Motif ID: LMO2.p2

Z-value: 1.504


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LMO2chr11_-_33913835,
chr11_-_33891485,
chr11_-_33891258,
chr11_-_33890931		0.228.9e-04Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_13956445 29.669


chr1_+_1981902 23.012 NM_002744
 PRKCZ
protein kinase C, zeta
chr16_+_23847271 22.292 NM_002738
NM_212535
 PRKCB

protein kinase C, beta

chrX_-_13956644 22.029 NM_001001994
 GPM6B
glycoprotein M6B
chr16_+_58497628 21.817 NDRG4
NDRG family member 4
chr16_+_58497993 21.105 NM_001130487
 NDRG4
NDRG family member 4
chrX_-_13956530 21.084 GPM6B
glycoprotein M6B
chr5_+_156693051 20.603 NM_001037333
NM_001037332
 CYFIP2

cytoplasmic FMR1 interacting protein 2

chr7_-_766875 20.261 NM_001164760
 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_+_58497548 20.074 NM_020465
 NDRG4
NDRG family member 4
chr19_+_38755238 19.512 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755097 18.908 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr20_+_44034632 18.294 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
 DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr18_-_74691951 18.263 MBP
myelin basic protein
chr16_+_23847321 17.988 PRKCB
protein kinase C, beta
chr20_+_44035203 17.299 NM_001048223
NM_001048224
 DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr2_+_79740059 16.954 NM_001164883
NM_004389
 CTNNA2

catenin (cadherin-associated protein), alpha 2

chr19_+_38755422 16.764 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr7_-_124405029 16.465 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_65720091 16.243 LOC645195
DNAJC6
uncharacterized LOC645195
DnaJ (Hsp40) homolog, subfamily C, member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
4.88 1.83e-02 GO:0031114 regulation of microtubule depolymerization
4.31 1.90e-03 GO:0032312 regulation of ARF GTPase activity
3.48 2.79e-03 GO:0032012 regulation of ARF protein signal transduction
2.41 2.95e-02 GO:0050851 antigen receptor-mediated signaling pathway
2.38 1.78e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.37 6.69e-03 GO:0050804 regulation of synaptic transmission
2.29 4.08e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.21 2.53e-02 GO:0051969 regulation of transmission of nerve impulse
2.03 3.81e-07 GO:0051056 regulation of small GTPase mediated signal transduction
1.99 3.64e-02 GO:0002757 immune response-activating signal transduction
1.93 4.30e-03 GO:0046578 regulation of Ras protein signal transduction
1.91 1.54e-06 GO:0007268 synaptic transmission
1.87 8.32e-07 GO:0019226 transmission of nerve impulse
1.87 8.32e-07 GO:0035637 multicellular organismal signaling
1.74 4.45e-02 GO:0006140 regulation of nucleotide metabolic process
1.73 2.57e-02 GO:0007411 axon guidance
1.69 5.15e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.68 5.51e-03 GO:0048812 neuron projection morphogenesis
1.67 2.99e-02 GO:0006163 purine nucleotide metabolic process
1.64 3.09e-02 GO:0007409 axonogenesis

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.31 6.02e-06 GO:0030424 axon
1.82 1.64e-05 GO:0043005 neuron projection
1.63 6.66e-03 GO:0045202 synapse
1.63 2.11e-02 GO:0048471 perinuclear region of cytoplasm
1.46 8.41e-04 GO:0042995 cell projection
1.42 1.62e-03 GO:0005794 Golgi apparatus
1.28 1.70e-03 GO:0005829 cytosol
1.23 2.05e-02 GO:0044459 plasma membrane part
1.17 1.94e-11 GO:0005737 cytoplasm
1.15 1.71e-04 GO:0044444 cytoplasmic part
1.11 9.46e-09 GO:0044424 intracellular part
1.10 3.07e-09 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
4.31 4.94e-04 GO:0008060 ARF GTPase activator activity
3.11 2.86e-02 GO:0003823 antigen binding
2.63 4.26e-02 GO:0035591 signaling adaptor activity
2.21 1.89e-03 GO:0005516 calmodulin binding
2.09 3.47e-03 GO:0005085 guanyl-nucleotide exchange factor activity
2.07 1.23e-06 GO:0005083 small GTPase regulator activity
1.97 2.06e-09 GO:0060589 nucleoside-triphosphatase regulator activity
1.97 1.93e-04 GO:0005096 GTPase activator activity
1.96 4.62e-09 GO:0030695 GTPase regulator activity
1.71 1.20e-03 GO:0008047 enzyme activator activity
1.61 7.30e-04 GO:0008092 cytoskeletal protein binding
1.57 2.97e-02 GO:0004674 protein serine/threonine kinase activity
1.48 2.11e-03 GO:0016301 kinase activity
1.47 2.79e-04 GO:0030234 enzyme regulator activity
1.47 5.01e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.43 3.02e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.36 1.56e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.35 1.57e-05 GO:0032553 ribonucleotide binding
1.35 1.57e-05 GO:0032555 purine ribonucleotide binding
1.35 2.74e-05 GO:0017076 purine nucleotide binding