Motif ID: NFIL3.p2

Z-value: 1.052


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIL3chr9_-_94186140-0.194.1e-03Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_133494275 41.080 TF
transferrin
chr10_-_95360959 39.688 NM_006744
RBP4
retinol binding protein 4, plasma
chr4_-_88450243 27.271 SPARCL1
SPARC-like 1 (hevin)
chr7_-_31380507 23.072 NM_022728
NEUROD6
neurogenic differentiation 6
chr5_-_140013285 21.947 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr9_+_139871954 20.460 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr9_+_139872014 20.173 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr5_-_140012730 19.924 CD14
CD14 molecule
chr4_+_74269971 19.901 NM_000477
ALB
albumin
chr5_+_36606456 19.145 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr5_+_36606667 17.983 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_-_45010937 17.320 TSC22D1
TSC22 domain family, member 1
chr5_+_172483285 16.997 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr19_-_46389307 16.713 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr8_-_110661007 16.331 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr20_+_17207680 16.167 PCSK2
proprotein convertase subtilisin/kexin type 2
chr16_-_30103204 16.084 NM_004608
TBX6
T-box 6
chr8_-_27941387 15.060 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr17_-_67240955 14.381 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr14_-_70263871 13.912 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
4.49 2.91e-05 GO:0008202 steroid metabolic process
3.51 2.92e-03 GO:0006954 inflammatory response
3.11 9.91e-03 GO:0051240 positive regulation of multicellular organismal process
2.33 3.82e-03 GO:0006952 defense response
2.00 4.99e-03 GO:0051239 regulation of multicellular organismal process
1.90 3.78e-02 GO:0010033 response to organic substance
1.86 4.47e-05 GO:0042221 response to chemical stimulus
1.75 1.32e-02 GO:0048583 regulation of response to stimulus
1.54 1.41e-03 GO:0023052 signaling
1.50 2.05e-02 GO:0007165 signal transduction
1.48 3.63e-03 GO:0051716 cellular response to stimulus
1.36 1.99e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
3.15 1.75e-02 GO:0005792 microsome
3.05 2.55e-02 GO:0042598 vesicular fraction
2.73 3.49e-02 GO:0005578 proteinaceous extracellular matrix
2.64 3.72e-06 GO:0005615 extracellular space
2.59 2.98e-02 GO:0031012 extracellular matrix
2.49 5.51e-07 GO:0044421 extracellular region part
2.24 9.63e-04 GO:0005626 insoluble fraction
2.12 7.34e-03 GO:0005624 membrane fraction
1.99 2.79e-03 GO:0000267 cell fraction
1.95 1.73e-03 GO:0005887 integral to plasma membrane
1.93 2.01e-06 GO:0005576 extracellular region
1.92 2.80e-03 GO:0031226 intrinsic to plasma membrane
1.62 7.67e-03 GO:0044459 plasma membrane part
1.36 3.71e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
49.09 5.68e-05 GO:0047023 androsterone dehydrogenase activity
36.82 1.11e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
29.46 2.74e-02 GO:0032052 bile acid binding
15.11 3.51e-02 GO:0004522 pancreatic ribonuclease activity
14.32 1.16e-04 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
13.64 7.84e-03 GO:0004033 aldo-keto reductase activity
12.28 3.72e-04 GO:0016229 steroid dehydrogenase activity
4.23 4.28e-02 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
2.59 1.54e-02 GO:0008289 lipid binding