Motif ID: NANOG.p2

Z-value: 1.062


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_79419940.338.8e-07Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_16760935 14.527 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr6_-_32497925 12.800 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr15_+_58430394 10.602 NM_020980
AQP9
aquaporin 9
chr7_-_37025696 10.178 ELMO1
engulfment and cell motility 1
chr12_-_16759939 9.399 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_103031753 9.390 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr12_-_16759733 8.318 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_25268057 8.058 NM_022150
NPVF
neuropeptide VF precursor
chrX_+_103031797 7.946 PLP1
proteolipid protein 1
chr18_+_21572736 7.630 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr16_+_6823809 7.354 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_176734181 6.997 NM_201591
GPM6A
glycoprotein M6A
chr12_+_25205488 6.243 LRMP
lymphoid-restricted membrane protein
chr4_+_71587674 6.124 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr4_+_113970784 6.090 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr3_-_12941547 6.001 IQSEC1
IQ motif and Sec7 domain 1
chr3_+_115342302 5.998 GAP43
growth associated protein 43
chr13_-_95131718 5.837 NM_001129889
NM_001922
DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)

chr10_+_11206928 5.803 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr6_-_32557431 5.792 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr2_+_226265601 5.743 NM_020864
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr1_+_198608136 5.634 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr4_-_174451356 5.631 NM_021973
HAND2
heart and neural crest derivatives expressed 2
chr1_+_198608216 5.559 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_+_25205180 5.518 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr7_-_14025826 5.474 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr3_+_115342150 5.474 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr6_-_31107110 5.407 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr5_-_88179278 5.386 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr2_+_162272892 5.333 TBR1
T-box, brain, 1
chr12_-_52779362 5.323 NM_033045
KRT84
keratin 84
chr12_-_52828105 5.275 NM_004693
KRT75
keratin 75
chr3_+_35722428 5.207 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_-_224467095 5.194 SCG2
secretogranin II
chr19_+_7968701 5.159 MAP2K7
mitogen-activated protein kinase kinase 7
chr10_-_13749622 5.154 FRMD4A
FERM domain containing 4A
chr12_-_15114495 5.125 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_-_186578122 5.095 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr10_-_52645384 5.031 A1CF
APOBEC1 complementation factor
chr5_-_112630301 4.951 MCC
mutated in colorectal cancers
chr1_+_209878135 4.907 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr11_-_57195052 4.893 NM_017611
SLC43A3
solute carrier family 43, member 3
chr1_-_150738232 4.855 CTSS
cathepsin S
chr14_+_101295409 4.763 MEG3
maternally expressed 3 (non-protein coding)
chr2_-_217724781 4.730 NM_003284
TNP1
transition protein 1 (during histone to protamine replacement)
chr16_+_6533758 4.538 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr6_+_50786438 4.477 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr12_-_6233684 4.449 NM_000552
VWF
von Willebrand factor
chr14_+_92789536 4.428 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr10_+_11207053 4.427 CELF2
CUGBP, Elav-like family member 2
chr15_+_89631731 4.400 ABHD2
abhydrolase domain containing 2
chr3_+_35721115 4.389 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr12_-_4488707 4.377 NM_020638
FGF23
fibroblast growth factor 23
chr3_+_111717585 4.360 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr16_-_21314371 4.328 NM_001014444
NM_001888
CRYM

crystallin, mu

chr15_+_89631695 4.298 ABHD2
abhydrolase domain containing 2
chr12_+_51318743 4.254 METTL7A
methyltransferase like 7A
chr2_-_224467049 4.239 SCG2
secretogranin II
chr19_+_45409003 4.198 NM_000041
APOE
apolipoprotein E
chr20_+_36932551 4.197 NM_001725
BPI
bactericidal/permeability-increasing protein
chr3_+_129247481 4.190 NM_000539
RHO
rhodopsin
chr1_+_50574601 4.174 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_+_50575465 4.172 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_10421858 4.118 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr3_+_152880036 4.055 RAP2B
RAP2B, member of RAS oncogene family
chr19_+_45971249 4.051 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr5_-_112630557 3.889 NM_002387
MCC
mutated in colorectal cancers
chr11_-_128712340 3.866 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr15_+_89631625 3.865 ABHD2
abhydrolase domain containing 2
chr3_+_69985750 3.864 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr10_+_35416384 3.849 NM_181571
NM_183060
CREM

cAMP responsive element modulator

chr2_+_210444154 3.843 MAP2
microtubule-associated protein 2
chr1_+_151739130 3.812 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr4_-_176733901 3.797 GPM6A
glycoprotein M6A
chr4_-_57547845 3.562 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr14_-_60097314 3.561 RTN1
reticulon 1
chr12_+_8276227 3.530 NM_016184
NM_194447
NM_194448
NM_194450
CLEC4A



C-type lectin domain family 4, member A



chrX_+_28605558 3.525 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr9_+_120466453 3.513 NM_138554
TLR4
toll-like receptor 4
chr14_+_35514112 3.464 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr4_-_80329354 3.463 NM_033214
GK2
glycerol kinase 2
chr13_+_102104941 3.437 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_+_6105980 3.402 NM_001199862
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr9_+_120466625 3.354 TLR4
toll-like receptor 4
chr14_+_92788924 3.309 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_+_32407618 3.309 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr3_+_121796695 3.287 NM_006889
NM_176892
CD86

CD86 molecule

chr8_-_40755328 3.250 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chr8_+_24298442 3.234 NM_003817
ADAM7
ADAM metallopeptidase domain 7
chr12_+_51318515 3.158 NM_014033
METTL7A
methyltransferase like 7A
chr2_-_224467142 3.156 NM_003469
SCG2
secretogranin II
chr2_+_162272619 3.145 NM_006593
TBR1
T-box, brain, 1
chr20_+_30697291 3.136 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr11_-_83393436 3.119 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr12_-_16757944 3.115 LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_121379757 3.096 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr11_-_102595623 3.076 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr20_+_2276612 3.051 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr5_-_149466173 3.047 CSF1R
colony stimulating factor 1 receptor
chr18_+_32173281 3.045 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chrX_-_137821514 3.039 NM_033642
FGF13
fibroblast growth factor 13
chr6_+_32605182 3.017 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr7_-_137028533 3.016 NM_002825
PTN
pleiotrophin
chr5_+_140809957 3.007 PCDHGA12
protocadherin gamma subfamily A, 12
chr2_+_162272800 2.998 TBR1
T-box, brain, 1
chr16_+_8814567 2.943 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr5_-_140013034 2.915 NM_000591
CD14
CD14 molecule
chr2_+_169757749 2.909 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr9_-_5339745 2.894 NM_006911
RLN1
relaxin 1
chr9_+_82187469 2.891 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr21_-_39956823 2.888 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr7_+_39017608 2.862 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr9_+_82187599 2.837 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_-_117748200 2.837 NM_001164831
FXYD6
FXYD domain containing ion transport regulator 6
chr6_-_26189303 2.834 NM_003539
HIST1H4D
histone cluster 1, H4d
chr3_-_121379701 2.795 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_156119734 2.792 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr21_-_31538970 2.763 NM_012131
CLDN17
claudin 17
chr19_-_45826232 2.727 NM_001824
CKM
creatine kinase, muscle
chr2_+_210444364 2.727 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr5_+_170736287 2.719 NM_021025
TLX3
T-cell leukemia homeobox 3
chr12_-_24103953 2.695 SOX5
SRY (sex determining region Y)-box 5
chr11_+_818836 2.693 NM_020376
PNPLA2
patatin-like phospholipase domain containing 2
chr2_-_166930130 2.667 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr10_+_49609641 2.661 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr12_-_102874299 2.658 IGF1
insulin-like growth factor 1 (somatomedin C)
chr7_-_115670774 2.657 TFEC
transcription factor EC
chr12_-_16759531 2.648 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_14029641 2.643 NM_001163147
NM_004956
ETV1

ets variant 1

chr15_-_55563091 2.633 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr5_-_149466126 2.575 CSF1R
colony stimulating factor 1 receptor
chr1_+_101003692 2.569 NM_022049
GPR88
G protein-coupled receptor 88
chr5_-_88199868 2.568 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr11_+_88911039 2.482 NM_000372
TYR
tyrosinase (oculocutaneous albinism IA)
chr7_+_23286386 2.429 GPNMB
glycoprotein (transmembrane) nmb
chr11_-_72145343 2.427 NM_030813
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chrX_+_103031433 2.425 NM_001128834
PLP1
proteolipid protein 1
chr2_-_209010876 2.404 NM_005210
CRYGB
crystallin, gamma B
chr8_-_27115935 2.397 STMN4
stathmin-like 4
chr12_-_110252600 2.375 NM_001177431
NM_001177428
NM_001177433
NM_147204
TRPV4



transient receptor potential cation channel, subfamily V, member 4



chr5_-_42811959 2.356 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr14_+_23305816 2.351 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr1_-_154842725 2.350 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr2_+_234959345 2.349 NM_006944
SPP2
secreted phosphoprotein 2, 24kDa
chr11_-_72145602 2.331 CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr6_-_42690308 2.326 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr8_-_87755880 2.325 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chrX_+_110366304 2.303 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr19_+_7968765 2.298 MAP2K7
mitogen-activated protein kinase kinase 7
chr4_-_26491888 2.295 NM_000730
CCKAR
cholecystokinin A receptor
chr3_-_69171536 2.293 NM_198271
LMOD3
leiomodin 3 (fetal)
chr11_+_7618416 2.292 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_+_129015483 2.267 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr12_-_109027654 2.262 NM_003006
SELPLG
selectin P ligand
chr4_-_87281374 2.262 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr6_+_131894343 2.260 NM_000045
NM_001244438
ARG1

arginase, liver

chr2_-_65593763 2.255 SPRED2
sprouty-related, EVH1 domain containing 2
chr12_-_16759430 2.245 LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_66788682 2.243 NM_001011645
AR
androgen receptor
chr8_-_27101240 2.237 STMN4
stathmin-like 4
chr17_-_10452939 2.237 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr12_+_81110689 2.224 NM_005593
MYF5
myogenic factor 5
chr3_-_101039403 2.209 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr15_+_67841341 2.207 NM_001206804
MAP2K5
mitogen-activated protein kinase kinase 5
chr7_-_115670828 2.206 NM_001018058
NM_012252
TFEC

transcription factor EC

chr3_-_57234279 2.203 NM_003865
HESX1
HESX homeobox 1
chr17_-_9929567 2.198 NM_001130831
GAS7
growth arrest-specific 7
chr3_+_89156804 2.196 EPHA3
EPH receptor A3
chr17_+_41052813 2.183 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr1_+_50574589 2.180 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr22_+_40573879 2.173 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr18_-_3874688 2.171 NM_001242762
NM_001242763
DLGAP1

discs, large (Drosophila) homolog-associated protein 1

chr17_-_79105747 2.169 NM_004920
AATK
apoptosis-associated tyrosine kinase
chr10_-_52645430 2.164 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr12_-_102874373 2.157 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr12_-_4554779 2.156 NM_020996
FGF6
fibroblast growth factor 6
chr3_-_39321479 2.149 NM_001337
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr8_-_67090690 2.123 NM_000756
CRH
corticotropin releasing hormone
chr5_+_176853673 2.110 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr8_+_32579350 2.110 NM_001159996
NRG1
neuregulin 1
chr19_+_54641475 2.107 CNOT3
CCR4-NOT transcription complex, subunit 3
chr6_-_32634287 2.081 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr1_+_50569581 2.073 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_31803514 2.072 NM_001198546
NM_001198548
NM_003787
NOL4


nucleolar protein 4


chr18_-_31803168 2.065 NOL4
nucleolar protein 4
chr19_+_7968764 2.063 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr16_+_10522724 2.061 NM_024997
ATF7IP2
activating transcription factor 7 interacting protein 2
chr7_+_18535817 2.049 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr13_-_41593491 2.046 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr10_+_18549583 2.035 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_+_12693385 2.035 NM_000550
TYRP1
tyrosinase-related protein 1
chr11_+_58390145 2.022 NM_000614
CNTF
ciliary neurotrophic factor
chr13_-_41593405 2.014 ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_+_4854383 1.994 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr12_-_91398744 1.983 EPYC
epiphycan
chr6_-_136847609 1.958 MAP7
microtubule-associated protein 7
chr4_-_8873453 1.954 NM_018942
HMX1
H6 family homeobox 1
chr3_+_69812961 1.950 NM_006722
MITF
microphthalmia-associated transcription factor
chr11_-_117747618 1.948 NM_001204268
NM_001243598
NM_001164832
NM_001164836
NM_001164837
NM_022003
FXYD6-FXYD2

FXYD6



FXYD6-FXYD2 readthrough

FXYD domain containing ion transport regulator 6



chr14_-_21270537 1.943 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.66 5.36e-18 GO:0032501 multicellular organismal process
1.79 2.24e-13 GO:0007275 multicellular organismal development
1.73 6.29e-13 GO:0032502 developmental process
1.82 3.37e-11 GO:0048731 system development
1.76 6.96e-11 GO:0048856 anatomical structure development
1.62 5.00e-09 GO:0023052 signaling
1.92 4.84e-07 GO:0003008 system process
1.86 6.38e-07 GO:0048513 organ development
1.37 1.52e-06 GO:0050896 response to stimulus
1.50 1.59e-06 GO:0051716 cellular response to stimulus
1.30 1.62e-06 GO:0065007 biological regulation
2.54 1.83e-06 GO:0045595 regulation of cell differentiation
1.56 5.23e-06 GO:0007165 signal transduction
1.31 7.25e-06 GO:0050789 regulation of biological process
2.20 2.15e-05 GO:0050793 regulation of developmental process
1.74 2.21e-05 GO:0030154 cell differentiation
1.89 2.64e-05 GO:0007399 nervous system development
2.32 2.99e-05 GO:0007267 cell-cell signaling
1.69 9.19e-05 GO:0048869 cellular developmental process
2.05 1.51e-04 GO:0007154 cell communication
1.29 2.39e-04 GO:0050794 regulation of cellular process
1.72 3.36e-04 GO:0007166 cell surface receptor linked signaling pathway
2.21 3.43e-04 GO:2000026 regulation of multicellular organismal development
2.52 3.45e-04 GO:0007417 central nervous system development
1.88 3.77e-04 GO:0051239 regulation of multicellular organismal process
1.51 2.92e-03 GO:0048518 positive regulation of biological process
2.99 3.42e-03 GO:0045596 negative regulation of cell differentiation
2.75 4.07e-03 GO:0051093 negative regulation of developmental process
2.41 4.13e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.18 6.93e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.85 7.47e-03 GO:0001503 ossification
1.53 7.85e-03 GO:0048519 negative regulation of biological process
6.87 8.32e-03 GO:0051149 positive regulation of muscle cell differentiation
2.11 8.71e-03 GO:0010628 positive regulation of gene expression
1.73 9.39e-03 GO:0050877 neurological system process
2.02 1.21e-02 GO:0006955 immune response
1.95 1.26e-02 GO:0009891 positive regulation of biosynthetic process
3.01 1.35e-02 GO:0007601 visual perception
3.01 1.35e-02 GO:0050953 sensory perception of light stimulus
1.94 1.72e-02 GO:0031328 positive regulation of cellular biosynthetic process
2.00 1.93e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.14 1.99e-02 GO:0009987 cellular process
2.57 2.11e-02 GO:0044057 regulation of system process
2.32 2.57e-02 GO:0051094 positive regulation of developmental process
1.90 2.58e-02 GO:0006351 transcription, DNA-dependent
1.84 2.59e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.52 3.29e-02 GO:0048523 negative regulation of cellular process
2.03 3.64e-02 GO:0051254 positive regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.62 1.59e-04 GO:0005576 extracellular region
1.74 1.21e-02 GO:0044421 extracellular region part
10.91 1.44e-02 GO:0042613 MHC class II protein complex
15.27 1.78e-02 GO:0033162 melanosome membrane
15.27 1.78e-02 GO:0045009 chitosome
1.45 2.26e-02 GO:0044459 plasma membrane part
1.61 3.97e-02 GO:0005887 integral to plasma membrane
1.29 4.94e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.17 9.19e-07 GO:0001071 nucleic acid binding transcription factor activity
2.17 9.19e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
2.23 9.62e-05 GO:0043565 sequence-specific DNA binding
3.27 7.53e-03 GO:0008083 growth factor activity
1.76 1.31e-02 GO:0005102 receptor binding