Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 1.525


Transcription factors associated with LEF1_TCF7_TCF7L1,2.p2:

Gene SymbolEntrez IDGene Name
LEF1 51176 lymphoid enhancer-binding factor 1
TCF7 6932 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 83439 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF7L1chr2_+_853603730.551.4e-18Click!
TCF7L2chr10_+_1147107850.211.6e-03Click!
LEF1chr4_-_109087876-0.186.3e-03Click!
TCF7chr5_+_133451297-0.188.3e-03Click!


Activity profile for motif LEF1_TCF7_TCF7L1,2.p2.

activity profile for motif LEF1_TCF7_TCF7L1,2.p2


Sorted Z-values histogram for motif LEF1_TCF7_TCF7L1,2.p2

Sorted Z-values for motif LEF1_TCF7_TCF7L1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LEF1_TCF7_TCF7L1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_91573264 22.838 NM_133503
DCN
decorin
chr9_+_74526527 22.391 C9orf85
chromosome 9 open reading frame 85
chr11_-_117747331 20.993 FXYD6
FXYD domain containing ion transport regulator 6
chr12_-_16759939 19.566 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr13_+_111137249 19.140 COL4A2
collagen, type IV, alpha 2
chr17_-_42992852 18.401 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr12_-_16759531 18.146 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_+_21572736 18.123 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr10_+_7745341 17.826 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr7_+_94023872 17.140 NM_000089
COL1A2
collagen, type I, alpha 2
chr4_-_5894695 16.129 NM_001014809
CRMP1
collapsin response mediator protein 1
chr13_+_111134933 14.690 COL4A2
collagen, type IV, alpha 2
chr7_+_94024201 14.491 COL1A2
collagen, type I, alpha 2
chr1_-_182361311 14.089 NM_001033044
NM_002065
GLUL

glutamate-ammonia ligase

chr8_+_80523048 13.654 NM_001199214
NM_007029
STMN2

stathmin-like 2

chr10_+_7745354 13.588 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745325 13.274 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr6_+_7108864 13.053 RREB1
ras responsive element binding protein 1
chr12_-_16759430 12.971 LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_22089517 12.966 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr11_-_76155704 12.671


chr20_+_36149606 12.480 NM_005386
NM_181689
NNAT

neuronatin

chr8_+_80523351 12.366 STMN2
stathmin-like 2
chrX_-_13835012 12.359 GPM6B
glycoprotein M6B
chr5_-_58334936 12.239 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr10_+_7745284 12.222 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_186877413 12.095 SORBS2
sorbin and SH3 domain containing 2
chr8_+_80523304 11.998 STMN2
stathmin-like 2
chr10_+_7745229 11.607 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr14_-_21271002 11.186 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr15_-_42783293 11.178 ZFP106
zinc finger protein 106 homolog (mouse)
chr18_-_25757351 11.164 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chrX_+_135229536 11.142 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr16_-_46865039 11.024 NM_001001436
C16orf87
chromosome 16 open reading frame 87
chr15_+_43885251 10.893 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr2_-_86564632 10.890 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr10_-_88717319 10.713 NM_024756
MMRN2
multimerin 2
chr12_-_16759733 10.237 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr19_-_17375522 10.219 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr8_+_80523339 10.161 STMN2
stathmin-like 2
chr13_-_25496913 10.159 CENPJ
centromere protein J
chr7_-_107643330 10.108 NM_002291
LAMB1
laminin, beta 1
chr8_-_119964059 10.017 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr12_+_57943843 9.877 NM_004984
KIF5A
kinesin family member 5A
chr5_+_36606667 9.717 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_22089850 9.716 NM_001099335
NM_014759
PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr13_+_111138079 9.511 COL4A2
collagen, type IV, alpha 2
chr2_+_11680079 9.414 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr19_-_55690717 9.398 SYT5
synaptotagmin V
chr14_+_74486049 9.304 NM_025057
C14orf45
chromosome 14 open reading frame 45
chr6_+_121756744 9.292 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr18_-_25756946 9.263 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_+_69240137 9.170 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr1_+_24882565 9.125 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr12_+_112204690 9.014 NM_000690
NM_001204889
ALDH2

aldehyde dehydrogenase 2 family (mitochondrial)

chr14_-_74485813 8.913 NM_001249
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr7_-_137028370 8.906 PTN
pleiotrophin
chr7_-_137028533 8.869 NM_002825
PTN
pleiotrophin
chr9_+_17578952 8.816 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr17_-_39093671 8.637 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr14_-_21270537 8.635 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr8_-_6914251 8.579 NM_021010
DEFA5
defensin, alpha 5, Paneth cell-specific
chr17_+_44101549 8.520 MAPT
microtubule-associated protein tau
chr7_+_30951414 8.400 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr1_-_177133818 8.301 ASTN1
astrotactin 1
chr1_-_177133950 8.284 NM_004319
NM_207108
ASTN1

astrotactin 1

chr17_+_57297827 8.279 NM_001165993
NM_001165994
NM_182569
GDPD1


glycerophosphodiester phosphodiesterase domain containing 1


chr15_+_80696569 8.004 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr1_-_43424324 7.988 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr8_-_33424642 7.946 NM_024787
RNF122
ring finger protein 122
chr3_-_123339178 7.941 MYLK
myosin light chain kinase
chr3_-_123339423 7.902 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr1_+_82266081 7.885 NM_012302
LPHN2
latrophilin 2
chr19_-_40791145 7.861 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr9_+_74526369 7.859 NM_182505
C9orf85
chromosome 9 open reading frame 85
chr4_-_10686314 7.800 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr12_+_112204711 7.783 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr9_-_21239975 7.749 NM_002172
IFNA14
interferon, alpha 14
chr15_+_64443909 7.705 NM_024798
SNX22
sorting nexin 22
chr5_+_36606456 7.701 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr6_+_83073954 7.619 NM_001166392
TPBG
trophoblast glycoprotein
chr2_-_170218972 7.505 LRP2
low density lipoprotein receptor-related protein 2
chr20_-_43977023 7.478 NM_002999
SDC4
syndecan 4
chr7_-_137028433 7.447 PTN
pleiotrophin
chr17_+_72428228 7.446 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr4_-_85419386 7.425 NM_006168
NKX6-1
NK6 homeobox 1
chr8_+_80523376 7.422 STMN2
stathmin-like 2
chr5_+_140734767 7.407 NM_018917
NM_032053
PCDHGA4

protocadherin gamma subfamily A, 4

chr3_+_189349215 7.386 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr1_-_16345284 7.316 NM_014424
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr8_-_121824015 7.294


chr20_+_17207596 7.268 NM_001201529
NM_002594
PCSK2

proprotein convertase subtilisin/kexin type 2

chr14_-_21493122 7.194 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr5_+_140771482 7.165 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chrX_+_46937744 7.157 NM_004683
NM_152869
RGN

regucalcin (senescence marker protein-30)

chr12_+_53491417 7.095 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr16_-_49315682 7.054 NM_004352
CBLN1
cerebellin 1 precursor
chr19_+_18062110 7.031 NM_002248
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr14_+_93389444 6.995 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr19_-_48867149 6.977 NM_018273
TMEM143
transmembrane protein 143
chr14_-_60097223 6.961 RTN1
reticulon 1
chr3_+_137483133 6.913 NM_004189
SOX14
SRY (sex determining region Y)-box 14
chr19_-_6720585 6.811 NM_000064
C3
complement component 3
chrX_+_152760346 6.808 NM_001711
BGN
biglycan
chr10_-_52645384 6.767 A1CF
APOBEC1 complementation factor
chr7_-_120498128 6.765 NM_012338
TSPAN12
tetraspanin 12
chr3_+_52813936 6.761 NM_001166435
NM_001166436
ITIH1

inter-alpha-trypsin inhibitor heavy chain 1

chr20_-_32031425 6.740 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr17_+_7960201 6.740


chr6_-_52668599 6.732 NM_145740
GSTA1
glutathione S-transferase alpha 1
chrX_+_152760452 6.698 BGN
biglycan
chr5_-_157002705 6.635


chr1_-_43424536 6.608 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr11_+_46740769 6.557 F2
coagulation factor II (thrombin)
chrX_-_106362018 6.555 RBM41
RNA binding motif protein 41
chr1_+_17846818 6.555 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr5_+_140753480 6.522 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr12_-_16760935 6.512 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr3_+_29322802 6.505 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr12_-_122296619 6.501 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr2_+_219724545 6.494 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr1_-_178062734 6.451 LOC100302401
uncharacterized LOC100302401
chr2_+_169926084 6.441 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr3_+_123813527 6.416 NM_001024660
NM_003947
KALRN

kalirin, RhoGEF kinase

chr1_+_9299902 6.348 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr13_+_102104941 6.327 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr14_-_60097314 6.317 RTN1
reticulon 1
chr11_+_46740736 6.277 NM_000506
F2
coagulation factor II (thrombin)
chr18_-_31802433 6.277 NM_001198547
NOL4
nucleolar protein 4
chr5_+_140797243 6.226 NM_018927
PCDHGB7
protocadherin gamma subfamily B, 7
chr6_-_28220001 6.219 NM_019110
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chrX_-_32173585 6.219 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr2_+_16080639 6.216 NM_005378
MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr17_+_56315786 6.204 NM_001160102
NM_006151
LPO

lactoperoxidase

chr10_-_5045967 6.195 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr13_+_39612440 6.190 NM_001012754
NM_001017370
NHLRC3

NHL repeat containing 3

chr11_-_72385411 6.190 NM_002599
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr19_-_40791265 6.105 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr7_-_137028275 6.064 PTN
pleiotrophin
chr1_+_93913566 6.034 NM_001024948
NM_001164473
NM_017737
FNBP1L


formin binding protein 1-like


chr3_-_167813175 6.005 NM_014498
GOLIM4
golgi integral membrane protein 4
chr1_+_13911966 6.000 NM_001006624
NM_001006625
PDPN

podoplanin

chr10_-_13749622 5.945 FRMD4A
FERM domain containing 4A
chr19_-_40791224 5.935 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr6_-_24645955 5.892 NM_001168375
NM_001168376
NM_001168374
NM_001168377
NM_014809
KIAA0319




KIAA0319




chr10_+_71561643 5.890 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr6_+_41040713 5.888 NFYA
nuclear transcription factor Y, alpha
chr11_+_61129831 5.841 TMEM138
transmembrane protein 138
chr12_+_70759974 5.835 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_-_128568666 5.775 WDR33
WD repeat domain 33
chr17_+_36861398 5.754 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_+_149632772 5.733 NM_004522
KIF5C
kinesin family member 5C
chr15_+_44580870 5.688 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chr11_-_75921785 5.656 WNT11
wingless-type MMTV integration site family, member 11
chr13_-_27334777 5.638 NM_005288
GPR12
G protein-coupled receptor 12
chr1_+_244998967 5.631 FAM36A
family with sequence similarity 36, member A
chr3_-_187388105 5.628 NM_001048
SST
somatostatin
chr10_+_71561687 5.602 COL13A1
collagen, type XIII, alpha 1
chr20_+_17206751 5.583 NM_001201528
PCSK2
proprotein convertase subtilisin/kexin type 2
chr16_+_72097124 5.568 NM_020995
HPR
haptoglobin-related protein
chr1_-_173886401 5.543 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_+_209878135 5.513 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr6_+_27925018 5.502 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr8_+_121823538 5.499


chr10_+_14920781 5.482 NM_001193424
NM_001193426
NM_001193425
NM_001193427
NM_024670
SUV39H2




suppressor of variegation 3-9 homolog 2 (Drosophila)




chr1_-_95392501 5.475 NM_001839
CNN3
calponin 3, acidic
chr1_+_244998592 5.329 NM_198076
FAM36A
family with sequence similarity 36, member A
chr19_-_6502224 5.325 NM_006087
TUBB4A
tubulin, beta 4A class IVa
chr6_-_90024936 5.316 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr19_-_40791248 5.310 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr8_+_105352050 5.301 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr1_+_150255228 5.283 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr2_+_105471745 5.271 NM_006236
POU3F3
POU class 3 homeobox 3
chr12_+_32654976 5.257 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_+_159557745 5.212 SCHIP1
schwannomin interacting protein 1
chr17_-_2996289 5.195 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr1_-_225840660 5.149 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr8_-_121823696 5.127 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr1_-_173886464 5.125 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_+_196912910 5.111 NM_005666
CFHR2
complement factor H-related 2
chr20_+_34556528 5.097 NM_001207076
NM_080834
C20orf152

chromosome 20 open reading frame 152

chr9_-_21217303 5.084 NM_002173
IFNA16
interferon, alpha 16
chr16_-_48419148 5.081 NM_003031
SIAH1
seven in absentia homolog 1 (Drosophila)
chr12_+_62860816 5.054 MON2
MON2 homolog (S. cerevisiae)
chr17_+_77751929 5.038 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr8_-_145701717 5.031 NM_003923
FOXH1
forkhead box H1
chr1_+_19971865 5.028 NM_001204085
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr2_+_172378756 5.012 CYBRD1
cytochrome b reductase 1
chr19_-_3028901 5.006 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr11_+_113848221 4.972 NM_001161772
HTR3A
5-hydroxytryptamine (serotonin) receptor 3A
chr12_+_32260084 4.941 NM_001003398
NM_001714
BICD1

bicaudal D homolog 1 (Drosophila)

chr7_-_64451413 4.940 NM_015852
ZNF117
zinc finger protein 117
chrX_+_102632108 4.928 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr19_+_37407230 4.913 NM_001204835
NM_001204836
NM_001204837
NM_001204838
NM_001204839
NM_198539
ZNF568





zinc finger protein 568





chr4_-_120243257 4.886 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr22_-_36013303 4.881 NM_005368
NM_203378
MB

myoglobin

chr5_+_140797270 4.857 PCDHGB7
protocadherin gamma subfamily B, 7
chr17_+_30813928 4.827 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr3_+_159557649 4.806 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr15_-_89764809 4.802 NM_000326
RLBP1
retinaldehyde binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 6.33e-14 GO:0032501 multicellular organismal process
1.54 2.30e-13 GO:0048856 anatomical structure development
1.86 3.69e-13 GO:0007399 nervous system development
1.46 1.17e-12 GO:0032502 developmental process
1.49 3.87e-12 GO:0007275 multicellular organismal development
1.53 2.48e-11 GO:0048731 system development
1.95 6.89e-09 GO:0022008 neurogenesis
1.97 9.21e-09 GO:0048699 generation of neurons
1.88 5.73e-07 GO:0040011 locomotion
1.98 8.33e-07 GO:0030182 neuron differentiation
1.20 1.53e-06 GO:0065007 biological regulation
1.50 1.81e-06 GO:0048869 cellular developmental process
1.49 7.47e-06 GO:0030154 cell differentiation
1.59 1.08e-05 GO:0009653 anatomical structure morphogenesis
1.71 3.84e-05 GO:0009605 response to external stimulus
2.05 4.08e-05 GO:0048858 cell projection morphogenesis
2.30 5.33e-05 GO:0007411 axon guidance
1.94 5.38e-05 GO:0000902 cell morphogenesis
1.82 5.65e-05 GO:0007155 cell adhesion
1.82 5.65e-05 GO:0022610 biological adhesion
2.03 5.76e-05 GO:0032990 cell part morphogenesis
2.00 1.04e-04 GO:0006935 chemotaxis
2.00 1.04e-04 GO:0042330 taxis
2.09 1.78e-04 GO:0007409 axonogenesis
1.87 1.88e-04 GO:0030030 cell projection organization
1.43 1.93e-04 GO:0065008 regulation of biological quality
2.06 2.05e-04 GO:0048812 neuron projection morphogenesis
1.87 2.23e-04 GO:0032989 cellular component morphogenesis
3.02 2.46e-04 GO:0007156 homophilic cell adhesion
1.30 2.48e-04 GO:0023052 signaling
2.06 2.62e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.96 5.75e-04 GO:0031175 neuron projection development
2.01 1.50e-03 GO:0016477 cell migration
1.86 1.56e-03 GO:0006928 cellular component movement
1.10 1.74e-03 GO:0009987 cellular process
1.91 1.86e-03 GO:0000904 cell morphogenesis involved in differentiation
1.29 2.01e-03 GO:0007165 signal transduction
1.83 2.49e-03 GO:0048666 neuron development
1.37 3.28e-03 GO:0042221 response to chemical stimulus
1.69 4.49e-03 GO:2000026 regulation of multicellular organismal development
3.16 4.54e-03 GO:0007586 digestion
1.90 6.20e-03 GO:0048870 cell motility
1.90 6.20e-03 GO:0051674 localization of cell
1.41 6.89e-03 GO:0007166 cell surface receptor linked signaling pathway
1.60 7.72e-03 GO:0050793 regulation of developmental process
1.18 1.03e-02 GO:0050896 response to stimulus
1.24 1.24e-02 GO:0051716 cellular response to stimulus
1.15 1.35e-02 GO:0050789 regulation of biological process
1.16 1.63e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.91 5.59e-11 GO:0044421 extracellular region part
1.92 3.92e-08 GO:0005615 extracellular space
1.46 3.92e-06 GO:0005576 extracellular region
1.42 1.55e-05 GO:0044459 plasma membrane part
1.24 8.64e-04 GO:0005886 plasma membrane
1.23 1.78e-03 GO:0071944 cell periphery
1.48 2.22e-03 GO:0005887 integral to plasma membrane
1.46 3.37e-03 GO:0031226 intrinsic to plasma membrane
2.63 1.39e-02 GO:0044420 extracellular matrix part
1.80 2.55e-02 GO:0031012 extracellular matrix
1.50 3.48e-02 GO:0005626 insoluble fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.50 1.27e-02 GO:0005102 receptor binding
1.62 1.64e-02 GO:0005509 calcium ion binding
3.01 2.04e-02 GO:0005201 extracellular matrix structural constituent
6.19 3.33e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity