Motif ID: HOXA9_MEIS1.p2

Z-value: 0.751


Transcription factors associated with HOXA9_MEIS1.p2:

Gene SymbolEntrez IDGene Name
HOXA9 3205 homeobox A9
MEIS1 4211 Meis homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA9chr7_-_27205148-0.111.2e-01Click!
MEIS1chr2_+_66662516,
chr2_+_66662692
0.054.6e-01Click!


Activity profile for motif HOXA9_MEIS1.p2.

activity profile for motif HOXA9_MEIS1.p2


Sorted Z-values histogram for motif HOXA9_MEIS1.p2

Sorted Z-values for motif HOXA9_MEIS1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA9_MEIS1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_198608216 23.259 PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_-_24936177 14.569 FAM65B
family with sequence similarity 65, member B
chr2_+_68592317 14.092 NM_002664
PLEK
pleckstrin
chr1_+_198608244 13.150 PTPRC
protein tyrosine phosphatase, receptor type, C
chr17_-_29641068 12.792 EVI2B
ecotropic viral integration site 2B
chr19_+_10828763 12.669 DNM2
dynamin 2
chr12_-_10562744 12.257 NM_001199805
KLRC4-KLRK1
KLRC4-KLRK1 readthrough
chr19_+_10828813 12.009 DNM2
dynamin 2
chr19_+_10828725 11.471 NM_001005360
NM_001005361
NM_001005362
NM_001190716
NM_004945
DNM2




dynamin 2




chr19_+_10828772 10.841 DNM2
dynamin 2
chr14_-_94856926 10.672 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr1_+_198608136 10.390 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr12_-_109027654 10.005 NM_003006
SELPLG
selectin P ligand
chr12_-_9268513 9.067 A2M
alpha-2-macroglobulin
chr17_-_29641094 7.957 NM_006495
EVI2B
ecotropic viral integration site 2B
chr12_-_109027615 7.261 SELPLG
selectin P ligand
chr4_-_166034003 7.148 NM_001100389
TMEM192
transmembrane protein 192
chr10_+_70847817 7.142 NM_002727
SRGN
serglycin
chr18_+_2655885 6.508 NM_015295
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr2_+_68592432 6.053 PLEK
pleckstrin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.78 2.67e-04 GO:0050776 regulation of immune response
2.96 1.40e-03 GO:0002682 regulation of immune system process
2.64 6.64e-03 GO:0006952 defense response
2.63 1.63e-02 GO:0006955 immune response
2.45 4.45e-04 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
33.36 9.54e-03 GO:0005579 membrane attack complex
2.37 8.55e-03 GO:0005626 insoluble fraction
1.95 4.25e-02 GO:0005887 integral to plasma membrane
1.76 7.52e-03 GO:0044459 plasma membrane part
1.54 1.57e-03 GO:0005886 plasma membrane
1.52 2.69e-03 GO:0071944 cell periphery

Nothing significant found in function category.