Motif ID: MSX1,2.p2

Z-value: 1.163


Transcription factors associated with MSX1,2.p2:

Gene SymbolEntrez IDGene Name
MSX1 4487 msh homeobox 1
MSX2 4488 msh homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MSX2chr5_+_1741515310.381.0e-08Click!
MSX1chr4_+_48613710.028.2e-01Click!


Activity profile for motif MSX1,2.p2.

activity profile for motif MSX1,2.p2


Sorted Z-values histogram for motif MSX1,2.p2

Sorted Z-values for motif MSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MSX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_238322840 42.753 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr2_-_238322770 39.764 COL6A3
collagen, type VI, alpha 3
chr2_-_238322815 35.995 COL6A3
collagen, type VI, alpha 3
chr4_+_88896801 30.049 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
 SPP1




secreted phosphoprotein 1




chr4_+_88896838 29.895 SPP1
secreted phosphoprotein 1
chr18_+_21572736 29.010 NM_153211
 TTC39C
tetratricopeptide repeat domain 39C
chr4_+_88896868 28.518 SPP1
secreted phosphoprotein 1
chr4_+_88896899 26.273 SPP1
secreted phosphoprotein 1
chr9_-_116840551 24.839 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_116840460 17.395 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_116840604 15.913 AMBP
alpha-1-microglobulin/bikunin precursor
chr10_+_7745354 14.412 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745325 13.829 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr5_-_160279045 13.632 NM_025153
 ATP10B
ATPase, class V, type 10B
chr5_+_15500288 12.536 NM_012304
 FBXL7
F-box and leucine-rich repeat protein 7
chr16_-_75498582 12.109 NM_145254
 TMEM170A
transmembrane protein 170A
chr17_-_15168590 12.103 NM_000304
 PMP22
peripheral myelin protein 22
chr5_+_140810181 11.404 PCDHGA12
protocadherin gamma subfamily A, 12
chr9_-_116840545 10.332 AMBP
alpha-1-microglobulin/bikunin precursor
chr17_-_66951381 9.566 NM_007168
 ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
6.74 2.57e-03 GO:0007565 female pregnancy
3.69 3.27e-02 GO:0016337 cell-cell adhesion
2.83 3.28e-02 GO:0048666 neuron development
2.69 8.05e-03 GO:0007155 cell adhesion
2.69 8.05e-03 GO:0022610 biological adhesion
2.69 1.84e-02 GO:0030182 neuron differentiation
2.14 2.49e-04 GO:0048583 regulation of response to stimulus
2.05 2.46e-02 GO:0007399 nervous system development
1.77 1.05e-03 GO:0048856 anatomical structure development
1.71 2.14e-02 GO:0048731 system development
1.64 3.05e-03 GO:0032502 developmental process
1.59 4.56e-02 GO:0007275 multicellular organismal development
1.54 8.12e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.76 2.30e-04 GO:0005615 extracellular space
2.66 2.33e-05 GO:0044421 extracellular region part
2.61 7.12e-04 GO:0005626 insoluble fraction
2.50 3.38e-03 GO:0005624 membrane fraction
2.25 2.72e-02 GO:0042995 cell projection
2.06 3.64e-02 GO:0000267 cell fraction
2.04 5.71e-05 GO:0005576 extracellular region
1.98 8.29e-05 GO:0044459 plasma membrane part
1.58 5.87e-04 GO:0071944 cell periphery
1.57 1.24e-03 GO:0005886 plasma membrane

Nothing significant found in function category.