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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: MAFB.p2

Z-value: 2.331

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_60337350	63.758	NM_021136	RTN1	reticulon 1
chr14_+_90863365	32.829		CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr20_-_35374530	27.541	NM_022477 NM_032013	NDRG3	NDRG family member 3
chr2_+_30369868	26.690		YPEL5	yippee-like 5 (Drosophila)
chr2_+_30369800	26.201		YPEL5	yippee-like 5 (Drosophila)
chr2_+_30369749	25.285	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr13_+_98086315	23.340	NM_021033	RAP2A	RAP2A, member of RAS oncogene family
chr2_+_114647683	22.447		ACTR3	ARP3 actin-related protein 3 homolog (yeast)
chr6_+_107811272	21.981	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr1_+_44870926	21.953	NM_018150	RNF220	ring finger protein 220
chr8_+_24771276	21.829		NEFM	neurofilament, medium polypeptide
chr10_+_111765725	21.680	NM_019903	ADD3	adducin 3 (gamma)
chr19_+_36359346	21.666	NM_001024807 NM_005166	APLP1	amyloid beta (A4) precursor-like protein 1
chr16_+_2039945	20.684	NM_004209	SYNGR3	synaptogyrin 3
chr1_+_87794576	20.250		LMO4	LIM domain only 4
chr2_-_55277421	20.027		RTN4	reticulon 4
chr8_+_104152876	20.027	NM_001024372 NM_024812	BAALC	brain and acute leukemia, cytoplasmic
chr8_+_24771268	19.549	NM_005382	NEFM	neurofilament, medium polypeptide
chr14_-_60097531	19.255	NM_206852	RTN1	reticulon 1
chr2_+_231729661	19.163		ITM2C	integral membrane protein 2C
chr1_-_241520384	18.953		RGS7	regulator of G-protein signaling 7
chr2_+_231729623	18.762		ITM2C	integral membrane protein 2C
chr2_+_114647449	18.582	NM_005721	ACTR3	ARP3 actin-related protein 3 homolog (yeast)
chr2_+_231729501	18.501	NM_001012514 NM_001012516 NM_030926	ITM2C	integral membrane protein 2C
chr11_+_121322848	18.416	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr1_-_241520467	17.932	NM_002924	RGS7	regulator of G-protein signaling 7
chr4_-_74124305	17.473
chr1_+_51701943	16.873	NM_014372	RNF11	ring finger protein 11
chr2_-_55277459	16.674		RTN4	reticulon 4
chr5_+_139493689	16.378	NM_005859	PURA	purine-rich element binding protein A
chr4_-_83350548	16.368		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr1_+_90286595	16.183		LRRC8D	leucine rich repeat containing 8 family, member D
chr22_+_29876180	16.017	NM_021076	NEFH	neurofilament, heavy polypeptide
chr5_+_17217474	15.311	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr1_+_51701995	15.291		RNF11	ring finger protein 11
chr1_+_51701970	14.918		RNF11	ring finger protein 11
chrX_-_154688260	14.798	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chrX_+_40440229	14.761		ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2
chr14_-_60097314	14.656		RTN1	reticulon 1
chr20_-_34330093	14.521		RBM39	RNA binding motif protein 39
chr1_-_32403975	14.507	NM_080391	PTP4A2	protein tyrosine phosphatase type IVA, member 2
chr1_+_90286469	14.120	NM_001134479	LRRC8D	leucine rich repeat containing 8 family, member D
chr1_+_110527307	14.111		AHCYL1	adenosylhomocysteinase-like 1
chr6_+_150070844	13.998		PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr8_-_101964236	13.936		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr2_+_231729638	13.919		ITM2C	integral membrane protein 2C
chr5_-_11904127	13.871		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr1_-_32403888	13.871		PTP4A2	protein tyrosine phosphatase type IVA, member 2
chr20_-_35374468	13.815		NDRG3	NDRG family member 3
chrX_+_40440145	13.738	NM_005765	ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2
chr1_+_87794150	13.595	NM_006769	LMO4	LIM domain only 4
chr4_-_83350829	13.406		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr6_+_150070818	13.197	NM_001252049 NM_001252050 NM_001252051 NM_001252052 NM_001252053 NM_005389	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr2_+_191745546	13.153	NM_014905	GLS	glutaminase
chr1_+_110527399	13.135		AHCYL1	adenosylhomocysteinase-like 1
chr1_+_110527327	13.112	NM_001242673 NM_006621	AHCYL1	adenosylhomocysteinase-like 1
chrX_+_154114609	13.062	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr6_+_150070856	13.020		PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr11_+_63448868	12.986	NM_006054 NM_201428 NM_201429 NM_201430	RTN3	reticulon 3
chr2_+_114647699	12.948		ACTR3	ARP3 actin-related protein 3 homolog (yeast)
chr2_+_191745791	12.894		GLS	glutaminase
chrX_-_13835187	12.883		GPM6B	glycoprotein M6B
chrX_+_40440261	12.847		ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2
chr8_-_101964248	12.818		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964197	12.739		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964247	12.699		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_-_101964268	12.575		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr4_+_158141735	12.498	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chrX_-_47479229	12.296	NM_006950 NM_133499	SYN1	synapsin I
chr20_-_34329872	12.257		RBM39	RNA binding motif protein 39
chr1_+_110527418	12.194		AHCYL1	adenosylhomocysteinase-like 1
chr4_-_83350452	12.123		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr1_+_110527432	12.097		AHCYL1	adenosylhomocysteinase-like 1
chr14_-_60097223	12.002		RTN1	reticulon 1
chr8_-_101964258	11.998		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr14_-_23821423	11.850	NM_020372	SLC22A17	solute carrier family 22, member 17
chr3_-_10547340	11.758		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr19_-_59069747	11.707		UBE2M	ubiquitin-conjugating enzyme E2M
chr2_-_74601653	11.706	NM_001135041 NM_023019	DCTN1	dynactin 1
chr2_-_55277592	11.578		RTN4	reticulon 4
chr2_-_55277620	11.563		RTN4	reticulon 4
chr4_+_166299942	11.463	NM_001873	CPE	carboxypeptidase E
chr7_-_150754934	11.407		CDK5	cyclin-dependent kinase 5
chr11_-_10830452	11.364		EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr11_+_65658101	11.274		CCDC85B	coiled-coil domain containing 85B
chr4_+_166128769	11.099	NM_007246	KLHL2	kelch-like 2, Mayven (Drosophila)
chrX_-_48693934	11.098	NM_013271	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor
chr1_-_21503352	11.023	NM_001198801 NM_001198802	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr6_-_75994477	11.010		TMEM30A	transmembrane protein 30A
chr20_+_43514350	10.985		YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr20_-_32699915	10.980		EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr7_-_150754979	10.873	NM_001164410 NM_004935	CDK5	cyclin-dependent kinase 5
chr12_+_7023490	10.833	NM_001975	ENO2	enolase 2 (gamma, neuronal)
chr6_-_75994496	10.720		TMEM30A	transmembrane protein 30A
chr2_+_114647663	10.650		ACTR3	ARP3 actin-related protein 3 homolog (yeast)
chr14_-_23822025	10.626	NM_016609	SLC22A17	solute carrier family 22, member 17
chr1_-_177133818	10.513		ASTN1	astrotactin 1
chr1_-_21503304	10.463		EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr1_+_87794548	10.454		LMO4	LIM domain only 4
chr3_-_33481862	10.415	NM_001128160 NM_014517	UBP1	upstream binding protein 1 (LBP-1a)
chr17_+_34901498	10.373		GGNBP2	gametogenetin binding protein 2
chr14_+_90863302	10.364	NM_006888	CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr7_-_124405029	10.271		GPR37	G protein-coupled receptor 37 (endothelin receptor type B-like)
chr13_+_98086681	10.193		RAP2A	RAP2A, member of RAS oncogene family
chr7_+_106685007	10.120	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr11_-_10879365	10.116	NM_001143667 NM_021211	ZBED5	zinc finger, BED-type containing 5
chr10_-_75255718	10.065		PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr10_-_75634219	10.017	NM_001204492 NM_001222 NM_172169 NM_172170 NM_172171 NM_172173	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma
chr11_-_10830299	9.941		EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr8_-_101964334	9.894	NM_145690	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chrX_-_13835313	9.827	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr6_+_71377471	9.818	NM_001044305 NM_021940	SMAP1	small ArfGAP 1
chr20_+_1246959	9.816	NM_014723	SNPH	syntaphilin
chrX_-_13835012	9.807		GPM6B	glycoprotein M6B
chr1_+_50574589	9.801	NM_001144774 NM_021952	ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chrX_+_119005789	9.750		NDUFA1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
chr6_+_71377584	9.717		SMAP1	small ArfGAP 1
chr22_+_32340592	9.694		YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr20_+_57466509	9.669		GNAS	GNAS complex locus
chr2_-_55277653	9.651		RTN4	reticulon 4
chr4_-_15656944	9.612		FBXL5	F-box and leucine-rich repeat protein 5
chr6_-_38670915	9.610		GLO1	glyoxalase I
chr5_+_17217781	9.515		BASP1	brain abundant, membrane attached signal protein 1
chr5_+_140346053	9.444		PCDHAC2	protocadherin alpha subfamily C, 2
chr7_-_150945731	9.438	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr8_+_85095702	9.418		RALYL	RALY RNA binding protein-like
chr6_-_75994631	9.405	NM_001143958 NM_018247	TMEM30A	transmembrane protein 30A
chr7_+_95401817	9.380	NM_001135556 NM_001135557 NM_004411	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1
chr2_+_198380752	9.299	NM_001100819 NM_015387	MOB4	MOB family member 4, phocein
chr10_-_73848263	9.290		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr9_-_101470836	9.246	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr9_+_131451847	9.230		SET	SET nuclear oncogene
chr12_+_62860816	9.167		MON2	MON2 homolog (S. cerevisiae)
chr1_+_84944919	9.100	NM_025065	RPF1	ribosome production factor 1 homolog (S. cerevisiae)
chr6_-_38670922	9.031	NM_006708	GLO1	glyoxalase I
chr15_-_59225766	9.011		SLTM	SAFB-like, transcription modulator
chr6_-_84419018	8.996		SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr10_-_118764559	8.983		KIAA1598	KIAA1598
chrX_+_56589961	8.968	NM_013444	UBQLN2	ubiquilin 2
chrX_-_118827116	8.923		SEPT6	septin 6
chr1_-_245027210	8.921		HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr6_-_38670904	8.915		GLO1	glyoxalase I
chr1_+_111991742	8.891	NM_001688	ATP5F1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr6_-_84418705	8.857	NM_001242792	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr8_+_85095452	8.844	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chr1_-_177133950	8.833	NM_004319 NM_207108	ASTN1	astrotactin 1
chr4_-_74124456	8.781	NM_032217 NM_198889	ANKRD17	ankyrin repeat domain 17
chr2_+_79740171	8.773		CTNNA2	catenin (cadherin-associated protein), alpha 2
chr16_+_103892	8.766		SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr7_-_140179333	8.763	NM_001145125 NM_013446	MKRN1	makorin ring finger protein 1
chr8_-_102803196	8.702		NCALD	neurocalcin delta
chr1_-_3713048	8.605	NM_020710	LRRC47	leucine rich repeat containing 47
chr3_-_18466759	8.602	NM_001195470 NM_002971	SATB1	SATB homeobox 1
chr1_+_50574601	8.445		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_+_103827	8.421	NM_024571	SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)
chr6_-_38670871	8.421		GLO1	glyoxalase I
chr20_-_34330177	8.379		RBM39	RNA binding motif protein 39
chr1_+_87170222	8.364	NM_001206651 NM_001206652 NM_001206653 NM_016009	SH3GLB1	SH3-domain GRB2-like endophilin B1
chr4_+_166128823	8.336		KLHL2	kelch-like 2, Mayven (Drosophila)
chr4_-_102268333	8.310		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_111767877	8.299		ADD3	adducin 3 (gamma)
chr16_+_23847271	8.155	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr3_-_149688638	8.115	NM_002628 NM_053024	PFN2	profilin 2
chr1_+_10270680	8.114	NM_015074 NM_183416	KIF1B	kinesin family member 1B
chr1_-_245027791	8.102		HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr5_-_88199868	8.086	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chrX_+_51486479	8.076	NM_018094	GSPT2	G1 to S phase transition 2
chr6_-_38670882	8.068		GLO1	glyoxalase I
chr12_-_112819755	8.067	NM_001109662	C12orf51	chromosome 12 open reading frame 51
chr17_+_44101549	8.060		MAPT	microtubule-associated protein tau
chr20_+_57466721	8.055		GNAS	GNAS complex locus
chr3_-_45267068	8.004		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr14_+_29236882	7.982		FOXG1	forkhead box G1
chr1_-_35658731	7.977		SFPQ	splicing factor proline/glutamine-rich
chr7_-_766875	7.931	NM_001164760	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr15_+_80696569	7.914	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr12_-_50297575	7.869	NM_012306	FAIM2	Fas apoptotic inhibitory molecule 2
chr17_+_40610899	7.855		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr8_+_56015013	7.854	NM_052898	XKR4	XK, Kell blood group complex subunit-related family, member 4
chr1_+_109792640	7.834	NM_001408	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr7_-_140179224	7.781		MKRN1	makorin ring finger protein 1
chr11_+_10772781	7.771	NM_014633	CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr2_+_17721806	7.769	NM_003385	VSNL1	visinin-like 1
chr2_+_191745568	7.737		GLS	glutaminase
chr9_-_93405066	7.700	NM_017594	DIRAS2	DIRAS family, GTP-binding RAS-like 2
chrX_+_40944858	7.644	NM_001039590 NM_001039591	USP9X	ubiquitin specific peptidase 9, X-linked
chr8_-_110661007	7.640	NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_017786	SYBU	syntabulin (syntaxin-interacting)
chr4_-_15656974	7.604	NM_001193534 NM_001193535 NM_012161	FBXL5	F-box and leucine-rich repeat protein 5
chr2_+_159313466	7.590	NM_001005476 NM_003628	PKP4	plakophilin 4
chr10_+_111767685	7.583	NM_001121 NM_016824	ADD3	adducin 3 (gamma)
chr8_+_85095501	7.531	NM_173848	RALYL	RALY RNA binding protein-like
chrX_+_153665258	7.390	NM_001493	GDI1	GDP dissociation inhibitor 1
chr20_-_34330179	7.383	NM_001242599 NM_001242600 NM_004902 NM_184234	RBM39	RNA binding motif protein 39
chr1_+_110527701	7.277		AHCYL1	adenosylhomocysteinase-like 1
chr16_+_23847359	7.262		PRKCB	protein kinase C, beta
chr12_-_25403809	7.261		KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr2_-_55277672	7.261		RTN4	reticulon 4
chr17_+_40610915	7.225		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr4_-_15656895	7.202		FBXL5	F-box and leucine-rich repeat protein 5
chr1_-_115053677	7.160		TRIM33	tripartite motif containing 33

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.22	7.19e-56	GO:0009987	cellular process
1.35	2.57e-38	GO:0044237	cellular metabolic process
1.26	3.10e-25	GO:0008152	metabolic process
1.28	7.72e-25	GO:0044238	primary metabolic process
1.37	1.20e-24	GO:0044260	cellular macromolecule metabolic process
1.48	8.29e-20	GO:0044267	cellular protein metabolic process
1.41	2.20e-19	GO:0034641	cellular nitrogen compound metabolic process
1.39	1.25e-18	GO:0006807	nitrogen compound metabolic process
1.44	1.34e-18	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28	2.42e-16	GO:0043170	macromolecule metabolic process
2.35	1.40e-15	GO:0009150	purine ribonucleotide metabolic process
1.64	1.53e-15	GO:0051641	cellular localization
2.31	3.24e-15	GO:0009259	ribonucleotide metabolic process
2.38	8.26e-15	GO:0009199	ribonucleoside triphosphate metabolic process
2.35	1.11e-14	GO:0009141	nucleoside triphosphate metabolic process
1.21	1.42e-14	GO:0050794	regulation of cellular process
2.36	2.01e-14	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.18	2.24e-14	GO:0065007	biological regulation
2.11	3.02e-14	GO:0072521	purine-containing compound metabolic process
2.34	4.83e-14	GO:0009144	purine nucleoside triphosphate metabolic process
1.78	8.96e-14	GO:0046907	intracellular transport
1.19	1.34e-13	GO:0050789	regulation of biological process
1.64	1.85e-13	GO:0051649	establishment of localization in cell
2.13	3.14e-13	GO:0006163	purine nucleotide metabolic process
1.43	5.20e-13	GO:0048523	negative regulation of cellular process
2.50	5.59e-13	GO:0009154	purine ribonucleotide catabolic process
1.32	6.97e-13	GO:0051179	localization
2.48	1.07e-12	GO:0009261	ribonucleotide catabolic process
1.91	1.42e-12	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
2.49	1.89e-12	GO:0009203	ribonucleoside triphosphate catabolic process
2.49	1.89e-12	GO:0009207	purine ribonucleoside triphosphate catabolic process
2.47	1.97e-12	GO:0009143	nucleoside triphosphate catabolic process
2.48	2.62e-12	GO:0009146	purine nucleoside triphosphate catabolic process
2.40	2.97e-12	GO:0006195	purine nucleotide catabolic process
1.40	3.58e-12	GO:0048519	negative regulation of biological process
1.52	4.35e-12	GO:0007399	nervous system development
2.37	5.45e-12	GO:0072523	purine-containing compound catabolic process
1.59	5.82e-12	GO:0044248	cellular catabolic process
1.34	1.14e-11	GO:0019538	protein metabolic process
1.89	1.36e-11	GO:0016071	mRNA metabolic process
1.45	1.87e-11	GO:0006464	protein modification process
1.29	2.57e-11	GO:0023052	signaling
1.91	3.52e-11	GO:0006753	nucleoside phosphate metabolic process
1.91	3.52e-11	GO:0009117	nucleotide metabolic process
2.29	3.98e-11	GO:0009166	nucleotide catabolic process
1.31	4.80e-11	GO:0016043	cellular component organization
1.59	5.89e-11	GO:0008104	protein localization
1.43	6.35e-11	GO:0043412	macromolecule modification
1.30	1.14e-10	GO:0071840	cellular component organization or biogenesis
1.52	1.40e-10	GO:0033036	macromolecule localization
2.20	1.77e-10	GO:0034655	nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
2.20	1.77e-10	GO:0034656	nucleobase, nucleoside and nucleotide catabolic process
1.32	1.79e-10	GO:0051234	establishment of localization
1.49	1.90e-10	GO:0009056	catabolic process
1.59	2.46e-10	GO:0043067	regulation of programmed cell death
1.59	3.21e-10	GO:0042981	regulation of apoptosis
1.32	4.07e-10	GO:0006810	transport
1.58	4.38e-10	GO:0010941	regulation of cell death
1.64	5.60e-10	GO:0045184	establishment of protein localization
2.31	1.05e-09	GO:0048011	nerve growth factor receptor signaling pathway
1.34	1.09e-09	GO:0071842	cellular component organization at cellular level
1.64	1.24e-09	GO:0015031	protein transport
1.58	1.29e-09	GO:0032268	regulation of cellular protein metabolic process
1.63	1.60e-09	GO:0008219	cell death
1.62	2.68e-09	GO:0016265	death
1.32	2.69e-09	GO:0071841	cellular component organization or biogenesis at cellular level
1.83	2.89e-09	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.08	4.56e-09	GO:0046700	heterocycle catabolic process
1.42	4.77e-09	GO:0016070	RNA metabolic process
1.54	5.01e-09	GO:0051246	regulation of protein metabolic process
1.71	6.26e-09	GO:0046483	heterocycle metabolic process
1.34	1.08e-08	GO:0048522	positive regulation of cellular process
2.05	1.11e-08	GO:0044270	cellular nitrogen compound catabolic process
1.82	1.36e-08	GO:0019226	transmission of nerve impulse
1.82	1.36e-08	GO:0035637	multicellular organismal signaling
1.40	1.59e-08	GO:0044281	small molecule metabolic process
1.31	2.54e-08	GO:0048518	positive regulation of biological process
1.27	3.43e-08	GO:0007165	signal transduction
1.85	4.57e-08	GO:0007268	synaptic transmission
1.76	5.50e-08	GO:0044282	small molecule catabolic process
2.51	7.47e-08	GO:0006184	GTP catabolic process
2.44	1.11e-07	GO:0046039	GTP metabolic process
1.86	1.20e-07	GO:0051247	positive regulation of protein metabolic process
1.63	1.36e-07	GO:0012501	programmed cell death
1.34	1.73e-07	GO:0090304	nucleic acid metabolic process
1.66	2.20e-07	GO:0007167	enzyme linked receptor protein signaling pathway
1.62	2.59e-07	GO:0006915	apoptosis
1.74	3.00e-07	GO:0070727	cellular macromolecule localization
1.83	7.64e-07	GO:0006091	generation of precursor metabolites and energy
1.59	7.75e-07	GO:0016192	vesicle-mediated transport
1.72	8.15e-07	GO:0034613	cellular protein localization
1.57	9.13e-07	GO:0031399	regulation of protein modification process
2.00	9.60e-07	GO:0015980	energy derivation by oxidation of organic compounds
1.22	1.11e-06	GO:0051716	cellular response to stimulus
1.91	1.79e-06	GO:0006511	ubiquitin-dependent protein catabolic process
1.82	1.80e-06	GO:0032270	positive regulation of cellular protein metabolic process
1.35	2.05e-06	GO:0010467	gene expression
1.87	2.45e-06	GO:0044257	cellular protein catabolic process
1.49	2.50e-06	GO:0006793	phosphorus metabolic process
1.49	2.50e-06	GO:0006796	phosphate metabolic process
1.88	2.73e-06	GO:0070647	protein modification by small protein conjugation or removal
1.69	3.06e-06	GO:0044265	cellular macromolecule catabolic process
1.88	3.39e-06	GO:0043632	modification-dependent macromolecule catabolic process
1.66	3.78e-06	GO:0048666	neuron development
1.83	4.50e-06	GO:0030163	protein catabolic process
1.87	5.44e-06	GO:0019941	modification-dependent protein catabolic process
1.70	5.44e-06	GO:0031175	neuron projection development
1.61	5.66e-06	GO:0006396	RNA processing
1.36	8.14e-06	GO:0023051	regulation of signaling
1.85	9.94e-06	GO:0051603	proteolysis involved in cellular protein catabolic process
1.77	1.24e-05	GO:0006886	intracellular protein transport
1.40	1.28e-05	GO:0035556	intracellular signal transduction
1.49	1.28e-05	GO:0022008	neurogenesis
1.77	1.40e-05	GO:0006397	mRNA processing
1.87	1.61e-05	GO:0008380	RNA splicing
1.47	1.67e-05	GO:0009892	negative regulation of metabolic process
1.59	1.99e-05	GO:0051726	regulation of cell cycle
1.50	2.23e-05	GO:0048699	generation of neurons
1.86	2.31e-05	GO:0031401	positive regulation of protein modification process
1.48	2.53e-05	GO:0031324	negative regulation of cellular metabolic process
1.58	3.20e-05	GO:0030030	cell projection organization
2.19	3.31e-05	GO:0031400	negative regulation of protein modification process
1.48	3.66e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.89	3.69e-05	GO:0032446	protein modification by small protein conjugation
1.64	3.87e-05	GO:0044092	negative regulation of molecular function
1.47	4.32e-05	GO:0048468	cell development
1.58	5.35e-05	GO:0009057	macromolecule catabolic process
1.27	6.02e-05	GO:0044249	cellular biosynthetic process
1.74	6.17e-05	GO:0007264	small GTPase mediated signal transduction
1.54	6.36e-05	GO:0030182	neuron differentiation
2.23	6.56e-05	GO:0031396	regulation of protein ubiquitination
1.41	9.04e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.67	1.14e-04	GO:0048812	neuron projection morphogenesis
1.33	1.19e-04	GO:0006996	organelle organization
1.28	1.21e-04	GO:0065008	regulation of biological quality
2.27	1.27e-04	GO:0046034	ATP metabolic process
1.91	1.66e-04	GO:0032269	negative regulation of cellular protein metabolic process
1.67	1.69e-04	GO:0048667	cell morphogenesis involved in neuron differentiation
1.42	1.71e-04	GO:0022607	cellular component assembly
1.35	1.84e-04	GO:0065009	regulation of molecular function
1.89	1.95e-04	GO:0051248	negative regulation of protein metabolic process
1.85	2.41e-04	GO:0007346	regulation of mitotic cell cycle
1.41	2.62e-04	GO:0010646	regulation of cell communication
1.47	2.66e-04	GO:0051128	regulation of cellular component organization
1.92	2.72e-04	GO:0051129	negative regulation of cellular component organization
1.25	2.77e-04	GO:0009058	biosynthetic process
1.23	2.80e-04	GO:0048731	system development
1.67	3.67e-04	GO:0007409	axonogenesis
1.19	4.06e-04	GO:0019222	regulation of metabolic process
1.36	5.16e-04	GO:0009893	positive regulation of metabolic process
1.60	5.58e-04	GO:0000904	cell morphogenesis involved in differentiation
1.20	5.63e-04	GO:0031323	regulation of cellular metabolic process
2.32	5.74e-04	GO:0031398	positive regulation of protein ubiquitination
1.37	6.28e-04	GO:0044085	cellular component biogenesis
1.64	8.15e-04	GO:0043086	negative regulation of catalytic activity
2.21	9.01e-04	GO:0045333	cellular respiration
1.82	1.07e-03	GO:0016567	protein ubiquitination
2.90	1.17e-03	GO:0006521	regulation of cellular amino acid metabolic process
1.58	1.29e-03	GO:0032990	cell part morphogenesis
2.43	1.37e-03	GO:0031397	negative regulation of protein ubiquitination
1.58	1.47e-03	GO:0048858	cell projection morphogenesis
1.66	2.20e-03	GO:0044271	cellular nitrogen compound biosynthetic process
1.20	2.68e-03	GO:0048856	anatomical structure development
1.43	2.81e-03	GO:0016310	phosphorylation
1.89	2.82e-03	GO:0000375	RNA splicing, via transesterification reactions
1.92	2.87e-03	GO:0034404	nucleobase, nucleoside and nucleotide biosynthetic process
1.92	2.87e-03	GO:0034654	nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
1.70	2.94e-03	GO:0033043	regulation of organelle organization
1.47	2.99e-03	GO:0065003	macromolecular complex assembly
1.19	3.26e-03	GO:0060255	regulation of macromolecule metabolic process
2.42	3.34e-03	GO:0051351	positive regulation of ligase activity
2.32	3.36e-03	GO:0009152	purine ribonucleotide biosynthetic process
2.32	3.36e-03	GO:0051340	regulation of ligase activity
2.07	3.40e-03	GO:0072522	purine-containing compound biosynthetic process
1.35	3.55e-03	GO:0050790	regulation of catalytic activity
2.00	3.78e-03	GO:0010498	proteasomal protein catabolic process
2.00	3.78e-03	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.87	4.07e-03	GO:0006605	protein targeting
1.46	4.20e-03	GO:0019220	regulation of phosphate metabolic process
1.46	4.20e-03	GO:0051174	regulation of phosphorus metabolic process
2.24	4.21e-03	GO:0009260	ribonucleotide biosynthetic process
1.88	4.53e-03	GO:0006457	protein folding
2.60	5.08e-03	GO:0033238	regulation of cellular amine metabolic process
1.34	5.08e-03	GO:0031325	positive regulation of cellular metabolic process
1.68	5.17e-03	GO:0032535	regulation of cellular component size
1.67	5.94e-03	GO:0007411	axon guidance
1.88	6.06e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.88	6.06e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
1.43	7.55e-03	GO:0071844	cellular component assembly at cellular level
1.18	9.29e-03	GO:0080090	regulation of primary metabolic process
1.93	9.41e-03	GO:0009165	nucleotide biosynthetic process
1.63	1.04e-02	GO:0012502	induction of programmed cell death
1.62	1.04e-02	GO:0016568	chromatin modification
2.28	1.07e-02	GO:0051438	regulation of ubiquitin-protein ligase activity
2.38	1.10e-02	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.49	1.13e-02	GO:0050878	regulation of body fluid levels
1.42	1.13e-02	GO:0007267	cell-cell signaling
1.53	1.20e-02	GO:0007596	blood coagulation
1.53	1.20e-02	GO:0050817	coagulation
1.52	1.26e-02	GO:0043068	positive regulation of programmed cell death
1.71	1.32e-02	GO:0010608	posttranscriptional regulation of gene expression
1.48	1.37e-02	GO:0000902	cell morphogenesis
2.05	1.42e-02	GO:0006164	purine nucleotide biosynthetic process
1.89	1.49e-02	GO:0006913	nucleocytoplasmic transport
1.89	1.49e-02	GO:0032869	cellular response to insulin stimulus
1.52	1.65e-02	GO:0007599	hemostasis
1.50	1.69e-02	GO:0010942	positive regulation of cell death
1.22	1.70e-02	GO:0006950	response to stress
1.26	1.72e-02	GO:0007166	cell surface receptor linked signaling pathway
1.61	1.73e-02	GO:0044419	interspecies interaction between organisms
1.62	1.73e-02	GO:0006917	induction of apoptosis
2.23	1.83e-02	GO:0022904	respiratory electron transport chain
2.45	1.95e-02	GO:0006200	ATP catabolic process
1.86	2.15e-02	GO:0051169	nuclear transport
1.52	2.24e-02	GO:0006325	chromatin organization
1.43	2.45e-02	GO:0042325	regulation of phosphorylation
4.15	2.48e-02	GO:0035336	long-chain fatty-acyl-CoA metabolic process
4.15	2.48e-02	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
1.99	2.48e-02	GO:0048193	Golgi vesicle transport
2.33	2.67e-02	GO:0009142	nucleoside triphosphate biosynthetic process
1.50	2.72e-02	GO:0043065	positive regulation of apoptosis
2.02	2.96e-02	GO:0007093	mitotic cell cycle checkpoint
1.23	3.08e-02	GO:0030154	cell differentiation
1.54	3.09e-02	GO:0043069	negative regulation of programmed cell death
1.50	3.22e-02	GO:0070271	protein complex biogenesis
1.75	3.23e-02	GO:0071375	cellular response to peptide hormone stimulus
2.27	3.46e-02	GO:2000045	regulation of G1/S transition of mitotic cell cycle
2.05	3.50e-02	GO:0043254	regulation of protein complex assembly
1.53	3.50e-02	GO:0043066	negative regulation of apoptosis
2.34	3.60e-02	GO:0032271	regulation of protein polymerization
2.38	3.61e-02	GO:0051352	negative regulation of ligase activity
2.38	3.61e-02	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.52	3.70e-02	GO:0060548	negative regulation of cell death
1.28	3.84e-02	GO:0009966	regulation of signal transduction
1.58	4.03e-02	GO:0090066	regulation of anatomical structure size
1.50	4.04e-02	GO:0006461	protein complex assembly
1.45	4.22e-02	GO:0042060	wound healing
1.37	4.40e-02	GO:0043933	macromolecular complex subunit organization
1.43	4.63e-02	GO:0032989	cellular component morphogenesis
1.49	4.72e-02	GO:0044283	small molecule biosynthetic process
1.60	4.74e-02	GO:0071495	cellular response to endogenous stimulus
2.31	4.79e-02	GO:0009201	ribonucleoside triphosphate biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.30	1.09e-51	GO:0005737	cytoplasm
1.19	1.05e-45	GO:0005622	intracellular
1.19	4.68e-45	GO:0044424	intracellular part
1.33	3.21e-33	GO:0044444	cytoplasmic part
1.20	7.15e-24	GO:0043227	membrane-bounded organelle
1.20	1.49e-23	GO:0043231	intracellular membrane-bounded organelle
1.17	5.41e-23	GO:0043226	organelle
1.17	7.00e-23	GO:0043229	intracellular organelle
1.54	1.37e-21	GO:0005829	cytosol
1.38	1.63e-20	GO:0032991	macromolecular complex
1.42	3.52e-20	GO:0043234	protein complex
1.27	6.94e-20	GO:0044446	intracellular organelle part
1.27	1.34e-19	GO:0044422	organelle part
1.06	2.23e-12	GO:0044464	cell part
1.06	2.39e-12	GO:0005623	cell
1.37	1.56e-10	GO:0044428	nuclear part
1.19	6.32e-09	GO:0005634	nucleus
1.32	8.77e-08	GO:0070013	intracellular organelle lumen
1.31	1.09e-07	GO:0031974	membrane-enclosed lumen
1.32	2.41e-07	GO:0031090	organelle membrane
1.30	3.22e-07	GO:0043233	organelle lumen
1.34	6.58e-07	GO:0031981	nuclear lumen
1.40	1.21e-06	GO:0005654	nucleoplasm
1.76	1.28e-06	GO:0043005	neuron projection
1.43	1.71e-06	GO:0000267	cell fraction
2.15	1.84e-06	GO:0030424	axon
1.53	5.31e-06	GO:0016023	cytoplasmic membrane-bounded vesicle
1.52	7.04e-06	GO:0031988	membrane-bounded vesicle
2.35	8.89e-06	GO:0044455	mitochondrial membrane part
1.78	1.02e-05	GO:0005625	soluble fraction
1.70	1.15e-05	GO:0045202	synapse
1.66	1.69e-05	GO:0005768	endosome
1.49	1.81e-05	GO:0031410	cytoplasmic vesicle
2.46	2.04e-05	GO:0019717	synaptosome
1.48	2.42e-05	GO:0031982	vesicle
2.85	3.28e-05	GO:0000502	proteasome complex
1.50	4.55e-05	GO:0031967	organelle envelope
1.41	8.21e-05	GO:0005794	Golgi apparatus
1.48	8.95e-05	GO:0031975	envelope
2.72	1.10e-04	GO:0030427	site of polarized growth
1.53	1.42e-04	GO:0044431	Golgi apparatus part
1.87	1.49e-04	GO:0016604	nuclear body
2.71	2.07e-04	GO:0030426	growth cone
1.67	2.69e-04	GO:0048471	perinuclear region of cytoplasm
1.57	3.39e-04	GO:0000139	Golgi membrane
1.45	5.54e-04	GO:0044451	nucleoplasm part
1.29	5.95e-04	GO:0012505	endomembrane system
2.33	7.27e-04	GO:0016585	chromatin remodeling complex
2.45	9.57e-04	GO:0033267	axon part
1.40	1.28e-03	GO:0005626	insoluble fraction
1.44	1.55e-03	GO:0015630	microtubule cytoskeleton
1.20	2.37e-03	GO:0043228	non-membrane-bounded organelle
1.20	2.37e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.71	3.08e-03	GO:0010008	endosome membrane
2.23	3.98e-03	GO:0042470	melanosome
2.23	3.98e-03	GO:0048770	pigment granule
1.70	4.12e-03	GO:0044440	endosomal part
1.81	4.93e-03	GO:0030425	dendrite
1.37	5.64e-03	GO:0005624	membrane fraction
1.29	6.34e-03	GO:0005739	mitochondrion
1.49	1.12e-02	GO:0005740	mitochondrial envelope
1.91	1.46e-02	GO:0005681	spliceosomal complex
1.48	1.71e-02	GO:0044427	chromosomal part
1.43	1.73e-02	GO:0005694	chromosome
2.68	2.09e-02	GO:0016469	proton-transporting two-sector ATPase complex
1.48	2.30e-02	GO:0031966	mitochondrial membrane
1.61	2.39e-02	GO:0012506	vesicle membrane
1.38	2.39e-02	GO:0044429	mitochondrial part
1.62	2.71e-02	GO:0030659	cytoplasmic vesicle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.38	6.06e-64	GO:0005515	protein binding
1.15	2.59e-30	GO:0005488	binding
1.51	7.34e-22	GO:0000166	nucleotide binding
1.49	1.99e-16	GO:0017076	purine nucleotide binding
1.50	2.14e-16	GO:0032553	ribonucleotide binding
1.50	2.14e-16	GO:0032555	purine ribonucleotide binding
1.49	9.09e-16	GO:0035639	purine ribonucleoside triphosphate binding
1.45	2.67e-10	GO:0030554	adenyl nucleotide binding
1.45	3.47e-10	GO:0032559	adenyl ribonucleotide binding
1.43	2.46e-09	GO:0005524	ATP binding
1.62	3.97e-09	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.61	5.14e-09	GO:0016462	pyrophosphatase activity
1.61	5.81e-09	GO:0016817	hydrolase activity, acting on acid anhydrides
1.19	1.29e-08	GO:0003824	catalytic activity
1.61	1.46e-08	GO:0017111	nucleoside-triphosphatase activity
1.61	1.89e-08	GO:0019899	enzyme binding
1.57	3.51e-08	GO:0003723	RNA binding
2.15	1.54e-07	GO:0003924	GTPase activity
1.69	3.81e-06	GO:0016874	ligase activity
1.67	2.15e-05	GO:0019904	protein domain specific binding
1.59	2.85e-05	GO:0008092	cytoskeletal protein binding
1.72	5.10e-05	GO:0005525	GTP binding
1.68	1.23e-04	GO:0019001	guanyl nucleotide binding
1.68	1.23e-04	GO:0032561	guanyl ribonucleotide binding
2.19	7.77e-04	GO:0015631	tubulin binding
2.51	2.07e-03	GO:0042625	ATPase activity, coupled to transmembrane movement of ions
2.44	3.94e-03	GO:0008017	microtubule binding
2.26	6.94e-03	GO:0008565	protein transporter activity
1.64	8.75e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.57	1.77e-02	GO:0016887	ATPase activity
1.65	1.85e-02	GO:0016881	acid-amino acid ligase activity
1.20	2.18e-02	GO:0016787	hydrolase activity
1.76	2.78e-02	GO:0003682	chromatin binding
2.00	3.60e-02	GO:0015399	primary active transmembrane transporter activity
2.00	3.60e-02	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity