Motif ID: NR1H4.p2

Z-value: 2.017


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
NR1H4 9971 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR1H4chr12_+_1008971370.558.4e-19Click!


Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_21945031 49.643 NM_032846
RAB2B
RAB2B, member RAS oncogene family
chr9_+_74526527 41.062 C9orf85
chromosome 9 open reading frame 85
chr5_-_149792276 39.337 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr1_+_152635871 38.373 NM_178430
LCE2D
late cornified envelope 2D
chr14_-_106111114 38.072 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr17_+_1665233 37.482 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665306 36.685 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665281 36.198 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_106092256 35.534 IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr17_+_1665342 34.868 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_+_55464605 34.801 NM_057176
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr3_-_49158357 31.317 NM_001199160
NM_001199161
NM_001199162
NM_006677
USP19



ubiquitin specific peptidase 19



chr20_-_44455932 30.912 NM_003279
TNNC2
troponin C type 2 (fast)
chr5_-_139943829 30.647 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr14_-_106237675 28.895 IGHM
immunoglobulin heavy constant mu
chr3_-_49158171 28.677 USP19
ubiquitin specific peptidase 19
chr19_+_35629727 28.664 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr16_+_69166538 28.231 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr11_+_45868956 27.564 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr5_-_139944045 27.245 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
2.91 3.33e-02 GO:0007586 digestion
2.47 2.15e-03 GO:0003013 circulatory system process
2.47 2.15e-03 GO:0008015 blood circulation
2.21 3.72e-02 GO:0071345 cellular response to cytokine stimulus
2.18 1.80e-03 GO:0034097 response to cytokine stimulus
1.60 5.05e-03 GO:0042127 regulation of cell proliferation
1.54 4.88e-02 GO:0070887 cellular response to chemical stimulus
1.39 1.23e-02 GO:0048583 regulation of response to stimulus
1.39 2.20e-02 GO:0007166 cell surface receptor linked signaling pathway
1.38 3.93e-03 GO:0065008 regulation of biological quality
1.34 3.57e-06 GO:0023052 signaling
1.34 7.25e-05 GO:0007165 signal transduction
1.34 2.46e-02 GO:0042221 response to chemical stimulus
1.29 1.11e-04 GO:0051716 cellular response to stimulus
1.23 1.27e-09 GO:0065007 biological regulation
1.23 3.44e-05 GO:0050896 response to stimulus
1.22 2.76e-07 GO:0050789 regulation of biological process
1.20 1.01e-04 GO:0050794 regulation of cellular process
1.10 1.13e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.61 6.78e-06 GO:0005887 integral to plasma membrane
1.60 3.63e-03 GO:0005615 extracellular space
1.58 2.14e-05 GO:0031226 intrinsic to plasma membrane
1.47 1.77e-02 GO:0044421 extracellular region part
1.45 2.52e-06 GO:0044459 plasma membrane part
1.36 2.63e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
5.13 4.04e-05 GO:0003823 antigen binding
1.99 2.50e-02 GO:0032403 protein complex binding
1.74 4.02e-02 GO:0008289 lipid binding