Motif ID: HLF.p2

Z-value: 1.143


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HLFchr17_+_533449660.161.8e-02Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_72088507 15.625 NM_001126102
NM_005143
 HP

haptoglobin

chr9_+_117085302 15.053 NM_000607
 ORM1
orosomucoid 1
chr9_+_111624545 14.958 NM_006687
 ACTL7A
actin-like 7A
chr6_+_131894343 14.815 NM_000045
NM_001244438
 ARG1

arginase, liver

chr2_+_113885137 14.493 NM_173842
 IL1RN
interleukin 1 receptor antagonist
chr9_+_117092068 13.392 NM_000608
 ORM2
orosomucoid 2
chr20_+_47895168 13.159 ZNFX1-AS1
ZNFX1 antisense RNA 1 (non-protein coding)
chr3_-_49726081 13.078 NM_020998
 MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_-_55866972 13.049 CES1
carboxylesterase 1
chr3_-_47957475 12.877


chr9_+_36169384 12.832 NM_005893
 CCIN
calicin
chr16_-_55867016 12.728 NM_001025194
NM_001025195
NM_001266
 CES1


carboxylesterase 1


chr14_-_70263871 12.413 NM_003049
 SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr14_-_23284617 12.172 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_+_72097124 11.528 NM_020995
 HPR
haptoglobin-related protein
chr5_-_140012730 11.369 CD14
CD14 molecule
chr19_-_40919270 10.748 NM_020956
NM_181882
 PRX

periaxin

chr3_+_186330844 10.392 NM_001622
 AHSG
alpha-2-HS-glycoprotein
chr12_+_112856701 10.234 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr5_-_140013034 10.204 NM_000591
 CD14
CD14 molecule

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
21.88 7.75e-05 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
19.45 2.26e-04 GO:0048880 sensory system development
19.45 2.26e-04 GO:0048892 lateral line nerve development
19.45 2.26e-04 GO:0048895 lateral line nerve glial cell differentiation
19.45 2.26e-04 GO:0048925 lateral line system development
19.45 2.26e-04 GO:0048937 lateral line nerve glial cell development
19.45 2.26e-04 GO:0050935 iridophore differentiation
18.56 2.91e-05 GO:0060600 dichotomous subdivision of an epithelial terminal unit
14.58 2.28e-03 GO:0048846 axon extension involved in axon guidance
14.58 2.28e-03 GO:0090184 positive regulation of kidney development
13.61 5.03e-04 GO:0048485 sympathetic nervous system development
11.67 1.13e-02 GO:0030513 positive regulation of BMP signaling pathway
11.67 1.13e-02 GO:0048484 enteric nervous system development
8.88 1.51e-02 GO:0090183 regulation of kidney development
8.64 4.18e-03 GO:0048483 autonomic nervous system development
8.17 2.79e-02 GO:0018149 peptide cross-linking
6.48 4.35e-02 GO:0021675 nerve development
3.95 3.05e-09 GO:0006954 inflammatory response
3.23 5.01e-05 GO:0055065 metal ion homeostasis
3.18 5.53e-03 GO:0072507 divalent inorganic cation homeostasis

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
4.97 4.53e-02 GO:0031093 platelet alpha granule lumen
4.61 3.27e-02 GO:0031091 platelet alpha granule
2.62 8.91e-11 GO:0005615 extracellular space
2.29 1.96e-09 GO:0044421 extracellular region part
1.87 8.03e-10 GO:0005576 extracellular region
1.63 3.82e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
6.98 1.25e-04 GO:0008009 chemokine activity
6.86 4.38e-05 GO:0042379 chemokine receptor binding
3.05 1.04e-02 GO:0001664 G-protein-coupled receptor binding