Motif ID: ONECUT1,2.p2

Z-value: 1.167


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
ONECUT1 3175 one cut homeobox 1
ONECUT2 9480 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ONECUT1chr15_-_530820870.243.7e-04Click!
ONECUT2chr18_+_551027770.018.5e-01Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_149792370 23.356 NM_001025158
NM_001025159
NM_004355
 CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr5_-_149792276 22.253 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr22_+_23054862 21.123 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr2_-_89165652 19.592


chr6_+_33043702 17.127 NM_002121
 HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr12_-_91573264 12.204 NM_133503
 DCN
decorin
chr1_+_198608136 10.708 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr7_+_23286420 10.501 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286384 10.258 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_151345156 10.167 NM_003944
 SELENBP1
selenium binding protein 1
chr10_-_98031154 10.006 NM_001114094
NM_013314
 BLNK

B-cell linker

chr4_-_100212085 9.978 NM_000667
 ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr1_+_198608244 9.940 PTPRC
protein tyrosine phosphatase, receptor type, C
chr18_-_47814691 9.733 NM_001101654
NM_014593
 CXXC1

CXXC finger protein 1

chr15_-_43513024 9.701 EPB42
erythrocyte membrane protein band 4.2
chr1_+_198608216 8.660 PTPRC
protein tyrosine phosphatase, receptor type, C
chr15_-_43513234 8.573 NM_000119
NM_001114134
 EPB42

erythrocyte membrane protein band 4.2

chr7_-_14025826 8.369 NM_001163150
NM_001163151
NM_001163152
 ETV1


ets variant 1


chr8_-_82395401 8.331 NM_001442
 FABP4
fatty acid binding protein 4, adipocyte
chr3_-_141747434 8.277 NM_001178141
NM_001178142
NM_006286
 TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.14 3.44e-05 GO:0006955 immune response
2.12 3.13e-02 GO:0050776 regulation of immune response
2.10 6.81e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
1.79 2.74e-04 GO:0002376 immune system process
1.57 1.95e-03 GO:0048513 organ development
1.50 3.24e-02 GO:0007166 cell surface receptor linked signaling pathway
1.37 1.69e-03 GO:0032502 developmental process
1.35 1.32e-05 GO:0032501 multicellular organismal process
1.35 3.96e-03 GO:0023052 signaling
1.35 1.47e-02 GO:0007275 multicellular organismal development
1.35 1.83e-02 GO:0007165 signal transduction
1.35 4.89e-02 GO:0048856 anatomical structure development
1.31 1.21e-02 GO:0051716 cellular response to stimulus
1.30 2.86e-05 GO:0050896 response to stimulus
1.22 1.97e-03 GO:0050789 regulation of biological process
1.21 1.27e-03 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
12.15 4.88e-02 GO:0042589 zymogen granule membrane
8.68 4.77e-02 GO:0042613 MHC class II protein complex
1.83 8.44e-05 GO:0044421 extracellular region part
1.83 2.42e-03 GO:0005615 extracellular space
1.66 1.37e-03 GO:0005887 integral to plasma membrane
1.65 1.50e-03 GO:0031226 intrinsic to plasma membrane
1.59 1.46e-05 GO:0005576 extracellular region
1.48 8.94e-04 GO:0044459 plasma membrane part
1.27 1.32e-02 GO:0071944 cell periphery
1.27 1.59e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
4.97 2.74e-02 GO:0043498 cell surface binding