Motif ID: PAX4.p2

Z-value: 1.428


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX4chr7_-_127255574-0.054.7e-01Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_176733413 58.417 GPM6A
glycoprotein M6A
chr4_-_176733901 36.478 GPM6A
glycoprotein M6A
chr1_+_151032150 25.694 NM_006818
 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032880 24.456 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chrX_+_135067634 24.379 SLC9A6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr1_+_151032683 24.185 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chrX_+_135067573 20.808 NM_001177651
NM_001042537
NM_006359
 SLC9A6


solute carrier family 9 (sodium/hydrogen exchanger), member 6


chrX_+_103031753 20.668 NM_000533
NM_199478
 PLP1

proteolipid protein 1

chr6_+_32407618 19.718 NM_019111
 HLA-DRA
major histocompatibility complex, class II, DR alpha
chr8_+_41348105 19.687 GOLGA7
golgin A7
chr8_+_41348126 18.989 NM_001002296
 GOLGA7
golgin A7
chr15_+_66694216 18.753 MAP2K1
mitogen-activated protein kinase kinase 1
chr8_+_41348094 18.442 GOLGA7
golgin A7
chrX_+_103031433 17.836 NM_001128834
 PLP1
proteolipid protein 1
chr12_-_16759531 16.709 NM_018640
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_-_8063946 16.339 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_-_1623942 16.203 SLC35E2B
SLC35E2
solute carrier family 35, member E2B
solute carrier family 35, member E2
chr11_-_62474666 15.319 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_15528324 14.607 NM_033201
 C16orf45
chromosome 16 open reading frame 45
chr11_-_62474869 14.393 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 57 entries
enrichment   p-value GO term description
20.50 2.19e-03 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
18.22 4.81e-03 GO:0048880 sensory system development
18.22 4.81e-03 GO:0048892 lateral line nerve development
18.22 4.81e-03 GO:0048895 lateral line nerve glial cell differentiation
18.22 4.81e-03 GO:0048925 lateral line system development
18.22 4.81e-03 GO:0048937 lateral line nerve glial cell development
18.22 4.81e-03 GO:0050935 iridophore differentiation
14.91 1.68e-02 GO:0060600 dichotomous subdivision of an epithelial terminal unit
13.66 2.80e-02 GO:0048846 axon extension involved in axon guidance
13.66 2.80e-02 GO:0090184 positive regulation of kidney development
13.12 5.03e-03 GO:0048485 sympathetic nervous system development
7.98 1.99e-03 GO:0021782 glial cell development
7.16 1.20e-04 GO:0019882 antigen processing and presentation
4.59 7.53e-03 GO:0050851 antigen receptor-mediated signaling pathway
4.55 3.59e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
4.37 5.75e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
4.03 9.24e-05 GO:0002757 immune response-activating signal transduction
3.94 1.38e-04 GO:0002764 immune response-regulating signaling pathway
3.39 9.66e-04 GO:0002253 activation of immune response
3.15 3.97e-04 GO:0050778 positive regulation of immune response

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
11.71 1.16e-02 GO:0042613 MHC class II protein complex
9.22 8.80e-05 GO:0042611 MHC protein complex
1.58 5.96e-04 GO:0044459 plasma membrane part
1.52 8.91e-03 GO:0005829 cytosol
1.29 4.19e-02 GO:0071944 cell periphery
1.26 3.77e-03 GO:0044444 cytoplasmic part
1.22 2.55e-04 GO:0005737 cytoplasm
1.06 9.14e-03 GO:0044464 cell part
1.06 9.29e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
24.59 4.39e-02 GO:0004062 aryl sulfotransferase activity
7.38 9.72e-04 GO:0003823 antigen binding
3.89 1.37e-03 GO:0003690 double-stranded DNA binding
3.19 5.67e-03 GO:0043566 structure-specific DNA binding