Motif ID: MAZ.p2

Z-value: 1.929


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_29817810-0.491.7e-14Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_113930296 38.010 ZBTB16
zinc finger and BTB domain containing 16
chr11_+_113930430 35.012 NM_006006
 ZBTB16
zinc finger and BTB domain containing 16
chr21_-_45759077 32.978 C21orf2
chromosome 21 open reading frame 2
chr6_-_29600859 31.482 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_29600959 30.179 NM_001470
NM_021904
 GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr16_+_2587989 29.817 PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_+_6845381 28.987 NM_001195563
NM_001242701
NM_015215
 CAMTA1


calmodulin binding transcription activator 1


chr6_-_29595746 28.414 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_+_2588000 27.856 PDPK1
3-phosphoinositide dependent protein kinase-1
chr12_-_6798419 27.339 ZNF384
zinc finger protein 384
chr1_-_15850776 25.605 NM_001229
NM_032996
 CASP9

caspase 9, apoptosis-related cysteine peptidase

chr3_-_13008959 24.352 NM_014869
 IQSEC1
IQ motif and Sec7 domain 1
chr7_+_64498643 24.159 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr7_-_158380360 23.427 NM_002847
NM_130842
NM_130843
 PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr6_-_29600668 22.876 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_29595934 22.780 NM_021903
 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr3_-_132441216 21.890 NPHP3
nephronophthisis 3 (adolescent)
chr4_-_5894695 21.644 NM_001014809
 CRMP1
collapsin response mediator protein 1
chr2_+_10183630 21.362 NM_003597
NM_001177716
 KLF11

Kruppel-like factor 11

chr12_-_6798528 21.357 NM_133476
 ZNF384
zinc finger protein 384

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 320 entries
enrichment   p-value GO term description
2.48 3.61e-04 GO:0048639 positive regulation of developmental growth
2.00 1.67e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.93 7.13e-04 GO:0048638 regulation of developmental growth
1.87 2.08e-02 GO:0043279 response to alkaloid
1.81 1.45e-04 GO:0010720 positive regulation of cell development
1.80 6.14e-03 GO:0050769 positive regulation of neurogenesis
1.80 2.63e-02 GO:0031346 positive regulation of cell projection organization
1.78 4.78e-02 GO:0050770 regulation of axonogenesis
1.77 3.67e-04 GO:0030308 negative regulation of cell growth
1.77 3.98e-03 GO:0001505 regulation of neurotransmitter levels
1.76 3.35e-04 GO:0031098 stress-activated protein kinase signaling cascade
1.74 5.33e-03 GO:0046328 regulation of JNK cascade
1.74 1.26e-02 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.74 2.99e-02 GO:0018205 peptidyl-lysine modification
1.72 1.51e-03 GO:0050796 regulation of insulin secretion
1.71 1.11e-03 GO:0090276 regulation of peptide hormone secretion
1.71 1.23e-03 GO:0045792 negative regulation of cell size
1.71 6.21e-03 GO:0070302 regulation of stress-activated protein kinase signaling cascade
1.68 2.65e-03 GO:0002791 regulation of peptide secretion
1.68 2.65e-03 GO:0090087 regulation of peptide transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 64 entries
enrichment   p-value GO term description
2.42 8.54e-03 GO:0005891 voltage-gated calcium channel complex
2.30 5.64e-03 GO:0005881 cytoplasmic microtubule
2.27 2.88e-03 GO:0034704 calcium channel complex
1.88 1.40e-02 GO:0005905 coated pit
1.71 2.36e-03 GO:0016585 chromatin remodeling complex
1.71 2.85e-02 GO:0042383 sarcolemma
1.66 4.03e-03 GO:0005925 focal adhesion
1.64 2.11e-04 GO:0034703 cation channel complex
1.62 4.95e-02 GO:0008076 voltage-gated potassium channel complex
1.62 4.95e-02 GO:0034705 potassium channel complex
1.60 3.03e-05 GO:0030424 axon
1.58 2.74e-02 GO:0005924 cell-substrate adherens junction
1.55 4.83e-02 GO:0030055 cell-substrate junction
1.53 3.71e-05 GO:0016604 nuclear body
1.48 5.64e-08 GO:0043005 neuron projection
1.45 3.14e-03 GO:0000228 nuclear chromosome
1.44 3.62e-02 GO:0044454 nuclear chromosome part
1.41 2.33e-02 GO:0034702 ion channel complex
1.39 2.70e-04 GO:0048471 perinuclear region of cytoplasm
1.38 3.91e-18 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Showing 1 to 20 of 75 entries
enrichment   p-value GO term description
2.42 1.56e-03 GO:0005245 voltage-gated calcium channel activity
2.11 1.05e-04 GO:0003707 steroid hormone receptor activity
2.05 2.35e-04 GO:0004879 ligand-dependent nuclear receptor activity
1.79 3.23e-03 GO:0005262 calcium channel activity
1.71 5.43e-06 GO:0003714 transcription corepressor activity
1.71 2.39e-02 GO:0031625 ubiquitin protein ligase binding
1.67 2.49e-07 GO:0010843 promoter binding
1.67 7.16e-05 GO:0022843 voltage-gated cation channel activity
1.65 1.20e-02 GO:0005057 receptor signaling protein activity
1.63 9.85e-07 GO:0000975 regulatory region DNA binding
1.63 9.85e-07 GO:0001067 regulatory region nucleic acid binding
1.63 9.85e-07 GO:0044212 transcription regulatory region DNA binding
1.63 2.01e-02 GO:0051427 hormone receptor binding
1.59 7.22e-09 GO:0008134 transcription factor binding
1.58 3.79e-02 GO:0017124 SH3 domain binding
1.56 2.20e-08 GO:0016563 transcription activator activity
1.56 7.84e-03 GO:0004713 protein tyrosine kinase activity
1.55 4.61e-10 GO:0000988 protein binding transcription factor activity
1.55 4.61e-10 GO:0000989 transcription factor binding transcription factor activity
1.55 7.23e-10 GO:0003712 transcription cofactor activity