Motif ID: IKZF1.p2

Z-value: 1.334


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF1chr7_+_50344255-0.393.4e-09Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_74728963 12.631 MBP
myelin basic protein
chr18_-_74729049 12.598 NM_001025081
NM_001025090
NM_001025092
NM_002385
 MBP



myelin basic protein



chr9_-_21994379 11.795 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr17_-_56618178 11.786 NM_001198713
 SEPT4
septin 4
chr9_-_21994414 11.107 NM_058195
 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr3_-_149688638 9.586 NM_002628
NM_053024
 PFN2

profilin 2

chr16_+_29690464 9.036 QPRT
quinolinate phosphoribosyltransferase
chr4_-_176733413 8.984 GPM6A
glycoprotein M6A
chr2_+_17721806 8.950 NM_003385
 VSNL1
visinin-like 1
chr9_-_21994329 8.949 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr19_-_10697907 8.807 NM_005498
 AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr16_+_56659679 8.680 MT1E
metallothionein 1E
chr16_+_56659584 8.547 NM_175617
 MT1E
metallothionein 1E
chr2_+_17721983 8.446 VSNL1
visinin-like 1
chr4_-_176734181 8.337 NM_201591
 GPM6A
glycoprotein M6A
chr1_+_6845381 7.592 NM_001195563
NM_001242701
NM_015215
 CAMTA1


calmodulin binding transcription activator 1


chr4_-_176733901 7.415 GPM6A
glycoprotein M6A
chr16_+_23690234 7.136 PLK1
polo-like kinase 1
chr8_+_145065366 7.101 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr15_+_41136178 7.014 NM_003710
NM_181642
 SPINT1

serine peptidase inhibitor, Kunitz type 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 73 entries
enrichment   p-value GO term description
2.52 1.14e-02 GO:0031570 DNA integrity checkpoint
2.49 3.07e-02 GO:0000077 DNA damage checkpoint
2.39 1.18e-02 GO:0007005 mitochondrion organization
2.04 2.47e-02 GO:0000075 cell cycle checkpoint
2.01 2.80e-02 GO:0071156 regulation of cell cycle arrest
1.78 4.23e-03 GO:0007268 synaptic transmission
1.77 1.45e-03 GO:0019226 transmission of nerve impulse
1.77 1.45e-03 GO:0035637 multicellular organismal signaling
1.76 3.74e-03 GO:0050801 ion homeostasis
1.75 1.18e-02 GO:0006873 cellular ion homeostasis
1.74 1.05e-02 GO:0055082 cellular chemical homeostasis
1.70 2.49e-05 GO:0007267 cell-cell signaling
1.70 8.18e-03 GO:0032990 cell part morphogenesis
1.67 4.06e-04 GO:0043085 positive regulation of catalytic activity
1.67 2.12e-02 GO:0048858 cell projection morphogenesis
1.67 2.29e-02 GO:0044283 small molecule biosynthetic process
1.65 8.25e-05 GO:0044093 positive regulation of molecular function
1.63 1.26e-02 GO:0006259 DNA metabolic process
1.63 3.50e-02 GO:0019725 cellular homeostasis
1.61 2.58e-09 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
2.09 7.54e-03 GO:0044297 cell body
2.09 9.66e-03 GO:0043025 neuronal cell body
1.96 4.84e-02 GO:0030424 axon
1.95 3.71e-02 GO:0030425 dendrite
1.78 1.16e-03 GO:0043005 neuron projection
1.76 2.60e-02 GO:0044456 synapse part
1.74 3.23e-02 GO:0005743 mitochondrial inner membrane
1.70 7.01e-03 GO:0045202 synapse
1.69 3.03e-03 GO:0005740 mitochondrial envelope
1.69 4.51e-02 GO:0019866 organelle inner membrane
1.67 8.17e-03 GO:0031966 mitochondrial membrane
1.61 4.35e-04 GO:0044429 mitochondrial part
1.56 9.59e-03 GO:0030054 cell junction
1.50 1.53e-03 GO:0042995 cell projection
1.42 7.17e-08 GO:0044459 plasma membrane part
1.42 3.89e-04 GO:0005739 mitochondrion
1.40 9.06e-03 GO:0000267 cell fraction
1.37 1.09e-02 GO:0031226 intrinsic to plasma membrane
1.34 4.24e-02 GO:0005887 integral to plasma membrane
1.27 5.06e-03 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.72 3.31e-02 GO:0005200 structural constituent of cytoskeleton
1.52 6.31e-03 GO:0019899 enzyme binding
1.50 2.04e-02 GO:0016491 oxidoreductase activity
1.25 3.87e-15 GO:0005515 protein binding
1.12 3.31e-10 GO:0005488 binding