Motif ID: NR3C1.p2

Z-value: 1.310


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR3C1chr5_-_142783059-0.291.4e-05Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_91572328 24.933 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr21_-_46340776 22.777 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_+_73358593 22.081 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr21_-_46340821 22.046 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr7_+_23286390 21.590 GPNMB
glycoprotein (transmembrane) nmb
chr22_+_22712091 20.863 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr7_+_23286386 20.799 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286384 20.616 GPNMB
glycoprotein (transmembrane) nmb
chr3_-_187463227 20.574 BCL6
B-cell CLL/lymphoma 6
chr2_-_237172987 19.131 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr7_+_20655244 18.844 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr19_-_36643770 18.811 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr10_+_70847817 17.450 NM_002727
SRGN
serglycin
chr7_-_124405029 15.140 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr8_-_110655418 14.435 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr17_-_8055684 13.099 NM_002616
PER1
period homolog 1 (Drosophila)
chr6_-_6320875 12.916 F13A1
coagulation factor XIII, A1 polypeptide
chr1_+_44115804 12.884 KDM4A
lysine (K)-specific demethylase 4A
chrY_+_16168097 12.744 NM_181880
NM_004679
VCY1B
VCX3A
VCY
variable charge, Y-linked 1B
variable charge, X-linked 3A
variable charge, Y-linked
chr19_+_15783827 12.527 NM_023944
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.77 3.70e-02 GO:0006954 inflammatory response
2.52 3.32e-06 GO:0006955 immune response
2.47 3.66e-03 GO:0001775 cell activation
2.47 1.07e-02 GO:0050776 regulation of immune response
2.27 5.70e-08 GO:0002376 immune system process
2.16 3.94e-02 GO:0042060 wound healing
2.09 4.44e-03 GO:0006952 defense response
2.07 2.02e-03 GO:0009611 response to wounding
1.28 1.25e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.30 3.64e-02 GO:0009897 external side of plasma membrane
2.02 2.01e-03 GO:0005615 extracellular space
1.81 7.43e-03 GO:0044421 extracellular region part
1.76 4.11e-03 GO:0005887 integral to plasma membrane
1.75 3.63e-03 GO:0031226 intrinsic to plasma membrane
1.53 4.97e-03 GO:0044459 plasma membrane part
1.49 3.20e-02 GO:0005576 extracellular region
1.47 7.72e-06 GO:0005886 plasma membrane
1.46 6.94e-06 GO:0071944 cell periphery
1.19 3.73e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
7.89 4.86e-04 GO:0003823 antigen binding