Motif ID: MAFB.p2

Z-value: 2.331


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_39317875-0.009.9e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_60337350 63.758 NM_021136
 RTN1
reticulon 1
chr14_+_90863365 32.829 CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr20_-_35374530 27.541 NM_022477
NM_032013
 NDRG3

NDRG family member 3

chr2_+_30369868 26.690 YPEL5
yippee-like 5 (Drosophila)
chr2_+_30369800 26.201 YPEL5
yippee-like 5 (Drosophila)
chr2_+_30369749 25.285 NM_001127399
NM_001127400
NM_001127401
NM_016061
 YPEL5



yippee-like 5 (Drosophila)



chr13_+_98086315 23.340 NM_021033
 RAP2A
RAP2A, member of RAS oncogene family
chr2_+_114647683 22.447 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr6_+_107811272 21.981 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chr1_+_44870926 21.953 NM_018150
 RNF220
ring finger protein 220
chr8_+_24771276 21.829 NEFM
neurofilament, medium polypeptide
chr10_+_111765725 21.680 NM_019903
 ADD3
adducin 3 (gamma)
chr19_+_36359346 21.666 NM_001024807
NM_005166
 APLP1

amyloid beta (A4) precursor-like protein 1

chr16_+_2039945 20.684 NM_004209
 SYNGR3
synaptogyrin 3
chr1_+_87794576 20.250 LMO4
LIM domain only 4
chr2_-_55277421 20.027 RTN4
reticulon 4
chr8_+_104152876 20.027 NM_001024372
NM_024812
 BAALC

brain and acute leukemia, cytoplasmic

chr8_+_24771268 19.549 NM_005382
 NEFM
neurofilament, medium polypeptide
chr14_-_60097531 19.255 NM_206852
 RTN1
reticulon 1
chr2_+_231729661 19.163 ITM2C
integral membrane protein 2C

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 242 entries
enrichment   p-value GO term description
4.15 2.48e-02 GO:0035336 long-chain fatty-acyl-CoA metabolic process
4.15 2.48e-02 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
2.90 1.17e-03 GO:0006521 regulation of cellular amino acid metabolic process
2.60 5.08e-03 GO:0033238 regulation of cellular amine metabolic process
2.51 7.47e-08 GO:0006184 GTP catabolic process
2.50 5.59e-13 GO:0009154 purine ribonucleotide catabolic process
2.49 1.89e-12 GO:0009203 ribonucleoside triphosphate catabolic process
2.49 1.89e-12 GO:0009207 purine ribonucleoside triphosphate catabolic process
2.48 1.07e-12 GO:0009261 ribonucleotide catabolic process
2.48 2.62e-12 GO:0009146 purine nucleoside triphosphate catabolic process
2.47 1.97e-12 GO:0009143 nucleoside triphosphate catabolic process
2.45 1.95e-02 GO:0006200 ATP catabolic process
2.44 1.11e-07 GO:0046039 GTP metabolic process
2.43 1.37e-03 GO:0031397 negative regulation of protein ubiquitination
2.42 3.34e-03 GO:0051351 positive regulation of ligase activity
2.40 2.97e-12 GO:0006195 purine nucleotide catabolic process
2.38 8.26e-15 GO:0009199 ribonucleoside triphosphate metabolic process
2.38 1.10e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.38 3.61e-02 GO:0051352 negative regulation of ligase activity
2.38 3.61e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 20 of 69 entries
enrichment   p-value GO term description
2.85 3.28e-05 GO:0000502 proteasome complex
2.72 1.10e-04 GO:0030427 site of polarized growth
2.71 2.07e-04 GO:0030426 growth cone
2.68 2.09e-02 GO:0016469 proton-transporting two-sector ATPase complex
2.46 2.04e-05 GO:0019717 synaptosome
2.45 9.57e-04 GO:0033267 axon part
2.35 8.89e-06 GO:0044455 mitochondrial membrane part
2.33 7.27e-04 GO:0016585 chromatin remodeling complex
2.23 3.98e-03 GO:0042470 melanosome
2.23 3.98e-03 GO:0048770 pigment granule
2.15 1.84e-06 GO:0030424 axon
1.91 1.46e-02 GO:0005681 spliceosomal complex
1.87 1.49e-04 GO:0016604 nuclear body
1.81 4.93e-03 GO:0030425 dendrite
1.78 1.02e-05 GO:0005625 soluble fraction
1.76 1.28e-06 GO:0043005 neuron projection
1.71 3.08e-03 GO:0010008 endosome membrane
1.70 1.15e-05 GO:0045202 synapse
1.70 4.12e-03 GO:0044440 endosomal part
1.67 2.69e-04 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
2.51 2.07e-03 GO:0042625 ATPase activity, coupled to transmembrane movement of ions
2.44 3.94e-03 GO:0008017 microtubule binding
2.26 6.94e-03 GO:0008565 protein transporter activity
2.19 7.77e-04 GO:0015631 tubulin binding
2.15 1.54e-07 GO:0003924 GTPase activity
2.00 3.60e-02 GO:0015399 primary active transmembrane transporter activity
2.00 3.60e-02 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity
1.76 2.78e-02 GO:0003682 chromatin binding
1.72 5.10e-05 GO:0005525 GTP binding
1.69 3.81e-06 GO:0016874 ligase activity
1.68 1.23e-04 GO:0019001 guanyl nucleotide binding
1.68 1.23e-04 GO:0032561 guanyl ribonucleotide binding
1.67 2.15e-05 GO:0019904 protein domain specific binding
1.65 1.85e-02 GO:0016881 acid-amino acid ligase activity
1.64 8.75e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.62 3.97e-09 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.61 5.14e-09 GO:0016462 pyrophosphatase activity
1.61 5.81e-09 GO:0016817 hydrolase activity, acting on acid anhydrides
1.61 1.46e-08 GO:0017111 nucleoside-triphosphatase activity
1.61 1.89e-08 GO:0019899 enzyme binding