Motif ID: IKZF2.p2

Z-value: 1.389


Transcription factors associated with IKZF2.p2:

Gene SymbolEntrez IDGene Name
IKZF2 22807 IKAROS family zinc finger 2 (Helios)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF2chr2_-_2140163320.261.1e-04Click!


Activity profile for motif IKZF2.p2.

activity profile for motif IKZF2.p2


Sorted Z-values histogram for motif IKZF2.p2

Sorted Z-values for motif IKZF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_80523376 34.000 STMN2
stathmin-like 2
chr11_-_62472901 25.514


chr1_+_155853546 24.916 SYT11
synaptotagmin XI
chr3_-_195310985 24.246 NM_001647
 APOD
apolipoprotein D
chr18_-_74728963 22.298 MBP
myelin basic protein
chr18_-_74729049 22.076 NM_001025081
NM_001025090
NM_001025092
NM_002385
 MBP



myelin basic protein



chr4_-_176734181 21.662 NM_201591
 GPM6A
glycoprotein M6A
chr7_+_86273219 21.458 NM_000840
 GRM3
glutamate receptor, metabotropic 3
chr5_-_42811959 21.057 NM_001085486
NM_001093726
NM_005410
 SEPP1


selenoprotein P, plasma, 1


chrX_+_103031433 20.696 NM_001128834
 PLP1
proteolipid protein 1
chrX_+_103031797 20.470 PLP1
proteolipid protein 1
chr1_-_93399531 20.233


chr3_-_195310770 20.078 APOD
apolipoprotein D
chr3_-_58563070 19.754 FAM107A
family with sequence similarity 107, member A
chrX_+_103031753 19.683 NM_000533
NM_199478
 PLP1

proteolipid protein 1

chr4_-_153303663 19.424 NM_001013415
 FBXW7
F-box and WD repeat domain containing 7
chrX_+_73164162 18.497 JPX
JPX transcript, XIST activator (non-protein coding)
chr7_-_64023444 17.920


chr5_-_146460991 17.574 NM_181677
NM_181678
 PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr7_-_137028275 17.511 PTN
pleiotrophin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
2.35 1.96e-02 GO:0007156 homophilic cell adhesion
2.29 1.28e-02 GO:0050900 leukocyte migration
1.89 3.29e-04 GO:0016477 cell migration
1.88 5.34e-09 GO:0007155 cell adhesion
1.88 5.34e-09 GO:0022610 biological adhesion
1.84 4.56e-02 GO:0016337 cell-cell adhesion
1.80 1.80e-03 GO:0050776 regulation of immune response
1.79 1.55e-03 GO:0048870 cell motility
1.79 1.55e-03 GO:0051674 localization of cell
1.72 8.88e-07 GO:0040011 locomotion
1.71 2.00e-02 GO:0002684 positive regulation of immune system process
1.70 2.76e-03 GO:0006928 cellular component movement
1.69 1.20e-02 GO:0007596 blood coagulation
1.69 1.20e-02 GO:0050817 coagulation
1.68 1.54e-02 GO:0007599 hemostasis
1.67 1.44e-02 GO:0006935 chemotaxis
1.67 1.44e-02 GO:0042330 taxis
1.65 1.05e-05 GO:0009611 response to wounding
1.65 5.79e-03 GO:0042060 wound healing
1.65 3.95e-02 GO:0019226 transmission of nerve impulse

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.71 3.79e-02 GO:0005578 proteinaceous extracellular matrix
1.56 4.08e-04 GO:0005615 extracellular space
1.52 7.15e-05 GO:0044421 extracellular region part
1.51 5.63e-06 GO:0031226 intrinsic to plasma membrane
1.51 6.94e-06 GO:0005887 integral to plasma membrane
1.40 4.77e-07 GO:0044459 plasma membrane part
1.32 4.28e-04 GO:0005576 extracellular region
1.21 5.73e-04 GO:0005886 plasma membrane
1.20 9.64e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
7.70 1.45e-02 GO:0005132 interferon-alpha/beta receptor binding
5.14 3.64e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.12 8.17e-03 GO:0005515 protein binding
1.06 2.11e-02 GO:0005488 binding