Motif ID: HMX1.p2

Z-value: 1.053


Transcription factors associated with HMX1.p2:

Gene SymbolEntrez IDGene Name
HMX1 3166 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMX1chr4_-_88734530.363.3e-08Click!


Activity profile for motif HMX1.p2.

activity profile for motif HMX1.p2


Sorted Z-values histogram for motif HMX1.p2

Sorted Z-values for motif HMX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_203499819 17.763 NM_173511
FAM117B
family with sequence similarity 117, member B
chr1_+_151254740 14.978 NM_020832
ZNF687
zinc finger protein 687
chr10_-_99531712 11.138 NM_003015
SFRP5
secreted frizzled-related protein 5
chr18_+_11981457 11.036 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chrX_-_107019001 10.473 NM_198057
TSC22D3
TSC22 domain family, member 3
chr11_+_61129831 9.607 TMEM138
transmembrane protein 138
chr13_-_41495804 9.158 LOC100616668
SUGT1P3
TPTE2 pseudogene
suppressor of G2 allele of SKP1 (S. cerevisiae) pseudogene 3
chr19_+_57752051 9.021 NM_001023563
NM_001145078
ZNF805

zinc finger protein 805

chr17_-_74236272 8.540 NM_052916
RNF157
ring finger protein 157
chr19_+_54058493 8.351 NM_001079907
ZNF331
zinc finger protein 331
chr19_+_54041332 8.202 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chrX_-_107018889 8.135 TSC22D3
TSC22 domain family, member 3
chr13_+_42031525 8.042 NM_014059
C13orf15
chromosome 13 open reading frame 15
chr2_+_27346656 7.905 NM_032604
ABHD1
abhydrolase domain containing 1
chr16_-_86542463 7.796 LOC400550
uncharacterized LOC400550
chr17_+_28256873 7.683 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chr1_-_154193044 7.670 C1orf43
chromosome 1 open reading frame 43
chr13_+_42031690 7.604 C13orf15
chromosome 13 open reading frame 15
chr13_+_42031679 7.576 C13orf15
chromosome 13 open reading frame 15
chr3_-_52312257 7.468 WDR82
WD repeat domain 82
chr7_-_37488554 7.384 NM_014800
ELMO1
engulfment and cell motility 1
chrX_-_13835187 7.370 GPM6B
glycoprotein M6B
chr19_+_54042041 7.316 NM_001253800
ZNF331
zinc finger protein 331
chr3_+_101546833 6.974 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_-_53448167 6.932 LOC283335
uncharacterized LOC283335
chr16_+_2653350 6.902 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr2_-_69870705 6.703 AAK1
AP2 associated kinase 1
chr20_-_590909 6.681 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr2_+_242641310 6.623 NM_032329
ING5
inhibitor of growth family, member 5
chr12_-_49392909 6.486 NM_015086
DDN
dendrin
chr9_-_136024522 6.343 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr2_-_69870837 6.270 AAK1
AP2 associated kinase 1
chr12_-_6798528 5.988 NM_133476
ZNF384
zinc finger protein 384
chr19_+_54057898 5.969 NM_001253801
ZNF331
zinc finger protein 331
chr7_-_37488408 5.968 ELMO1
engulfment and cell motility 1
chr19_+_13875345 5.855 MRI1
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr1_+_145438437 5.850 NM_006472
TXNIP
thioredoxin interacting protein
chr10_-_120514669 5.825 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr17_+_3627133 5.820 NM_031965
GSG2
germ cell associated 2 (haspin)
chr9_+_137967401 5.676 OLFM1
olfactomedin 1
chrX_-_13835012 5.616 GPM6B
glycoprotein M6B
chr5_-_130970851 5.521 RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr3_-_18466759 5.510 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr5_-_130970907 5.257 NM_001164386
NM_001164387
NM_001164388
NM_001164389
NM_001164390
NM_016340
RAPGEF6





Rap guanine nucleotide exchange factor (GEF) 6





chr1_+_201476283 5.247


chr19_-_4535202 5.025 NM_001013706
PLIN5
perilipin 5
chr8_-_143999255 5.007 NM_000498
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr9_+_137967366 4.973 OLFM1
olfactomedin 1
chr4_+_176987148 4.962 WDR17
WD repeat domain 17
chr19_-_57183122 4.958 NM_001005850
ZNF835
zinc finger protein 835
chr19_+_13875352 4.954 MRI1
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr19_+_50796820 4.939 MYH14
myosin, heavy chain 14, non-muscle
chr15_-_76030958 4.905 DNM1P35
DNM1 pseudogene 35
chr15_-_43941037 4.789 NM_054020
NM_172095
NM_172097
CATSPER2


cation channel, sperm associated 2


chr16_-_49315682 4.758 NM_004352
CBLN1
cerebellin 1 precursor
chr22_+_50781773 4.729 PPP6R2
protein phosphatase 6, regulatory subunit 2
chr10_+_126150340 4.724 NM_001167880
NM_022126
LHPP

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

chr16_+_69166538 4.707 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr2_-_101925051 4.702 NM_173647
RNF149
ring finger protein 149
chr14_-_101034261 4.676 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr9_+_137967267 4.637 OLFM1
olfactomedin 1
chr12_+_112451229 4.603


chr5_-_68485278 4.599


chr4_+_176986984 4.585 NM_170710
NM_181265
WDR17

WD repeat domain 17

chrX_-_13835213 4.519 GPM6B
glycoprotein M6B
chr17_-_78450247 4.503 NM_002522
NPTX1
neuronal pentraxin I
chr2_+_61293038 4.498 KIAA1841
KIAA1841
chr8_+_24772454 4.461 NM_001105541
NEFM
neurofilament, medium polypeptide
chr19_-_14952688 4.439 NM_001005190
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr14_+_101300806 4.436 MEG3
maternally expressed 3 (non-protein coding)
chr5_+_148206155 4.411 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr22_-_20104745 4.392 NM_022727
NM_182984
TRMT2A

TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)

chr5_+_56110899 4.378 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr19_-_37019169 4.354 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr21_-_40032563 4.353 NM_001243428
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr17_+_21279667 4.349 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr16_-_70713927 4.331 MTSS1L
metastasis suppressor 1-like
chr14_-_25078818 4.292 NM_033423
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr7_-_752742 4.272 NM_001164761
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_-_6798619 4.266 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chrX_-_78622711 4.230 ITM2A
integral membrane protein 2A
chrX_-_13835313 4.227 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr5_-_58334936 4.172 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr21_+_41239346 4.155 NM_006198
PCP4
Purkinje cell protein 4
chr22_-_20104695 4.148 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr17_-_1619473 4.144 MIR22HG
MIR22 host gene (non-protein coding)
chr2_-_68384575 4.125 NM_138458
WDR92
WD repeat domain 92
chr17_-_34313685 4.082 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr6_+_33043702 4.079 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr19_+_5904842 4.027 NM_001017921
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr4_-_109087876 4.006 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr19_-_10341947 3.997 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr1_+_6052357 3.978 NM_001199861
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_+_156339002 3.953 NM_020407
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr22_-_18923654 3.938 PRODH
proline dehydrogenase (oxidase) 1
chr1_-_177133818 3.928 ASTN1
astrotactin 1
chr12_-_112819755 3.925 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr7_-_97881436 3.901 NM_015395
TECPR1
tectonin beta-propeller repeat containing 1
chr11_-_76155704 3.848


chr16_+_67226027 3.837 NM_001950
E2F4
E2F transcription factor 4, p107/p130-binding
chr12_-_122751044 3.823 NM_022916
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr17_+_41132587 3.800 RUNDC1
RUN domain containing 1
chr19_-_5680910 3.727 NM_205767
C19orf70
chromosome 19 open reading frame 70
chr19_+_47524142 3.722 NM_002517
NPAS1
neuronal PAS domain protein 1
chr19_+_58038744 3.720 ZNF549
zinc finger protein 549
chr18_-_21017816 3.707 NM_032933
TMEM241
transmembrane protein 241
chr16_+_67226098 3.699 E2F4
E2F transcription factor 4, p107/p130-binding
chr2_+_10091791 3.661 NM_198182
GRHL1
grainyhead-like 1 (Drosophila)
chr5_+_156693051 3.658 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr6_-_137113166 3.653


chr12_-_49365545 3.635 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr14_+_92790151 3.615 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr22_+_32149936 3.611 NM_001242897
DEPDC5
DEP domain containing 5
chr12_+_4382882 3.599 NM_001759
CCND2
cyclin D2
chr15_-_65117804 3.593 NM_025049
PIF1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr17_-_62097937 3.575 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr1_+_27719151 3.554 NM_005281
GPR3
G protein-coupled receptor 3
chr2_-_192015934 3.551 NM_003151
STAT4
signal transducer and activator of transcription 4
chr7_-_37488894 3.540 NM_001206480
ELMO1
engulfment and cell motility 1
chr16_+_50186809 3.534 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr1_-_1551041 3.531 MIB2
mindbomb homolog 2 (Drosophila)
chr17_-_28257017 3.529 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr9_-_86571631 3.495 C9orf64
chromosome 9 open reading frame 64
chr11_+_1411089 3.488 NM_003957
BRSK2
BR serine/threonine kinase 2
chr17_+_79651052 3.473


chr2_+_230787195 3.454 NM_174899
FBXO36
F-box protein 36
chr2_-_192015751 3.449 STAT4
signal transducer and activator of transcription 4
chr17_-_8868931 3.417 NM_001142633
NM_001251851
NM_001251852
NM_001251853
NM_001251855
PIK3R5




phosphoinositide-3-kinase, regulatory subunit 5




chr11_+_64692052 3.415 NM_006244
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr7_-_140624280 3.408 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr17_-_39968823 3.401 LEPREL4
leprecan-like 4
chr17_+_72920369 3.392 NM_178160
OTOP2
otopetrin 2
chr2_-_192015706 3.388 STAT4
signal transducer and activator of transcription 4
chr1_-_59042827 3.373 TACSTD2
tumor-associated calcium signal transducer 2
chr2_+_61292999 3.341 NM_001129993
KIAA1841
KIAA1841
chr11_-_45307617 3.326 NM_001247987
NM_020826
SYT13

synaptotagmin XIII

chr9_-_86571533 3.325 C9orf64
chromosome 9 open reading frame 64
chr12_+_53440809 3.321 NM_198316
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_-_192015733 3.317 STAT4
signal transducer and activator of transcription 4
chrX_-_140271275 3.314 LDOC1
leucine zipper, down-regulated in cancer 1
chr7_-_4923246 3.288 NM_018059
RADIL
Ras association and DIL domains
chr15_+_34394273 3.271 NM_152595
PGBD4
piggyBac transposable element derived 4
chr5_-_115910406 3.269 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_+_76156059 3.269 NM_020193
C11orf30
chromosome 11 open reading frame 30
chr9_-_95432542 3.266 NM_022755
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr16_+_69796237 3.261 NM_007014
NM_199423
WWP2

WW domain containing E3 ubiquitin protein ligase 2

chr19_+_57999078 3.257 NM_001098491
NM_001098492
NM_001098493
NM_001098494
NM_001098495
NM_001098496
NM_024691
ZNF419






zinc finger protein 419






chr1_-_9189087 3.255 NM_024980
GPR157
G protein-coupled receptor 157
chr1_+_15573767 3.226 NM_052929
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr15_+_64443909 3.194 NM_024798
SNX22
sorting nexin 22
chr1_+_203444955 3.191 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr3_-_42003460 3.176 NM_017886
ULK4
unc-51-like kinase 4 (C. elegans)
chr1_-_233431458 3.174 NM_014801
PCNXL2
pecanex-like 2 (Drosophila)
chr10_+_11060105 3.174 CELF2
CUGBP, Elav-like family member 2
chr11_-_236833 3.156 SIRT3
sirtuin 3
chr1_-_212588235 3.153 TMEM206
transmembrane protein 206
chr22_+_50781717 3.145 NM_001242898
NM_001242899
NM_001242900
NM_014678
PPP6R2



protein phosphatase 6, regulatory subunit 2



chr1_-_32229635 3.088 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr22_+_40766649 3.083 SGSM3
small G protein signaling modulator 3
chr4_-_8873453 3.079 NM_018942
HMX1
H6 family homeobox 1
chr1_+_36689996 3.076 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr12_-_6798419 3.069 ZNF384
zinc finger protein 384
chr2_-_167232464 3.065 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr22_-_18923963 3.040 NM_001195226
NM_016335
PRODH

proline dehydrogenase (oxidase) 1

chr4_-_8160435 3.036 NM_001130083
NM_001130084
NM_001130085
NM_001130086
NM_001130087
NM_001130088
NM_032432
ABLIM2






actin binding LIM protein family, member 2






chr1_+_36690038 3.009 THRAP3
thyroid hormone receptor associated protein 3
chr20_+_42187705 3.004 SGK2
serum/glucocorticoid regulated kinase 2
chr5_+_74807580 3.001 NM_016218
POLK
polymerase (DNA directed) kappa
chr17_-_27278324 2.995 PHF12
PHD finger protein 12
chr13_-_73356058 2.975 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr6_-_13486382 2.971 NM_001242628
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr16_+_67226070 2.969 E2F4
E2F transcription factor 4, p107/p130-binding
chr16_+_28996369 2.958 NM_001014987
NM_001014988
NM_014387
LAT


linker for activation of T cells


chr3_-_49466744 2.943 NM_032316
NICN1
nicolin 1
chr4_+_88720701 2.941 NM_004967
IBSP
integrin-binding sialoprotein
chr5_+_76326263 2.922 AGGF1
angiogenic factor with G patch and FHA domains 1
chr22_-_31741761 2.920 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr6_-_31763415 2.918 VARS
valyl-tRNA synthetase
chrX_-_140271293 2.913 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr5_+_87564840 2.906 LOC100505894
uncharacterized LOC100505894
chr8_+_26435339 2.898 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr19_+_496453 2.891 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr19_+_13875299 2.877 NM_001031727
NM_032285
MRI1

methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)

chr17_+_78194090 2.869 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr8_+_26371461 2.867 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr17_+_28268622 2.860 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr6_+_41606193 2.859 NM_005586
MDFI
MyoD family inhibitor
chr8_-_143961232 2.859 NM_000497
NM_001026213
CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1

chr6_-_13486986 2.857 GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_-_7973286 2.830 UTS2
urotensin 2
chr6_+_99282579 2.815 NM_005604
POU3F2
POU class 3 homeobox 2
chr2_-_24583291 2.814 NM_006277
NM_019595
NM_147152
ITSN2


intersectin 2


chr2_+_113763448 2.807 NM_014440
IL36A
interleukin 36, alpha
chrX_+_133507299 2.800 NM_001015877
NM_032335
NM_032458
PHF6


PHD finger protein 6


chr10_-_135150368 2.795 CALY
calcyon neuron-specific vesicular protein
chr20_-_44600939 2.794 ZNF335
zinc finger protein 335
chr19_-_7939325 2.787 NM_001190467
FLJ22184
putative uncharacterized protein FLJ22184
chr20_-_35374530 2.764 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr6_-_32095974 2.734 ATF6B
activating transcription factor 6 beta
chr16_+_29985185 2.729 NM_001252043
NM_004783
NM_016151
TAOK2


TAO kinase 2



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 2.18e-14 GO:0065007 biological regulation
1.45 2.72e-14 GO:0023052 signaling
1.25 2.12e-12 GO:0050789 regulation of biological process
1.59 1.19e-11 GO:0030154 cell differentiation
1.43 1.20e-11 GO:0007275 multicellular organismal development
1.15 2.97e-11 GO:0009987 cellular process
1.25 3.21e-11 GO:0050794 regulation of cellular process
1.44 3.59e-11 GO:0048856 anatomical structure development
1.47 4.05e-11 GO:0048731 system development
1.57 5.53e-11 GO:0048869 cellular developmental process
1.39 7.77e-11 GO:0032502 developmental process
1.91 1.02e-10 GO:0050793 regulation of developmental process
1.41 1.91e-10 GO:0007165 signal transduction
2.00 2.81e-10 GO:2000026 regulation of multicellular organismal development
1.67 4.63e-10 GO:0007399 nervous system development
2.29 1.46e-09 GO:0051094 positive regulation of developmental process
1.71 1.48e-09 GO:0051239 regulation of multicellular organismal process
1.57 2.35e-09 GO:0048583 regulation of response to stimulus
1.29 3.24e-09 GO:0032501 multicellular organismal process
1.60 1.09e-08 GO:0023051 regulation of signaling
1.44 1.62e-08 GO:0048518 positive regulation of biological process
1.32 3.87e-08 GO:0051716 cellular response to stimulus
1.45 4.90e-08 GO:0048522 positive regulation of cellular process
1.61 1.17e-07 GO:0009966 regulation of signal transduction
1.52 3.34e-07 GO:0007166 cell surface receptor linked signaling pathway
1.63 5.63e-07 GO:0002376 immune system process
3.60 1.58e-06 GO:0051216 cartilage development
1.48 2.80e-06 GO:0048513 organ development
1.84 4.00e-06 GO:0045595 regulation of cell differentiation
1.53 8.15e-06 GO:0009653 anatomical structure morphogenesis
1.42 1.08e-05 GO:0048523 negative regulation of cellular process
1.40 1.17e-05 GO:0048519 negative regulation of biological process
1.70 1.88e-05 GO:0040011 locomotion
2.05 2.04e-05 GO:0016477 cell migration
2.17 3.45e-05 GO:0045597 positive regulation of cell differentiation
1.67 3.49e-05 GO:0048468 cell development
1.97 4.13e-05 GO:0048870 cell motility
1.97 4.13e-05 GO:0051674 localization of cell
1.30 5.93e-05 GO:0051179 localization
1.65 7.37e-05 GO:0022008 neurogenesis
1.40 7.91e-05 GO:0065008 regulation of biological quality
1.27 1.15e-04 GO:0019222 regulation of metabolic process
1.85 1.20e-04 GO:0006928 cellular component movement
1.19 1.31e-04 GO:0050896 response to stimulus
4.24 1.79e-04 GO:0060560 developmental growth involved in morphogenesis
1.64 2.53e-04 GO:0009888 tissue development
1.73 3.96e-04 GO:0010628 positive regulation of gene expression
1.28 4.91e-04 GO:0060255 regulation of macromolecule metabolic process
2.30 5.59e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.27 9.10e-04 GO:0080090 regulation of primary metabolic process
1.33 1.10e-03 GO:0010468 regulation of gene expression
1.81 1.37e-03 GO:0001775 cell activation
1.70 1.96e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.64 2.16e-03 GO:0006468 protein phosphorylation
1.79 2.49e-03 GO:0043065 positive regulation of apoptosis
2.00 2.77e-03 GO:0051093 negative regulation of developmental process
1.54 2.84e-03 GO:0009892 negative regulation of metabolic process
3.46 2.97e-03 GO:0031294 lymphocyte costimulation
3.46 2.97e-03 GO:0031295 T cell costimulation
2.02 2.99e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.63 3.03e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.77 3.07e-03 GO:0010942 positive regulation of cell death
1.78 3.19e-03 GO:0043068 positive regulation of programmed cell death
1.30 3.50e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 3.74e-03 GO:0031323 regulation of cellular metabolic process
1.91 3.80e-03 GO:0051056 regulation of small GTPase mediated signal transduction
5.95 3.98e-03 GO:0048675 axon extension
1.69 3.99e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.77 4.59e-03 GO:0007417 central nervous system development
1.77 4.76e-03 GO:0000904 cell morphogenesis involved in differentiation
1.44 5.83e-03 GO:0035556 intracellular signal transduction
1.50 5.83e-03 GO:0010646 regulation of cell communication
1.31 5.93e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.81 6.28e-03 GO:0048812 neuron projection morphogenesis
1.56 6.70e-03 GO:0048699 generation of neurons
1.57 6.74e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.81 7.05e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.54 7.32e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.55 7.38e-03 GO:0031324 negative regulation of cellular metabolic process
1.56 8.55e-03 GO:0009891 positive regulation of biosynthetic process
1.82 8.85e-03 GO:0007409 axonogenesis
1.68 9.39e-03 GO:0000902 cell morphogenesis
1.29 1.00e-02 GO:0031326 regulation of cellular biosynthetic process
1.47 1.01e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.50 1.04e-02 GO:0006793 phosphorus metabolic process
1.50 1.04e-02 GO:0006796 phosphate metabolic process
1.28 1.07e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.65 1.08e-02 GO:0030030 cell projection organization
1.30 1.12e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.57 1.18e-02 GO:0048584 positive regulation of response to stimulus
1.61 1.23e-02 GO:0002682 regulation of immune system process
1.76 1.24e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.74 1.24e-02 GO:0031175 neuron projection development
1.28 1.26e-02 GO:0009889 regulation of biosynthetic process
1.40 1.37e-02 GO:0065009 regulation of molecular function
1.44 1.49e-02 GO:0009893 positive regulation of metabolic process
1.88 1.50e-02 GO:0006917 induction of apoptosis
1.80 1.53e-02 GO:0007243 intracellular protein kinase cascade
1.80 1.53e-02 GO:0023014 signal transduction via phosphorylation event
1.87 1.65e-02 GO:0012502 induction of programmed cell death
1.31 1.66e-02 GO:0042221 response to chemical stimulus
1.92 1.72e-02 GO:0060284 regulation of cell development
1.54 1.99e-02 GO:0016310 phosphorylation
2.59 2.37e-02 GO:0035023 regulation of Rho protein signal transduction
2.05 2.39e-02 GO:0040007 growth
1.56 2.46e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.49 2.51e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.66 2.71e-02 GO:0048666 neuron development
1.30 2.73e-02 GO:0051252 regulation of RNA metabolic process
1.88 2.74e-02 GO:0007411 axon guidance
1.69 2.75e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.56 2.98e-02 GO:0006955 immune response
1.67 3.17e-02 GO:0051253 negative regulation of RNA metabolic process
1.31 3.18e-02 GO:0006355 regulation of transcription, DNA-dependent
1.82 3.31e-02 GO:0090066 regulation of anatomical structure size
1.98 3.43e-02 GO:0045596 negative regulation of cell differentiation
4.92 3.54e-02 GO:0048588 developmental cell growth
1.55 3.57e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
8.48 3.59e-02 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
1.59 3.60e-02 GO:0051254 positive regulation of RNA metabolic process
1.61 3.77e-02 GO:0032989 cellular component morphogenesis
1.88 4.10e-02 GO:0001501 skeletal system development
3.46 4.16e-02 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
6.03 4.26e-02 GO:0030513 positive regulation of BMP signaling pathway
1.69 4.38e-02 GO:0048858 cell projection morphogenesis
2.36 4.58e-02 GO:0050870 positive regulation of T cell activation
2.00 4.59e-02 GO:0000165 MAPKKK cascade
1.57 4.64e-02 GO:0009790 embryo development
2.40 4.65e-02 GO:0001503 ossification
1.47 4.68e-02 GO:0009605 response to external stimulus
1.62 4.78e-02 GO:0010629 negative regulation of gene expression
1.59 4.92e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.83 4.92e-02 GO:0042063 gliogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.54 6.63e-12 GO:0044459 plasma membrane part
1.64 1.99e-08 GO:0005887 integral to plasma membrane
1.62 4.87e-08 GO:0031226 intrinsic to plasma membrane
1.26 8.21e-06 GO:0005886 plasma membrane
1.26 9.34e-06 GO:0071944 cell periphery
1.80 1.92e-03 GO:0043005 neuron projection
2.18 4.46e-03 GO:0030424 axon
1.41 2.33e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 5.34e-12 GO:0005488 binding
1.19 1.18e-07 GO:0005515 protein binding
1.51 1.27e-03 GO:0005102 receptor binding
2.35 2.21e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.73 4.09e-03 GO:0030695 GTPase regulator activity
2.73 7.77e-03 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.69 1.01e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.93 1.08e-02 GO:0005261 cation channel activity
1.47 1.08e-02 GO:0030234 enzyme regulator activity
1.70 1.60e-02 GO:0004674 protein serine/threonine kinase activity
1.44 2.64e-02 GO:0001071 nucleic acid binding transcription factor activity
1.44 2.64e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.79 3.63e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
11.30 4.42e-02 GO:0035014 phosphatidylinositol 3-kinase regulator activity