC38A2	solute carrier family 38, member 2
chr12_-_46662779	10.854		SLC38A1	solute carrier family 38, member 1
chr2_-_198364560	10.848		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr9_+_116037913	10.798	NM_001244926 NM_004697	PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr1_+_94883929	10.770	NM_001122674 NM_002858	ABCD3	ATP-binding cassette, sub-family D (ALD), member 3
chr1_-_156722023	10.577	NM_001126051 NM_001126050	HDGF	hepatoma-derived growth factor
chr21_-_40720938	10.571		HMGN1	high mobility group nucleosome binding domain 1
chr7_-_10979752	10.570	NM_002489	NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr5_-_31532164	10.553	NM_001100412 NM_013235	DROSHA	drosha, ribonuclease type III
chr2_+_187350870	10.547	NM_018471	ZC3H15	zinc finger CCCH-type containing 15
chr21_-_18985104	10.506		BTG3	BTG family, member 3
chr11_+_1968499	10.492	NM_021134	MRPL23	mitochondrial ribosomal protein L23
chr17_+_34842472	10.481	NM_004773	ZNHIT3	zinc finger, HIT-type containing 3
chr12_-_46662709	10.476		SLC38A1	solute carrier family 38, member 1
chr19_-_18433933	10.415	NM_001252129 NM_012321	LSM4	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_+_81040515	10.376		CENPN	centromere protein N
chr2_+_181845368	10.360		UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr19_-_14530155	10.301	NM_005804	DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr21_-_18985224	10.279	NM_001130914 NM_006806	BTG3	BTG family, member 3
chr14_-_89883306	10.223	NM_005197	FOXN3	forkhead box N3
chr21_-_18985189	10.218		BTG3	BTG family, member 3
chr19_-_10613767	10.187	NM_203500	KEAP1	kelch-like ECH-associated protein 1
chr1_+_154947116	10.135	NM_001826	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr6_+_34204647	10.107	NM_145901 NM_145902	HMGA1	high mobility group AT-hook 1
chr22_+_32340592	10.070		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr2_-_152684689	10.020		ARL5A	ADP-ribosylation factor-like 5A
chr12_-_46663207	9.973	NM_001077484 NM_030674	SLC38A1	solute carrier family 38, member 1
chr4_-_24586178	9.966	NM_001358	DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr12_-_49525271	9.962	NM_006082	TUBA1B	tubulin, alpha 1b
chr17_+_35849997	9.952		DUSP14	dual specificity phosphatase 14
chr5_+_170814707	9.937	NM_001037738 NM_002520 NM_199185	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr19_+_8509869	9.919		HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr20_+_47662782	9.896	NM_001316	CSE1L	CSE1 chromosome segregation 1-like (yeast)
chr7_+_87505543	9.888	NM_006716	DBF4	DBF4 homolog (S. cerevisiae)
chr7_-_99698278	9.851	NM_182776	MCM7	minichromosome maintenance complex component 7
chr4_+_57301898	9.844	NM_006452	PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr7_-_10979683	9.831		NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr21_-_40721010	9.824	NM_004965	HMGN1	high mobility group nucleosome binding domain 1
chr17_+_26646120	9.766	NM_014573	TMEM97	transmembrane protein 97
chr1_+_214454276	9.733	NM_020197	SMYD2	SET and MYND domain containing 2
chrX_-_16888175	9.729		RBBP7	retinoblastoma binding protein 7
chr8_+_87526646	9.727	NM_003909	CPNE3	copine III
chr21_-_30445949	9.722		CCT8	chaperonin containing TCP1, subunit 8 (theta)
chr19_+_10982369	9.721		CARM1	coactivator-associated arginine methyltransferase 1
chr1_+_43824598	9.664	NM_001255	CDC20	cell division cycle 20 homolog (S. cerevisiae)
chr12_+_104609501	9.664	NM_001093771	TXNRD1	thioredoxin reductase 1
chr16_+_57481336	9.599	NM_020312	COQ9	coenzyme Q9 homolog (S. cerevisiae)
chr12_+_131356557	9.574	NM_006325	RAN	RAN, member RAS oncogene family
chr21_-_30445913	9.547		CCT8	chaperonin containing TCP1, subunit 8 (theta)
chr1_+_41445402	9.541		CTPS	CTP synthase
chr12_-_122712019	9.539	NM_019887 NM_138929	DIABLO	diablo, IAP-binding mitochondrial protein
chr6_-_17706617	9.528	NM_005124	NUP153	nucleoporin 153kDa
chr17_+_7476023	9.509	NM_001204510 NM_001416	EIF4A1	eukaryotic translation initiation factor 4A1
chr21_-_40555342	9.501	NM_003720 NM_203433	PSMG1	proteasome (prosome, macropain) assembly chaperone 1
chr17_-_57184034	9.490		TRIM37	tripartite motif containing 37
chr7_+_75677356	9.403	NM_005918	MDH2	malate dehydrogenase 2, NAD (mitochondrial)
chr5_-_79950783	9.376	NM_000791	DHFR	dihydrofolate reductase
chr16_-_47007483	9.275		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr19_+_10982244	9.163	NM_199141	CARM1	coactivator-associated arginine methyltransferase 1
chr11_-_2950593	9.152	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr7_+_100303673	9.136	NM_005837	POP7	processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr13_+_76123885	9.126	NM_006002	UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr17_-_57184174	9.121	NM_001005207 NM_015294	TRIM37	tripartite motif containing 37
chr5_-_68665316	9.097	NM_003187 NM_016283	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr22_+_32340435	8.995	NM_003405	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chrX_-_109561298	8.953		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr12_+_3068442	8.936	NM_003213 NM_201441 NM_201443	TEAD4	TEA domain family member 4
chr8_-_102217519	8.936		ZNF706	zinc finger protein 706
chr4_-_185655215	8.915	NM_024629	MLF1IP	MLF1 interacting protein
chr2_-_240964717	8.905		NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr15_-_77363451	8.899		TSPAN3	tetraspanin 3
chr7_+_56119377	8.881	NM_001009186 NM_001762	CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)
chr5_+_170814952	8.832		NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chrX_+_23685613	8.810		PRDX4	peroxiredoxin 4
chr11_-_47447457	8.785		PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr3_-_186524483	8.754	NM_181573	RFC4	replication factor C (activator 1) 4, 37kDa
chr2_+_85766291	8.716		MAT2A	methionine adenosyltransferase II, alpha
chr17_-_40075153	8.683		ACLY	ATP citrate lyase
chr4_-_84205897	8.621		COQ2	coenzyme Q2 homolog, prenyltransferase (yeast)
chr12_+_49658862	8.606	NM_032704	TUBA1C	tubulin, alpha 1c
chr7_+_16685757	8.604	NM_001159767 NM_014038	BZW2	basic leucine zipper and W2 domains 2
chr3_-_47823386	8.567	NM_003074	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.55	1.75e-60	GO:0044237	cellular metabolic process
1.45	1.21e-51	GO:0008152	metabolic process
1.49	1.09e-49	GO:0044238	primary metabolic process
1.25	1.23e-45	GO:0009987	cellular process
1.74	7.10e-42	GO:0006807	nitrogen compound metabolic process
1.60	1.09e-41	GO:0044260	cellular macromolecule metabolic process
1.74	1.04e-40	GO:0034641	cellular nitrogen compound metabolic process
1.80	4.11e-39	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51	2.19e-36	GO:0043170	macromolecule metabolic process
1.78	6.57e-28	GO:0090304	nucleic acid metabolic process
1.71	8.15e-26	GO:0044249	cellular biosynthetic process
1.68	2.93e-25	GO:0009058	biosynthetic process
1.60	1.32e-19	GO:0044267	cellular protein metabolic process
1.70	3.69e-18	GO:0010467	gene expression
1.72	8.65e-18	GO:0016070	RNA metabolic process
1.49	5.67e-16	GO:0019538	protein metabolic process
1.51	1.57e-15	GO:0071841	cellular component organization or biogenesis at cellular level
1.68	1.79e-15	GO:0009059	macromolecule biosynthetic process
1.44	1.84e-15	GO:0071840	cellular component organization or biogenesis
1.91	3.09e-15	GO:0007049	cell cycle
2.17	6.52e-15	GO:0006396	RNA processing
1.67	1.04e-14	GO:0034645	cellular macromolecule biosynthetic process
2.20	5.28e-14	GO:0000278	mitotic cell cycle
1.42	2.00e-13	GO:0016043	cellular component organization
1.65	4.04e-13	GO:0006996	organelle organization
1.48	5.00e-13	GO:0071842	cellular component organization at cellular level
2.05	7.42e-13	GO:0022403	cell cycle phase
1.93	2.67e-12	GO:0022402	cell cycle process
2.09	1.09e-11	GO:0006259	DNA metabolic process
1.92	1.65e-11	GO:0046907	intracellular transport
1.56	4.80e-11	GO:0044281	small molecule metabolic process
2.49	1.35e-10	GO:0051325	interphase
2.50	1.58e-10	GO:0051329	interphase of mitotic cell cycle
1.67	1.72e-10	GO:0051641	cellular localization
1.64	5.49e-10	GO:0033036	macromolecule localization
1.97	7.12e-10	GO:0051726	regulation of cell cycle
2.06	7.28e-10	GO:0016071	mRNA metabolic process
1.82	1.54e-09	GO:0033554	cellular response to stress
1.69	2.42e-09	GO:0051649	establishment of localization in cell
1.68	9.71e-09	GO:0008104	protein localization
1.92	1.50e-08	GO:0051276	chromosome organization
1.99	3.54e-08	GO:0006974	response to DNA damage stimulus
1.49	3.57e-08	GO:0006464	protein modification process
1.74	4.87e-08	GO:0045184	establishment of protein localization
1.75	5.05e-08	GO:0015031	protein transport
2.15	6.04e-08	GO:0006397	mRNA processing
1.46	6.63e-08	GO:0043412	macromolecule modification
1.43	1.10e-07	GO:0048523	negative regulation of cellular process
1.39	2.37e-07	GO:0048522	positive regulation of cellular process
2.55	2.60e-07	GO:0071843	cellular component biogenesis at cellular level
2.25	3.02e-07	GO:0006412	translation
2.56	3.69e-07	GO:0000375	RNA splicing, via transesterification reactions
1.39	4.14e-07	GO:0048519	negative regulation of biological process
2.19	4.40e-07	GO:0009259	ribonucleotide metabolic process
2.24	5.06e-07	GO:0008380	RNA splicing
1.52	7.01e-07	GO:0009056	catabolic process
1.94	7.98e-07	GO:0034621	cellular macromolecular complex subunit organization
1.58	8.57e-07	GO:0044085	cellular component biogenesis
2.54	1.12e-06	GO:0022613	ribonucleoprotein complex biogenesis
2.27	1.30e-06	GO:0010608	posttranscriptional regulation of gene expression
1.62	1.36e-06	GO:0032268	regulation of cellular protein metabolic process
2.52	1.37e-06	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.52	1.37e-06	GO:0000398	nuclear mRNA splicing, via spliceosome
2.10	1.44e-06	GO:0044419	interspecies interaction between organisms
2.09	1.66e-06	GO:0016568	chromatin modification
1.59	2.09e-06	GO:0051246	regulation of protein metabolic process
2.09	2.87e-06	GO:0051301	cell division
1.35	2.91e-06	GO:0048518	positive regulation of biological process
2.55	3.20e-06	GO:0006260	DNA replication
1.77	3.57e-06	GO:0046483	heterocycle metabolic process
2.14	3.81e-06	GO:0009150	purine ribonucleotide metabolic process
2.23	5.08e-06	GO:0034660	ncRNA metabolic process
1.56	5.47e-06	GO:0044248	cellular catabolic process
2.14	9.34e-06	GO:0009141	nucleoside triphosphate metabolic process
1.90	9.39e-06	GO:0006325	chromatin organization
2.06	1.23e-05	GO:0006281	DNA repair
1.63	1.48e-05	GO:0008219	cell death
1.64	1.85e-05	GO:0043933	macromolecular complex subunit organization
1.63	2.05e-05	GO:0016265	death
2.12	2.17e-05	GO:0009144	purine nucleoside triphosphate metabolic process
2.00	2.70e-05	GO:0034622	cellular macromolecular complex assembly
1.79	2.74e-05	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.68	3.90e-05	GO:0006915	apoptosis
2.10	4.10e-05	GO:0009199	ribonucleoside triphosphate metabolic process
1.15	4.39e-05	GO:0065007	biological regulation
1.83	4.62e-05	GO:0044283	small molecule biosynthetic process
1.67	4.95e-05	GO:0012501	programmed cell death
2.46	5.27e-05	GO:0043687	post-translational protein modification
2.74	5.48e-05	GO:0042254	ribosome biogenesis
1.28	5.52e-05	GO:0060255	regulation of macromolecule metabolic process
2.00	5.73e-05	GO:0010564	regulation of cell cycle process
1.93	6.46e-05	GO:0006091	generation of precursor metabolites and energy
1.16	6.82e-05	GO:0050789	regulation of biological process
2.14	6.83e-05	GO:0007346	regulation of mitotic cell cycle
1.16	6.85e-05	GO:0050794	regulation of cellular process
1.58	8.48e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.90	8.64e-05	GO:0016032	viral reproduction
2.08	8.86e-05	GO:0009205	purine ribonucleoside triphosphate metabolic process
2.86	1.29e-04	GO:0009260	ribonucleotide biosynthetic process
1.71	1.34e-04	GO:0009057	macromolecule catabolic process
1.66	1.44e-04	GO:0042180	cellular ketone metabolic process
1.79	1.46e-04	GO:0006753	nucleoside phosphate metabolic process
1.79	1.46e-04	GO:0009117	nucleotide metabolic process
1.86	1.56e-04	GO:0072521	purine-containing compound metabolic process
1.77	1.59e-04	GO:0044265	cellular macromolecule catabolic process
1.54	2.15e-04	GO:0009892	negative regulation of metabolic process
1.77	2.18e-04	GO:0070727	cellular macromolecule localization
1.24	2.42e-04	GO:0019222	regulation of metabolic process
1.65	2.78e-04	GO:0065003	macromolecular complex assembly
2.19	2.84e-04	GO:0071156	regulation of cell cycle arrest
1.76	3.27e-04	GO:0034613	cellular protein localization
1.86	5.47e-04	GO:0006886	intracellular protein transport
2.19	5.71e-04	GO:0000075	cell cycle checkpoint
1.81	7.03e-04	GO:0000279	M phase
1.88	7.32e-04	GO:0044271	cellular nitrogen compound biosynthetic process
2.11	7.73e-04	GO:0018130	heterocycle biosynthetic process
1.85	8.42e-04	GO:0006163	purine nucleotide metabolic process
2.24	8.97e-04	GO:0034470	ncRNA processing
2.34	9.51e-04	GO:0006417	regulation of translation
1.62	9.73e-04	GO:0019752	carboxylic acid metabolic process
1.62	9.73e-04	GO:0043436	oxoacid metabolic process
2.57	1.13e-03	GO:0050657	nucleic acid transport
2.57	1.13e-03	GO:0050658	RNA transport
2.57	1.13e-03	GO:0051236	establishment of RNA localization
1.45	1.25e-03	GO:0031325	positive regulation of cellular metabolic process
2.11	1.34e-03	GO:0051186	cofactor metabolic process
1.89	1.48e-03	GO:0006520	cellular amino acid metabolic process
1.26	1.59e-03	GO:0006810	transport
1.49	1.67e-03	GO:0042981	regulation of apoptosis
1.26	1.96e-03	GO:0051234	establishment of localization
2.39	2.29e-03	GO:0000082	G1/S transition of mitotic cell cycle
2.49	2.56e-03	GO:0006403	RNA localization
1.23	2.58e-03	GO:0031323	regulation of cellular metabolic process
1.23	2.60e-03	GO:0051179	localization
2.73	2.66e-03	GO:0009152	purine ribonucleotide biosynthetic process
1.47	2.77e-03	GO:0043067	regulation of programmed cell death
1.64	3.02e-03	GO:0071822	protein complex subunit organization
1.58	3.14e-03	GO:0006082	organic acid metabolic process
1.70	3.42e-03	GO:0009308	amine metabolic process
1.51	3.52e-03	GO:0031324	negative regulation of cellular metabolic process
1.74	3.88e-03	GO:0044262	cellular carbohydrate metabolic process
1.46	4.29e-03	GO:0010941	regulation of cell death
2.36	4.68e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.46	4.81e-03	GO:0022607	cellular component assembly
1.61	4.82e-03	GO:0005975	carbohydrate metabolic process
1.76	4.94e-03	GO:0044106	cellular amine metabolic process
2.20	5.04e-03	GO:0016570	histone modification
1.20	5.18e-03	GO:0051716	cellular response to stimulus
1.43	5.63e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.83	6.20e-03	GO:0018193	peptidyl-amino acid modification
1.22	6.30e-03	GO:0080090	regulation of primary metabolic process
3.51	6.38e-03	GO:0006458	'de novo' protein folding
1.89	6.39e-03	GO:0000087	M phase of mitotic cell cycle
2.18	6.89e-03	GO:0006913	nucleocytoplasmic transport
1.41	7.34e-03	GO:0009893	positive regulation of metabolic process
2.50	7.38e-03	GO:0051320	S phase
2.16	8.03e-03	GO:0016569	covalent chromatin modification
2.83	8.12e-03	GO:0009142	nucleoside triphosphate biosynthetic process
2.15	9.34e-03	GO:0051169	nuclear transport
1.52	9.83e-03	GO:0031399	regulation of protein modification process
1.46	1.05e-02	GO:0032774	RNA biosynthetic process
2.22	1.05e-02	GO:0022415	viral reproductive process
2.11	1.19e-02	GO:0022411	cellular component disassembly
2.11	1.19e-02	GO:0071845	cellular component disassembly at cellular level
1.53	1.22e-02	GO:0071844	cellular component assembly at cellular level
4.11	1.29e-02	GO:0050773	regulation of dendrite development
2.44	1.32e-02	GO:0031570	DNA integrity checkpoint
1.83	1.42e-02	GO:0006511	ubiquitin-dependent protein catabolic process
2.46	1.56e-02	GO:0000084	S phase of mitotic cell cycle
2.04	1.60e-02	GO:0006605	protein targeting
2.30	1.61e-02	GO:0019058	viral infectious cycle
2.15	1.61e-02	GO:0009165	nucleotide biosynthetic process
2.65	1.85e-02	GO:0018196	peptidyl-asparagine modification
2.65	1.85e-02	GO:0018279	protein N-linked glycosylation via asparagine
2.32	1.93e-02	GO:0046034	ATP metabolic process
2.06	2.10e-02	GO:0034404	nucleobase, nucleoside and nucleotide biosynthetic process
2.06	2.10e-02	GO:0034654	nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
1.56	2.51e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.55	2.55e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.63	2.61e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.25	2.66e-02	GO:0006310	DNA recombination
1.80	2.67e-02	GO:0019941	modification-dependent protein catabolic process
2.23	3.13e-02	GO:0006006	glucose metabolic process
1.54	3.16e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.97	3.26e-02	GO:0009146	purine nucleoside triphosphate catabolic process
1.79	3.28e-02	GO:0043632	modification-dependent macromolecule catabolic process
2.37	3.30e-02	GO:0051188	cofactor biosynthetic process
2.09	3.36e-02	GO:0006732	coenzyme metabolic process
2.37	4.71e-02	GO:0051028	mRNA transport
1.94	4.74e-02	GO:0009143	nucleoside triphosphate catabolic process
1.94	4.74e-02	GO:0009154	purine ribonucleotide catabolic process
2.16	4.83e-02	GO:0016051	carbohydrate biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.31	8.44e-83	GO:0044424	intracellular part
1.29	1.70e-78	GO:0005622	intracellular
1.41	6.39e-62	GO:0005737	cytoplasm
1.58	1.62e-59	GO:0044446	intracellular organelle part
1.33	3.42e-58	GO:0043229	intracellular organelle
1.33	5.58e-58	GO:0043226	organelle
1.57	9.83e-58	GO:0044422	organelle part
1.37	2.07e-57	GO:0043227	membrane-bounded organelle
1.37	2.22e-57	GO:0043231	intracellular membrane-bounded organelle
1.49	1.60e-48	GO:0044444	cytoplasmic part
1.96	9.03e-44	GO:0044428	nuclear part
1.90	3.87e-42	GO:0031974	membrane-enclosed lumen
1.89	2.60e-39	GO:0070013	intracellular organelle lumen
1.93	3.86e-39	GO:0005829	cytosol
1.87	5.59e-39	GO:0043233	organelle lumen
1.94	2.43e-34	GO:0031981	nuclear lumen
1.42	5.44e-31	GO:0005634	nucleus
1.96	1.37e-24	GO:0005654	nucleoplasm
1.51	9.63e-24	GO:0032991	macromolecular complex
2.13	3.68e-17	GO:0031967	organelle envelope
1.08	7.48e-17	GO:0044464	cell part
1.08	7.97e-17	GO:0005623	cell
2.09	2.14e-16	GO:0031975	envelope
1.77	3.68e-16	GO:0005739	mitochondrion
2.30	1.51e-15	GO:0005730	nucleolus
1.47	2.33e-14	GO:0043228	non-membrane-bounded organelle
1.47	2.33e-14	GO:0043232	intracellular non-membrane-bounded organelle
2.21	7.24e-14	GO:0030529	ribonucleoprotein complex
1.44	9.19e-14	GO:0043234	protein complex
1.53	1.56e-13	GO:0031090	organelle membrane
1.98	2.25e-12	GO:0044429	mitochondrial part
2.11	2.10e-10	GO:0005740	mitochondrial envelope
2.07	3.47e-09	GO:0031966	mitochondrial membrane
2.13	1.45e-07	GO:0019866	organelle inner membrane
1.46	6.84e-07	GO:0012505	endomembrane system
2.10	1.91e-06	GO:0005743	mitochondrial inner membrane
1.67	7.08e-06	GO:0044451	nucleoplasm part
3.09	2.68e-05	GO:0046930	pore complex
2.14	3.47e-05	GO:0005635	nuclear envelope
1.72	4.50e-05	GO:0005694	chromosome
3.16	1.58e-04	GO:0005643	nuclear pore
1.60	3.38e-04	GO:0015630	microtubule cytoskeleton
2.17	6.80e-04	GO:0005819	spindle
1.94	1.52e-03	GO:0005759	mitochondrial matrix
1.55	1.57e-03	GO:0042175	nuclear membrane-endoplasmic reticulum network
5.27	1.76e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.99	2.03e-03	GO:0005813	centrosome
1.66	2.72e-03	GO:0044427	chromosomal part
1.54	2.75e-03	GO:0005789	endoplasmic reticulum membrane
1.49	5.23e-03	GO:0044432	endoplasmic reticulum part
1.40	6.66e-03	GO:0005783	endoplasmic reticulum
2.29	7.96e-03	GO:0044455	mitochondrial membrane part
2.50	9.04e-03	GO:0016585	chromatin remodeling complex
1.70	2.12e-02	GO:0005815	microtubule organizing center
1.96	2.50e-02	GO:0031252	cell leading edge
4.49	2.93e-02	GO:0031519	PcG protein complex
2.09	2.98e-02	GO:0031965	nuclear membrane
1.93	3.62e-02	GO:0005840	ribosome
3.09	4.40e-02	GO:0016469	proton-transporting two-sector ATPase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.46	1.02e-58	GO:0005515	protein binding
1.20	6.07e-38	GO:0005488	binding
2.08	1.52e-18	GO:0003723	RNA binding
1.55	4.68e-16	GO:0000166	nucleotide binding
1.30	2.42e-14	GO:0003824	catalytic activity
1.46	1.48e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.46	2.04e-08	GO:0032553	ribonucleotide binding
1.46	2.04e-08	GO:0032555	purine ribonucleotide binding
1.45	2.30e-08	GO:0017076	purine nucleotide binding
1.31	1.17e-07	GO:0003676	nucleic acid binding
1.49	1.24e-07	GO:0032559	adenyl ribonucleotide binding
1.49	1.25e-07	GO:0030554	adenyl nucleotide binding
1.50	1.37e-07	GO:0005524	ATP binding
1.72	4.57e-07	GO:0019899	enzyme binding
1.40	2.52e-05	GO:0016740	transferase activity
1.79	8.20e-05	GO:0016874	ligase activity
2.24	1.70e-04	GO:0003682	chromatin binding
2.36	6.21e-04	GO:0008022	protein C-terminus binding
1.73	1.02e-03	GO:0019904	protein domain specific binding
1.75	3.35e-03	GO:0003712	transcription cofactor activity
1.74	3.68e-03	GO:0000988	protein binding transcription factor activity
1.74	3.68e-03	GO:0000989	transcription factor binding transcription factor activity
2.82	3.91e-03	GO:0042393	histone binding
1.46	4.22e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
2.57	1.35e-02	GO:0008565	protein transporter activity
2.35	1.52e-02	GO:0016779	nucleotidyltransferase activity
2.58	1.93e-02	GO:0008135	translation factor activity, nucleic acid binding
2.51	2.04e-02	GO:0035257	nuclear hormone receptor binding
2.59	2.74e-02	GO:0003729	mRNA binding
1.44	3.21e-02	GO:0016462	pyrophosphatase activity
1.44	3.82e-02	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.73	4.03e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.44	4.22e-02	GO:0017111	nucleoside-triphosphatase activity
1.43	4.53e-02	GO:0016817	hydrolase activity, acting on acid anhydrides