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Motif ID: NFKB1_REL_RELA.p2

Z-value: 2.687

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_35873823	65.610	NM_020529	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr19_-_41859332	55.388		TGFB1	transforming growth factor, beta 1
chr19_-_41859830	53.119	NM_000660	TGFB1	transforming growth factor, beta 1
chr19_-_41859519	52.961		TGFB1	transforming growth factor, beta 1
chr5_-_149792276	48.621		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_-_31324975	43.030	NM_005514	HLA-B	major histocompatibility complex, class I, B
chr6_-_32551993	41.126		HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr6_-_31324955	39.796		HLA-B	major histocompatibility complex, class I, B
chr5_-_149792370	39.795	NM_001025158 NM_001025159 NM_004355	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr22_-_37640287	39.677	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_+_29974352	39.197		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr19_-_41859253	37.478		TGFB1	transforming growth factor, beta 1
chr22_+_22758538	37.303
chr6_+_29910246	32.299	NM_001242758 NM_002116	HLA-A	major histocompatibility complex, class I, A
chr6_-_31324898	32.233		HLA-B	major histocompatibility complex, class I, B
chr12_+_7055736	31.431	NM_080548	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr17_+_40440481	31.308		STAT5A	signal transducer and activator of transcription 5A
chr6_+_32605182	29.970	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr19_+_1067536	29.034		HMHA1	histocompatibility (minor) HA-1
chr16_+_85932766	28.957	NM_002163	IRF8	interferon regulatory factor 8
chr22_-_37640187	28.881		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_50776012	27.551	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr5_-_150466696	27.008	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr12_+_7055753	25.981		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr22_+_23213671	25.454		IGLV4-3	immunoglobulin lambda variable 4-3
chr6_-_31324564	24.792		HLA-B HLA-C	major histocompatibility complex, class I, B major histocompatibility complex, class I, C
chr4_+_103422730	24.325		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr11_-_3862183	23.670	NM_001665	RHOG	ras homolog gene family, member G (rho G)
chr16_+_50775960	23.604	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr19_+_42381189	23.126	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr4_+_103422479	23.018	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_103422822	22.675		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr15_+_85923739	22.306	NM_006738 NM_007200	AKAP13	A kinase (PRKA) anchor protein 13
chr19_+_2476122	21.998	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr14_+_24605366	21.574	NM_006263 NM_176783	PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr5_-_131826426	21.462	NM_002198	IRF1	interferon regulatory factor 1
chr1_-_27961623	21.430	NM_005248	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr13_-_46756326	21.120	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr4_+_103422553	20.886		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_+_7461591	20.580	NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13
chr11_+_102188180	20.332	NM_001165 NM_182962	BIRC3	baculoviral IAP repeat containing 3
chr5_-_150460599	19.016	NM_001252385 NM_001252386 NM_001252393 NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr6_-_32811773	18.831	NM_148919	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr22_-_37545944	18.650	NM_000878	IL2RB	interleukin 2 receptor, beta
chr22_+_22712091	18.629		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr2_+_68961912	18.613	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr6_+_29855506	18.546
chr5_-_150460550	17.992		TNIP1	TNFAIP3 interacting protein 1
chr14_-_96180402	17.780	NM_001098725 NM_021966	TCL1A	T-cell leukemia/lymphoma 1A
chr10_+_104155431	17.354	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr22_+_23222897	17.280		CYAT1	immunoglobulin lambda light chain-like
chr11_-_3862137	17.237		RHOG	ras homolog gene family, member G (rho G)
chr5_-_150467220	17.212	NM_001252390	TNIP1	TNFAIP3 interacting protein 1
chr16_+_3115611	17.103	NM_001012635	IL32	interleukin 32
chr2_+_69001932	17.065	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr22_+_23134980	17.007
chr10_+_104154228	16.987	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr6_+_138188352	16.974	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr5_-_171615239	16.839		STK10	serine/threonine kinase 10
chr17_-_34207308	16.626	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr16_+_3115312	16.583	NM_001012631 NM_001012633 NM_001012718 NM_004221	IL32	interleukin 32
chr6_-_31704281	16.555		CLIC1	chloride intracellular channel 1
chr6_-_31704093	16.330		CLIC1	chloride intracellular channel 1
chrX_+_64887510	16.256	NM_002444	MSN	moesin
chr10_-_3827205	16.231		KLF6	Kruppel-like factor 6
chr11_+_1889902	16.188	NM_001013253	LSP1	lymphocyte-specific protein 1
chr6_-_31704070	16.146		CLIC1	chloride intracellular channel 1
chr6_+_29910308	16.089		HLA-A	major histocompatibility complex, class I, A
chr1_-_202130677	15.940	NM_001199797 NM_002832	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chrX_+_64887534	15.834		MSN	moesin
chr6_-_31704272	15.832		CLIC1	chloride intracellular channel 1
chr6_-_31704287	15.734		CLIC1	chloride intracellular channel 1
chr16_+_3115638	15.729	NM_001012634	IL32	interleukin 32
chr2_-_43453737	15.600	NM_006887	ZFP36L2	zinc finger protein 36, C3H type-like 2
chr2_-_197036262	15.398		STK17B	serine/threonine kinase 17b
chrX_+_64887593	15.364		MSN	moesin
chr1_+_203274646	15.286	NM_006763	BTG2	BTG family, member 2
chr2_+_233925035	15.286	NM_001017915 NM_005541	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr16_+_3115639	15.180		IL32	interleukin 32
chr5_-_171615320	15.006	NM_005990	STK10	serine/threonine kinase 10
chr6_-_31704304	14.947		CLIC1	chloride intracellular channel 1
chr1_-_183560010	14.809	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr3_-_156878481	14.803	NM_020307	CCNL1	cyclin L1
chr12_-_57504088	14.728	NM_001178079	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr14_-_24616429	14.591		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr13_-_46756295	14.484		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_47655603	14.456		PDZK1IP1	PDZK1 interacting protein 1
chr19_+_50922194	14.218	NM_001243998 NM_001243999 NM_001244000 NM_003121	SPIB	Spi-B transcription factor (Spi-1/PU.1 related)
chr6_-_31704318	13.791	NM_001288	CLIC1	chloride intracellular channel 1
chr2_-_43453146	13.764		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr5_-_171615095	13.642		STK10	serine/threonine kinase 10
chr19_+_45504686	13.436	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr6_+_116692098	13.342	NM_013352	DSE	dermatan sulfate epimerase
chr7_-_150497398	13.207	NM_001101311 NM_001101312 NM_001101314	TMEM176B	transmembrane protein 176B
chr16_+_27325269	13.170		IL4R	interleukin 4 receptor
chr1_-_47655723	13.164	NM_005764	PDZK1IP1	PDZK1 interacting protein 1
chr1_-_183559669	13.146	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr2_-_43453724	13.071		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr2_+_61108702	12.939		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr2_+_233925104	12.749		INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr9_-_110250707	12.521		KLF4	Kruppel-like factor 4 (gut)
chr8_-_103667882	12.489	NM_005655	KLF10	Kruppel-like factor 10
chr14_+_24605393	12.297		PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_-_159895258	12.216		TAGLN2	transgelin 2
chr15_+_89182038	12.099	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr6_+_29855349	12.085		HLA-H	major histocompatibility complex, class I, H (pseudogene)
chr16_+_27325244	12.024	NM_000418 NM_001008699	IL4R	interleukin 4 receptor
chr19_-_2041862	11.915		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr17_+_72462521	11.866	NM_007261	CD300A	CD300a molecule
chr6_+_29894105	11.757
chr19_+_45971249	11.718	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr1_-_27952591	11.664	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr2_+_61108724	11.581	NM_002908	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr2_+_61108775	11.551		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr10_+_30722856	11.533	NM_001244134 NM_005204	MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr2_+_219264477	11.482	NM_021198 NM_182642	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_-_57582152	11.426		CTSZ	cathepsin Z
chr1_-_59248287	11.348		JUN	jun proto-oncogene
chr20_-_4795768	11.335	NM_170774	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr6_+_14117486	11.230	NM_001251901	CD83	CD83 molecule
chr12_-_6716475	11.145		CHD4	chromodomain helicase DNA binding protein 4
chr19_+_1071208	11.007		HMHA1	histocompatibility (minor) HA-1
chr5_-_178054001	10.989	NM_020666	CLK4	CDC-like kinase 4
chr4_+_154605441	10.988		TLR2	toll-like receptor 2
chr19_+_42364322	10.719		RPS19	ribosomal protein S19
chr7_-_105925329	10.633		NAMPT	nicotinamide phosphoribosyltransferase
chr3_+_53195214	10.591	NM_006254 NM_212539	PRKCD	protein kinase C, delta
chr14_+_70078313	10.590		KIAA0247	KIAA0247
chr14_-_24615772	10.563		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr20_+_35202956	10.554	NM_001199535 NM_001199515	TGIF2-C20ORF24 TGIF2	TGIF2-C20orf24 readthrough TGFB-induced factor homeobox 2
chr19_+_859673	10.325		CFD	complement factor D (adipsin)
chr19_+_45251933	10.206	NM_005178	BCL3	B-cell CLL/lymphoma 3
chr19_+_1067114	10.194	NM_012292	HMHA1	histocompatibility (minor) HA-1
chr16_+_53468406	10.188		RBL2	retinoblastoma-like 2 (p130)
chr17_-_40540491	10.160	NM_003150 NM_139276	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
chr19_+_42363987	10.148	NM_001022	RPS19	ribosomal protein S19
chr1_-_202129118	10.124	NM_080588	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr1_-_25256767	10.076	NM_004350	RUNX3	runt-related transcription factor 3
chr14_-_64970319	10.026	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chr11_-_33891485	10.006	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr1_+_26856252	9.968		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_-_89513056	9.804		IGKC	immunoglobulin kappa constant
chr11_-_33891361	9.804	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr4_+_154605421	9.792	NM_003264	TLR2	toll-like receptor 2
chr11_-_57335756	9.734	NM_198183	UBE2L6	ubiquitin-conjugating enzyme E2L 6
chr2_-_197036301	9.706	NM_004226	STK17B	serine/threonine kinase 17b
chr1_-_184943532	9.608		FAM129A	family with sequence similarity 129, member A
chr1_-_202129705	9.599		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr14_+_70078309	9.554	NM_014734	KIAA0247	KIAA0247
chr19_+_4229494	9.515	NM_005755	EBI3	Epstein-Barr virus induced 3
chr17_+_38474513	9.470		RARA	retinoic acid receptor, alpha
chr8_+_144635556	9.453	NM_001166237	GSDMD	gasdermin D
chr1_+_26872306	9.447		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr14_-_24615794	9.337	NM_002818	PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr17_-_40540359	9.268	NM_213662	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
chr12_-_6716550	9.233	NM_001273	CHD4	chromodomain helicase DNA binding protein 4
chr21_+_34775729	9.130		IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_1067293	9.103		HMHA1	histocompatibility (minor) HA-1
chr6_+_37137882	9.032	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr4_-_185395616	9.012	NM_002199	IRF2	interferon regulatory factor 2
chr5_-_142783200	8.899		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_38474544	8.893		RARA	retinoic acid receptor, alpha
chr22_-_37882214	8.736	NM_001166343 NM_002405	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_-_235405692	8.692	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr22_+_22764094	8.687
chr4_-_74964996	8.676	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chr19_+_860615	8.634		CFD	complement factor D (adipsin)
chr1_-_183604885	8.597	NM_005717	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr16_+_81812897	8.592	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr19_+_42364262	8.403		RPS19	ribosomal protein S19
chr10_-_125851850	8.386	NM_014863 NM_015892	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr6_-_29527701	8.359	NM_006398	UBD	ubiquitin D
chr5_-_142783059	8.333		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_-_54813010	8.327	NM_002205	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr17_+_38474472	8.300	NM_001145301 NM_001145302	RARA	retinoic acid receptor, alpha
chr19_-_6591012	8.273		CD70	CD70 molecule
chr21_+_34775189	8.248	NM_005534	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_+_292033	8.247	NM_020185	DUSP22	dual specificity phosphatase 22
chr16_+_81812899	8.182		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr12_+_105501537	8.095		KIAA1033	KIAA1033
chr21_+_34775740	8.069		IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr20_+_44746889	8.059	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr11_+_118307072	7.988	NM_001197104 NM_005933	MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
chr2_+_17935124	7.987	NM_182625	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr17_+_72462766	7.979		CD300A	CD300a molecule
chr11_+_58910173	7.923	NM_001142519 NM_001142520 NM_001142521	FAM111A	family with sequence similarity 111, member A
chr11_-_62446544	7.896		UBXN1	UBX domain protein 1
chr22_-_24059436	7.847
chr19_+_14142459	7.846		IL27RA	interleukin 27 receptor, alpha
chr7_+_150497840	7.798	NM_018487	TMEM176A	transmembrane protein 176A
chr19_-_41859767	7.750		TGFB1	transforming growth factor, beta 1
chr10_-_12085022	7.721	NM_080599	UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)
chr12_-_54813002	7.705		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr4_-_74964836	7.696		CXCL2	chemokine (C-X-C motif) ligand 2
chr19_+_14142611	7.637		IL27RA	interleukin 27 receptor, alpha
chr2_+_10183630	7.616	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr4_-_71532206	7.606		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_-_11688441	7.569		ACP5	acid phosphatase 5, tartrate resistant
chr11_+_67810446	7.559	NM_006053	TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr17_+_16318911	7.548		TRPV2	transient receptor potential cation channel, subfamily V, member 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.31	2.39e-21	GO:0065007	biological regulation
2.50	3.67e-21	GO:0006955	immune response
1.33	5.67e-21	GO:0050789	regulation of biological process
2.11	1.26e-20	GO:0002376	immune system process
1.68	1.49e-20	GO:0048518	positive regulation of biological process
1.34	1.81e-19	GO:0050794	regulation of cellular process
1.68	7.77e-18	GO:0048522	positive regulation of cellular process
1.18	8.42e-18	GO:0009987	cellular process
1.54	1.13e-16	GO:0060255	regulation of macromolecule metabolic process
1.50	1.91e-16	GO:0023052	signaling
2.37	3.99e-16	GO:0002682	regulation of immune system process
1.51	2.43e-15	GO:0007165	signal transduction
1.39	7.60e-15	GO:0043170	macromolecule metabolic process
1.44	1.10e-14	GO:0051716	cellular response to stimulus
1.63	2.20e-14	GO:0048519	negative regulation of biological process
1.45	2.60e-14	GO:0019222	regulation of metabolic process
2.66	2.64e-14	GO:0002684	positive regulation of immune system process
1.48	3.24e-14	GO:0031323	regulation of cellular metabolic process
1.66	4.96e-14	GO:0048523	negative regulation of cellular process
2.16	7.86e-14	GO:0006952	defense response
1.60	8.29e-14	GO:0010556	regulation of macromolecule biosynthetic process
1.31	1.71e-13	GO:0050896	response to stimulus
1.46	4.93e-13	GO:0080090	regulation of primary metabolic process
1.90	1.81e-12	GO:0010604	positive regulation of macromolecule metabolic process
1.56	2.58e-12	GO:0010468	regulation of gene expression
1.53	3.62e-12	GO:0009889	regulation of biosynthetic process
1.54	4.51e-12	GO:0031326	regulation of cellular biosynthetic process
1.67	4.57e-12	GO:0048583	regulation of response to stimulus
1.84	4.71e-12	GO:0009893	positive regulation of metabolic process
1.57	7.26e-12	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.96	9.57e-12	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.37	2.18e-11	GO:0044260	cellular macromolecule metabolic process
1.58	2.37e-11	GO:0042221	response to chemical stimulus
1.57	3.03e-11	GO:0051252	regulation of RNA metabolic process
1.59	4.00e-11	GO:0006355	regulation of transcription, DNA-dependent
1.54	6.40e-11	GO:0006950	response to stress
2.03	9.27e-11	GO:0048584	positive regulation of response to stimulus
2.06	3.03e-10	GO:0010557	positive regulation of macromolecule biosynthetic process
1.80	4.72e-10	GO:0031325	positive regulation of cellular metabolic process
1.27	5.81e-10	GO:0044238	primary metabolic process
2.37	1.11e-09	GO:0050776	regulation of immune response
1.48	2.08e-09	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.07	3.01e-09	GO:0010628	positive regulation of gene expression
1.47	3.44e-09	GO:0051171	regulation of nitrogen compound metabolic process
1.85	8.39e-09	GO:0032774	RNA biosynthetic process
2.45	1.03e-08	GO:0045087	innate immune response
1.71	2.13e-08	GO:0010033	response to organic substance
2.07	2.64e-08	GO:0045893	positive regulation of transcription, DNA-dependent
1.81	3.07e-08	GO:0009605	response to external stimulus
1.86	5.64e-08	GO:0006351	transcription, DNA-dependent
1.81	7.21e-08	GO:0042127	regulation of cell proliferation
1.77	7.75e-08	GO:0043067	regulation of programmed cell death
1.77	8.56e-08	GO:0042981	regulation of apoptosis
1.86	9.44e-08	GO:0009891	positive regulation of biosynthetic process
1.56	1.06e-07	GO:0007166	cell surface receptor linked signaling pathway
1.76	1.18e-07	GO:0010941	regulation of cell death
1.86	1.44e-07	GO:0031328	positive regulation of cellular biosynthetic process
1.22	1.57e-07	GO:0008152	metabolic process
2.71	1.89e-07	GO:0002694	regulation of leukocyte activation
1.39	1.92e-07	GO:0048856	anatomical structure development
2.80	2.01e-07	GO:0051249	regulation of lymphocyte activation
2.66	2.52e-07	GO:0050865	regulation of cell activation
1.34	2.86e-07	GO:0032502	developmental process
1.90	3.08e-07	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.81	3.32e-07	GO:0050793	regulation of developmental process
1.87	4.01e-07	GO:0051173	positive regulation of nitrogen compound metabolic process
2.42	4.53e-07	GO:0031347	regulation of defense response
2.51	4.89e-07	GO:0050778	positive regulation of immune response
1.41	5.43e-07	GO:0048731	system development
2.15	5.60e-07	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.95	6.11e-07	GO:0051254	positive regulation of RNA metabolic process
4.51	8.21e-07	GO:0034138	toll-like receptor 3 signaling pathway
3.01	9.28e-07	GO:0031349	positive regulation of defense response
1.35	1.20e-06	GO:0007275	multicellular organismal development
2.89	1.20e-06	GO:0002764	immune response-regulating signaling pathway
1.51	1.25e-06	GO:0048513	organ development
1.52	1.30e-06	GO:0010467	gene expression
1.38	1.31e-06	GO:0019538	protein metabolic process
2.92	1.42e-06	GO:0045088	regulation of innate immune response
2.88	1.45e-06	GO:0002696	positive regulation of leukocyte activation
2.19	1.67e-06	GO:0007243	intracellular protein kinase cascade
2.19	1.67e-06	GO:0023014	signal transduction via phosphorylation event
4.37	1.69e-06	GO:0002756	MyD88-independent toll-like receptor signaling pathway
2.67	1.87e-06	GO:0002253	activation of immune response
2.89	2.07e-06	GO:0002757	immune response-activating signal transduction
2.83	2.50e-06	GO:0050867	positive regulation of cell activation
1.62	2.78e-06	GO:0051239	regulation of multicellular organismal process
2.33	3.24e-06	GO:0045597	positive regulation of cell differentiation
1.52	3.78e-06	GO:0016070	RNA metabolic process
1.89	3.88e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.53	3.91e-06	GO:0009059	macromolecule biosynthetic process
1.53	4.42e-06	GO:0034645	cellular macromolecule biosynthetic process
1.90	4.52e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
2.01	4.57e-06	GO:0045892	negative regulation of transcription, DNA-dependent
2.00	5.21e-06	GO:0051253	negative regulation of RNA metabolic process
1.91	5.34e-06	GO:0071310	cellular response to organic substance
3.04	5.46e-06	GO:0002252	immune effector process
1.87	5.47e-06	GO:0009890	negative regulation of biosynthetic process
1.75	5.61e-06	GO:0031324	negative regulation of cellular metabolic process
2.86	7.32e-06	GO:0051251	positive regulation of lymphocyte activation
1.72	8.50e-06	GO:0070887	cellular response to chemical stimulus
3.90	1.01e-05	GO:0008063	Toll signaling pathway
3.90	1.01e-05	GO:0034142	toll-like receptor 4 signaling pathway
2.41	1.30e-05	GO:0001817	regulation of cytokine production
1.90	1.60e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.21	1.84e-05	GO:0044237	cellular metabolic process
1.90	1.89e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.31	2.07e-05	GO:0034097	response to cytokine stimulus
1.71	2.08e-05	GO:0010605	negative regulation of macromolecule metabolic process
2.08	2.14e-05	GO:0032583	regulation of gene-specific transcription
3.63	2.46e-05	GO:0002224	toll-like receptor signaling pathway
1.67	2.59e-05	GO:0006793	phosphorus metabolic process
1.67	2.59e-05	GO:0006796	phosphate metabolic process
1.80	2.91e-05	GO:0006468	protein phosphorylation
3.49	3.15e-05	GO:0002758	innate immune response-activating signal transduction
1.97	3.28e-05	GO:0080134	regulation of response to stress
1.56	3.30e-05	GO:0035556	intracellular signal transduction
2.17	3.55e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
3.94	3.72e-05	GO:0034130	toll-like receptor 1 signaling pathway
3.94	3.72e-05	GO:0034134	toll-like receptor 2 signaling pathway
1.88	4.39e-05	GO:0010629	negative regulation of gene expression
2.54	4.59e-05	GO:0071345	cellular response to cytokine stimulus
1.86	4.80e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.10	4.98e-05	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.96	5.08e-05	GO:0006935	chemotaxis
1.96	5.08e-05	GO:0042330	taxis
3.42	5.15e-05	GO:0002218	activation of innate immune response
1.52	5.46e-05	GO:0009653	anatomical structure morphogenesis
1.54	6.31e-05	GO:0009966	regulation of signal transduction
1.36	6.40e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.02	6.51e-05	GO:0051094	positive regulation of developmental process
1.77	6.70e-05	GO:2000026	regulation of multicellular organismal development
3.06	6.74e-05	GO:0045089	positive regulation of innate immune response
3.47	6.89e-05	GO:0002221	pattern recognition receptor signaling pathway
1.66	7.05e-05	GO:0009892	negative regulation of metabolic process
2.30	7.11e-05	GO:0051270	regulation of cellular component movement
1.63	7.15e-05	GO:0010646	regulation of cell communication
1.38	7.44e-05	GO:0044267	cellular protein metabolic process
1.94	8.01e-05	GO:0008284	positive regulation of cell proliferation
1.40	1.17e-04	GO:0090304	nucleic acid metabolic process
3.72	1.18e-04	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
2.68	1.21e-04	GO:0050863	regulation of T cell activation
1.79	1.31e-04	GO:0045595	regulation of cell differentiation
1.69	1.71e-04	GO:0040011	locomotion
3.41	1.92e-04	GO:0002443	leukocyte mediated immunity
2.55	2.03e-04	GO:0019221	cytokine-mediated signaling pathway
2.36	2.07e-04	GO:0045321	leukocyte activation
1.47	2.43e-04	GO:0023051	regulation of signaling
1.44	2.54e-04	GO:0006464	protein modification process
1.58	4.71e-04	GO:0051246	regulation of protein metabolic process
2.63	6.96e-04	GO:0051272	positive regulation of cellular component movement
3.50	7.51e-04	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.76	7.75e-04	GO:0050870	positive regulation of T cell activation
1.59	8.90e-04	GO:0032268	regulation of cellular protein metabolic process
1.60	9.63e-04	GO:0032879	regulation of localization
1.82	1.01e-03	GO:0006928	cellular component movement
1.65	1.05e-03	GO:0016310	phosphorylation
1.29	1.07e-03	GO:0006807	nitrogen compound metabolic process
2.17	1.13e-03	GO:0040012	regulation of locomotion
1.40	1.21e-03	GO:0043412	macromolecule modification
3.41	1.23e-03	GO:0002250	adaptive immune response
1.62	1.39e-03	GO:0051704	multi-organism process
1.47	1.51e-03	GO:0065009	regulation of molecular function
1.93	1.88e-03	GO:0040008	regulation of growth
1.28	1.96e-03	GO:0016043	cellular component organization
2.44	1.98e-03	GO:0070201	regulation of establishment of protein localization
2.65	2.11e-03	GO:0007568	aging
1.84	2.15e-03	GO:0009967	positive regulation of signal transduction
1.88	2.33e-03	GO:0060548	negative regulation of cell death
2.19	2.43e-03	GO:0030334	regulation of cell migration
1.63	2.52e-03	GO:0051128	regulation of cellular component organization
2.61	2.89e-03	GO:0002237	response to molecule of bacterial origin
2.61	2.89e-03	GO:0034762	regulation of transmembrane transport
5.11	3.35e-03	GO:0042345	regulation of NF-kappaB import into nucleus
2.17	3.42e-03	GO:2000145	regulation of cell motility
2.68	3.74e-03	GO:0032496	response to lipopolysaccharide
1.88	3.82e-03	GO:0043069	negative regulation of programmed cell death
1.63	3.89e-03	GO:0031399	regulation of protein modification process
1.62	4.28e-03	GO:0044093	positive regulation of molecular function
3.29	4.30e-03	GO:0002699	positive regulation of immune effector process
1.33	4.33e-03	GO:0044249	cellular biosynthetic process
2.17	4.39e-03	GO:0009617	response to bacterium
3.40	4.62e-03	GO:0002449	lymphocyte mediated immunity
3.16	4.85e-03	GO:0042306	regulation of protein import into nucleus
2.45	5.25e-03	GO:0051223	regulation of protein transport
2.96	5.52e-03	GO:0046822	regulation of nucleocytoplasmic transport
2.49	5.72e-03	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.87	5.79e-03	GO:0043066	negative regulation of apoptosis
2.34	5.81e-03	GO:0046649	lymphocyte activation
1.78	5.87e-03	GO:0010647	positive regulation of cell communication
1.20	6.67e-03	GO:0032501	multicellular organismal process
8.64	6.75e-03	GO:0002828	regulation of type 2 immune response
1.77	7.35e-03	GO:0023056	positive regulation of signaling
1.35	7.95e-03	GO:0048869	cellular developmental process
2.76	8.04e-03	GO:0032386	regulation of intracellular transport
1.32	8.42e-03	GO:0009058	biosynthetic process
2.04	8.78e-03	GO:0051130	positive regulation of cellular component organization
1.36	8.86e-03	GO:0030154	cell differentiation
2.09	9.12e-03	GO:0010740	positive regulation of intracellular protein kinase cascade
2.47	9.59e-03	GO:0040017	positive regulation of locomotion
1.66	1.01e-02	GO:0042325	regulation of phosphorylation
1.56	1.02e-02	GO:0009611	response to wounding
1.95	1.11e-02	GO:0007389	pattern specification process
2.15	1.30e-02	GO:0001558	regulation of cell growth
1.27	1.36e-02	GO:0034641	cellular nitrogen compound metabolic process
1.25	1.37e-02	GO:0071840	cellular component organization or biogenesis
3.78	1.38e-02	GO:0051403	stress-activated MAPK cascade
2.89	1.39e-02	GO:0033157	regulation of intracellular protein transport
2.56	1.40e-02	GO:0001819	positive regulation of cytokine production
1.76	1.54e-02	GO:0001775	cell activation
2.21	1.56e-02	GO:0043193	positive regulation of gene-specific transcription
1.33	1.60e-02	GO:0065008	regulation of biological quality
3.39	1.74e-02	GO:0060333	interferon-gamma-mediated signaling pathway
2.20	1.75e-02	GO:0032880	regulation of protein localization
2.83	2.01e-02	GO:0032103	positive regulation of response to external stimulus
1.66	2.03e-02	GO:0001932	regulation of protein phosphorylation
3.47	2.34e-02	GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2.73	2.35e-02	GO:0070663	regulation of leukocyte proliferation
3.17	2.50e-02	GO:0051092	positive regulation of NF-kappaB transcription factor activity
2.11	2.59e-02	GO:0003002	regionalization
1.62	3.08e-02	GO:0019220	regulation of phosphate metabolic process
1.62	3.08e-02	GO:0051174	regulation of phosphorus metabolic process
2.62	3.14e-02	GO:0090047	positive regulation of transcription regulator activity
2.02	3.77e-02	GO:0051101	regulation of DNA binding
2.72	4.03e-02	GO:0050670	regulation of lymphocyte proliferation
2.38	4.05e-02	GO:0030335	positive regulation of cell migration
2.38	4.05e-02	GO:2000147	positive regulation of cell motility
2.10	4.13e-02	GO:0032101	regulation of response to external stimulus
2.05	4.19e-02	GO:0090046	regulation of transcription regulator activity
1.71	4.60e-02	GO:0009607	response to biotic stimulus
2.33	4.72e-02	GO:0009952	anterior/posterior pattern formation
2.69	4.76e-02	GO:0032944	regulation of mononuclear cell proliferation
3.29	4.80e-02	GO:0050864	regulation of B cell activation
2.76	4.91e-02	GO:0030198	extracellular matrix organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.30	8.12e-12	GO:0005634	nucleus
1.11	3.81e-06	GO:0044424	intracellular part
1.10	5.96e-06	GO:0005622	intracellular
1.52	3.79e-05	GO:0005654	nucleoplasm
1.14	7.79e-05	GO:0043231	intracellular membrane-bounded organelle
1.39	9.37e-05	GO:0005829	cytosol
1.13	9.67e-05	GO:0043227	membrane-bounded organelle
1.11	1.68e-03	GO:0043229	intracellular organelle
1.11	1.81e-03	GO:0043226	organelle
1.36	2.10e-03	GO:0031981	nuclear lumen
1.57	2.38e-03	GO:0005615	extracellular space
1.32	4.54e-03	GO:0044428	nuclear part
1.30	9.85e-03	GO:0070013	intracellular organelle lumen
1.30	1.12e-02	GO:0044459	plasma membrane part
1.45	1.14e-02	GO:0044421	extracellular region part
1.29	1.29e-02	GO:0043233	organelle lumen
1.28	1.37e-02	GO:0031974	membrane-enclosed lumen
1.40	1.95e-02	GO:0005887	integral to plasma membrane
1.39	2.02e-02	GO:0031226	intrinsic to plasma membrane
3.77	3.53e-02	GO:0005581	collagen
1.73	3.72e-02	GO:0009986	cell surface
2.24	4.56e-02	GO:0009897	external side of plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.30	3.75e-18	GO:0005515	protein binding
1.15	3.42e-14	GO:0005488	binding
1.93	3.35e-12	GO:0001071	nucleic acid binding transcription factor activity
1.93	3.35e-12	GO:0003700	sequence-specific DNA binding transcription factor activity
2.04	6.70e-10	GO:0043565	sequence-specific DNA binding
1.79	4.85e-09	GO:0030528	transcription regulator activity
1.36	1.27e-04	GO:0003677	DNA binding
2.40	6.79e-04	GO:0005126	cytokine receptor binding
4.32	1.08e-03	GO:0003823	antigen binding
2.00	1.19e-03	GO:0016563	transcription activator activity
1.63	1.71e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.68	2.39e-03	GO:0004672	protein kinase activity
3.66	2.45e-03	GO:0004879	ligand-dependent nuclear receptor activity
1.25	4.50e-03	GO:0003676	nucleic acid binding
1.56	5.97e-03	GO:0016301	kinase activity
1.77	7.44e-03	GO:0004674	protein serine/threonine kinase activity
1.57	8.13e-03	GO:0019899	enzyme binding
1.94	8.86e-03	GO:0008134	transcription factor binding
2.10	2.57e-02	GO:0010843	promoter binding
3.39	2.58e-02	GO:0003707	steroid hormone receptor activity