Motif ID: MZF1.p2

Z-value: 2.317


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_59084928-0.101.4e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_17217781 61.780 BASP1
brain abundant, membrane attached signal protein 1
chr5_+_17217474 52.930 NM_006317
 BASP1
brain abundant, membrane attached signal protein 1
chr12_-_6798419 51.606 ZNF384
zinc finger protein 384
chr19_-_36523540 50.444 NM_001199570
 CLIP3
CAP-GLY domain containing linker protein 3
chr12_-_6798528 50.091 NM_133476
 ZNF384
zinc finger protein 384
chr12_-_6798619 46.012 NM_001039920
NM_001135734
 ZNF384

zinc finger protein 384

chr9_+_130374466 43.609 NM_001032221
NM_003165
 STXBP1

syntaxin binding protein 1

chr6_-_29600668 42.697 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr2_+_17721806 38.803 NM_003385
 VSNL1
visinin-like 1
chr5_-_73936299 38.028 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr6_-_29600859 37.229 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_29600959 35.715 NM_001470
NM_021904
 GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chrX_+_103031797 34.151 PLP1
proteolipid protein 1
chr11_-_73309090 33.481 NM_015159
 FAM168A
family with sequence similarity 168, member A
chr19_-_36523770 30.651 NM_015526
 CLIP3
CAP-GLY domain containing linker protein 3
chr1_-_204380903 29.923 NM_032833
 PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr1_-_57045129 29.891 PPAP2B
phosphatidic acid phosphatase type 2B
chr11_-_64410785 29.609 NM_138734
 NRXN2
neurexin 2
chr2_+_17721983 29.017 VSNL1
visinin-like 1
chr14_-_23834417 28.639 EFS
embryonal Fyn-associated substrate

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 373 entries
enrichment   p-value GO term description
2.44 2.13e-02 GO:0060443 mammary gland morphogenesis
2.35 3.69e-06 GO:0007269 neurotransmitter secretion
2.23 2.11e-04 GO:0051494 negative regulation of cytoskeleton organization
2.13 3.60e-06 GO:0001505 regulation of neurotransmitter levels
2.08 3.68e-08 GO:0010639 negative regulation of organelle organization
2.05 3.10e-06 GO:0006836 neurotransmitter transport
1.90 3.22e-02 GO:0022612 gland morphogenesis
1.86 1.20e-03 GO:0030308 negative regulation of cell growth
1.85 4.66e-02 GO:0030178 negative regulation of Wnt receptor signaling pathway
1.84 8.95e-04 GO:0045792 negative regulation of cell size
1.83 2.90e-09 GO:0051129 negative regulation of cellular component organization
1.82 2.65e-03 GO:0031098 stress-activated protein kinase signaling cascade
1.79 1.76e-03 GO:0010959 regulation of metal ion transport
1.77 1.29e-02 GO:0003001 generation of a signal involved in cell-cell signaling
1.77 1.29e-02 GO:0023061 signal release
1.77 2.05e-02 GO:0001822 kidney development
1.77 2.58e-02 GO:0032956 regulation of actin cytoskeleton organization
1.76 1.96e-11 GO:0032535 regulation of cellular component size
1.75 2.26e-08 GO:0008361 regulation of cell size
1.75 1.83e-02 GO:0000187 activation of MAPK activity

Gene overrepresentation in compartment category:

Showing 1 to 20 of 79 entries
enrichment   p-value GO term description
2.36 1.86e-02 GO:0034704 calcium channel complex
2.11 2.58e-02 GO:0008287 protein serine/threonine phosphatase complex
2.09 5.15e-03 GO:0030658 transport vesicle membrane
2.05 8.78e-03 GO:0005905 coated pit
1.90 2.95e-03 GO:0033267 axon part
1.82 9.76e-04 GO:0005925 focal adhesion
1.80 1.43e-03 GO:0030133 transport vesicle
1.77 2.36e-03 GO:0005924 cell-substrate adherens junction
1.74 3.76e-03 GO:0030055 cell-substrate junction
1.72 9.10e-06 GO:0030424 axon
1.70 3.09e-04 GO:0005912 adherens junction
1.68 1.18e-04 GO:0070161 anchoring junction
1.68 3.98e-02 GO:0019717 synaptosome
1.63 1.08e-10 GO:0043005 neuron projection
1.63 4.48e-04 GO:0044297 cell body
1.63 5.26e-04 GO:0043025 neuronal cell body
1.60 1.44e-07 GO:0044433 cytoplasmic vesicle part
1.59 4.53e-03 GO:0030136 clathrin-coated vesicle
1.58 8.22e-06 GO:0012506 vesicle membrane
1.58 8.38e-04 GO:0030135 coated vesicle

Gene overrepresentation in function category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
1.77 7.07e-03 GO:0005057 receptor signaling protein activity
1.75 8.76e-07 GO:0010843 promoter binding
1.72 2.12e-06 GO:0000975 regulatory region DNA binding
1.72 2.12e-06 GO:0001067 regulatory region nucleic acid binding
1.72 2.12e-06 GO:0044212 transcription regulatory region DNA binding
1.71 3.14e-02 GO:0051427 hormone receptor binding
1.67 2.14e-03 GO:0003714 transcription corepressor activity
1.63 1.13e-11 GO:0019904 protein domain specific binding
1.60 1.35e-06 GO:0008134 transcription factor binding
1.60 4.63e-04 GO:0019901 protein kinase binding
1.59 4.26e-02 GO:0004713 protein tyrosine kinase activity
1.58 3.79e-04 GO:0003713 transcription coactivator activity
1.57 4.97e-15 GO:0043565 sequence-specific DNA binding
1.57 6.56e-08 GO:0000988 protein binding transcription factor activity
1.57 6.56e-08 GO:0000989 transcription factor binding transcription factor activity
1.57 1.05e-07 GO:0003712 transcription cofactor activity
1.55 9.90e-06 GO:0016563 transcription activator activity
1.54 1.05e-05 GO:0003779 actin binding
1.54 4.24e-04 GO:0003702 RNA polymerase II transcription factor activity
1.52 1.83e-03 GO:0019900 kinase binding