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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: NFE2L1.p2

Z-value: 1.506

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_216259197	16.260		FN1	fibronectin 1
chr5_+_138211084	15.684		CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa
chr7_+_75931829	15.587	NM_001540	HSPB1	heat shock 27kDa protein 1
chr3_-_45267068	14.863		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr21_-_27253197	14.669		APP	amyloid beta (A4) precursor protein
chr7_+_75931991	14.388		HSPB1	heat shock 27kDa protein 1
chr21_+_47545896	13.249		COL6A2	collagen, type VI, alpha 2
chrX_-_10535476	13.112	NM_001193278 NM_001193279 NM_001193280 NM_001193281	MID1	midline 1 (Opitz/BBB syndrome)
chr9_+_97521930	12.200	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr3_+_158991035	11.847	NM_001197107 NM_001197108 NM_014575	SCHIP1	schwannomin interacting protein 1
chr21_+_47545189	10.701		COL6A2	collagen, type VI, alpha 2
chr10_+_102123420	10.563
chr5_+_34684611	10.403	NM_001145521 NM_001145525	RAI14	retinoic acid induced 14
chr1_+_44064509	9.726		PTPRF	protein tyrosine phosphatase, receptor type, F
chr7_+_94292737	9.625		PEG10	paternally expressed 10
chr5_+_140868721	9.117	NM_018929 NM_032407	PCDHGC5	protocadherin gamma subfamily C, 5
chr4_-_139163222	8.967	NM_014331	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_51701970	8.891		RNF11	ring finger protein 11
chr2_-_106015423	8.798	NM_001039492 NM_001450 NM_201555	FHL2	four and a half LIM domains 2
chr12_+_54422193	8.664	NM_004503	HOXC6	homeobox C6
chr8_+_145066886	8.649		GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_-_10419786	8.369	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_51701995	8.364		RNF11	ring finger protein 11
chr1_-_154943001	8.349	NM_001130040 NM_183001	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr2_-_47134945	8.075		MCFD2	multiple coagulation factor deficiency 2
chr14_-_103988829	7.455		CKB	creatine kinase, brain
chr11_-_27743604	7.411	NM_170731	BDNF	brain-derived neurotrophic factor
chr7_+_94292816	7.395		PEG10	paternally expressed 10
chrX_+_114827818	7.386	NM_001136025 NM_001172335	PLS3	plastin 3
chr22_+_38597938	7.250	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr3_-_127541160	7.237	NM_007283	MGLL	monoglyceride lipase
chr10_-_98325100	7.208		TM9SF3	transmembrane 9 superfamily member 3
chr2_-_55199894	7.123
chr4_+_41700736	6.998		LIMCH1	LIM and calponin homology domains 1
chr22_+_38598065	6.914		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr22_-_50720334	6.911		PLXNB2	plexin B2
chr17_-_48264039	6.860		COL1A1	collagen, type I, alpha 1
chrX_-_10645726	6.831	NM_001098624	MID1	midline 1 (Opitz/BBB syndrome)
chr2_+_201473942	6.811		AOX1	aldehyde oxidase 1
chr5_+_140729723	6.716	NM_018922 NM_032095	PCDHGB1	protocadherin gamma subfamily B, 1
chr5_+_102201526	6.569	NM_000919 NM_001177306 NM_138766 NM_138821 NM_138822	PAM	peptidylglycine alpha-amidating monooxygenase
chr5_+_140810181	6.509		PCDHGA12	protocadherin gamma subfamily A, 12
chr5_+_36608430	6.453	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_30712294	6.373	NM_003897	IER3	immediate early response 3
chrX_-_99891690	6.349	NM_003270	TSPAN6	tetraspanin 6
chr12_+_78225068	6.322	NM_014903	NAV3	neuron navigator 3
chr1_-_95392449	6.309		CNN3	calponin 3, acidic
chr10_+_75673346	6.067		PLAU	plasminogen activator, urokinase
chr2_-_74601653	6.062	NM_001135041 NM_023019	DCTN1	dynactin 1
chr7_+_116660291	6.061		ST7	suppression of tumorigenicity 7
chr15_-_34394071	6.041		C15orf24	chromosome 15 open reading frame 24
chr5_+_71403040	6.036	NM_005909	MAP1B	microtubule-associated protein 1B
chr1_-_95392501	6.034	NM_001839	CNN3	calponin 3, acidic
chr17_-_40575117	5.871	NM_012232	PTRF	polymerase I and transcript release factor
chr9_-_14313899	5.807		NFIB	nuclear factor I/B
chr22_+_38071612	5.805	NM_002305	LGALS1	lectin, galactoside-binding, soluble, 1
chr2_-_65593866	5.746	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr2_-_165551178	5.655		COBLL1	COBL-like 1
chr1_-_68697997	5.636	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr12_+_13349601	5.575	NM_001423	EMP1	epithelial membrane protein 1
chr17_-_46682333	5.524	NM_018952	HOXB6	homeobox B6
chr5_+_140753480	5.398	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr16_+_2564000	5.336		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr3_+_69812620	5.306	NM_001184967	MITF	microphthalmia-associated transcription factor
chr17_+_57784961	5.286		VMP1	vacuole membrane protein 1
chr15_-_34394016	5.238	NM_020154	C15orf24	chromosome 15 open reading frame 24
chr17_+_57785011	5.211		VMP1	vacuole membrane protein 1
chr17_+_57785010	5.192		VMP1	vacuole membrane protein 1
chr17_+_57785025	5.189		VMP1	vacuole membrane protein 1
chr9_-_16727887	5.170		BNC2	basonuclin 2
chr12_+_13349720	5.168		EMP1	epithelial membrane protein 1
chr10_+_121410751	5.162	NM_004281	BAG3	BCL2-associated athanogene 3
chr8_+_104831415	5.111	NM_014677	RIMS2	regulating synaptic membrane exocytosis 2
chr10_+_124220990	5.034	NM_002775	HTRA1	HtrA serine peptidase 1
chr10_+_121410891	5.003		BAG3	BCL2-associated athanogene 3
chr5_+_140810126	4.988	NM_003735 NM_032094	PCDHGA12	protocadherin gamma subfamily A, 12
chr12_-_14849427	4.956	NM_004963	GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)
chr1_-_155210887	4.928		GBA	glucosidase, beta, acid
chr12_-_6961044	4.890		CDCA3	cell division cycle associated 3
chr5_+_102201713	4.885		PAM	peptidylglycine alpha-amidating monooxygenase
chr4_+_88896899	4.870		SPP1	secreted phosphoprotein 1
chr17_+_57785059	4.864		VMP1	vacuole membrane protein 1
chr4_+_88896801	4.854	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr16_+_2563675	4.840	NM_001198569 NM_001694	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr4_-_186577858	4.786		SORBS2	sorbin and SH3 domain containing 2
chr17_-_15168590	4.779	NM_000304	PMP22	peripheral myelin protein 22
chr7_+_5632453	4.762		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr2_+_46524448	4.744	NM_001430	EPAS1	endothelial PAS domain protein 1
chr10_+_121411071	4.730		BAG3	BCL2-associated athanogene 3
chr4_+_88896868	4.676		SPP1	secreted phosphoprotein 1
chr7_+_134464161	4.668	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr2_+_109237679	4.663	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr5_-_175843360	4.643		CLTB	clathrin, light chain B
chr2_+_108994366	4.614	NM_006588	SULT1C4	sulfotransferase family, cytosolic, 1C, member 4
chr17_+_38137185	4.587		PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr4_+_88896838	4.577		SPP1	secreted phosphoprotein 1
chr17_-_48474678	4.559		LRRC59	leucine rich repeat containing 59
chr7_+_134464417	4.549		CALD1	caldesmon 1
chrX_+_102611379	4.516	NM_001006612 NM_001006613 NM_001006614 NM_016303	WBP5	WW domain binding protein 5
chr6_-_3157696	4.515	NM_001069	TUBB2A	tubulin, beta 2A class IIa
chr4_-_186578122	4.503	NM_001145674 NM_001145675	SORBS2	sorbin and SH3 domain containing 2
chr1_+_110560111	4.413		AHCYL1	adenosylhomocysteinase-like 1
chrX_+_70443055	4.379	NM_000166	GJB1	gap junction protein, beta 1, 32kDa
chr2_+_36583369	4.377	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_-_31832784	4.327		PAX6	paired box 6
chr11_-_31832758	4.326		PAX6	paired box 6
chr12_+_12938540	4.313	NM_030817	APOLD1	apolipoprotein L domain containing 1
chr17_-_42992852	4.227	NM_001131019 NM_001242376 NM_002055	GFAP	glial fibrillary acidic protein
chrX_-_13835187	4.221		GPM6B	glycoprotein M6B
chr6_+_7541863	4.169	NM_001008844 NM_004415	DSP	desmoplakin
chr4_-_80994183	4.142
chr10_+_121411042	4.104		BAG3	BCL2-associated athanogene 3
chr7_-_129592711	4.094	NM_001202498	UBE2H	ubiquitin-conjugating enzyme E2H
chr12_+_6647339	4.089		GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr11_-_6502563	4.087	NM_001242854 NM_001242855 NM_001242856 NM_012402	ARFIP2	ADP-ribosylation factor interacting protein 2
chr12_+_12764844	4.081		CREBL2	cAMP responsive element binding protein-like 2
chr6_-_46047978	4.057	NM_001114086	CLIC5	chloride intracellular channel 5
chr8_-_42065037	4.055		PLAT	plasminogen activator, tissue
chr8_+_132991171	4.049		EFR3A	EFR3 homolog A (S. cerevisiae)
chr5_+_125800786	4.042	NM_001146322	GRAMD3	GRAM domain containing 3
chr17_-_39684585	4.037	NM_002276	KRT19	keratin 19
chr11_-_14386051	4.037	NM_001177314	RRAS2	related RAS viral (r-ras) oncogene homolog 2
chr11_-_6502524	4.031		ARFIP2	ADP-ribosylation factor interacting protein 2
chr17_-_39684499	4.026		KRT19	keratin 19
chr5_+_179132676	4.007		CANX	calnexin
chr17_-_47785527	4.000		SLC35B1	solute carrier family 35, member B1
chr15_+_74218962	3.953		LOXL1	lysyl oxidase-like 1
chr6_+_7541837	3.941		DSP	desmoplakin
chr3_-_149095517	3.940	NM_014220	TM4SF1	transmembrane 4 L six family member 1
chr2_-_33824294	3.940	NM_015475	FAM98A	family with sequence similarity 98, member A
chr11_-_31832592	3.935		PAX6	paired box 6
chr20_+_44520021	3.899		CTSA	cathepsin A
chr7_+_116660263	3.892		ST7	suppression of tumorigenicity 7
chrM_+_4770	3.891
chr8_-_42065193	3.891	NM_000930 NM_033011	PLAT	plasminogen activator, tissue
chr20_+_44519924	3.882		CTSA	cathepsin A
chr20_+_44519590	3.881	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr13_+_111154013	3.867		COL4A2	collagen, type IV, alpha 2
chr5_+_140810326	3.862		PCDHGA12	protocadherin gamma subfamily A, 12
chr20_+_44519965	3.850		CTSA	cathepsin A
chr15_+_80364902	3.846	NM_001242915 NM_001242916	ZFAND6	zinc finger, AN1-type domain 6
chr16_+_2563977	3.838		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr15_+_96869156	3.831	NM_001145155	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr14_+_67831484	3.826		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr7_+_5632435	3.823	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr5_-_179229874	3.819	NM_054013	MGAT4B	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr10_+_128593994	3.773	NM_001380	DOCK1	dedicator of cytokinesis 1
chr8_+_38854431	3.771	NM_003816	ADAM9	ADAM metallopeptidase domain 9
chr13_-_45048436	3.765	NM_001243798	TSC22D1	TSC22 domain family, member 1
chr14_+_101295409	3.763		MEG3	maternally expressed 3 (non-protein coding)
chr16_+_2563993	3.737		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr22_-_50720961	3.736		PLXNB2	plexin B2
chr10_-_79686279	3.731	NM_004747	DLG5	discs, large homolog 5 (Drosophila)
chr6_+_7541892	3.725		DSP	desmoplakin
chr5_+_161277702	3.720	NM_001127648	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_+_5488521	3.709	NM_005863	NET1	neuroepithelial cell transforming 1
chr5_+_125758818	3.685	NM_001146320 NM_001146321 NM_023927	GRAMD3	GRAM domain containing 3
chr3_+_183894736	3.685		AP2M1	adaptor-related protein complex 2, mu 1 subunit
chrX_-_13835012	3.683		GPM6B	glycoprotein M6B
chr17_+_70117177	3.675		SOX9	SRY (sex determining region Y)-box 9
chr18_+_2571509	3.674	NM_006101	NDC80	NDC80 kinetochore complex component homolog (S. cerevisiae)
chrX_-_10588458	3.627	NM_000381 NM_033289	MID1	midline 1 (Opitz/BBB syndrome)
chr5_+_140864626	3.608	NM_018928 NM_032406	PCDHGC4	protocadherin gamma subfamily C, 4
chr1_-_59042827	3.607		TACSTD2	tumor-associated calcium signal transducer 2
chrX_+_153657119	3.603		ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1
chr2_-_47168870	3.582		MCFD2	multiple coagulation factor deficiency 2
chr16_+_2563914	3.578		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr12_+_53491417	3.564	NM_002178	IGFBP6	insulin-like growth factor binding protein 6
chr1_-_23885916	3.555		ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr6_-_112575880	3.541		LAMA4	laminin, alpha 4
chr1_+_65613971	3.540		AK4	adenylate kinase 4
chr15_-_72522062	3.533	NM_001206799	PKM2	pyruvate kinase, muscle
chr11_-_67450536	3.530		RPL37	ribosomal protein L37
chr7_+_872137	3.509	NM_001130965	SUN1	Sad1 and UNC84 domain containing 1
chr16_-_47005339	3.507		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr16_+_82660390	3.504	NM_001220488 NM_001220489 NM_001220490 NM_001220491 NM_001220492 NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr7_+_107221203	3.499	NM_001008405	BCAP29	B-cell receptor-associated protein 29
chr3_-_149095413	3.492		TM4SF1	transmembrane 4 L six family member 1
chr14_+_29236882	3.491		FOXG1	forkhead box G1
chr12_-_90049818	3.490	NM_001001323 NM_001682	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr1_+_51701943	3.480	NM_014372	RNF11	ring finger protein 11
chrX_+_47078053	3.477	NM_006201	CDK16	cyclin-dependent kinase 16
chr17_-_76989770	3.477		CANT1	calcium activated nucleotidase 1
chr15_+_74218786	3.472	NM_005576	LOXL1	lysyl oxidase-like 1
chr1_-_217250230	3.460	NM_001243507 NM_001243509	ESRRG	estrogen-related receptor gamma
chr17_+_38137088	3.457		PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr11_-_8832189	3.452	NM_213618	ST5	suppression of tumorigenicity 5
chr12_-_53343607	3.444		KRT8	keratin 8
chr18_+_2571587	3.434		NDC80	NDC80 kinetochore complex component homolog (S. cerevisiae)
chr9_-_14313509	3.433		NFIB	nuclear factor I/B
chr20_+_9458460	3.416		PLCB4	phospholipase C, beta 4
chr11_-_31832855	3.413	NM_000280 NM_001604	PAX6	paired box 6
chr6_-_110501164	3.408	NM_001024934 NM_001024935 NM_001024936 NM_003931	WASF1	WAS protein family, member 1
chr15_+_74218794	3.400		LOXL1	lysyl oxidase-like 1
chr17_+_70117168	3.397		SOX9	SRY (sex determining region Y)-box 9
chr16_-_87903028	3.395	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr11_-_33744497	3.394	NM_001127227	CD59	CD59 molecule, complement regulatory protein
chr5_+_137514753	3.384		KIF20A	kinesin family member 20A
chr19_+_3094528	3.383		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr7_-_6523689	3.375	NM_001100603 NM_006854	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.21	6.84e-40	GO:0009987	cellular process
1.46	7.45e-18	GO:0048731	system development
1.22	1.22e-17	GO:0065007	biological regulation
1.42	9.40e-17	GO:0048856	anatomical structure development
1.35	5.37e-14	GO:0032502	developmental process
1.49	1.04e-13	GO:0065008	regulation of biological quality
1.47	1.27e-13	GO:0042221	response to chemical stimulus
1.36	1.53e-13	GO:0007275	multicellular organismal development
1.42	3.59e-13	GO:0048518	positive regulation of biological process
1.44	5.43e-13	GO:0048522	positive regulation of cellular process
1.44	1.32e-12	GO:0048519	negative regulation of biological process
1.22	5.00e-12	GO:0044237	cellular metabolic process
1.56	1.20e-11	GO:0007399	nervous system development
1.19	1.49e-11	GO:0050789	regulation of biological process
1.45	1.52e-11	GO:0048523	negative regulation of cellular process
1.20	1.94e-11	GO:0008152	metabolic process
1.33	3.45e-11	GO:0071840	cellular component organization or biogenesis
1.20	4.17e-11	GO:0050794	regulation of cellular process
1.22	4.99e-11	GO:0050896	response to stimulus
1.33	5.80e-11	GO:0016043	cellular component organization
1.54	1.35e-10	GO:0009653	anatomical structure morphogenesis
1.27	2.04e-09	GO:0051716	cellular response to stimulus
1.29	2.42e-09	GO:0023052	signaling
1.23	5.67e-09	GO:0032501	multicellular organismal process
1.37	8.41e-09	GO:0006950	response to stress
2.18	1.45e-08	GO:0016337	cell-cell adhesion
1.34	1.55e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.71	1.74e-08	GO:0007155	cell adhesion
1.71	1.74e-08	GO:0022610	biological adhesion
1.29	4.18e-08	GO:0051179	localization
2.75	5.37e-08	GO:0007156	homophilic cell adhesion
1.34	5.41e-08	GO:0071842	cellular component organization at cellular level
1.31	9.73e-08	GO:0051234	establishment of localization
1.56	1.04e-07	GO:0051246	regulation of protein metabolic process
1.61	1.07e-07	GO:0048468	cell development
1.39	1.16e-07	GO:0030154	cell differentiation
1.18	1.46e-07	GO:0044238	primary metabolic process
1.51	1.47e-07	GO:0009893	positive regulation of metabolic process
1.31	2.15e-07	GO:0006810	transport
1.53	2.29e-07	GO:0010604	positive regulation of macromolecule metabolic process
1.57	2.30e-07	GO:0032268	regulation of cellular protein metabolic process
1.51	3.78e-07	GO:0031325	positive regulation of cellular metabolic process
1.37	6.35e-07	GO:0048869	cellular developmental process
1.27	9.10e-07	GO:0007165	signal transduction
1.83	1.27e-06	GO:0072358	cardiovascular system development
1.83	1.27e-06	GO:0072359	circulatory system development
1.27	2.18e-06	GO:0006807	nitrogen compound metabolic process
1.47	2.20e-06	GO:0010033	response to organic substance
1.44	3.21e-06	GO:0009966	regulation of signal transduction
1.40	4.94e-06	GO:0023051	regulation of signaling
1.60	6.03e-06	GO:0031399	regulation of protein modification process
1.55	6.24e-06	GO:0022008	neurogenesis
1.85	7.08e-06	GO:0051247	positive regulation of protein metabolic process
1.27	8.13e-06	GO:0034641	cellular nitrogen compound metabolic process
1.67	1.17e-05	GO:0051726	regulation of cell cycle
1.86	1.41e-05	GO:0032270	positive regulation of cellular protein metabolic process
1.54	1.76e-05	GO:0009611	response to wounding
1.55	1.80e-05	GO:0008219	cell death
1.74	2.39e-05	GO:0000904	cell morphogenesis involved in differentiation
1.59	2.61e-05	GO:0007267	cell-cell signaling
1.54	2.61e-05	GO:0016265	death
1.50	2.63e-05	GO:0007154	cell communication
1.48	3.08e-05	GO:0010646	regulation of cell communication
1.36	3.53e-05	GO:0044281	small molecule metabolic process
1.68	3.55e-05	GO:0048666	neuron development
1.29	3.66e-05	GO:0009058	biosynthetic process
2.64	3.91e-05	GO:0090068	positive regulation of cell cycle process
1.35	4.18e-05	GO:0048513	organ development
1.60	5.42e-05	GO:0030182	neuron differentiation
1.58	5.68e-05	GO:0071844	cellular component assembly at cellular level
1.65	5.87e-05	GO:0042060	wound healing
1.99	6.59e-05	GO:0007346	regulation of mitotic cell cycle
1.34	7.55e-05	GO:0048583	regulation of response to stimulus
1.91	8.23e-05	GO:0031401	positive regulation of protein modification process
1.27	9.64e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41	1.04e-04	GO:0033036	macromolecule localization
4.69	1.13e-04	GO:0016339	calcium-dependent cell-cell adhesion
1.52	1.15e-04	GO:0048699	generation of neurons
1.58	1.32e-04	GO:0009790	embryo development
1.44	1.44e-04	GO:0044248	cellular catabolic process
1.53	1.57e-04	GO:0051128	regulation of cellular component organization
1.61	1.65e-04	GO:0032989	cellular component morphogenesis
1.64	1.78e-04	GO:0050878	regulation of body fluid levels
1.69	2.06e-04	GO:0031175	neuron projection development
1.73	2.69e-04	GO:0048667	cell morphogenesis involved in neuron differentiation
1.90	3.18e-04	GO:0001944	vasculature development
1.38	3.68e-04	GO:0009056	catabolic process
1.83	3.77e-04	GO:0007411	axon guidance
1.46	3.90e-04	GO:0009892	negative regulation of metabolic process
1.50	3.98e-04	GO:0040011	locomotion
1.65	4.15e-04	GO:0044265	cellular macromolecule catabolic process
1.93	4.55e-04	GO:0001568	blood vessel development
1.45	4.68e-04	GO:0042981	regulation of apoptosis
1.76	5.06e-04	GO:0006163	purine nucleotide metabolic process
1.28	5.52e-04	GO:0044249	cellular biosynthetic process
1.54	5.56e-04	GO:0012501	programmed cell death
1.45	5.79e-04	GO:0009605	response to external stimulus
1.48	6.14e-04	GO:0031324	negative regulation of cellular metabolic process
1.70	6.29e-04	GO:0048812	neuron projection morphogenesis
1.44	6.57e-04	GO:0022607	cellular component assembly
1.41	6.70e-04	GO:0044085	cellular component biogenesis
1.57	8.15e-04	GO:0001932	regulation of protein phosphorylation
1.43	8.58e-04	GO:0043067	regulation of programmed cell death
1.55	9.03e-04	GO:0042325	regulation of phosphorylation
1.70	9.11e-04	GO:0072521	purine-containing compound metabolic process
1.64	9.17e-04	GO:0006935	chemotaxis
1.64	9.17e-04	GO:0042330	taxis
1.54	9.82e-04	GO:0043085	positive regulation of catalytic activity
1.43	1.03e-03	GO:0010941	regulation of cell death
1.64	1.10e-03	GO:0044283	small molecule biosynthetic process
1.53	1.17e-03	GO:0006915	apoptosis
1.49	1.21e-03	GO:0044093	positive regulation of molecular function
1.84	1.21e-03	GO:0009144	purine nucleoside triphosphate metabolic process
1.82	1.51e-03	GO:0009141	nucleoside triphosphate metabolic process
1.53	1.56e-03	GO:0019220	regulation of phosphate metabolic process
1.53	1.56e-03	GO:0051174	regulation of phosphorus metabolic process
1.76	1.57e-03	GO:0010564	regulation of cell cycle process
1.99	1.58e-03	GO:0048514	blood vessel morphogenesis
1.83	1.72e-03	GO:0009205	purine ribonucleoside triphosphate metabolic process
2.79	1.82e-03	GO:0051352	negative regulation of ligase activity
2.79	1.82e-03	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.78	1.96e-03	GO:0009259	ribonucleotide metabolic process
1.79	1.99e-03	GO:0009150	purine ribonucleotide metabolic process
1.83	1.99e-03	GO:0009199	ribonucleoside triphosphate metabolic process
1.53	2.29e-03	GO:0009719	response to endogenous stimulus
2.80	2.72e-03	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.68	3.00e-03	GO:0007409	axonogenesis
1.62	3.09e-03	GO:0048585	negative regulation of response to stimulus
1.34	3.11e-03	GO:0065009	regulation of molecular function
1.44	3.33e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.95	3.78e-03	GO:0000075	cell cycle checkpoint
1.55	4.09e-03	GO:0009725	response to hormone stimulus
2.95	4.52e-03	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
2.16	5.08e-03	GO:0000082	G1/S transition of mitotic cell cycle
1.36	5.71e-03	GO:0051641	cellular localization
1.54	5.96e-03	GO:0000902	cell morphogenesis
1.66	6.13e-03	GO:0009968	negative regulation of signal transduction
2.33	6.26e-03	GO:0000077	DNA damage checkpoint
1.82	6.45e-03	GO:0015980	energy derivation by oxidation of organic compounds
1.67	7.29e-03	GO:0006091	generation of precursor metabolites and energy
1.53	7.74e-03	GO:0009057	macromolecule catabolic process
1.84	7.88e-03	GO:0008361	regulation of cell size
2.31	7.90e-03	GO:0042770	signal transduction in response to DNA damage
1.42	8.34e-03	GO:0070887	cellular response to chemical stimulus
1.37	9.46e-03	GO:0050790	regulation of catalytic activity
1.55	9.55e-03	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.38	9.67e-03	GO:0051649	establishment of localization in cell
1.51	9.81e-03	GO:0007167	enzyme linked receptor protein signaling pathway
2.29	9.93e-03	GO:0031398	positive regulation of protein ubiquitination
1.59	1.02e-02	GO:0007596	blood coagulation
1.59	1.02e-02	GO:0050817	coagulation
1.58	1.03e-02	GO:0006753	nucleoside phosphate metabolic process
1.58	1.03e-02	GO:0009117	nucleotide metabolic process
2.26	1.04e-02	GO:0031570	DNA integrity checkpoint
1.42	1.27e-02	GO:0042592	homeostatic process
1.88	1.32e-02	GO:0071156	regulation of cell cycle arrest
1.44	1.36e-02	GO:0033554	cellular response to stress
1.58	1.37e-02	GO:0007599	hemostasis
1.55	1.39e-02	GO:0019725	cellular homeostasis
2.65	1.42e-02	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
2.44	1.43e-02	GO:0030330	DNA damage response, signal transduction by p53 class mediator
3.52	1.70e-02	GO:0007416	synapse assembly
1.38	1.73e-02	GO:0008104	protein localization
1.44	1.82e-02	GO:0046907	intracellular transport
2.41	1.84e-02	GO:0031397	negative regulation of protein ubiquitination
1.49	1.91e-02	GO:0046483	heterocycle metabolic process
2.07	1.98e-02	GO:0034330	cell junction organization
1.66	1.98e-02	GO:0009792	embryo development ending in birth or egg hatching
1.77	2.04e-02	GO:0061061	muscle structure development
1.50	2.06e-02	GO:0048878	chemical homeostasis
1.34	2.11e-02	GO:0051239	regulation of multicellular organismal process
1.60	2.11e-02	GO:0023057	negative regulation of signaling
1.64	2.11e-02	GO:0006886	intracellular protein transport
3.07	2.13e-02	GO:0042773	ATP synthesis coupled electron transport
3.07	2.13e-02	GO:0042775	mitochondrial ATP synthesis coupled electron transport
2.53	2.22e-02	GO:0045787	positive regulation of cell cycle
1.60	2.33e-02	GO:0010648	negative regulation of cell communication
2.70	2.39e-02	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.70	2.39e-02	GO:0072395	signal transduction involved in cell cycle checkpoint
2.70	2.39e-02	GO:0072401	signal transduction involved in DNA integrity checkpoint
2.70	2.39e-02	GO:0072404	signal transduction involved in G1/S transition checkpoint
2.70	2.39e-02	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
2.70	2.39e-02	GO:0072422	signal transduction involved in DNA damage checkpoint
2.70	2.39e-02	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.70	2.39e-02	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
2.15	2.45e-02	GO:0045333	cellular respiration
1.70	2.69e-02	GO:0006511	ubiquitin-dependent protein catabolic process
1.81	2.76e-02	GO:0032269	negative regulation of cellular protein metabolic process
1.69	2.78e-02	GO:0019941	modification-dependent protein catabolic process
1.58	2.88e-02	GO:0008283	cell proliferation
1.15	2.88e-02	GO:0043170	macromolecule metabolic process
1.56	2.95e-02	GO:0019226	transmission of nerve impulse
1.56	2.95e-02	GO:0035637	multicellular organismal signaling
1.55	2.95e-02	GO:0032990	cell part morphogenesis
1.48	3.07e-02	GO:0030030	cell projection organization
1.60	3.10e-02	GO:0006873	cellular ion homeostasis
2.00	3.22e-02	GO:0010498	proteasomal protein catabolic process
2.00	3.22e-02	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.54	3.35e-02	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.81	3.39e-02	GO:0001558	regulation of cell growth
2.03	3.42e-02	GO:0043062	extracellular structure organization
1.68	3.52e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.67	3.63e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
3.50	3.78e-02	GO:0060338	regulation of type I interferon-mediated signaling pathway
1.98	3.82e-02	GO:0031400	negative regulation of protein modification process
1.54	3.88e-02	GO:0034613	cellular protein localization
1.49	3.89e-02	GO:0009887	organ morphogenesis
1.57	4.24e-02	GO:0016044	cellular membrane organization
1.58	4.63e-02	GO:0007268	synaptic transmission
1.53	4.63e-02	GO:0044092	negative regulation of molecular function
1.92	4.65e-02	GO:0003012	muscle system process
2.44	4.91e-02	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.27	2.23e-33	GO:0005737	cytoplasm
1.31	3.20e-25	GO:0044444	cytoplasmic part
1.13	1.39e-15	GO:0044424	intracellular part
1.12	1.96e-13	GO:0005622	intracellular
1.21	4.29e-10	GO:0044422	organelle part
1.38	1.97e-09	GO:0044459	plasma membrane part
1.20	1.01e-08	GO:0044446	intracellular organelle part
1.63	1.23e-08	GO:0005626	insoluble fraction
1.53	2.67e-08	GO:0000267	cell fraction
1.67	4.01e-08	GO:0016023	cytoplasmic membrane-bounded vesicle
1.66	4.69e-08	GO:0031988	membrane-bounded vesicle
1.64	5.16e-08	GO:0031410	cytoplasmic vesicle
1.62	6.96e-08	GO:0005624	membrane fraction
1.12	7.89e-08	GO:0043229	intracellular organelle
1.12	8.14e-08	GO:0043226	organelle
1.29	1.10e-07	GO:0043234	protein complex
1.61	1.90e-07	GO:0031982	vesicle
1.69	4.74e-07	GO:0030054	cell junction
1.12	1.19e-06	GO:0043231	intracellular membrane-bounded organelle
1.12	1.26e-06	GO:0043227	membrane-bounded organelle
1.24	2.04e-06	GO:0032991	macromolecular complex
1.21	8.69e-06	GO:0071944	cell periphery
1.76	2.09e-05	GO:0045202	synapse
1.20	2.10e-05	GO:0005886	plasma membrane
1.76	2.25e-05	GO:0043005	neuron projection
1.31	2.31e-05	GO:0005829	cytosol
1.30	2.74e-05	GO:0031090	organelle membrane
2.70	3.38e-05	GO:0042470	melanosome
2.70	3.38e-05	GO:0048770	pigment granule
2.13	6.11e-05	GO:0030424	axon
1.38	6.22e-05	GO:0005739	mitochondrion
1.04	6.34e-05	GO:0044464	cell part
1.04	6.63e-05	GO:0005623	cell
2.98	1.05e-04	GO:0000502	proteasome complex
1.52	3.11e-04	GO:0044429	mitochondrial part
1.64	5.30e-04	GO:0031966	mitochondrial membrane
1.11	7.96e-04	GO:0016020	membrane
1.43	1.04e-03	GO:0042995	cell projection
2.26	1.06e-03	GO:0030016	myofibril
1.60	1.14e-03	GO:0005740	mitochondrial envelope
1.45	1.23e-03	GO:0005615	extracellular space
2.20	1.68e-03	GO:0043292	contractile fiber
2.00	2.24e-03	GO:0070161	anchoring junction
3.52	2.60e-03	GO:0005913	cell-cell adherens junction
1.36	4.85e-03	GO:0044421	extracellular region part
1.70	5.48e-03	GO:0015629	actin cytoskeleton
1.84	1.03e-02	GO:0005911	cell-cell junction
1.31	1.11e-02	GO:0005887	integral to plasma membrane
2.12	1.23e-02	GO:0044449	contractile fiber part
1.96	1.24e-02	GO:0005912	adherens junction
1.33	1.49e-02	GO:0005783	endoplasmic reticulum
1.20	1.62e-02	GO:0043228	non-membrane-bounded organelle
1.20	1.62e-02	GO:0043232	intracellular non-membrane-bounded organelle
1.62	1.70e-02	GO:0019866	organelle inner membrane
1.30	1.78e-02	GO:0031226	intrinsic to plasma membrane
1.64	2.16e-02	GO:0005743	mitochondrial inner membrane
1.21	2.54e-02	GO:0031974	membrane-enclosed lumen
1.26	3.10e-02	GO:0005856	cytoskeleton
2.14	3.30e-02	GO:0030017	sarcomere
1.80	3.37e-02	GO:0030425	dendrite
1.39	4.03e-02	GO:0031975	envelope
1.59	4.55e-02	GO:0044433	cytoplasmic vesicle part
1.61	4.81e-02	GO:0044456	synapse part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.29	4.63e-31	GO:0005515	protein binding
1.13	1.29e-18	GO:0005488	binding
1.90	1.48e-04	GO:0032403	protein complex binding
1.43	2.34e-04	GO:0005102	receptor binding
1.50	2.58e-04	GO:0042802	identical protein binding
1.53	4.51e-04	GO:0005509	calcium ion binding
1.56	1.58e-03	GO:0008092	cytoskeletal protein binding
1.44	5.68e-03	GO:0019899	enzyme binding
1.88	1.85e-02	GO:0005126	cytokine receptor binding
1.82	2.90e-02	GO:0005125	cytokine activity
1.89	4.51e-02	GO:0008083	growth factor activity