Motif ID: NKX3-1.p2

Z-value: 0.959


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_23540401-0.244.6e-04Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_88896838 35.720 SPP1
secreted phosphoprotein 1
chr4_+_88896801 35.615 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr4_+_88896899 35.370 SPP1
secreted phosphoprotein 1
chr4_+_88896868 35.111 SPP1
secreted phosphoprotein 1
chr14_+_67831484 14.643 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_+_228356287 13.411 AGFG1
ArfGAP with FG repeats 1
chr21_-_27253197 12.262 APP
amyloid beta (A4) precursor protein
chr10_+_112344076 11.991 SMC3
structural maintenance of chromosomes 3
chr18_+_72167021 11.732 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr7_+_45933096 10.469


chrX_+_114827818 9.615 NM_001136025
NM_001172335
PLS3

plastin 3

chr12_+_50869531 9.127 LARP4
La ribonucleoprotein domain family, member 4
chr10_-_118680978 9.084 KIAA1598
KIAA1598
chr3_-_149086884 8.888 TM4SF1
transmembrane 4 L six family member 1
chr9_-_124922049 8.652 NM_014222
NDUFA8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr9_-_124921981 8.574 NDUFA8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr3_+_158991035 8.471 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr14_-_75600111 7.831 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr1_+_236557643 7.385 NM_145861
EDARADD
EDAR-associated death domain
chr11_+_118257222 7.172 UBE4A
ubiquitination factor E4A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
4.80 2.60e-05 GO:0007156 homophilic cell adhesion
3.44 1.32e-05 GO:0016337 cell-cell adhesion
1.19 3.42e-05 GO:0009987 cellular process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.05 7.80e-03 GO:0005509 calcium ion binding
1.20 4.55e-02 GO:0005515 protein binding
1.13 2.99e-03 GO:0005488 binding