Motif ID: PAX5.p2

Z-value: 1.884


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37034358-0.714.1e-35Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_2950593 35.367 NM_003311
 PHLDA2
pleckstrin homology-like domain, family A, member 2
chr6_-_4135701 32.301 NM_001166010
NM_006117
NM_206836
 ECI2


enoyl-CoA delta isomerase 2


chr2_+_235860616 31.114 NM_014521
 SH3BP4
SH3-domain binding protein 4
chr16_+_1359653 30.440 UBE2I
ubiquitin-conjugating enzyme E2I
chrX_+_133594171 30.367 NM_000194
 HPRT1
hypoxanthine phosphoribosyltransferase 1
chr16_+_1359636 30.227 UBE2I
ubiquitin-conjugating enzyme E2I
chr16_+_1359692 29.497 UBE2I
ubiquitin-conjugating enzyme E2I
chr20_+_388941 28.866 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chrX_+_133594225 28.771 HPRT1
hypoxanthine phosphoribosyltransferase 1
chr16_+_1359673 28.224 UBE2I
ubiquitin-conjugating enzyme E2I
chr2_-_215674292 25.640 NM_000465
 BARD1
BRCA1 associated RING domain 1
chr3_-_185542807 24.497 NM_001007225
NM_006548
 IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr2_-_179315756 24.307 NM_003690
 PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr19_-_291168 24.239 NM_177543
 PPAP2C
phosphatidic acid phosphatase type 2C
chr4_+_57302268 24.143 NM_001079524
NM_001079525
 PAICS

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

chr7_+_26241281 23.174 NM_016587
 CBX3
chromobox homolog 3
chrX_+_118602391 22.937 SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr20_+_62371218 22.762 SLC2A4RG
SLC2A4 regulator
chr7_-_105752650 22.615 SYPL1
synaptophysin-like 1
chr20_+_62371109 22.556 NM_020062
 SLC2A4RG
SLC2A4 regulator

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 280 entries
enrichment   p-value GO term description
2.10 1.14e-02 GO:0006921 cellular component disassembly involved in apoptosis
1.99 2.08e-02 GO:0008629 induction of apoptosis by intracellular signals
1.95 3.11e-02 GO:0051656 establishment of organelle localization
1.91 9.74e-05 GO:0000082 G1/S transition of mitotic cell cycle
1.91 6.38e-03 GO:0010720 positive regulation of cell development
1.89 3.57e-04 GO:0008286 insulin receptor signaling pathway
1.80 1.29e-04 GO:0032869 cellular response to insulin stimulus
1.78 2.13e-02 GO:0051789 response to protein stimulus
1.74 2.65e-07 GO:0006366 transcription from RNA polymerase II promoter
1.74 5.02e-03 GO:0071496 cellular response to external stimulus
1.72 8.25e-05 GO:0032868 response to insulin stimulus
1.71 1.94e-04 GO:0071375 cellular response to peptide hormone stimulus
1.71 1.11e-02 GO:0031400 negative regulation of protein modification process
1.68 4.47e-06 GO:0051325 interphase
1.68 6.28e-06 GO:0051329 interphase of mitotic cell cycle
1.66 2.23e-06 GO:0043434 response to peptide hormone stimulus
1.65 1.97e-04 GO:0009166 nucleotide catabolic process
1.64 1.68e-04 GO:0007346 regulation of mitotic cell cycle
1.63 2.41e-06 GO:0044419 interspecies interaction between organisms
1.63 5.44e-05 GO:0032870 cellular response to hormone stimulus

Gene overrepresentation in compartment category:

Showing 1 to 20 of 70 entries
enrichment   p-value GO term description
3.04 1.40e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.97 4.29e-02 GO:0000307 cyclin-dependent protein kinase holoenzyme complex
2.70 4.45e-03 GO:0001725 stress fiber
2.67 9.44e-04 GO:0042641 actomyosin
2.52 1.77e-02 GO:0032432 actin filament bundle
2.22 2.31e-06 GO:0042470 melanosome
2.22 2.31e-06 GO:0048770 pigment granule
2.20 2.99e-02 GO:0017053 transcriptional repressor complex
2.14 4.39e-03 GO:0030496 midbody
1.90 1.04e-04 GO:0019867 outer membrane
1.89 5.03e-03 GO:0016585 chromatin remodeling complex
1.86 5.27e-04 GO:0031968 organelle outer membrane
1.85 5.04e-03 GO:0005741 mitochondrial outer membrane
1.79 4.79e-04 GO:0031965 nuclear membrane
1.79 8.98e-03 GO:0030055 cell-substrate junction
1.78 1.68e-02 GO:0005924 cell-substrate adherens junction
1.78 2.36e-02 GO:0005925 focal adhesion
1.75 7.97e-04 GO:0005912 adherens junction
1.74 1.42e-06 GO:0005635 nuclear envelope
1.71 8.61e-04 GO:0070161 anchoring junction

Gene overrepresentation in function category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
1.97 8.19e-03 GO:0031625 ubiquitin protein ligase binding
1.78 4.17e-02 GO:0051427 hormone receptor binding
1.65 1.38e-02 GO:0004721 phosphoprotein phosphatase activity
1.63 8.18e-04 GO:0003713 transcription coactivator activity
1.58 2.98e-06 GO:0000988 protein binding transcription factor activity
1.58 2.98e-06 GO:0000989 transcription factor binding transcription factor activity
1.57 4.78e-06 GO:0003712 transcription cofactor activity
1.54 1.96e-06 GO:0019904 protein domain specific binding
1.49 1.32e-09 GO:0042802 identical protein binding
1.48 1.08e-04 GO:0042803 protein homodimerization activity
1.47 1.59e-02 GO:0008134 transcription factor binding
1.46 1.74e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.45 3.29e-08 GO:0019899 enzyme binding
1.41 3.83e-02 GO:0042578 phosphoric ester hydrolase activity
1.40 4.68e-05 GO:0046983 protein dimerization activity
1.33 2.29e-04 GO:0003723 RNA binding
1.32 5.43e-79 GO:0005515 protein binding
1.32 4.78e-02 GO:0008092 cytoskeletal protein binding
1.28 4.22e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.27 2.90e-10 GO:0000166 nucleotide binding