Motif ID: HMX1.p2

Z-value: 1.053


Transcription factors associated with HMX1.p2:

Gene SymbolEntrez IDGene Name
HMX1 3166 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMX1chr4_-_88734530.363.3e-08Click!


Activity profile for motif HMX1.p2.

activity profile for motif HMX1.p2


Sorted Z-values histogram for motif HMX1.p2

Sorted Z-values for motif HMX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_203499819 17.763 NM_173511
 FAM117B
family with sequence similarity 117, member B
chr1_+_151254740 14.978 NM_020832
 ZNF687
zinc finger protein 687
chr10_-_99531712 11.138 NM_003015
 SFRP5
secreted frizzled-related protein 5
chr18_+_11981457 11.036 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chrX_-_107019001 10.473 NM_198057
 TSC22D3
TSC22 domain family, member 3
chr11_+_61129831 9.607 TMEM138
transmembrane protein 138
chr13_-_41495804 9.158 LOC100616668
SUGT1P3
TPTE2 pseudogene
suppressor of G2 allele of SKP1 (S. cerevisiae) pseudogene 3
chr19_+_57752051 9.021 NM_001023563
NM_001145078
 ZNF805

zinc finger protein 805

chr17_-_74236272 8.540 NM_052916
 RNF157
ring finger protein 157
chr19_+_54058493 8.351 NM_001079907
 ZNF331
zinc finger protein 331
chr19_+_54041332 8.202 NM_001079906
NM_001253798
NM_001253799
 ZNF331


zinc finger protein 331


chrX_-_107018889 8.135 TSC22D3
TSC22 domain family, member 3
chr13_+_42031525 8.042 NM_014059
 C13orf15
chromosome 13 open reading frame 15
chr2_+_27346656 7.905 NM_032604
 ABHD1
abhydrolase domain containing 1
chr16_-_86542463 7.796 LOC400550
uncharacterized LOC400550
chr17_+_28256873 7.683 NM_001145053
 EFCAB5
EF-hand calcium binding domain 5
chr1_-_154193044 7.670 C1orf43
chromosome 1 open reading frame 43
chr13_+_42031690 7.604 C13orf15
chromosome 13 open reading frame 15
chr13_+_42031679 7.576 C13orf15
chromosome 13 open reading frame 15
chr3_-_52312257 7.468 WDR82
WD repeat domain 82

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 133 entries
enrichment   p-value GO term description
8.48 3.59e-02 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
6.03 4.26e-02 GO:0030513 positive regulation of BMP signaling pathway
5.95 3.98e-03 GO:0048675 axon extension
4.92 3.54e-02 GO:0048588 developmental cell growth
4.24 1.79e-04 GO:0060560 developmental growth involved in morphogenesis
3.60 1.58e-06 GO:0051216 cartilage development
3.46 2.97e-03 GO:0031294 lymphocyte costimulation
3.46 2.97e-03 GO:0031295 T cell costimulation
3.46 4.16e-02 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.83 4.92e-02 GO:0042063 gliogenesis
2.59 2.37e-02 GO:0035023 regulation of Rho protein signal transduction
2.40 4.65e-02 GO:0001503 ossification
2.36 4.58e-02 GO:0050870 positive regulation of T cell activation
2.30 5.59e-04 GO:0048011 nerve growth factor receptor signaling pathway
2.29 1.46e-09 GO:0051094 positive regulation of developmental process
2.17 3.45e-05 GO:0045597 positive regulation of cell differentiation
2.05 2.04e-05 GO:0016477 cell migration
2.05 2.39e-02 GO:0040007 growth
2.02 2.99e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.00 2.81e-10 GO:2000026 regulation of multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.18 4.46e-03 GO:0030424 axon
1.80 1.92e-03 GO:0043005 neuron projection
1.64 1.99e-08 GO:0005887 integral to plasma membrane
1.62 4.87e-08 GO:0031226 intrinsic to plasma membrane
1.54 6.63e-12 GO:0044459 plasma membrane part
1.41 2.33e-02 GO:0044421 extracellular region part
1.26 8.21e-06 GO:0005886 plasma membrane
1.26 9.34e-06 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
11.30 4.42e-02 GO:0035014 phosphatidylinositol 3-kinase regulator activity
2.79 3.63e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
2.73 7.77e-03 GO:0005088 Ras guanyl-nucleotide exchange factor activity
2.35 2.21e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.93 1.08e-02 GO:0005261 cation channel activity
1.73 4.09e-03 GO:0030695 GTPase regulator activity
1.70 1.60e-02 GO:0004674 protein serine/threonine kinase activity
1.69 1.01e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.51 1.27e-03 GO:0005102 receptor binding
1.47 1.08e-02 GO:0030234 enzyme regulator activity
1.44 2.64e-02 GO:0001071 nucleic acid binding transcription factor activity
1.44 2.64e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.19 1.18e-07 GO:0005515 protein binding
1.13 5.34e-12 GO:0005488 binding