Motif ID: LMO2.p2

Z-value: 1.504


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LMO2chr11_-_33913835,
chr11_-_33891485,
chr11_-_33891258,
chr11_-_33890931
0.228.9e-04Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_13956445 29.669


chr1_+_1981902 23.012 NM_002744
PRKCZ
protein kinase C, zeta
chr16_+_23847271 22.292 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chrX_-_13956644 22.029 NM_001001994
GPM6B
glycoprotein M6B
chr16_+_58497628 21.817 NDRG4
NDRG family member 4
chr16_+_58497993 21.105 NM_001130487
NDRG4
NDRG family member 4
chrX_-_13956530 21.084 GPM6B
glycoprotein M6B
chr5_+_156693051 20.603 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr7_-_766875 20.261 NM_001164760
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_+_58497548 20.074 NM_020465
NDRG4
NDRG family member 4
chr19_+_38755238 19.512 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755097 18.908 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr20_+_44034632 18.294 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr18_-_74691951 18.263 MBP
myelin basic protein
chr16_+_23847321 17.988 PRKCB
protein kinase C, beta
chr20_+_44035203 17.299 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr2_+_79740059 16.954 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr19_+_38755422 16.764 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr7_-_124405029 16.465 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_65720091 16.243 LOC645195
DNAJC6
uncharacterized LOC645195
DnaJ (Hsp40) homolog, subfamily C, member 6
chr16_-_57318452 16.203 PLLP
plasmolipin
chr16_+_23847359 15.749 PRKCB
protein kinase C, beta
chr2_+_79740171 15.496 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr1_+_233749749 15.190 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr19_+_54926604 14.952 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chrX_-_118827116 14.399 SEPT6
septin 6
chr4_-_176923572 14.042 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr14_+_100150596 13.403 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr19_-_46974663 13.396 PNMAL1
PNMA-like 1
chr4_-_36245893 13.342 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_-_23822025 13.073 NM_016609
SLC22A17
solute carrier family 22, member 17
chr9_-_93405066 13.050 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr6_-_3227776 13.031 NM_178012
TUBB2B
tubulin, beta 2B class IIb
chr19_+_47104389 12.558 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr9_-_101470836 12.347 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr17_+_7554415 12.292 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chrX_-_118827155 12.200 SEPT6
septin 6
chr19_-_46974789 12.137 NM_001103149
NM_018215
PNMAL1

PNMA-like 1

chr19_+_47104559 12.025 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr7_-_37488894 11.942 NM_001206480
ELMO1
engulfment and cell motility 1
chr7_-_767286 11.756 NM_001164758
NM_001164759
PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

chr4_-_176923480 11.694 GPM6A
glycoprotein M6A
chr4_-_176923533 11.608 GPM6A
glycoprotein M6A
chr11_-_694842 11.597 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr19_-_6502224 11.375 NM_006087
TUBB4A
tubulin, beta 4A class IVa
chr7_-_994008 11.328 ADAP1
ArfGAP with dual PH domains 1
chr4_-_17513676 10.844 NM_000320
QDPR
quinoid dihydropteridine reductase
chr3_+_50712671 10.750 NM_004947
DOCK3
dedicator of cytokinesis 3
chr19_+_47104490 10.674 NM_005184
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr5_+_169064238 10.647 NM_004946
DOCK2
dedicator of cytokinesis 2
chr14_-_60097531 10.454 NM_206852
RTN1
reticulon 1
chr1_+_233749917 10.399 KCNK1
potassium channel, subfamily K, member 1
chr20_+_10199455 9.943 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr10_+_11060105 9.917 CELF2
CUGBP, Elav-like family member 2
chr9_+_130965666 9.895 DNM1
dynamin 1
chr5_+_169064274 9.683 DOCK2
dedicator of cytokinesis 2
chr9_-_139922705 9.630 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr2_+_149632772 9.459 NM_004522
KIF5C
kinesin family member 5C
chr8_+_86376130 9.411 NM_000067
CA2
carbonic anhydrase II
chr1_-_85930610 9.379 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr11_+_73358593 9.155 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr14_-_60097314 9.094 RTN1
reticulon 1
chr16_+_58498182 9.045 NDRG4
NDRG family member 4
chr14_-_60097223 8.938 RTN1
reticulon 1
chr1_+_228675042 8.932 NM_001010858
RNF187
ring finger protein 187
chr1_-_26232890 8.700 NM_001145454
NM_005563
STMN1

stathmin 1

chr4_+_41258909 8.674 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_41258895 8.635 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr2_+_17721806 8.510 NM_003385
VSNL1
visinin-like 1
chr2_+_95691428 8.505 NM_002371
NM_022438
NM_022439
NM_022440
MAL



mal, T-cell differentiation protein



chr4_+_41258941 8.488 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr19_-_42498320 8.475 NM_152296
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr12_+_7023490 8.452 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr7_+_75039632 8.373 NSUN5P1
NOP2/Sun domain family, member 5 pseudogene 1
chr2_-_175869910 8.290 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr3_+_167453431 8.174 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr15_+_32933869 8.160 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr18_-_74844762 8.145 NM_001025100
NM_001025101
MBP

myelin basic protein

chr10_-_15413054 8.129 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr16_+_58498216 8.076 NDRG4
NDRG family member 4
chr12_+_122459791 8.072 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr19_-_7939325 8.061 NM_001190467
FLJ22184
putative uncharacterized protein FLJ22184
chr3_-_47620186 8.058 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr10_+_105037441 7.993 INA
internexin neuronal intermediate filament protein, alpha
chr9_+_130965668 7.919 DNM1
dynamin 1
chr6_-_84419108 7.915 NM_001242793
NM_001242794
NM_014841
SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr14_+_104029278 7.907 NM_032374
APOPT1
apoptogenic 1
chr9_+_17578952 7.902 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr12_-_46662779 7.861 SLC38A1
solute carrier family 38, member 1
chr16_+_56623266 7.849 NM_005954
MT3
metallothionein 3
chr12_-_46662709 7.847 SLC38A1
solute carrier family 38, member 1
chr17_-_4890664 7.833 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr9_+_130965608 7.825 NM_001005336
NM_004408
DNM1

dynamin 1

chr7_-_37488408 7.812 ELMO1
engulfment and cell motility 1
chr7_+_149571029 7.719 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr1_+_2005424 7.585 NM_001242874
PRKCZ
protein kinase C, zeta
chr3_+_133494275 7.571 TF
transferrin
chr7_-_37488554 7.569 NM_014800
ELMO1
engulfment and cell motility 1
chr20_+_37434294 7.533 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr7_-_51384458 7.445 NM_015198
COBL
cordon-bleu homolog (mouse)
chr14_-_103988829 7.439 CKB
creatine kinase, brain
chr16_+_2039945 7.433 NM_004209
SYNGR3
synaptogyrin 3
chr1_-_85930733 7.418 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_-_38856830 7.403 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr2_+_17721983 7.361 VSNL1
visinin-like 1
chr3_+_184056304 7.287 FAM131A
family with sequence similarity 131, member A
chr6_+_107811272 7.266 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr19_-_42498221 7.220 ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr6_-_46459010 7.215 NM_001251974
RCAN2
regulator of calcineurin 2
chr7_-_30029284 7.165 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr12_-_46663207 7.151 NM_001077484
NM_030674
SLC38A1

solute carrier family 38, member 1

chr13_-_36705432 7.085 DCLK1
doublecortin-like kinase 1
chr20_-_3149070 7.010 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr14_-_21493910 6.923 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr7_-_44365019 6.900 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chrX_-_118827060 6.854 SEPT6
septin 6
chr16_-_2390737 6.805 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr10_-_118764559 6.805 KIAA1598
KIAA1598
chr14_-_21493858 6.804 NDRG2
NDRG family member 2
chr9_-_91793375 6.798 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr14_-_23821423 6.798 NM_020372
SLC22A17
solute carrier family 22, member 17
chr15_+_89182038 6.767 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr19_+_35782988 6.717 NM_001199216
NM_002361
NM_080600
MAG


myelin associated glycoprotein


chr2_+_149632836 6.677 KIF5C
kinesin family member 5C
chr22_+_29876180 6.594 NM_021076
NEFH
neurofilament, heavy polypeptide
chr3_+_35681008 6.531 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr4_-_42658883 6.489 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr3_-_18466759 6.488 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr16_-_57318574 6.448 NM_015993
PLLP
plasmolipin
chr16_+_14164879 6.429 NM_014048
MKL2
MKL/myocardin-like 2
chr17_+_7554239 6.410 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr22_-_51021200 6.388 CHKB
choline kinase beta
chr19_+_36359346 6.351 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr10_-_98945662 6.321 NM_003061
SLIT1
slit homolog 1 (Drosophila)
chr9_-_136024522 6.254 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr2_+_149633173 6.226


chr17_+_7554711 6.201 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr9_-_139923214 6.178 NM_212533
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr9_-_139940595 6.176 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr11_-_33890931 6.153 LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_+_54926721 6.127 TTYH1
tweety homolog 1 (Drosophila)
chr19_-_19006868 6.120 NM_021267
NM_198207
NM_001492
CERS1

GDF1
ceramide synthase 1

growth differentiation factor 1
chr1_+_169075869 6.112 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr11_-_695010 6.096 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr7_-_994259 6.083 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr3_-_10547340 6.055 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr17_+_19912608 6.030 NM_001243439
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr9_-_139940556 6.021 NPDC1
neural proliferation, differentiation and control, 1
chr9_-_92112887 6.020 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chrX_+_53111482 5.909 NM_022117
TSPYL2
TSPY-like 2
chr22_-_50893728 5.898 SBF1
SET binding factor 1
chr6_-_84419018 5.837 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr12_-_112819755 5.808 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chrX_-_92928566 5.808 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr2_-_224702200 5.780 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr14_-_21493122 5.743 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr19_+_5904842 5.734 NM_001017921
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr11_+_46354454 5.730 NM_201532
DGKZ
diacylglycerol kinase, zeta
chr7_-_73123431 5.727 STX1A
syntaxin 1A (brain)
chr8_+_26371461 5.688 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr2_-_73496595 5.661 NM_001080410
FBXO41
F-box protein 41
chr17_+_16593571 5.653 NM_014695
CCDC144B
CCDC144A
coiled-coil domain containing 144B (pseudogene)
coiled-coil domain containing 144A
chr22_+_38453478 5.618 PICK1
protein interacting with PRKCA 1
chr5_-_179285791 5.613 NM_001017987
NM_016175
C5orf45

chromosome 5 open reading frame 45

chr14_+_96505566 5.606 NM_001252507
C14orf132
chromosome 14 open reading frame 132
chr3_-_49907304 5.588 NM_024046
CAMKV
CaM kinase-like vesicle-associated
chr19_-_58609606 5.502 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr5_+_173472737 5.480 HMP19
HMP19 protein
chr12_+_7342956 5.478 NM_000319
PEX5
peroxisomal biogenesis factor 5
chr7_-_72425211 5.476 NSUN5P1
NSUN5P2
NOP2/Sun domain family, member 5 pseudogene 1
NOP2/Sun domain family, member 5 pseudogene 2
chr9_-_139940464 5.470 NPDC1
neural proliferation, differentiation and control, 1
chr3_-_120068077 5.351 NM_001099678
LRRC58
leucine rich repeat containing 58
chr13_+_113656027 5.310 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr7_-_72722786 5.296 NM_001168347
NM_001168348
NM_018044
NM_148956
NSUN5



NOP2/Sun domain family, member 5



chr14_+_105781180 5.290 PACS2
phosphofurin acidic cluster sorting protein 2
chr1_+_6094342 5.285 NM_001199860
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_-_143059144 5.279 NM_014690
FAM131B
family with sequence similarity 131, member B
chr16_+_7382750 5.262 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr7_-_124405680 5.239 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr17_-_4890920 5.213 NM_001171166
NM_015099
CAMTA2

calmodulin binding transcription activator 2

chr9_+_87284625 5.203 NM_001007097
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chrX_-_118827322 5.188 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr16_-_2390711 5.180 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_-_233431458 5.164 NM_014801
PCNXL2
pecanex-like 2 (Drosophila)
chr19_-_36523540 5.106 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr1_-_226595533 5.063 PARP1
poly (ADP-ribose) polymerase 1
chr2_+_173600634 5.045 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr9_-_10612722 5.044 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr22_+_32870829 5.024 FBXO7
F-box protein 7
chr10_-_46342906 5.012 NM_133446
AGAP4
ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
chr1_+_78354199 5.011 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr8_-_103137134 5.009 NM_001040630
NCALD
neurocalcin delta
chr8_-_103136486 4.982 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
NCALD





neurocalcin delta





chr1_-_40782981 4.969 COL9A2
collagen, type IX, alpha 2
chr17_+_43299277 4.958 NM_005892
FMNL1
formin-like 1
chr5_-_88199868 4.944 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr17_-_79139871 4.938 NM_001080395
AATK
apoptosis-associated tyrosine kinase
chr11_-_72380107 4.935 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr10_+_11060069 4.910 CELF2
CUGBP, Elav-like family member 2
chr1_-_41131323 4.909 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 2.63e-10 GO:0023052 signaling
1.17 1.60e-08 GO:0065007 biological regulation
2.03 3.81e-07 GO:0051056 regulation of small GTPase mediated signal transduction
1.48 5.78e-07 GO:0007399 nervous system development
1.50 7.12e-07 GO:0035556 intracellular signal transduction
1.17 8.19e-07 GO:0050794 regulation of cellular process
1.87 8.32e-07 GO:0019226 transmission of nerve impulse
1.87 8.32e-07 GO:0035637 multicellular organismal signaling
1.29 1.51e-06 GO:0007165 signal transduction
1.91 1.54e-06 GO:0007268 synaptic transmission
1.16 2.02e-06 GO:0050789 regulation of biological process
1.10 4.01e-06 GO:0009987 cellular process
1.41 1.98e-05 GO:0023051 regulation of signaling
1.25 4.82e-05 GO:0051179 localization
1.21 3.13e-04 GO:0051716 cellular response to stimulus
1.24 1.04e-03 GO:0048856 anatomical structure development
1.52 1.09e-03 GO:0016310 phosphorylation
1.25 1.30e-03 GO:0006810 transport
1.32 1.85e-03 GO:0048583 regulation of response to stimulus
4.31 1.90e-03 GO:0032312 regulation of ARF GTPase activity
1.24 1.94e-03 GO:0051234 establishment of localization
1.25 2.64e-03 GO:0048731 system development
3.48 2.79e-03 GO:0032012 regulation of ARF protein signal transduction
1.21 3.55e-03 GO:0032502 developmental process
1.93 4.30e-03 GO:0046578 regulation of Ras protein signal transduction
1.52 4.77e-03 GO:0006468 protein phosphorylation
1.69 5.15e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.21 5.26e-03 GO:0007275 multicellular organismal development
1.68 5.51e-03 GO:0048812 neuron projection morphogenesis
2.37 6.69e-03 GO:0050804 regulation of synaptic transmission
1.50 7.28e-03 GO:0007267 cell-cell signaling
1.28 7.74e-03 GO:0065008 regulation of biological quality
1.35 1.26e-02 GO:0009966 regulation of signal transduction
1.61 1.43e-02 GO:0031175 neuron projection development
1.51 1.52e-02 GO:0030182 neuron differentiation
2.38 1.78e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.45 1.81e-02 GO:0048699 generation of neurons
4.88 1.83e-02 GO:0031114 regulation of microtubule depolymerization
1.36 2.08e-02 GO:0002376 immune system process
2.21 2.53e-02 GO:0051969 regulation of transmission of nerve impulse
1.73 2.57e-02 GO:0007411 axon guidance
2.41 2.95e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.67 2.99e-02 GO:0006163 purine nucleotide metabolic process
1.64 3.09e-02 GO:0007409 axonogenesis
1.99 3.64e-02 GO:0002757 immune response-activating signal transduction
1.54 3.90e-02 GO:0048666 neuron development
2.29 4.08e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.74 4.45e-02 GO:0006140 regulation of nucleotide metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.94e-11 GO:0005737 cytoplasm
1.10 3.07e-09 GO:0005622 intracellular
1.11 9.46e-09 GO:0044424 intracellular part
2.31 6.02e-06 GO:0030424 axon
1.82 1.64e-05 GO:0043005 neuron projection
1.15 1.71e-04 GO:0044444 cytoplasmic part
1.46 8.41e-04 GO:0042995 cell projection
1.42 1.62e-03 GO:0005794 Golgi apparatus
1.28 1.70e-03 GO:0005829 cytosol
1.63 6.66e-03 GO:0045202 synapse
1.23 2.05e-02 GO:0044459 plasma membrane part
1.63 2.11e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.97 2.06e-09 GO:0060589 nucleoside-triphosphatase regulator activity
1.96 4.62e-09 GO:0030695 GTPase regulator activity
1.16 3.05e-07 GO:0005515 protein binding
2.07 1.23e-06 GO:0005083 small GTPase regulator activity
1.36 1.56e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.35 1.57e-05 GO:0032553 ribonucleotide binding
1.35 1.57e-05 GO:0032555 purine ribonucleotide binding
1.35 2.74e-05 GO:0017076 purine nucleotide binding
1.97 1.93e-04 GO:0005096 GTPase activator activity
1.08 1.94e-04 GO:0005488 binding
1.47 2.79e-04 GO:0030234 enzyme regulator activity
4.31 4.94e-04 GO:0008060 ARF GTPase activator activity
1.47 5.01e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.61 7.30e-04 GO:0008092 cytoskeletal protein binding
1.27 1.15e-03 GO:0000166 nucleotide binding
1.71 1.20e-03 GO:0008047 enzyme activator activity
2.21 1.89e-03 GO:0005516 calmodulin binding
1.48 2.11e-03 GO:0016301 kinase activity
2.09 3.47e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.30 1.29e-02 GO:0032559 adenyl ribonucleotide binding
1.30 1.29e-02 GO:0005524 ATP binding
1.29 1.87e-02 GO:0030554 adenyl nucleotide binding
3.11 2.86e-02 GO:0003823 antigen binding
1.57 2.97e-02 GO:0004674 protein serine/threonine kinase activity
1.43 3.02e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.63 4.26e-02 GO:0035591 signaling adaptor activity