Motif ID: HMGA1,2.p2

Z-value: 1.133


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMGA2chr12_+_662188790.212.1e-03Click!
HMGA1chr6_+_34204928-0.082.4e-01Click!


Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_88450243 51.498 SPARCL1
SPARC-like 1 (hevin)
chr4_-_88450601 22.265 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr4_+_88896801 18.506 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr4_+_88896868 17.536 SPP1
secreted phosphoprotein 1
chr4_+_88896838 16.938 SPP1
secreted phosphoprotein 1
chr10_-_118680978 14.791 KIAA1598
KIAA1598
chr2_-_216259197 14.702 FN1
fibronectin 1
chr1_-_163113938 13.164 RGS5
regulator of G-protein signaling 5
chr10_+_5005453 12.859 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr12_+_48516428 12.784 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr10_+_5005601 11.153 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chrX_-_137949716 11.121 NM_001139502
FGF13
fibroblast growth factor 13
chr7_+_23286420 10.007 GPNMB
glycoprotein (transmembrane) nmb
chr2_-_175712276 10.005 NM_001206602
CHN1
chimerin (chimaerin) 1
chr10_+_5005685 9.970 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr3_-_195310985 9.778 NM_001647
APOD
apolipoprotein D
chr7_+_23286384 9.646 GPNMB
glycoprotein (transmembrane) nmb
chrX_+_83116153 9.569 NM_021118
CYLC1
cylicin, basic protein of sperm head cytoskeleton 1
chr7_+_23286277 9.482 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chrX_+_103031797 9.305 PLP1
proteolipid protein 1
chr10_-_5045967 8.934 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr5_+_140797243 8.794 NM_018927
PCDHGB7
protocadherin gamma subfamily B, 7
chr12_-_91573264 8.770 NM_133503
DCN
decorin
chr13_-_78493902 8.737 NM_001201397
EDNRB
endothelin receptor type B
chr3_-_195310770 8.516 APOD
apolipoprotein D
chrX_-_10645726 8.094 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr1_-_170038055 8.078 NM_001204517
KIFAP3
kinesin-associated protein 3
chr2_-_224467142 8.046 NM_003469
SCG2
secretogranin II
chr4_+_88896899 7.961 SPP1
secreted phosphoprotein 1
chrX_-_114252132 7.953 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chr1_+_196621007 7.902 NM_000186
NM_001014975
CFH

complement factor H

chr2_-_224467049 7.849 SCG2
secretogranin II
chr4_+_124317884 7.469 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_-_78666943 7.163 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr11_-_114466471 7.116 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr10_-_101841593 6.959 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr3_+_361365 6.937 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr5_+_40909558 6.835 NM_000587
C7
complement component 7
chr8_+_80523376 6.795 STMN2
stathmin-like 2
chrX_-_102319080 6.595 BEX1
brain expressed, X-linked 1
chr15_-_99789585 6.592 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr3_-_165555252 6.557 NM_000055
BCHE
butyrylcholinesterase
chr5_+_173472692 6.520 NM_015980
HMP19
HMP19 protein
chr12_+_101988746 6.416 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr19_-_20844312 6.400 NM_001076675
NM_145297
ZNF626

zinc finger protein 626

chr5_+_71502700 6.345 MAP1B
microtubule-associated protein 1B
chr11_+_131240370 6.230 NM_001048209
NTM
neurotrimin
chr5_+_40909617 6.164 C7
complement component 7
chrX_-_10535476 6.149 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr11_-_114466397 6.096 FAM55D
family with sequence similarity 55, member D
chr5_+_36606667 6.092 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_90759446 6.078 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_+_121513158 6.009 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr4_-_87281374 5.957 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr5_-_24645084 5.946 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr4_-_174320616 5.894 NM_007281
SCRG1
stimulator of chondrogenesis 1
chr5_-_35118223 5.888 NM_001204314
NM_001204315
NM_001204316
NM_001204317
NM_001204318
PRLR




prolactin receptor




chr10_-_69597768 5.865 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr2_-_188419049 5.840 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_+_23286386 5.811 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286390 5.755 GPNMB
glycoprotein (transmembrane) nmb
chrX_+_105937067 5.678 NM_024539
RNF128
ring finger protein 128
chr2_-_224467095 5.615 SCG2
secretogranin II
chr8_-_110693233 5.608 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr19_-_48614013 5.591 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr11_+_60260250 5.589 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr5_+_36608430 5.478 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_120651019 5.428 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr4_+_41700736 5.428 LIMCH1
LIM and calponin homology domains 1
chr8_-_38008332 5.389 NM_000349
STAR
steroidogenic acute regulatory protein
chr1_+_150480584 5.380 ECM1
extracellular matrix protein 1
chr3_-_79817058 5.338 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_-_7682741 5.290 ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chrX_+_49160124 5.262 NM_001098413
GAGE10
G antigen 10
chr9_-_21187529 5.220 NM_021068
IFNA4
interferon, alpha 4
chr4_+_71263598 5.210 NM_021225
PROL1
proline rich, lacrimal 1
chr4_+_169418167 5.186 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr2_-_242556883 5.184 NM_001164356
THAP4
THAP domain containing 4
chr18_-_61329113 5.126 NM_006919
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr13_+_49280619 5.109 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr5_-_77844975 5.107 LHFPL2
lipoma HMGIC fusion partner-like 2
chr1_+_150480486 5.060 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chrX_+_91089658 5.055 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr4_+_62362838 5.025 NM_015236
LPHN3
latrophilin 3
chr4_+_71337674 4.976 NM_001145007
MUC7
mucin 7, secreted
chr10_+_5238756 4.922 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr4_+_71337833 4.891 NM_152291
MUC7
mucin 7, secreted
chrX_+_103031753 4.864 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr16_-_11375094 4.813 NM_002761
PRM1
protamine 1
chr5_-_160279045 4.809 NM_025153
ATP10B
ATPase, class V, type 10B
chr9_-_14398981 4.807 NM_001190738
NFIB
nuclear factor I/B
chr1_-_160492982 4.802 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr11_-_128894008 4.789 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr2_+_234590583 4.768 NM_019077
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr11_-_88781039 4.748 NM_001143831
GRM5
glutamate receptor, metabotropic 5
chrX_-_13835012 4.677 GPM6B
glycoprotein M6B
chr12_+_32654976 4.657 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_-_95657255 4.649 NM_001243571
NM_016156
NM_201278
NM_201281
MTMR2



myotubularin related protein 2



chr3_+_159557745 4.575 SCHIP1
schwannomin interacting protein 1
chrX_+_49197555 4.557 NM_012196
NM_001472
NM_001127200
NM_001098407
NM_001127212
GAGE8
GAGE2C
GAGE2E
GAGE12J
GAGE2D
GAGE2A
G antigen 8
G antigen 2C
G antigen 2E
G antigen 12J
G antigen 2D
G antigen 2A
chr12_-_9268513 4.548 A2M
alpha-2-macroglobulin
chrX_+_49207115 4.500 NM_012196
NM_001472
NM_001127200
NM_001098407
NM_001127212
GAGE8
GAGE2C
GAGE2E
GAGE2D
GAGE2A
G antigen 8
G antigen 2C
G antigen 2E
G antigen 2D
G antigen 2A
chr1_-_163172863 4.479 NM_003617
RGS5
regulator of G-protein signaling 5
chr1_-_153085963 4.407 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr4_+_71248794 4.373 NM_006685
SMR3B
submaxillary gland androgen regulated protein 3B
chr2_+_204192915 4.342 NM_005759
ABI2
abl-interactor 2
chr5_-_177207465 4.339 NM_173663
FAM153A
family with sequence similarity 153, member A
chr12_+_48513012 4.319 NM_000289
PFKM
phosphofructokinase, muscle
chrX_+_49226137 4.318 NM_001472
NM_001098407
GAGE2C
GAGE2E
GAGE2D
GAGE2A
G antigen 2C
G antigen 2E
G antigen 2D
G antigen 2A
chr5_+_36606456 4.303 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr3_+_158991035 4.296 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chrX_+_49178508 4.292 NM_001098406
GAGE1
GAGE4
GAGE5
GAGE6
GAGE12J
G antigen 1
G antigen 4
G antigen 5
G antigen 6
G antigen 12J
chrX_+_49188092 4.289 NM_012196
NM_001127200
NM_001098412
GAGE8
GAGE2C
GAGE2E
GAGE13
GAGE2A
G antigen 8
G antigen 2C
G antigen 2E
G antigen 13
G antigen 2A
chrX_+_49216616 4.277 NM_012196
NM_001472
NM_001474
NM_001475
NM_021123
NM_001477
NM_001127200
NM_001127212
GAGE8
GAGE1
GAGE2C
GAGE4
GAGE5
GAGE6
GAGE7
GAGE12I
GAGE2E
GAGE12B
GAGE2A
G antigen 8
G antigen 1
G antigen 2C
G antigen 4
G antigen 5
G antigen 6
G antigen 7
G antigen 12I
G antigen 2E
G antigen 12B
G antigen 2A
chr15_+_42696957 4.224 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr15_-_45670955 4.138 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_+_20817766 4.112 NM_001144924
NM_001199053
NM_030941
LOC81691


exonuclease NEF-sp


chr18_-_64271215 4.057 NM_021153
CDH19
cadherin 19, type 2
chr15_-_74659926 4.040 NM_000781
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr1_-_57045129 4.034 PPAP2B
phosphatidic acid phosphatase type 2B
chr22_-_36236421 4.030 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr4_-_87028805 4.026 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr2_+_210444154 4.026 MAP2
microtubule-associated protein 2
chr12_+_21679190 4.024 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr15_-_55652777 4.007 CCPG1
cell cycle progression 1
chr4_+_113970784 3.950 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr1_-_13673510 3.946 NM_001099854
PRAMEF14
PRAME family member 14
chr6_+_29364331 3.942 NM_013936
OR12D2
olfactory receptor, family 12, subfamily D, member 2
chr2_-_200325200 3.926 SATB2
SATB homeobox 2
chr11_+_92085261 3.920 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr5_+_173472737 3.902 HMP19
HMP19 protein
chr4_+_113739203 3.890 NM_001127493
ANK2
ankyrin 2, neuronal
chrX_+_49325433 3.887 NM_001127199
NM_001476
NM_001477
NM_001098409
NM_001098408
NM_001098418
GAGE12D
GAGE1
GAGE4
GAGE5
GAGE6
GAGE7
GAGE12I
GAGE12G
GAGE12C
GAGE12B
GAGE12E
G antigen 12D
G antigen 1
G antigen 4
G antigen 5
G antigen 6
G antigen 7
G antigen 12I
G antigen 12G
G antigen 12C
G antigen 12B
G antigen 12E
chr17_-_66951381 3.885 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_+_118573911 3.883 PEBP1
phosphatidylethanolamine binding protein 1
chr11_+_121163470 3.862 SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
chrX_+_49334991 3.857 NM_001127199
NM_001476
NM_001477
NM_001098409
NM_001098408
NM_001098418
GAGE12D
GAGE1
GAGE4
GAGE5
GAGE6
GAGE7
GAGE12I
GAGE12G
GAGE12C
GAGE12B
GAGE12E
G antigen 12D
G antigen 1
G antigen 4
G antigen 5
G antigen 6
G antigen 7
G antigen 12I
G antigen 12G
G antigen 12C
G antigen 12B
G antigen 12E
chr13_-_45048436 3.854 NM_001243798
TSC22D1
TSC22 domain family, member 1
chr5_+_140165875 3.845 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr4_+_159131400 3.831 NM_018342
TMEM144
transmembrane protein 144
chr5_+_140739589 3.812 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr21_-_27423423 3.774


chrX_+_49235707 3.763 NM_001098411
GAGE2B
G antigen 2B
chr7_+_142829169 3.757 NM_002652
PIP
prolactin-induced protein
chr1_-_11714396 3.731 FBXO2
F-box protein 2
chr12_-_71182699 3.722 NM_001207015
PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_+_140247767 3.709 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chrX_+_114795176 3.700 NM_005032
PLS3
plastin 3
chr4_-_70826712 3.700 NM_001891
CSN2
casein beta
chr22_-_18923963 3.691 NM_001195226
NM_016335
PRODH

proline dehydrogenase (oxidase) 1

chr10_-_62332666 3.680 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_102942968 3.676 NM_001142419
NM_001142420
NM_001142421
NM_001142422
NM_001142427
NM_001142428
NM_001142431
NM_001142432
MORF4L2







mortality factor 4 like 2







chr5_+_140797270 3.661 PCDHGB7
protocadherin gamma subfamily B, 7
chr2_-_217560247 3.628 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr5_-_41261539 3.614 NM_001115131
C6
complement component 6
chr2_+_189839078 3.590 NM_000090
COL3A1
collagen, type III, alpha 1
chr4_-_169401571 3.552 DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr12_+_118573945 3.462 PEBP1
phosphatidylethanolamine binding protein 1
chr6_+_27925018 3.458 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr5_+_140800536 3.456 NM_018914
NM_032091
NM_032092
PCDHGA11


protocadherin gamma subfamily A, 11


chr9_-_41327363 3.442 NM_015667
NM_001242613
NM_001113541
FAM75A7
FAM75A4
FAM75A5
family with sequence similarity 75, member A7
family with sequence similarity 75, member A4
family with sequence similarity 75, member A5
chr12_-_91505541 3.441 NM_002345
LUM
lumican
chr6_-_169654047 3.438 NM_003247
THBS2
thrombospondin 2
chr16_-_21289637 3.430 CRYM
crystallin, mu
chr4_+_41614911 3.412 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr6_-_134639195 3.401 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_48807725 3.367 NM_001198594
STON1
STON1-GTF2A1L
stonin 1
STON1-GTF2A1L readthrough
chr7_-_126883568 3.362 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr2_-_77749335 3.333 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr5_+_175511848 3.330 NM_001079529
FAM153B
family with sequence similarity 153, member B
chrX_+_49306324 3.311 NM_001127199
NM_001098409
NM_001098408
NM_001127345
NM_001098418
NM_001098410
GAGE12D
GAGE6
GAGE7
GAGE12G
GAGE12C
GAGE12B
GAGE12E
GAGE12H
G antigen 12D
G antigen 6
G antigen 7
G antigen 12G
G antigen 12C
G antigen 12B
G antigen 12E
G antigen 12H
chr4_-_176733901 3.303 GPM6A
glycoprotein M6A
chr2_+_26403584 3.289 NM_001191033
FAM59B
family with sequence similarity 59, member B
chr20_-_43883183 3.288 NM_003064
SLPI
secretory leukocyte peptidase inhibitor
chr12_-_71148383 3.282 NM_130846
NM_001207016
PTPRR

protein tyrosine phosphatase, receptor type, R

chrX_+_49344540 3.278 NM_001127199
NM_001098408
NM_001098418
NM_001098410
GAGE12D
GAGE12C
GAGE12B
GAGE12E
GAGE12H
G antigen 12D
G antigen 12C
G antigen 12B
G antigen 12E
G antigen 12H
chr1_-_144997110 3.276 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr6_-_46889620 3.275 NM_001098518
GPR116
G protein-coupled receptor 116
chr1_-_153029987 3.266 NM_005988
SPRR2A
small proline-rich protein 2A
chr16_-_21289571 3.264 CRYM
crystallin, mu
chrX_+_49296768 3.262 NM_001127199
NM_001098409
NM_001098408
NM_001127345
NM_001098418
NM_001098410
GAGE12D
GAGE6
GAGE7
GAGE12G
GAGE12C
GAGE12B
GAGE12E
GAGE12H
G antigen 12D
G antigen 6
G antigen 7
G antigen 12G
G antigen 12C
G antigen 12B
G antigen 12E
G antigen 12H
chr7_+_134464161 3.245 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr7_-_50772997 3.232 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr5_+_31799030 3.219 NM_178140
PDZD2
PDZ domain containing 2
chr5_+_140345746 3.219 NM_018899
PCDHAC2
protocadherin alpha subfamily C, 2
chr1_+_50571963 3.213 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_+_78225068 3.208 NM_014903
NAV3
neuron navigator 3
chr4_+_70861647 3.208 NM_001009181
NM_003154
STATH

statherin

chr1_-_244006471 3.184 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chrX_+_65384078 3.169 NM_001130860
NM_014799
HEPH

hephaestin

chr4_+_70796798 3.139 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr2_-_44586854 3.137 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr10_+_35426709 3.135 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr9_-_90749899 3.129 NM_001166137
FAM75C2
family with sequence similarity 75, member C2
chr9_-_21228132 3.120 NM_021268
IFNA17
interferon, alpha 17
chr5_+_140729723 3.114 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr12_+_7167979 3.106 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr21_-_27543134 3.099 NM_000484
NM_001136129
NM_001136130
NM_001204301
NM_001204302
NM_001204303
NM_201413
NM_201414
APP







amyloid beta (A4) precursor protein







chr12_-_71148331 3.062 PTPRR
protein tyrosine phosphatase, receptor type, R
chr6_+_126240369 3.045 NM_001199622
NCOA7
nuclear receptor coactivator 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.12 5.79e-09 GO:0007156 homophilic cell adhesion
1.68 3.45e-05 GO:0006082 organic acid metabolic process
1.67 6.19e-05 GO:0019752 carboxylic acid metabolic process
1.67 6.19e-05 GO:0043436 oxoacid metabolic process
1.25 9.45e-05 GO:0023052 signaling
1.65 1.13e-04 GO:0042180 cellular ketone metabolic process
2.51 3.58e-04 GO:0006805 xenobiotic metabolic process
2.51 3.58e-04 GO:0071466 cellular response to xenobiotic stimulus
2.49 4.40e-04 GO:0009410 response to xenobiotic stimulus
1.30 2.27e-03 GO:0042221 response to chemical stimulus
1.20 2.40e-03 GO:0051716 cellular response to stimulus
1.55 3.54e-03 GO:0007155 cell adhesion
1.55 3.54e-03 GO:0022610 biological adhesion
1.90 4.07e-03 GO:0016337 cell-cell adhesion
1.23 4.65e-03 GO:0007165 signal transduction
1.30 5.66e-03 GO:0065008 regulation of biological quality
4.02 1.54e-02 GO:0060338 regulation of type I interferon-mediated signaling pathway
1.80 2.22e-02 GO:0032787 monocarboxylic acid metabolic process
1.11 4.80e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.69 3.72e-10 GO:0044421 extracellular region part
1.79 4.93e-10 GO:0005615 extracellular space
1.36 2.52e-06 GO:0044459 plasma membrane part
1.21 7.55e-05 GO:0005886 plasma membrane
1.54 1.14e-04 GO:0005626 insoluble fraction
1.21 1.16e-04 GO:0071944 cell periphery
1.46 1.38e-04 GO:0000267 cell fraction
1.42 1.61e-04 GO:0031226 intrinsic to plasma membrane
1.43 1.76e-04 GO:0005887 integral to plasma membrane
1.52 4.81e-04 GO:0005624 membrane fraction
1.30 8.28e-04 GO:0005576 extracellular region
1.41 2.12e-02 GO:0042995 cell projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.67 1.76e-05 GO:0005509 calcium ion binding
2.01 5.70e-03 GO:0005125 cytokine activity
9.28 1.13e-02 GO:0032052 bile acid binding
1.96 2.75e-02 GO:0005126 cytokine receptor binding
6.96 2.79e-02 GO:0005132 interferon-alpha/beta receptor binding