Motif ID: MYBL2.p2

Z-value: 0.997


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBL2chr20_+_42295747-0.228.3e-04Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_71791734 22.312 NUMA1
nuclear mitotic apparatus protein 1
chr10_+_17270257 21.643 NM_003380
 VIM
vimentin
chr11_-_124543598 21.072 NM_170601
 SIAE
sialic acid acetylesterase
chr2_+_143886969 19.070 ARHGAP15
Rho GTPase activating protein 15
chr11_-_64512925 16.939 NM_153819
 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_143886898 16.913 NM_018460
 ARHGAP15
Rho GTPase activating protein 15
chr1_+_198608244 16.553 PTPRC
protein tyrosine phosphatase, receptor type, C
chr10_+_17270469 15.761 VIM
vimentin
chr11_+_71791376 15.266 NM_001145307
NM_001145308
NM_001205138
NM_145309
 LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr11_+_92085261 12.076 NM_001008781
 FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr10_-_28571014 9.771 NM_173496
 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr3_+_122044010 9.343 NM_005213
 CSTA
cystatin A (stefin A)
chr1_-_150780705 9.247 NM_000396
 CTSK
cathepsin K
chr7_+_80267972 8.619 CD36
CD36 molecule (thrombospondin receptor)
chr14_-_21944826 7.902 NM_001163380
 RAB2B
RAB2B, member RAS oncogene family
chr1_+_144614958 6.876 NM_001037675
 NBPF9
NBPF8
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr1_+_198608216 6.657 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_198608136 6.520 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_-_203320249 6.374


chr6_-_32908583 6.055 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
11.01 2.94e-03 GO:0046058 cAMP metabolic process
3.78 1.13e-03 GO:0006936 muscle contraction
3.48 4.14e-03 GO:0003012 muscle system process
3.21 1.31e-02 GO:0055074 calcium ion homeostasis
3.15 3.04e-02 GO:0006874 cellular calcium ion homeostasis
3.10 2.24e-02 GO:0072507 divalent inorganic cation homeostasis
3.05 4.75e-02 GO:0072503 cellular divalent inorganic cation homeostasis
2.13 2.04e-03 GO:0006955 immune response
1.84 2.28e-03 GO:0002376 immune system process
1.59 4.54e-02 GO:0003008 system process
1.57 3.00e-02 GO:0048583 regulation of response to stimulus
1.45 2.34e-03 GO:0007165 signal transduction
1.39 1.21e-02 GO:0023052 signaling
1.34 2.95e-02 GO:0051716 cellular response to stimulus
1.31 8.96e-03 GO:0032501 multicellular organismal process
1.28 3.82e-03 GO:0050896 response to stimulus
1.24 7.01e-03 GO:0050789 regulation of biological process
1.23 3.96e-03 GO:0065007 biological regulation
1.23 2.96e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.69 9.33e-03 GO:0005887 integral to plasma membrane
1.68 8.73e-03 GO:0031226 intrinsic to plasma membrane
1.53 2.33e-03 GO:0044459 plasma membrane part
1.31 1.91e-02 GO:0071944 cell periphery
1.31 1.95e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
14.30 5.16e-03 GO:0030553 cGMP binding
13.10 8.61e-03 GO:0019002 GMP binding
11.79 2.51e-03 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
10.48 1.90e-04 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
10.06 2.71e-04 GO:0004112 cyclic-nucleotide phosphodiesterase activity
5.85 2.20e-02 GO:0008307 structural constituent of muscle
3.93 4.31e-02 GO:0008081 phosphoric diester hydrolase activity