Motif ID: NFE2L1.p2

Z-value: 1.506


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L1chr17_+_461256750.511.6e-15Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_216259197 16.260 FN1
fibronectin 1
chr5_+_138211084 15.684 CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr7_+_75931829 15.587 NM_001540
 HSPB1
heat shock 27kDa protein 1
chr3_-_45267068 14.863 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr21_-_27253197 14.669 APP
amyloid beta (A4) precursor protein
chr7_+_75931991 14.388 HSPB1
heat shock 27kDa protein 1
chr21_+_47545896 13.249 COL6A2
collagen, type VI, alpha 2
chrX_-_10535476 13.112 NM_001193278
NM_001193279
NM_001193280
NM_001193281
 MID1



midline 1 (Opitz/BBB syndrome)



chr9_+_97521930 12.200 NM_001193329
 C9orf3
chromosome 9 open reading frame 3
chr3_+_158991035 11.847 NM_001197107
NM_001197108
NM_014575
 SCHIP1


schwannomin interacting protein 1


chr21_+_47545189 10.701 COL6A2
collagen, type VI, alpha 2
chr10_+_102123420 10.563


chr5_+_34684611 10.403 NM_001145521
NM_001145525
 RAI14

retinoic acid induced 14

chr1_+_44064509 9.726 PTPRF
protein tyrosine phosphatase, receptor type, F
chr7_+_94292737 9.625 PEG10
paternally expressed 10
chr5_+_140868721 9.117 NM_018929
NM_032407
 PCDHGC5

protocadherin gamma subfamily C, 5

chr4_-_139163222 8.967 NM_014331
 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_51701970 8.891 RNF11
ring finger protein 11
chr2_-_106015423 8.798 NM_001039492
NM_001450
NM_201555
 FHL2


four and a half LIM domains 2


chr12_+_54422193 8.664 NM_004503
 HOXC6
homeobox C6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 212 entries
enrichment   p-value GO term description
4.69 1.13e-04 GO:0016339 calcium-dependent cell-cell adhesion
3.52 1.70e-02 GO:0007416 synapse assembly
3.50 3.78e-02 GO:0060338 regulation of type I interferon-mediated signaling pathway
3.07 2.13e-02 GO:0042773 ATP synthesis coupled electron transport
3.07 2.13e-02 GO:0042775 mitochondrial ATP synthesis coupled electron transport
2.95 4.52e-03 GO:0042058 regulation of epidermal growth factor receptor signaling pathway
2.80 2.72e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.79 1.82e-03 GO:0051352 negative regulation of ligase activity
2.79 1.82e-03 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.75 5.37e-08 GO:0007156 homophilic cell adhesion
2.70 2.39e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.70 2.39e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.70 2.39e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.70 2.39e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.70 2.39e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.70 2.39e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.70 2.39e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.70 2.39e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.65 1.42e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.64 3.91e-05 GO:0090068 positive regulation of cell cycle process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 63 entries
enrichment   p-value GO term description
3.52 2.60e-03 GO:0005913 cell-cell adherens junction
2.98 1.05e-04 GO:0000502 proteasome complex
2.70 3.38e-05 GO:0042470 melanosome
2.70 3.38e-05 GO:0048770 pigment granule
2.26 1.06e-03 GO:0030016 myofibril
2.20 1.68e-03 GO:0043292 contractile fiber
2.14 3.30e-02 GO:0030017 sarcomere
2.13 6.11e-05 GO:0030424 axon
2.12 1.23e-02 GO:0044449 contractile fiber part
2.00 2.24e-03 GO:0070161 anchoring junction
1.96 1.24e-02 GO:0005912 adherens junction
1.84 1.03e-02 GO:0005911 cell-cell junction
1.80 3.37e-02 GO:0030425 dendrite
1.76 2.09e-05 GO:0045202 synapse
1.76 2.25e-05 GO:0043005 neuron projection
1.70 5.48e-03 GO:0015629 actin cytoskeleton
1.69 4.74e-07 GO:0030054 cell junction
1.67 4.01e-08 GO:0016023 cytoplasmic membrane-bounded vesicle
1.66 4.69e-08 GO:0031988 membrane-bounded vesicle
1.64 5.16e-08 GO:0031410 cytoplasmic vesicle

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.90 1.48e-04 GO:0032403 protein complex binding
1.89 4.51e-02 GO:0008083 growth factor activity
1.88 1.85e-02 GO:0005126 cytokine receptor binding
1.82 2.90e-02 GO:0005125 cytokine activity
1.56 1.58e-03 GO:0008092 cytoskeletal protein binding
1.53 4.51e-04 GO:0005509 calcium ion binding
1.50 2.58e-04 GO:0042802 identical protein binding
1.44 5.68e-03 GO:0019899 enzyme binding
1.43 2.34e-04 GO:0005102 receptor binding
1.29 4.63e-31 GO:0005515 protein binding
1.13 1.29e-18 GO:0005488 binding