Motif ID: NANOG.p2

Z-value: 1.062


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_79419940.338.8e-07Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_16760935 14.527 NM_001001395
NM_001243609
 LMO3

LIM domain only 3 (rhombotin-like 2)

chr6_-_32497925 12.800 NM_002125
 HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr15_+_58430394 10.602 NM_020980
 AQP9
aquaporin 9
chr7_-_37025696 10.178 ELMO1
engulfment and cell motility 1
chr12_-_16759939 9.399 NM_001243613
 LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_103031753 9.390 NM_000533
NM_199478
 PLP1

proteolipid protein 1

chr12_-_16759733 8.318 NM_001243610
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_25268057 8.058 NM_022150
 NPVF
neuropeptide VF precursor
chrX_+_103031797 7.946 PLP1
proteolipid protein 1
chr18_+_21572736 7.630 NM_153211
 TTC39C
tetratricopeptide repeat domain 39C
chr16_+_6823809 7.354 NM_001142334
 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_176734181 6.997 NM_201591
 GPM6A
glycoprotein M6A
chr12_+_25205488 6.243 LRMP
lymphoid-restricted membrane protein
chr4_+_71587674 6.124 NM_001037442
NM_014961
 RUFY3

RUN and FYVE domain containing 3

chr4_+_113970784 6.090 NM_001148
NM_020977
 ANK2

ankyrin 2, neuronal

chr3_-_12941547 6.001 IQSEC1
IQ motif and Sec7 domain 1
chr3_+_115342302 5.998 GAP43
growth associated protein 43
chr13_-_95131718 5.837 NM_001129889
NM_001922
 DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)

chr10_+_11206928 5.803 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr6_-_32557431 5.792 NM_001243965
NM_002124
 HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
6.87 8.32e-03 GO:0051149 positive regulation of muscle cell differentiation
3.85 7.47e-03 GO:0001503 ossification
3.01 1.35e-02 GO:0007601 visual perception
3.01 1.35e-02 GO:0050953 sensory perception of light stimulus
2.99 3.42e-03 GO:0045596 negative regulation of cell differentiation
2.75 4.07e-03 GO:0051093 negative regulation of developmental process
2.57 2.11e-02 GO:0044057 regulation of system process
2.54 1.83e-06 GO:0045595 regulation of cell differentiation
2.52 3.45e-04 GO:0007417 central nervous system development
2.41 4.13e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.32 2.99e-05 GO:0007267 cell-cell signaling
2.32 2.57e-02 GO:0051094 positive regulation of developmental process
2.21 3.43e-04 GO:2000026 regulation of multicellular organismal development
2.20 2.15e-05 GO:0050793 regulation of developmental process
2.18 6.93e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.11 8.71e-03 GO:0010628 positive regulation of gene expression
2.05 1.51e-04 GO:0007154 cell communication
2.03 3.64e-02 GO:0051254 positive regulation of RNA metabolic process
2.02 1.21e-02 GO:0006955 immune response
2.00 1.93e-02 GO:0010557 positive regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
15.27 1.78e-02 GO:0033162 melanosome membrane
15.27 1.78e-02 GO:0045009 chitosome
10.91 1.44e-02 GO:0042613 MHC class II protein complex
1.74 1.21e-02 GO:0044421 extracellular region part
1.62 1.59e-04 GO:0005576 extracellular region
1.61 3.97e-02 GO:0005887 integral to plasma membrane
1.45 2.26e-02 GO:0044459 plasma membrane part
1.29 4.94e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.27 7.53e-03 GO:0008083 growth factor activity
2.23 9.62e-05 GO:0043565 sequence-specific DNA binding
2.17 9.19e-07 GO:0001071 nucleic acid binding transcription factor activity
2.17 9.19e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.76 1.31e-02 GO:0005102 receptor binding