Motif ID: MYFfamily.p2

Z-value: 2.733


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYF5chr12_+_811106890.665.3e-29Click!
MYOD1chr11_+_177411090.622.9e-24Click!
MYF6chr12_+_811014070.586.4e-21Click!
MYOGchr1_-_2030553760.472.0e-13Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_137801178 63.601 NM_001964
EGR1
early growth response 1
chr1_-_57045214 50.183 PPAP2B
phosphatidic acid phosphatase type 2B
chr4_-_57976516 49.111 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57976550 49.068 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chr6_+_99282597 47.833 POU3F2
POU class 3 homeobox 2
chr19_+_33182689 45.349 NM_001105570
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr18_+_21594349 44.292 NM_001135993
NM_001243425
TTC39C

tetratricopeptide repeat domain 39C

chr4_-_57976355 42.453 IGFBP7
insulin-like growth factor binding protein 7
chr6_+_45390284 40.162 RUNX2
runt-related transcription factor 2
chr1_-_57045129 39.031 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_57044980 38.705 PPAP2B
phosphatidic acid phosphatase type 2B
chr6_+_45390376 38.476 RUNX2
runt-related transcription factor 2
chr6_-_91006460 37.314 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr1_-_57045235 37.299 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_66218879 35.956 HMGA2
high mobility group AT-hook 2
chr3_-_195306274 34.921 APOD
apolipoprotein D
chr5_+_137801166 34.102 EGR1
early growth response 1
chr5_-_139422725 33.356 NRG2
neuregulin 2
chr2_+_203499819 32.973 NM_173511
FAM117B
family with sequence similarity 117, member B
chr5_-_178772328 30.762 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr11_+_57365577 29.884 NM_001032295
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr5_+_113698304 29.142 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr16_+_90168671 28.823 FAM157C
family with sequence similarity 157, member C
chr22_+_22712091 27.965 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr1_-_67390413 27.913 NM_024763
NM_207014
WDR78

WD repeat domain 78

chr20_-_23066828 27.413 NM_012072
CD93
CD93 molecule
chr5_-_139422805 26.860 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr6_+_107811272 26.811 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr10_+_124220990 26.458 NM_002775
HTRA1
HtrA serine peptidase 1
chr5_-_178772430 26.453 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chrX_+_21392396 26.084 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr10_+_74451838 25.704 NM_138357
MCU
mitochondrial calcium uniporter
chr14_-_60337350 24.849 NM_021136
RTN1
reticulon 1
chr3_+_111717585 24.789 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr2_+_105471745 24.570 NM_006236
POU3F3
POU class 3 homeobox 3
chr11_-_117747331 23.139 FXYD6
FXYD domain containing ion transport regulator 6
chr2_+_191745568 22.566 GLS
glutaminase
chr17_-_15902907 22.375 NM_001042697
NM_001042698
ZSWIM7

zinc finger, SWIM-type containing 7

chrX_-_107979606 22.266 NM_003604
IRS4
insulin receptor substrate 4
chrX_-_54209639 21.910 NM_017848
NM_198456
FAM120C

family with sequence similarity 120C

chr6_-_91006580 21.889 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr1_+_54519259 21.811 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr15_-_93198602 21.786 NM_207446
FAM174B
family with sequence similarity 174, member B
chr7_-_137531585 21.478 NM_004717
DGKI
diacylglycerol kinase, iota
chr5_+_113698015 21.245 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr8_+_37654757 21.237 GPR124
G protein-coupled receptor 124
chr22_+_33197678 21.137 TIMP3
TIMP metallopeptidase inhibitor 3
chr1_-_59042827 21.131 TACSTD2
tumor-associated calcium signal transducer 2
chr5_-_147162175 20.917 JAKMIP2
janus kinase and microtubule interacting protein 2
chr6_-_32191779 20.652 NM_004557
NOTCH4
notch 4
chr3_-_169381417 20.441 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr19_+_32836500 20.347 NM_001136156
NM_014910
ZNF507

zinc finger protein 507

chrX_-_92928566 20.152 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr10_-_48438975 19.558 NM_004962
GDF10
growth differentiation factor 10
chr2_-_172967627 19.555 DLX2
distal-less homeobox 2
chr9_+_35560424 19.192 RUSC2
RUN and SH3 domain containing 2
chr1_+_11866240 19.179 CLCN6
chloride channel 6
chr10_+_120967094 18.983 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr17_+_14204326 18.927 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr2_-_47797469 18.334 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr3_-_4508939 18.282 SUMF1
sulfatase modifying factor 1
chr3_+_49449753 18.180 TCTA
T-cell leukemia translocation altered gene
chr3_-_120068077 18.164 NM_001099678
LRRC58
leucine rich repeat containing 58
chr19_-_18314731 17.986 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr5_+_140864626 17.981 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr6_+_42897184 17.687 CNPY3
canopy 3 homolog (zebrafish)
chr10_-_90967048 17.600 NM_003956
CH25H
cholesterol 25-hydroxylase
chr2_-_172967234 17.366 NM_004405
DLX2
distal-less homeobox 2
chr12_+_4918341 17.208 NM_002235
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr5_-_147162251 16.979 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr9_+_127539382 16.903 NM_182487
OLFML2A
olfactomedin-like 2A
chr13_-_36050758 16.786 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr1_+_153651050 16.712 NM_000906
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr6_+_41040713 16.626 NFYA
nuclear transcription factor Y, alpha
chr12_+_120427476 16.564 NM_207311
CCDC64
coiled-coil domain containing 64
chr8_-_133492751 16.441 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr5_-_95297424 16.175 ELL2
elongation factor, RNA polymerase II, 2
chr7_+_153749740 16.000 NM_130797
DPP6
dipeptidyl-peptidase 6
chr8_+_24771276 15.982 NEFM
neurofilament, medium polypeptide
chr15_+_96873845 15.908 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_+_49449638 15.701 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr10_+_72163860 15.689 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr11_-_117747618 15.526 NM_001204268
NM_001243598
NM_001164832
NM_001164836
NM_001164837
NM_022003
FXYD6-FXYD2

FXYD6



FXYD6-FXYD2 readthrough

FXYD domain containing ion transport regulator 6



chr1_+_171810611 15.458 NM_001136127
NM_015569
DNM3

dynamin 3

chr2_+_176957448 15.239 NM_000523
HOXD13
homeobox D13
chr1_-_11865963 14.851 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_110513750 14.593 NM_014289
CAPN6
calpain 6
chr9_+_133320093 14.552 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr4_-_39640461 14.512 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr9_+_133320247 14.448 ASS1
argininosuccinate synthase 1
chr1_+_25071906 14.362 CLIC4
chloride intracellular channel 4
chr11_-_66335958 14.283 NM_003793
CTSF
cathepsin F
chr17_+_38599651 14.152 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr8_+_37654395 14.135 NM_032777
GPR124
G protein-coupled receptor 124
chr3_-_129612371 14.114 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr2_-_48982809 14.096 NM_000233
LHCGR
luteinizing hormone/choriogonadotropin receptor
chr2_-_160654668 14.004 CD302
CD302 molecule
chr13_+_113951461 13.897 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr9_+_130548358 13.742 CDK9
cyclin-dependent kinase 9
chr6_+_41040687 13.624 NM_002505
NM_021705
NFYA

nuclear transcription factor Y, alpha

chr8_+_37654833 13.608 GPR124
G protein-coupled receptor 124
chr19_+_41103055 13.546 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr5_-_146258143 13.270 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr12_-_56101667 13.246 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr14_-_27066959 13.169 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr8_+_85095452 13.142 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chr10_+_104678001 13.063 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr2_-_160654736 13.060 NM_001198763
NM_001198764
NM_014880
CD302


CD302 molecule


chr10_-_73848263 13.030 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_11866206 13.017 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr9_-_84304378 12.982 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr14_-_75078669 12.959 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr8_+_37654406 12.947 GPR124
G protein-coupled receptor 124
chr7_-_137028275 12.909 PTN
pleiotrophin
chr2_+_26915390 12.830 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr5_+_140346053 12.830 PCDHAC2
protocadherin alpha subfamily C, 2
chr17_+_40913211 12.821 NM_005854
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr4_+_71570768 12.766 RUFY3
RUN and FYVE domain containing 3
chr19_+_3094266 12.726 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chrX_-_107018889 12.717 TSC22D3
TSC22 domain family, member 3
chr16_-_74641014 12.668 NM_001145666
NM_001145667
NM_012201
GLG1


golgi glycoprotein 1


chr9_-_120177326 12.604 ASTN2
astrotactin 2
chr15_-_53082087 12.598 NM_004498
ONECUT1
one cut homeobox 1
chr6_+_129204285 12.597 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chrX_+_69282340 12.560 NM_207320
OTUD6A
OTU domain containing 6A
chr22_+_23229959 12.530 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr14_+_59104736 12.520 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr17_-_39743085 12.519 NM_000526
KRT14
keratin 14
chr17_-_42200957 12.461 HDAC5
histone deacetylase 5
chr8_+_24771268 12.444 NM_005382
NEFM
neurofilament, medium polypeptide
chr22_+_22676814 12.431


chr8_-_33457491 12.352 DUSP26
dual specificity phosphatase 26 (putative)
chr14_+_29236882 12.283 FOXG1
forkhead box G1
chr9_+_87284625 12.270 NM_001007097
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr12_+_53440809 12.260 NM_198316
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr11_+_113930296 12.256 ZBTB16
zinc finger and BTB domain containing 16
chr2_+_79740059 12.237 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr1_+_209848659 12.183 NM_015714
G0S2
G0/G1switch 2
chr9_+_27109138 12.173 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr22_+_45898690 12.171 NM_001996
NM_006485
NM_006486
NM_006487
FBLN1



fibulin 1



chr20_-_45280059 12.131 NM_001193339
NM_001193342
NM_022829
SLC13A3


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3


chr19_+_13875345 12.120 MRI1
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr19_-_47734215 12.038 NM_014417
BBC3
BCL2 binding component 3
chr2_+_48541767 11.968 NM_002158
FOXN2
forkhead box N2
chr6_+_7727010 11.947 NM_001718
BMP6
bone morphogenetic protein 6
chr1_-_54518790 11.941 TMEM59
transmembrane protein 59
chr20_-_44563684 11.897 FLJ40606
uncharacterized LOC643549
chr21_+_47545896 11.891 COL6A2
collagen, type VI, alpha 2
chr6_-_111136616 11.857 CDK19
cyclin-dependent kinase 19
chr14_-_52535737 11.826 NID2
nidogen 2 (osteonidogen)
chr15_+_99645152 11.819 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr5_+_137774897 11.723 REEP2
receptor accessory protein 2
chr13_-_95364248 11.659 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr7_+_72848108 11.619 NM_003508
FZD9
frizzled family receptor 9
chr10_-_95360959 11.616 NM_006744
RBP4
retinol binding protein 4, plasma
chr19_+_51628136 11.566 NM_001198558
NM_014441
SIGLEC9

sialic acid binding Ig-like lectin 9

chr1_+_47603083 11.539 NM_001010969
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr4_+_71570616 11.458 NM_001130709
RUFY3
RUN and FYVE domain containing 3
chr7_+_158649200 11.438 NM_018051
WDR60
WD repeat domain 60
chr9_+_130548304 11.390 NM_001261
CDK9
cyclin-dependent kinase 9
chr1_+_25071967 11.383 CLIC4
chloride intracellular channel 4
chr11_-_9113092 11.369 NM_001170690
NM_020974
SCUBE2

signal peptide, CUB domain, EGF-like 2

chr2_+_191745791 11.338 GLS
glutaminase
chr3_-_187463474 11.313 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr8_-_133492556 11.272 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr11_+_65837785 11.262 NM_018026
PACS1
phosphofurin acidic cluster sorting protein 1
chr1_-_58716207 11.255 NM_021080
DAB1
disabled homolog 1 (Drosophila)
chr8_-_33457435 11.206 NM_024025
DUSP26
dual specificity phosphatase 26 (putative)
chr10_+_12391728 11.168 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr13_-_114567011 11.157 GAS6
growth arrest-specific 6
chr3_-_73673978 11.126 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr15_+_92937104 11.108 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr16_-_74640915 11.097 GLG1
golgi glycoprotein 1
chr11_-_12030128 11.048 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr22_+_33197744 11.044 TIMP3
TIMP metallopeptidase inhibitor 3
chr12_-_56101465 10.988 ITGA7
integrin, alpha 7
chr6_+_64345672 10.985 PHF3
PHD finger protein 3
chrX_-_140271275 10.952 LDOC1
leucine zipper, down-regulated in cancer 1
chr1_-_200379072 10.948 ZNF281
zinc finger protein 281
chr8_-_27472188 10.935 CLU
clusterin
chr1_+_202317798 10.917 NM_001167857
NM_001167858
NM_002481
PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr2_+_206547352 10.916 NRP2
neuropilin 2
chr16_-_11836602 10.889 NM_015914
TXNDC11
thioredoxin domain containing 11
chrX_-_106960028 10.888 TSC22D3
TSC22 domain family, member 3
chr20_-_23618382 10.883 NM_000099
CST3
cystatin C
chr22_+_21986968 10.880 NM_152612
CCDC116
coiled-coil domain containing 116
chr16_-_68014362 10.867 NM_001129758
NM_022357
DPEP3

dipeptidase 3

chrX_+_110187468 10.800 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr1_-_11866079 10.792 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr6_+_37137882 10.780 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr22_-_18923654 10.760 PRODH
proline dehydrogenase (oxidase) 1
chr19_+_13875299 10.728 NM_001031727
NM_032285
MRI1

methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)

chr1_+_233749749 10.677 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr3_+_111718006 10.621 NM_001008273
TAGLN3
transgelin 3
chr2_+_20646831 10.578 NM_004040
RHOB
ras homolog gene family, member B
chr1_-_38512446 10.510 NM_002699
POU3F1
POU class 3 homeobox 1
chr9_+_124030455 10.499 GSN
gelsolin
chr1_-_32229635 10.485 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr7_+_39990108 10.479 CDK13
cyclin-dependent kinase 13
chr1_-_59248287 10.443 JUN
jun proto-oncogene

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.49 2.72e-38 GO:0023052 signaling
1.47 2.13e-36 GO:0032502 developmental process
1.52 1.18e-34 GO:0048856 anatomical structure development
1.36 3.34e-34 GO:0032501 multicellular organismal process
1.48 2.92e-33 GO:0007275 multicellular organismal development
1.54 3.77e-33 GO:0048731 system development
1.25 1.05e-31 GO:0065007 biological regulation
1.45 1.21e-28 GO:0007165 signal transduction
1.24 2.76e-25 GO:0050789 regulation of biological process
1.60 2.02e-24 GO:0048513 organ development
1.59 2.46e-22 GO:0007166 cell surface receptor linked signaling pathway
1.35 2.46e-22 GO:0051716 cellular response to stimulus
1.24 2.56e-22 GO:0050794 regulation of cellular process
1.14 5.84e-22 GO:0009987 cellular process
1.64 5.04e-21 GO:0007399 nervous system development
1.50 1.03e-20 GO:0042221 response to chemical stimulus
1.25 4.36e-20 GO:0050896 response to stimulus
1.60 1.98e-18 GO:0009653 anatomical structure morphogenesis
1.49 5.70e-18 GO:0048869 cellular developmental process
1.49 8.70e-18 GO:0030154 cell differentiation
1.46 3.56e-16 GO:0065008 regulation of biological quality
1.82 6.22e-16 GO:0007267 cell-cell signaling
1.81 9.72e-16 GO:0007155 cell adhesion
1.81 9.72e-16 GO:0022610 biological adhesion
1.60 2.17e-15 GO:0051239 regulation of multicellular organismal process
1.70 3.41e-14 GO:0050793 regulation of developmental process
1.68 1.45e-13 GO:0022008 neurogenesis
1.68 2.10e-13 GO:0048468 cell development
1.70 2.40e-13 GO:0048699 generation of neurons
1.77 1.64e-12 GO:0030182 neuron differentiation
1.62 2.60e-12 GO:0007154 cell communication
1.55 4.65e-12 GO:0002376 immune system process
1.95 5.09e-12 GO:0051094 positive regulation of developmental process
1.62 8.60e-12 GO:0032879 regulation of localization
1.66 1.14e-11 GO:0040011 locomotion
1.75 1.25e-11 GO:0045595 regulation of cell differentiation
1.89 1.53e-11 GO:0019226 transmission of nerve impulse
1.89 1.53e-11 GO:0035637 multicellular organismal signaling
1.63 2.58e-11 GO:0009611 response to wounding
1.79 2.70e-11 GO:0009887 organ morphogenesis
1.86 3.72e-11 GO:0007417 central nervous system development
1.33 5.44e-11 GO:0048518 positive regulation of biological process
1.41 6.28e-11 GO:0048583 regulation of response to stimulus
1.69 7.28e-11 GO:2000026 regulation of multicellular organismal development
1.79 1.10e-10 GO:0048666 neuron development
2.05 1.39e-10 GO:0045597 positive regulation of cell differentiation
1.44 1.56e-10 GO:0023051 regulation of signaling
1.51 1.91e-10 GO:0010033 response to organic substance
1.58 3.61e-10 GO:0042127 regulation of cell proliferation
2.22 8.86e-10 GO:0030168 platelet activation
1.87 1.79e-09 GO:0007268 synaptic transmission
1.80 2.60e-09 GO:0000904 cell morphogenesis involved in differentiation
1.69 5.31e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.71 7.17e-09 GO:0000902 cell morphogenesis
1.93 7.87e-09 GO:0007420 brain development
1.84 9.54e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.52 1.00e-08 GO:0010646 regulation of cell communication
1.77 2.12e-08 GO:0048858 cell projection morphogenesis
1.75 3.05e-08 GO:0006935 chemotaxis
1.75 3.05e-08 GO:0042330 taxis
1.57 3.18e-08 GO:0009888 tissue development
1.67 3.25e-08 GO:0030030 cell projection organization
1.81 3.52e-08 GO:0048812 neuron projection morphogenesis
1.76 3.84e-08 GO:0001775 cell activation
1.67 3.88e-08 GO:0032989 cellular component morphogenesis
1.75 4.21e-08 GO:0032990 cell part morphogenesis
1.74 1.04e-07 GO:0007599 hemostasis
1.31 1.15e-07 GO:0048522 positive regulation of cellular process
1.74 1.34e-07 GO:0007596 blood coagulation
1.74 1.34e-07 GO:0050817 coagulation
1.67 1.34e-07 GO:0042060 wound healing
1.24 1.99e-07 GO:0051179 localization
1.80 2.04e-07 GO:0007409 axonogenesis
1.73 2.38e-07 GO:0031175 neuron projection development
1.65 2.51e-07 GO:0009725 response to hormone stimulus
1.30 4.29e-07 GO:0048519 negative regulation of biological process
1.73 5.81e-07 GO:0072358 cardiovascular system development
1.73 5.81e-07 GO:0072359 circulatory system development
1.60 7.20e-07 GO:0009719 response to endogenous stimulus
1.51 7.54e-07 GO:0006811 ion transport
1.92 8.20e-07 GO:0019932 second-messenger-mediated signaling
1.56 1.08e-06 GO:0006955 immune response
1.88 1.25e-06 GO:0001501 skeletal system development
1.90 1.53e-06 GO:0016337 cell-cell adhesion
1.39 1.85e-06 GO:0009966 regulation of signal transduction
1.64 1.86e-06 GO:0050878 regulation of body fluid levels
1.53 1.96e-06 GO:0048584 positive regulation of response to stimulus
1.47 2.51e-06 GO:0009605 response to external stimulus
1.91 2.67e-06 GO:0051270 regulation of cellular component movement
2.26 3.68e-06 GO:0019935 cyclic-nucleotide-mediated signaling
1.30 4.02e-06 GO:0048523 negative regulation of cellular process
1.90 4.45e-06 GO:0007423 sensory organ development
1.86 5.11e-06 GO:0022603 regulation of anatomical structure morphogenesis
1.55 6.08e-06 GO:0051049 regulation of transport
1.39 6.54e-06 GO:0035556 intracellular signal transduction
1.83 7.59e-06 GO:0051093 negative regulation of developmental process
2.13 1.29e-05 GO:0030900 forebrain development
2.08 1.31e-05 GO:0048732 gland development
1.63 1.87e-05 GO:0008284 positive regulation of cell proliferation
1.82 2.07e-05 GO:0007610 behavior
1.79 2.73e-05 GO:0007411 axon guidance
1.80 2.80e-05 GO:0060284 regulation of cell development
1.85 2.82e-05 GO:0040012 regulation of locomotion
2.76 4.38e-05 GO:0050770 regulation of axonogenesis
1.84 6.00e-05 GO:0051960 regulation of nervous system development
1.26 6.92e-05 GO:0006950 response to stress
1.89 7.26e-05 GO:0050767 regulation of neurogenesis
1.54 7.36e-05 GO:0001932 regulation of protein phosphorylation
2.12 9.84e-05 GO:0048562 embryonic organ morphogenesis
1.98 1.10e-04 GO:0045664 regulation of neuron differentiation
1.66 1.42e-04 GO:0016477 cell migration
1.85 1.44e-04 GO:0030334 regulation of cell migration
1.82 1.45e-04 GO:0048545 response to steroid hormone stimulus
2.65 1.56e-04 GO:0022612 gland morphogenesis
1.74 1.77e-04 GO:0044057 regulation of system process
1.51 1.91e-04 GO:0042325 regulation of phosphorylation
1.70 1.92e-04 GO:0048598 embryonic morphogenesis
1.58 2.27e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.83 2.54e-04 GO:0045596 negative regulation of cell differentiation
1.83 2.54e-04 GO:2000145 regulation of cell motility
1.51 2.70e-04 GO:0071310 cellular response to organic substance
1.49 2.81e-04 GO:0019220 regulation of phosphate metabolic process
1.49 2.81e-04 GO:0051174 regulation of phosphorus metabolic process
1.78 3.13e-04 GO:0001944 vasculature development
1.42 3.19e-04 GO:0070887 cellular response to chemical stimulus
2.32 3.32e-04 GO:0061138 morphogenesis of a branching epithelium
2.26 4.82e-04 GO:0019933 cAMP-mediated signaling
1.32 4.98e-04 GO:0065009 regulation of molecular function
1.61 5.26e-04 GO:0046903 secretion
1.95 6.13e-04 GO:0048608 reproductive structure development
1.77 6.57e-04 GO:0061061 muscle structure development
1.72 7.00e-04 GO:0051046 regulation of secretion
2.15 7.36e-04 GO:0048705 skeletal system morphogenesis
1.35 7.95e-04 GO:0050790 regulation of catalytic activity
1.61 8.67e-04 GO:0008285 negative regulation of cell proliferation
2.00 8.96e-04 GO:0006936 muscle contraction
2.15 9.46e-04 GO:0001763 morphogenesis of a branching structure
2.06 9.61e-04 GO:0045165 cell fate commitment
3.13 1.07e-03 GO:0009187 cyclic nucleotide metabolic process
1.53 1.14e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
2.43 1.20e-03 GO:0007160 cell-matrix adhesion
2.08 1.61e-03 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger
1.59 1.70e-03 GO:0060341 regulation of cellular localization
2.19 1.95e-03 GO:0043583 ear development
1.50 1.97e-03 GO:0006812 cation transport
1.42 2.15e-03 GO:0051128 regulation of cellular component organization
1.66 2.20e-03 GO:0007389 pattern specification process
1.68 2.29e-03 GO:0051050 positive regulation of transport
1.20 2.33e-03 GO:0006810 transport
1.20 2.49e-03 GO:0051234 establishment of localization
2.29 2.77e-03 GO:0048839 inner ear development
1.97 3.04e-03 GO:0048511 rhythmic process
1.68 3.15e-03 GO:0032940 secretion by cell
1.53 3.23e-03 GO:0048585 negative regulation of response to stimulus
2.08 3.45e-03 GO:0030799 regulation of cyclic nucleotide metabolic process
1.94 3.52e-03 GO:0001934 positive regulation of protein phosphorylation
3.25 3.68e-03 GO:0042733 embryonic digit morphogenesis
1.43 3.80e-03 GO:0006468 protein phosphorylation
2.24 3.95e-03 GO:0031589 cell-substrate adhesion
1.81 4.52e-03 GO:0048514 blood vessel morphogenesis
1.50 4.88e-03 GO:0006928 cellular component movement
1.97 5.07e-03 GO:0001666 response to hypoxia
1.72 5.20e-03 GO:0001568 blood vessel development
2.16 5.59e-03 GO:0048736 appendage development
2.16 5.59e-03 GO:0060173 limb development
2.03 5.59e-03 GO:0060191 regulation of lipase activity
1.87 5.69e-03 GO:0042327 positive regulation of phosphorylation
1.58 5.70e-03 GO:0009968 negative regulation of signal transduction
1.55 5.77e-03 GO:0008283 cell proliferation
1.76 5.86e-03 GO:0007507 heart development
1.55 6.15e-03 GO:0023057 negative regulation of signaling
1.85 6.18e-03 GO:0007517 muscle organ development
1.77 6.30e-03 GO:0048568 embryonic organ development
1.55 6.33e-03 GO:0002684 positive regulation of immune system process
1.90 6.63e-03 GO:0045137 development of primary sexual characteristics
1.55 6.96e-03 GO:0010648 negative regulation of cell communication
2.19 7.00e-03 GO:0031279 regulation of cyclase activity
2.03 7.22e-03 GO:0043627 response to estrogen stimulus
1.92 7.26e-03 GO:0070482 response to oxygen levels
2.05 7.32e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.87 7.32e-03 GO:0003012 muscle system process
2.02 9.15e-03 GO:0001503 ossification
2.04 9.32e-03 GO:0022604 regulation of cell morphogenesis
1.51 9.53e-03 GO:0030001 metal ion transport
2.09 9.55e-03 GO:0060541 respiratory system development
1.84 1.02e-02 GO:0010562 positive regulation of phosphorus metabolic process
1.84 1.02e-02 GO:0045937 positive regulation of phosphate metabolic process
1.62 1.04e-02 GO:0003006 developmental process involved in reproduction
2.17 1.19e-02 GO:0045761 regulation of adenylate cyclase activity
1.53 1.19e-02 GO:0048870 cell motility
1.53 1.19e-02 GO:0051674 localization of cell
2.04 1.20e-02 GO:0030802 regulation of cyclic nucleotide biosynthetic process
2.04 1.20e-02 GO:0030808 regulation of nucleotide biosynthetic process
2.15 1.21e-02 GO:0051339 regulation of lyase activity
3.29 1.23e-02 GO:0061035 regulation of cartilage development
2.10 1.23e-02 GO:0010517 regulation of phospholipase activity
1.25 1.84e-02 GO:0003008 system process
1.50 1.85e-02 GO:0043549 regulation of kinase activity
1.17 1.92e-02 GO:0080090 regulation of primary metabolic process
1.86 2.02e-02 GO:0030155 regulation of cell adhesion
2.13 2.04e-02 GO:0007202 activation of phospholipase C activity
2.08 2.05e-02 GO:0003001 generation of a signal involved in cell-cell signaling
2.08 2.05e-02 GO:0023061 signal release
1.41 2.08e-02 GO:0009790 embryo development
2.31 2.17e-02 GO:0002576 platelet degranulation
1.72 2.21e-02 GO:0003002 regionalization
3.18 2.22e-02 GO:0045778 positive regulation of ossification
1.96 2.28e-02 GO:0007156 homophilic cell adhesion
1.79 2.42e-02 GO:0010817 regulation of hormone levels
1.90 2.49e-02 GO:0008406 gonad development
2.37 2.53e-02 GO:0006937 regulation of muscle contraction
2.13 2.62e-02 GO:0048754 branching morphogenesis of a tube
2.11 2.64e-02 GO:0010863 positive regulation of phospholipase C activity
1.94 2.83e-02 GO:0016055 Wnt receptor signaling pathway
1.37 2.87e-02 GO:0044093 positive regulation of molecular function
2.38 3.20e-02 GO:0042472 inner ear morphogenesis
1.90 3.21e-02 GO:0034330 cell junction organization
2.00 3.23e-02 GO:0002791 regulation of peptide secretion
2.00 3.23e-02 GO:0090087 regulation of peptide transport
2.02 3.30e-02 GO:0030814 regulation of cAMP metabolic process
2.11 3.41e-02 GO:0030323 respiratory tube development
1.40 3.59e-02 GO:0002682 regulation of immune system process
1.47 3.63e-02 GO:0051338 regulation of transferase activity
2.71 3.67e-02 GO:0048663 neuron fate commitment
2.25 3.97e-02 GO:0042471 ear morphogenesis
1.76 4.09e-02 GO:0007548 sex differentiation
1.55 4.10e-02 GO:0060429 epithelium development
2.14 4.35e-02 GO:0030326 embryonic limb morphogenesis
2.14 4.35e-02 GO:0035113 embryonic appendage morphogenesis
2.07 4.39e-02 GO:0035107 appendage morphogenesis
2.07 4.39e-02 GO:0035108 limb morphogenesis
1.55 4.50e-02 GO:0045087 innate immune response
1.33 4.68e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.63 4.81e-02 GO:0035295 tube development
1.15 4.82e-02 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.64 1.21e-35 GO:0044459 plasma membrane part
1.77 1.08e-27 GO:0031226 intrinsic to plasma membrane
1.77 5.94e-27 GO:0005887 integral to plasma membrane
1.36 6.46e-26 GO:0005886 plasma membrane
1.36 1.39e-25 GO:0071944 cell periphery
1.73 8.01e-20 GO:0044421 extracellular region part
1.47 1.40e-17 GO:0005576 extracellular region
2.08 1.88e-14 GO:0031012 extracellular matrix
1.70 2.11e-13 GO:0005615 extracellular space
1.64 5.90e-12 GO:0005626 insoluble fraction
1.53 3.94e-11 GO:0000267 cell fraction
1.62 6.61e-11 GO:0005624 membrane fraction
1.14 1.06e-09 GO:0016020 membrane
1.97 1.35e-09 GO:0005578 proteinaceous extracellular matrix
1.15 2.30e-07 GO:0044425 membrane part
1.56 5.17e-06 GO:0030054 cell junction
2.32 8.98e-06 GO:0044420 extracellular matrix part
1.64 3.05e-05 GO:0045202 synapse
1.86 1.07e-04 GO:0034702 ion channel complex
1.42 1.75e-04 GO:0031982 vesicle
1.13 4.12e-04 GO:0031224 intrinsic to membrane
1.60 4.20e-04 GO:0009986 cell surface
2.75 4.35e-04 GO:0031983 vesicle lumen
1.41 4.92e-04 GO:0031410 cytoplasmic vesicle
1.68 5.20e-04 GO:0044456 synapse part
1.41 7.92e-04 GO:0031988 membrane-bounded vesicle
2.00 9.01e-04 GO:0043235 receptor complex
2.79 9.26e-04 GO:0031093 platelet alpha granule lumen
2.73 1.44e-03 GO:0034774 secretory granule lumen
2.38 1.88e-03 GO:0005604 basement membrane
1.39 2.38e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
2.98 2.51e-03 GO:0005581 collagen
1.76 3.02e-03 GO:0030141 stored secretory granule
2.62 3.30e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
1.12 7.60e-03 GO:0016021 integral to membrane
1.33 9.08e-03 GO:0042995 cell projection
2.41 1.16e-02 GO:0031091 platelet alpha granule
1.77 3.64e-02 GO:0045211 postsynaptic membrane
1.81 3.74e-02 GO:0034703 cation channel complex
2.79 4.09e-02 GO:0042611 MHC protein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 4.72e-12 GO:0005515 protein binding
1.09 1.35e-10 GO:0005488 binding
1.54 2.26e-10 GO:0005102 receptor binding
1.68 3.34e-10 GO:0005509 calcium ion binding
2.67 1.15e-08 GO:0019838 growth factor binding
2.80 3.21e-07 GO:0019199 transmembrane receptor protein kinase activity
1.30 1.13e-06 GO:0004871 signal transducer activity
1.30 1.13e-06 GO:0060089 molecular transducer activity
1.90 1.84e-06 GO:0032403 protein complex binding
1.82 2.39e-06 GO:0022836 gated channel activity
1.71 5.31e-06 GO:0005216 ion channel activity
1.69 6.70e-06 GO:0022838 substrate-specific channel activity
1.52 9.56e-06 GO:0043565 sequence-specific DNA binding
2.84 1.53e-05 GO:0004714 transmembrane receptor protein tyrosine kinase activity
1.66 2.08e-05 GO:0015267 channel activity
1.65 2.41e-05 GO:0022803 passive transmembrane transporter activity
1.48 2.77e-05 GO:0015075 ion transmembrane transporter activity
1.78 8.78e-05 GO:0005261 cation channel activity
1.46 9.64e-05 GO:0042802 identical protein binding
1.38 1.54e-04 GO:0022892 substrate-specific transporter activity
1.41 1.78e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.39 2.64e-04 GO:0022857 transmembrane transporter activity
1.48 4.90e-04 GO:0004672 protein kinase activity
4.47 5.13e-04 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.48 1.26e-03 GO:0008324 cation transmembrane transporter activity
1.32 1.33e-03 GO:0005215 transporter activity
3.41 1.70e-03 GO:0005158 insulin receptor binding
2.31 2.57e-03 GO:0005201 extracellular matrix structural constituent
1.97 2.85e-03 GO:0004713 protein tyrosine kinase activity
1.57 2.89e-03 GO:0030246 carbohydrate binding
3.48 5.59e-03 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
1.39 5.67e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.25 5.77e-03 GO:0004872 receptor activity
1.74 8.51e-03 GO:0000975 regulatory region DNA binding
1.74 8.51e-03 GO:0001067 regulatory region nucleic acid binding
1.74 8.51e-03 GO:0044212 transcription regulatory region DNA binding
1.37 8.85e-03 GO:0016301 kinase activity
1.32 9.83e-03 GO:0001071 nucleic acid binding transcription factor activity
1.32 9.83e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.75 9.90e-03 GO:0010843 promoter binding
3.34 1.07e-02 GO:0004112 cyclic-nucleotide phosphodiesterase activity
1.87 1.19e-02 GO:0005539 glycosaminoglycan binding
2.33 2.02e-02 GO:0005178 integrin binding
1.80 2.25e-02 GO:0001871 pattern binding
1.80 2.25e-02 GO:0030247 polysaccharide binding
2.03 2.41e-02 GO:0005057 receptor signaling protein activity
5.22 2.82e-02 GO:0043121 neurotrophin binding
1.39 3.74e-02 GO:0005198 structural molecule activity
1.90 4.08e-02 GO:0030674 protein binding, bridging
1.30 4.18e-02 GO:0030234 enzyme regulator activity
1.93 4.47e-02 GO:0008201 heparin binding
1.45 4.48e-02 GO:0042803 protein homodimerization activity
1.48 4.59e-02 GO:0008047 enzyme activator activity
1.76 4.92e-02 GO:0008083 growth factor activity