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Motif ID: IKZF2.p2

Z-value: 1.389

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_80523376	34.000		STMN2	stathmin-like 2
chr11_-_62472901	25.514
chr1_+_155853546	24.916		SYT11	synaptotagmin XI
chr3_-_195310985	24.246	NM_001647	APOD	apolipoprotein D
chr18_-_74728963	22.298		MBP	myelin basic protein
chr18_-_74729049	22.076	NM_001025081 NM_001025090 NM_001025092 NM_002385	MBP	myelin basic protein
chr4_-_176734181	21.662	NM_201591	GPM6A	glycoprotein M6A
chr7_+_86273219	21.458	NM_000840	GRM3	glutamate receptor, metabotropic 3
chr5_-_42811959	21.057	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chrX_+_103031433	20.696	NM_001128834	PLP1	proteolipid protein 1
chrX_+_103031797	20.470		PLP1	proteolipid protein 1
chr1_-_93399531	20.233
chr3_-_195310770	20.078		APOD	apolipoprotein D
chr3_-_58563070	19.754		FAM107A	family with sequence similarity 107, member A
chrX_+_103031753	19.683	NM_000533 NM_199478	PLP1	proteolipid protein 1
chr4_-_153303663	19.424	NM_001013415	FBXW7	F-box and WD repeat domain containing 7
chrX_+_73164162	18.497		JPX	JPX transcript, XIST activator (non-protein coding)
chr7_-_64023444	17.920
chr5_-_146460991	17.574	NM_181677 NM_181678	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr7_-_137028275	17.511		PTN	pleiotrophin
chr9_-_93405066	17.216	NM_017594	DIRAS2	DIRAS family, GTP-binding RAS-like 2
chr3_-_58563490	16.601	NM_001076778 NM_007177	FAM107A	family with sequence similarity 107, member A
chr4_-_176923572	16.300	NM_005277 NM_201592	GPM6A	glycoprotein M6A
chr7_-_137028433	16.224		PTN	pleiotrophin
chr17_-_29624249	16.211	NM_002544	OMG	oligodendrocyte myelin glycoprotein
chr7_-_137028533	15.955	NM_002825	PTN	pleiotrophin
chr11_+_62475165	15.697		GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr2_-_175712276	14.899	NM_001206602	CHN1	chimerin (chimaerin) 1
chr22_-_38380538	14.144	NM_006941	SOX10	SRY (sex determining region Y)-box 10
chr7_-_137028370	14.093		PTN	pleiotrophin
chr15_+_32933869	13.861	NM_001144757 NM_003020	SCG5	secretogranin V (7B2 protein)
chr6_+_158733691	13.704	NM_001007466 NM_020245	TULP4	tubby like protein 4
chr1_-_57045235	13.489	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr7_+_64498643	13.418		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr4_+_88896868	13.186		SPP1	secreted phosphoprotein 1
chr4_-_153273683	13.117	NM_018315	FBXW7	F-box and WD repeat domain containing 7
chr17_-_66951381	12.656	NM_007168	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr8_+_24771276	12.500		NEFM	neurofilament, medium polypeptide
chr18_-_53089722	12.492	NM_001243233	TCF4	transcription factor 4
chr18_-_53071225	12.436	NM_001243232	TCF4	transcription factor 4
chr15_+_25101697	12.187	NM_022805	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr1_-_57045214	11.812		PPAP2B	phosphatidic acid phosphatase type 2B
chr5_+_161274196	11.540	NM_000806	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_-_163113938	11.484		RGS5	regulator of G-protein signaling 5
chr4_+_154125589	11.462	NM_015271	TRIM2	tripartite motif containing 2
chr8_-_18541441	11.337		PSD3	pleckstrin and Sec7 domain containing 3
chrX_+_135251454	11.200	NM_001159704	FHL1	four and a half LIM domains 1
chr4_+_88896838	10.902		SPP1	secreted phosphoprotein 1
chr7_+_153584383	10.851	NM_001039350	DPP6	dipeptidyl-peptidase 6
chr11_+_62475113	10.830	NM_012202	GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr7_-_99680358	10.820		ZNF3	zinc finger protein 3
chr4_+_113739203	10.790	NM_001127493	ANK2	ankyrin 2, neuronal
chr5_+_173472692	10.754	NM_015980	HMP19	HMP19 protein
chr15_+_43885251	10.751	NM_020990	CKMT1B CKMT1A	creatine kinase, mitochondrial 1B creatine kinase, mitochondrial 1A
chr8_+_85095702	10.697		RALYL	RALY RNA binding protein-like
chr8_+_24771268	10.461	NM_005382	NEFM	neurofilament, medium polypeptide
chr8_+_80523351	10.368		STMN2	stathmin-like 2
chr4_+_88896899	10.261		SPP1	secreted phosphoprotein 1
chr3_-_42305438	10.078	NM_001174138	CCK	cholecystokinin
chr3_+_112051914	10.045	NM_001004196 NM_005944	CD200	CD200 molecule
chr10_+_105036783	9.747	NM_032727	INA	internexin neuronal intermediate filament protein, alpha
chr1_-_170038055	9.684	NM_001204517	KIFAP3	kinesin-associated protein 3
chr8_+_80523048	9.669	NM_001199214 NM_007029	STMN2	stathmin-like 2
chr4_-_87281177	9.613		MAPK10	mitogen-activated protein kinase 10
chr20_+_5891973	9.547	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr22_-_38379868	9.404		SOX10	SRY (sex determining region Y)-box 10
chr11_-_65382701	9.266		MAP3K11	mitogen-activated protein kinase kinase kinase 11
chr16_+_81272293	9.229	NM_017429	BCMO1	beta-carotene 15,15'-monooxygenase 1
chr1_+_163038934	9.073	NM_001113381	RGS4	regulator of G-protein signaling 4
chr5_-_151066445	9.070		SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr1_+_163038564	9.046	NM_005613	RGS4	regulator of G-protein signaling 4
chr12_-_16759733	9.035	NM_001243610	LMO3	LIM domain only 3 (rhombotin-like 2)
chr8_+_80523339	8.986		STMN2	stathmin-like 2
chr19_+_54926721	8.923		TTYH1	tweety homolog 1 (Drosophila)
chr14_-_21270537	8.890	NM_198232	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)
chr6_+_123100645	8.817	NM_001446	FABP7	fatty acid binding protein 7, brain
chr1_+_159175048	8.816	NM_001122951	DARC	Duffy blood group, chemokine receptor
chr5_-_138211054	8.732	NM_015564	LRRTM2	leucine rich repeat transmembrane neuronal 2
chr8_+_121457642	8.556	NM_022045	MTBP	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr4_-_87281374	8.498	NM_138980 NM_138982	MAPK10	mitogen-activated protein kinase 10
chr3_+_238274	8.458	NM_001253387 NM_006614	CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr8_+_26435920	8.452	NM_001244604	DPYSL2	dihydropyrimidinase-like 2
chr8_-_82359620	8.425	NM_002677	PMP2	peripheral myelin protein 2
chr12_-_16760935	8.412	NM_001001395 NM_001243609	LMO3	LIM domain only 3 (rhombotin-like 2)
chr11_+_126152979	8.340	NM_001039661 NM_148910	TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr2_-_127963342	8.318	NM_001001665	CYP27C1	cytochrome P450, family 27, subfamily C, polypeptide 1
chr8_-_22089517	8.210		PHYHIP	phytanoyl-CoA 2-hydroxylase interacting protein
chr8_-_110655418	8.163	NM_001099756	SYBU	syntabulin (syntaxin-interacting)
chr1_+_50569581	8.147	NM_001144776	ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_+_100531764	8.126		EVL	Enah/Vasp-like
chr3_-_18480203	8.078	NM_001131010	SATB1	SATB homeobox 1
chrX_+_100333835	8.072	NM_021637	TMEM35	transmembrane protein 35
chr12_-_91573264	8.065	NM_133503	DCN	decorin
chr8_-_27101240	8.063		STMN4	stathmin-like 4
chr18_-_21852189	8.050	NM_018030	OSBPL1A	oxysterol binding protein-like 1A
chr4_+_88896801	8.008	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr3_+_361365	7.995	NM_001253388	CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr14_+_100531745	7.915	NM_016337	EVL	Enah/Vasp-like
chr5_-_43412417	7.870	NM_148672	CCL28	chemokine (C-C motif) ligand 28
chrX_+_102632108	7.818	NM_014380	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_-_16759430	7.810		LMO3	LIM domain only 3 (rhombotin-like 2)
chr3_+_115342302	7.784		GAP43	growth associated protein 43
chr2_+_189839113	7.782		COL3A1	collagen, type III, alpha 1
chr5_-_88179278	7.774	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr18_-_21017816	7.771	NM_032933	TMEM241	transmembrane protein 241
chrX_+_134866213	7.763	NM_001017436 NM_152582	CT45A3 CT45A4 CT45A2	cancer/testis antigen family 45, member A3 cancer/testis antigen family 45, member A4 cancer/testis antigen family 45, member A2
chr2_-_175869910	7.762	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr1_+_84647342	7.738	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr3_+_115342150	7.727	NM_001130064 NM_002045	GAP43	growth associated protein 43
chr2_+_17935124	7.494	NM_182625	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr2_+_189839132	7.442		COL3A1	collagen, type III, alpha 1
chr19_+_54926604	7.395	NM_001005367 NM_001201461 NM_020659	TTYH1	tweety homolog 1 (Drosophila)
chr18_-_53068755	7.333		TCF4	transcription factor 4
chr1_-_230850335	7.318	NM_000029	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr12_+_101988746	7.251	NM_002465 NM_206819 NM_206820 NM_206821	MYBPC1	myosin binding protein C, slow type
chr1_+_152850797	7.081	NM_030663	SMCP	sperm mitochondria-associated cysteine-rich protein
chr8_+_1952875	7.079		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr8_-_37727937	6.992		RAB11FIP1	RAB11 family interacting protein 1 (class I)
chrX_+_110366304	6.919	NM_001128168 NM_001128172 NM_001128173	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr9_-_79520878	6.917	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr5_+_140247767	6.910	NM_018902 NM_031861	PCDHA11	protocadherin alpha 11
chr2_+_189839078	6.877	NM_000090	COL3A1	collagen, type III, alpha 1
chr18_-_40695483	6.823	NM_002930	RIT2	Ras-like without CAAX 2
chr15_+_43985083	6.808	NM_001015001	CKMT1A	creatine kinase, mitochondrial 1A
chr10_+_111765725	6.772	NM_019903	ADD3	adducin 3 (gamma)
chr20_-_23402038	6.728	NM_022080	NAPB	N-ethylmaleimide-sensitive factor attachment protein, beta
chr5_+_173472737	6.709		HMP19	HMP19 protein
chr9_-_91793375	6.648		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr18_-_52988916	6.643	NM_001243234 NM_001243235	TCF4	transcription factor 4
chr8_+_11141983	6.636	NM_015458	MTMR9	myotubularin related protein 9
chr6_+_27107060	6.586	NM_003495	HIST2H4B HIST1H4I	histone cluster 2, H4b histone cluster 1, H4i
chr12_-_16759531	6.545	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr16_+_7382750	6.538	NM_145891 NM_145892 NM_145893	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_71587674	6.538	NM_001037442 NM_014961	RUFY3	RUN and FYVE domain containing 3
chr13_+_97794050	6.482		MBNL2	muscleblind-like 2 (Drosophila)
chr7_+_94024201	6.472		COL1A2	collagen, type I, alpha 2
chr2_+_207406815	6.469		ADAM23	ADAM metallopeptidase domain 23
chr12_-_16759939	6.448	NM_001243613	LMO3	LIM domain only 3 (rhombotin-like 2)
chr5_-_108745569	6.427	NM_014819	PJA2	praja ring finger 2
chr13_+_58205943	6.399		PCDH17	protocadherin 17
chrX_+_135251795	6.378	NM_001167819	FHL1	four and a half LIM domains 1
chr1_-_57045129	6.369		PPAP2B	phosphatidic acid phosphatase type 2B
chr5_-_146435589	6.313	NM_181674 NM_181676	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr18_-_53303129	6.231	NM_001243226	TCF4	transcription factor 4
chr10_-_79789290	6.199	NM_007055	POLR3A	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chrX_-_6145887	6.179	NM_020742	NLGN4X	neuroligin 4, X-linked
chr13_+_42846255	6.172	NM_016248	AKAP11	A kinase (PRKA) anchor protein 11
chr7_+_138482696	6.152	NM_001085429	TMEM213	transmembrane protein 213
chr4_+_113970784	6.133	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr8_+_80523304	6.133		STMN2	stathmin-like 2
chr3_+_10068123	6.131		FANCD2	Fanconi anemia, complementation group D2
chr19_+_38893828	6.131		FAM98C	family with sequence similarity 98, member C
chr2_-_2334887	6.106	NM_015025	MYT1L	myelin transcription factor 1-like
chr12_+_175872	6.096	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr12_-_91576579	6.072		DCN	decorin
chr6_-_46825942	6.072		GPR116	G protein-coupled receptor 116
chr6_+_121756744	6.069	NM_000165	GJA1	gap junction protein, alpha 1, 43kDa
chr11_-_62475060	6.051	NM_001122955	BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_+_140771482	6.039	NM_014004 NM_032088	PCDHGA8	protocadherin gamma subfamily A, 8
chr3_+_112052020	6.021		CD200	CD200 molecule
chrX_+_135230736	6.018	NM_001159700	FHL1	four and a half LIM domains 1
chr19_-_12662191	5.989	NM_144976	ZNF564	zinc finger protein 564
chrX_-_63005212	5.986	NM_001173479	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chrX_+_100805415	5.976	NM_016608	ARMCX1	armadillo repeat containing, X-linked 1
chr18_-_21891469	5.925	NM_001242508	OSBPL1A	oxysterol binding protein-like 1A
chr7_+_142560512	5.923		EPHB6	EPH receptor B6
chr11_-_33890931	5.922		LMO2	LIM domain only 2 (rhombotin-like 1)
chr12_-_133532847	5.912	NM_183238 NM_001164715	ZNF605	zinc finger protein 605
chr12_-_15038724	5.892	NM_000900 NM_001190839	MGP	matrix Gla protein
chr3_+_101546833	5.861	NM_001005474	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr7_+_123565908	5.858	NM_001174045 NM_001174046	SPAM1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
chr1_-_57044980	5.825		PPAP2B	phosphatidic acid phosphatase type 2B
chr12_+_79439432	5.793	NM_001135806	SYT1	synaptotagmin I
chr3_+_10068097	5.688	NM_001018115 NM_033084	FANCD2	Fanconi anemia, complementation group D2
chr16_+_10522724	5.688	NM_024997	ATF7IP2	activating transcription factor 7 interacting protein 2
chr7_-_14880954	5.677	NM_004080 NM_145695	DGKB	diacylglycerol kinase, beta 90kDa
chr1_+_50571963	5.670	NM_001144775	ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_-_111782447	5.641	NM_001885	CRYAB	crystallin, alpha B
chr5_-_88199868	5.614	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr4_+_176987148	5.600		WDR17	WD repeat domain 17
chrX_+_133507299	5.575	NM_001015877 NM_032335 NM_032458	PHF6	PHD finger protein 6
chr14_+_23299083	5.558	NM_178336 NM_180982 NM_181304 NM_181305 NM_181306 NM_181307	MRPL52	mitochondrial ribosomal protein L52
chr4_+_106631966	5.453	NM_001031720	GSTCD	glutathione S-transferase, C-terminal domain containing
chr13_-_73356070	5.445	NM_001128226 NM_014953	DIS3	DIS3 mitotic control homolog (S. cerevisiae)
chrX_-_102941582	5.430	NM_001142418 NM_001142423 NM_001142424 NM_001142425 NM_001142426 NM_001142429 NM_001142430 NM_012286	MORF4L2	mortality factor 4 like 2
chr8_-_102803438	5.348	NM_032041	NCALD	neurocalcin delta
chr1_+_168148215	5.341		TIPRL	TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr4_-_174320616	5.337	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr8_+_39442086	5.326	NM_001190956 NM_014237	ADAM18	ADAM metallopeptidase domain 18
chr19_+_41509825	5.259		CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chrX_+_135278912	5.225	NM_001159701 NM_001159699	FHL1	four and a half LIM domains 1
chr2_-_238322815	5.219		COL6A3	collagen, type VI, alpha 3
chr1_-_203320249	5.218
chr12_-_45269340	5.217	NM_001145109	NELL2	NEL-like 2 (chicken)
chr1_+_84630014	5.200	NM_001242857 NM_001242858 NM_001242859	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chrX_+_38420690	5.194	NM_004615	TSPAN7	tetraspanin 7
chr9_+_102677457	5.165		STX17	syntaxin 17
chr2_-_238322770	5.150		COL6A3	collagen, type VI, alpha 3
chr3_-_9290592	5.149		SRGAP3	SLIT-ROBO Rho GTPase activating protein 3
chr19_+_21264952	5.139	NM_182515	ZNF714	zinc finger protein 714

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.88	5.34e-09	GO:0007155	cell adhesion
1.88	5.34e-09	GO:0022610	biological adhesion
1.31	3.76e-07	GO:0023052	signaling
1.72	8.88e-07	GO:0040011	locomotion
1.17	1.09e-06	GO:0065007	biological regulation
1.18	2.30e-06	GO:0050789	regulation of biological process
1.18	2.42e-06	GO:0050794	regulation of cellular process
1.20	3.45e-06	GO:0050896	response to stimulus
1.27	3.76e-06	GO:0051716	cellular response to stimulus
1.30	6.27e-06	GO:0007165	signal transduction
1.44	8.68e-06	GO:0007166	cell surface receptor linked signaling pathway
1.65	1.05e-05	GO:0009611	response to wounding
1.22	1.49e-05	GO:0032501	multicellular organismal process
1.10	2.42e-05	GO:0009987	cellular process
1.53	2.59e-05	GO:0002376	immune system process
1.89	3.29e-04	GO:0016477	cell migration
1.29	8.72e-04	GO:0048731	system development
1.35	1.16e-03	GO:0030154	cell differentiation
1.31	1.17e-03	GO:0006950	response to stress
1.79	1.55e-03	GO:0048870	cell motility
1.79	1.55e-03	GO:0051674	localization of cell
1.80	1.80e-03	GO:0050776	regulation of immune response
1.33	2.21e-03	GO:0048869	cellular developmental process
1.70	2.76e-03	GO:0006928	cellular component movement
1.61	3.04e-03	GO:0002682	regulation of immune system process
1.40	4.30e-03	GO:0007399	nervous system development
1.65	5.79e-03	GO:0042060	wound healing
1.55	1.01e-02	GO:0006955	immune response
1.33	1.01e-02	GO:0048583	regulation of response to stimulus
1.69	1.20e-02	GO:0007596	blood coagulation
1.69	1.20e-02	GO:0050817	coagulation
2.29	1.28e-02	GO:0050900	leukocyte migration
1.67	1.44e-02	GO:0006935	chemotaxis
1.67	1.44e-02	GO:0042330	taxis
1.49	1.49e-02	GO:0022008	neurogenesis
1.68	1.54e-02	GO:0007599	hemostasis
1.24	1.58e-02	GO:0048856	anatomical structure development
2.35	1.96e-02	GO:0007156	homophilic cell adhesion
1.71	2.00e-02	GO:0002684	positive regulation of immune system process
1.50	2.84e-02	GO:0006952	defense response
1.28	3.78e-02	GO:0042221	response to chemical stimulus
1.65	3.95e-02	GO:0019226	transmission of nerve impulse
1.65	3.95e-02	GO:0035637	multicellular organismal signaling
1.84	4.56e-02	GO:0016337	cell-cell adhesion

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.40	4.77e-07	GO:0044459	plasma membrane part
1.51	5.63e-06	GO:0031226	intrinsic to plasma membrane
1.51	6.94e-06	GO:0005887	integral to plasma membrane
1.52	7.15e-05	GO:0044421	extracellular region part
1.56	4.08e-04	GO:0005615	extracellular space
1.32	4.28e-04	GO:0005576	extracellular region
1.21	5.73e-04	GO:0005886	plasma membrane
1.20	9.64e-04	GO:0071944	cell periphery
1.71	3.79e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.12	8.17e-03	GO:0005515	protein binding
7.70	1.45e-02	GO:0005132	interferon-alpha/beta receptor binding
1.06	2.11e-02	GO:0005488	binding
5.14	3.64e-02	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity