Motif ID: NFIX.p2

Z-value: 1.560


Transcription factors associated with NFIX.p2:

Gene SymbolEntrez IDGene Name
NFIX 4784 nuclear factor I/X (CCAAT-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIXchr19_+_131347820.244.0e-04Click!


Activity profile for motif NFIX.p2.

activity profile for motif NFIX.p2


Sorted Z-values histogram for motif NFIX.p2

Sorted Z-values for motif NFIX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_150399980 38.927 NM_002084
 GPX3
glutathione peroxidase 3 (plasma)
chr5_+_150400132 38.038 GPX3
glutathione peroxidase 3 (plasma)
chr10_+_124220990 22.255 NM_002775
 HTRA1
HtrA serine peptidase 1
chr15_-_72668184 19.994 HEXA
hexosaminidase A (alpha polypeptide)
chr9_+_124030370 19.182 NM_001127662
NM_001127663
NM_001127664
NM_001127665
NM_001127666
NM_001127667
NM_198252
 GSN






gelsolin






chr9_+_124030455 18.890 GSN
gelsolin
chr11_-_72353435 18.288 NM_001143839
NM_001243784
 PDE2A

phosphodiesterase 2A, cGMP-stimulated

chr11_-_46722160 17.311 ARHGAP1
Rho GTPase activating protein 1
chr12_+_26348268 16.790 NM_001135823
 SSPN
sarcospan (Kras oncogene-associated gene)
chr18_-_74691951 16.206 MBP
myelin basic protein
chr11_-_46722139 16.099 ARHGAP1
Rho GTPase activating protein 1
chr9_+_124030413 16.059 GSN
gelsolin
chr17_+_37844325 16.012 NM_001005862
 ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr11_-_61735108 14.822 NM_002032
 FTH1
ferritin, heavy polypeptide 1
chr17_-_37844266 14.793 NM_033419
 PGAP3
post-GPI attachment to proteins 3
chr15_+_91769329 14.565 SV2B
synaptic vesicle glycoprotein 2B
chr10_+_88728187 14.263 NM_006829
 C10orf116
chromosome 10 open reading frame 116
chr20_-_44539542 13.805 PLTP
phospholipid transfer protein
chr1_-_36235422 13.693 NM_001190481
NM_022111
 CLSPN

claspin

chr11_-_46722115 13.682 NM_004308
 ARHGAP1
Rho GTPase activating protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
2.60 1.04e-02 GO:0006936 muscle contraction
2.48 1.82e-02 GO:0003012 muscle system process
1.90 6.31e-03 GO:0019226 transmission of nerve impulse
1.90 6.31e-03 GO:0035637 multicellular organismal signaling
1.76 8.38e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.66 3.51e-03 GO:0048468 cell development
1.55 7.84e-04 GO:0009966 regulation of signal transduction
1.53 4.29e-02 GO:0010646 regulation of cell communication
1.50 8.69e-04 GO:0023051 regulation of signaling
1.48 7.57e-03 GO:0009653 anatomical structure morphogenesis
1.47 6.95e-04 GO:0048583 regulation of response to stimulus
1.47 1.21e-02 GO:0007399 nervous system development
1.43 6.85e-03 GO:0007166 cell surface receptor linked signaling pathway
1.41 8.16e-04 GO:0042221 response to chemical stimulus
1.37 1.62e-06 GO:0023052 signaling
1.32 1.27e-03 GO:0007165 signal transduction
1.29 6.59e-04 GO:0051716 cellular response to stimulus
1.29 2.22e-02 GO:0048856 anatomical structure development
1.22 8.97e-03 GO:0032501 multicellular organismal process
1.21 2.73e-06 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.83 1.89e-02 GO:0043005 neuron projection
1.74 2.25e-02 GO:0000139 Golgi membrane
1.73 4.91e-03 GO:0044431 Golgi apparatus part
1.43 2.69e-02 GO:0005887 integral to plasma membrane
1.42 3.68e-02 GO:0031226 intrinsic to plasma membrane
1.38 2.16e-02 GO:0012505 endomembrane system
1.37 1.62e-03 GO:0044459 plasma membrane part
1.19 1.70e-03 GO:0044444 cytoplasmic part
1.15 3.89e-04 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.21 2.22e-02 GO:0005506 iron ion binding
1.50 2.81e-02 GO:0005102 receptor binding