Motif ID: LHX3,4.p2

Z-value: 1.022


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LHX3chr9_-_1390948860.171.4e-02Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_13835012 27.834 GPM6B
glycoprotein M6B
chr14_+_92788924 17.284 NM_153648
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr1_+_155853546 16.849 SYT11
synaptotagmin XI
chr1_+_198608216 15.828 PTPRC
protein tyrosine phosphatase, receptor type, C
chr19_+_9296269 14.001 NM_175883
 OR7D2
olfactory receptor, family 7, subfamily D, member 2
chrX_-_13835187 13.802 GPM6B
glycoprotein M6B
chr12_+_75784878 13.204 NM_152436
 GLIPR1L2
GLI pathogenesis-related 1 like 2
chr3_-_195310985 13.046 NM_001647
 APOD
apolipoprotein D
chr2_+_103089761 12.095 NM_001011552
 SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chrX_-_13835313 11.671 NM_001001995
NM_001001996
NM_005278
 GPM6B


glycoprotein M6B


chr3_-_195310770 10.760 APOD
apolipoprotein D
chr12_+_8332789 10.509 FAM66C
family with sequence similarity 66, member C
chr12_-_10021932 9.974 CLEC2B
C-type lectin domain family 2, member B
chr3_+_101546833 9.744 NM_001005474
 NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr4_-_120243257 8.973 NM_000134
 FABP2
fatty acid binding protein 2, intestinal
chr2_-_175462428 8.848 WIPF1
WAS/WASL interacting protein family, member 1
chr12_-_10282680 8.745 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
 CLEC7A





C-type lectin domain family 7, member A





chr10_+_17270257 8.434 NM_003380
 VIM
vimentin
chr3_-_69171536 8.392 NM_198271
 LMOD3
leiomodin 3 (fetal)
chr5_+_67586466 8.075 NM_181504
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
6.67 2.83e-02 GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity
2.27 1.34e-02 GO:0050776 regulation of immune response
2.25 2.30e-05 GO:0006955 immune response
2.22 3.66e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
2.15 1.86e-04 GO:0007267 cell-cell signaling
2.07 3.05e-03 GO:0002682 regulation of immune system process
1.96 2.21e-04 GO:0007154 cell communication
1.96 4.12e-03 GO:0006952 defense response
1.93 1.81e-05 GO:0002376 immune system process
1.61 4.18e-03 GO:0003008 system process
1.60 4.16e-03 GO:0007166 cell surface receptor linked signaling pathway
1.58 3.81e-03 GO:0048583 regulation of response to stimulus
1.49 3.11e-06 GO:0023052 signaling
1.44 5.30e-04 GO:0007165 signal transduction
1.31 7.86e-04 GO:0032501 multicellular organismal process
1.30 7.50e-05 GO:0050896 response to stimulus
1.30 4.50e-02 GO:0051716 cellular response to stimulus
1.21 2.64e-03 GO:0065007 biological regulation
1.21 1.50e-02 GO:0050794 regulation of cellular process
1.20 1.88e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.81 5.87e-05 GO:0005887 integral to plasma membrane
1.78 1.22e-04 GO:0031226 intrinsic to plasma membrane
1.56 1.08e-04 GO:0044459 plasma membrane part
1.53 7.70e-04 GO:0005576 extracellular region
1.41 3.39e-06 GO:0005886 plasma membrane
1.41 3.77e-06 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
10.12 3.14e-02 GO:0005248 voltage-gated sodium channel activity
7.09 1.51e-02 GO:0004435 phosphatidylinositol phospholipase C activity