Motif ID: PBX1.p2

Z-value: 1.380


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PBX1chr1_+_164528914-0.468.5e-13Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_28241233 39.561 NM_002946
RPA2
replication protein A2, 32kDa
chr5_+_162864571 39.419 NM_004060
NM_199246
CCNG1

cyclin G1

chr9_+_140135698 34.638 NM_006088
TUBB4B
tubulin, beta 4B class IVb
chrX_+_119737743 34.563 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr9_+_140135738 32.071 TUBB4B
tubulin, beta 4B class IVb
chr17_+_8191814 32.011 NM_001177801
NM_001177802
NM_016492
RANGRF


RAN guanine nucleotide release factor


chr7_-_7680048 28.893 RPA3
replication protein A3, 14kDa
chr4_-_174255454 27.727 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chrX_+_119737905 27.551 MCTS1
malignant T cell amplified sequence 1
chr9_+_140135742 26.285 TUBB4B
tubulin, beta 4B class IVb
chrX_+_119737984 25.573 MCTS1
malignant T cell amplified sequence 1
chr12_+_64803741 25.371 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr3_-_32544358 24.483 NM_017801
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr12_+_49658862 23.896 NM_032704
TUBA1C
tubulin, alpha 1c
chr3_+_172468469 23.418 ECT2
epithelial cell transforming sequence 2 oncogene
chr6_+_111195986 23.367 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr6_-_75965845 22.639 TMEM30A
transmembrane protein 30A
chr1_-_28240953 22.607 RPA2
replication protein A2, 32kDa
chr12_+_49658865 22.297 TUBA1C
tubulin, alpha 1c
chr2_+_216986817 21.728 XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chrX_+_123234462 21.067 STAG2
stromal antigen 2
chr5_-_89705477 20.806 NM_004365
CETN3
centrin, EF-hand protein, 3
chr15_-_64673569 20.598 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr10_+_102123420 20.238


chr6_-_27114577 19.844 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr17_-_38821286 19.509 NM_152349
KRT222
keratin 222
chr6_+_149721494 19.205 NM_001002255
SUMO4
SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
chr20_+_44441334 18.793 UBE2C
ubiquitin-conjugating enzyme E2C
chr6_+_27114860 18.726 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr14_+_64971504 18.509 ZBTB1
zinc finger and BTB domain containing 1
chr5_+_44808967 18.489 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr10_+_14880335 17.080 HSPA14
heat shock 70kDa protein 14
chr3_-_129158675 17.074 MBD4
methyl-CpG binding domain protein 4
chr3_-_32544319 16.944 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr3_-_129158849 16.754 NM_003925
MBD4
methyl-CpG binding domain protein 4
chr3_-_129158779 16.686 MBD4
methyl-CpG binding domain protein 4
chr3_-_33481877 16.463 NM_001128161
UBP1
upstream binding protein 1 (LBP-1a)
chr1_+_155278727 16.421 FDPS
farnesyl diphosphate synthase
chr3_-_33481862 16.149 NM_001128160
NM_014517
UBP1

upstream binding protein 1 (LBP-1a)

chr19_+_14640413 15.973 TECR
trans-2,3-enoyl-CoA reductase
chr1_+_155278677 15.937 NM_001135821
FDPS
farnesyl diphosphate synthase
chr10_+_14880343 15.874 HSPA14
heat shock 70kDa protein 14
chr3_+_38206968 15.805 NM_005109
OXSR1
oxidative-stress responsive 1
chr1_-_115268890 15.203 CSDE1
cold shock domain containing E1, RNA-binding
chr19_+_54619149 15.115 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr3_+_156394452 14.967 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr3_+_179280738 14.858 ACTL6A
actin-like 6A
chr8_-_101965554 14.837 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_-_179044835 14.764 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr13_+_53035227 14.732 CKAP2
cytoskeleton associated protein 2
chr10_+_14880137 14.528 NM_016299
HSPA14
heat shock 70kDa protein 14
chr5_+_145826866 14.415 NM_001040006
NM_006706
TCERG1

transcription elongation regulator 1

chr8_-_101965096 14.375 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_-_120638894 14.247 RPLP0
ribosomal protein, large, P0
chr7_-_140179224 14.197 MKRN1
makorin ring finger protein 1
chr20_+_44441247 14.104 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr19_+_14640406 13.656 TECR
trans-2,3-enoyl-CoA reductase
chr2_-_47134945 13.253 MCFD2
multiple coagulation factor deficiency 2
chr12_-_120638909 13.023 RPLP0
ribosomal protein, large, P0
chr8_-_25315941 12.622 NM_017634
KCTD9
potassium channel tetramerisation domain containing 9
chr1_+_151227209 12.507 PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr11_+_95523608 12.426 NM_001243776
NM_001243777
NM_014679
CEP57


centrosomal protein 57kDa


chr19_+_41770273 12.285 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_200322699 12.135 NM_001172509
SATB2
SATB homeobox 2
chr19_+_14640403 12.055 TECR
trans-2,3-enoyl-CoA reductase
chr20_-_45976626 11.874 ZMYND8
zinc finger, MYND-type containing 8
chr3_+_179280746 11.816 ACTL6A
actin-like 6A
chr14_+_23938883 11.722 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr6_+_26104103 11.716 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chr8_+_107738239 11.493 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_-_148804122 11.413 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr14_-_54908035 11.305 NM_005776
CNIH
cornichon homolog (Drosophila)
chr7_-_148725764 11.294 NM_004911
PDIA4
protein disulfide isomerase family A, member 4
chr5_+_43602738 11.278 NM_012343
NNT
nicotinamide nucleotide transhydrogenase
chr20_+_30326903 11.249 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr19_+_14640363 10.494 NM_138501
TECR
trans-2,3-enoyl-CoA reductase
chr5_+_151151514 10.464 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr1_-_149399159 10.288 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr1_+_151227188 10.282 NM_002810
PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr3_+_179280686 10.282 NM_004301
NM_177989
NM_178042
ACTL6A


actin-like 6A


chr1_-_3713048 10.212 NM_020710
LRRC47
leucine rich repeat containing 47
chr12_-_121790165 10.201 ANAPC5
anaphase promoting complex subunit 5
chr5_+_43603216 9.825 NM_182977
NNT
nicotinamide nucleotide transhydrogenase
chr7_-_140179133 9.776 MKRN1
makorin ring finger protein 1
chr22_-_43411129 9.721 PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr22_-_43411156 9.652 NM_001184970
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr7_-_148725731 9.363 PDIA4
protein disulfide isomerase family A, member 4
chr1_+_35851101 9.338 ZMYM4
zinc finger, MYM-type 4
chr12_+_28410132 9.328 NM_018318
CCDC91
coiled-coil domain containing 91
chr11_+_67798077 9.251 NM_002496
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr5_+_43603312 9.209 NNT
nicotinamide nucleotide transhydrogenase
chr8_+_98788014 9.165 LAPTM4B
lysosomal protein transmembrane 4 beta
chr14_-_55658205 8.970 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr3_+_136581007 8.832 NM_006153
NCK1
NCK adaptor protein 1
chr1_+_145663156 8.625 RNF115
ring finger protein 115
chr1_+_155278538 8.569 NM_001135822
NM_001242824
NM_001242825
NM_002004
FDPS



farnesyl diphosphate synthase



chrX_-_10645726 8.527 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr19_+_54619114 8.351 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr2_-_219134846 8.332 AAMP
angio-associated, migratory cell protein
chr1_+_149858466 8.319 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr1_+_32645322 8.311 NM_175852
TXLNA
taxilin alpha
chr2_+_171784947 8.248 NM_001201428
NM_015530
GORASP2

golgi reassembly stacking protein 2, 55kDa

chr1_-_241683060 8.012 NM_000143
FH
fumarate hydratase
chrX_-_23761396 7.960 NM_001033583
NM_001037171
ACOT9

acyl-CoA thioesterase 9

chr12_-_121790141 7.936 ANAPC5
anaphase promoting complex subunit 5
chr19_+_41770285 7.872 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr7_-_7758237 7.867 NM_002947
RPA3
replication protein A3, 14kDa
chr19_-_39881631 7.740 NM_019088
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr3_+_171757432 7.727 FNDC3B
fibronectin type III domain containing 3B
chr12_-_56679729 7.667 CS
citrate synthase
chr1_-_42801529 7.662 NM_001198850
FOXJ3
forkhead box J3
chrX_+_70503496 7.653 NONO
non-POU domain containing, octamer-binding
chr1_-_241683011 7.632 FH
fumarate hydratase
chr5_+_151151462 7.575 NM_005754
NM_198395
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr12_+_21168629 7.529 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr16_-_58663734 7.499 CNOT1
CCR4-NOT transcription complex, subunit 1
chr3_+_136581074 7.474 NCK1
NCK adaptor protein 1
chr1_-_156308047 7.468 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr2_+_12856813 7.443 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr12_-_121790240 7.438 NM_016237
ANAPC5
anaphase promoting complex subunit 5
chr19_+_2269515 7.429 NM_004152
OAZ1
SPPL2B
ornithine decarboxylase antizyme 1
signal peptide peptidase-like 2B
chr9_+_91926109 7.423 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr11_+_95523809 7.417 CEP57
centrosomal protein 57kDa
chr19_+_49375679 7.416 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr1_+_236557643 7.385 NM_145861
EDARADD
EDAR-associated death domain
chr16_+_69220940 7.337 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr4_-_48782281 7.328 NM_015030
FRYL
FRY-like
chr5_+_179132676 7.289 CANX
calnexin
chr1_+_214776494 7.275 NM_016343
CENPF
centromere protein F, 350/400kDa (mitosin)
chr3_+_136649316 7.262 NM_001190796
NCK1
NCK adaptor protein 1
chr19_-_14247400 7.244 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr19_+_49375677 7.230 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr6_-_42713822 7.201 TBCC
tubulin folding cofactor C
chr12_-_120638912 7.201 NM_001002
NM_053275
RPLP0

ribosomal protein, large, P0

chr3_-_160283166 7.184 KPNA4
karyopherin alpha 4 (importin alpha 3)
chr19_-_14640048 7.181 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_219134865 7.155 NM_001087
AAMP
angio-associated, migratory cell protein
chr17_-_29151724 7.150 NM_015986
CRLF3
cytokine receptor-like factor 3
chr17_-_29151638 7.143 CRLF3
cytokine receptor-like factor 3
chr19_+_2269526 7.106 OAZ1
ornithine decarboxylase antizyme 1
chr9_+_79968344 7.029 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr12_-_14956408 7.006 WBP11
WW domain binding protein 11
chr5_+_151151516 6.976 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr4_+_83956238 6.956 NM_016129
COPS4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr2_-_219134795 6.905 AAMP
angio-associated, migratory cell protein
chr11_-_57195052 6.904 NM_017611
SLC43A3
solute carrier family 43, member 3
chr11_+_69467210 6.853 CCND1
cyclin D1
chr19_+_49375638 6.845 NM_014330
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_-_61765394 6.826 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chrX_+_70503469 6.725 NONO
non-POU domain containing, octamer-binding
chr6_+_160183510 6.682 ACAT2
acetyl-CoA acetyltransferase 2
chrX_-_107334749 6.666 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr2_+_191745547 6.657 GLS
glutaminase
chr14_-_75530716 6.655 NM_001107
NM_203488
ACYP1

acylphosphatase 1, erythrocyte (common) type

chr17_+_73663398 6.650 NM_013260
SAP30BP
SAP30 binding protein
chr4_-_72649734 6.583 NM_000583
GC
group-specific component (vitamin D binding protein)
chrX_+_47004657 6.553 RBM10
RNA binding motif protein 10
chr19_-_18433847 6.539 LSM4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_+_70503512 6.404 NONO
non-POU domain containing, octamer-binding
chr1_-_156307971 6.395 CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr19_+_41770057 6.317 NM_007040
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chrX_+_47004663 6.295 RBM10
RNA binding motif protein 10
chr9_+_131447364 6.260 NM_001248000
SET
SET nuclear oncogene
chr2_-_174829951 6.232 SP3
Sp3 transcription factor
chrX_+_47004676 6.210 RBM10
RNA binding motif protein 10
chrX_+_47004693 6.200 RBM10
RNA binding motif protein 10
chr6_-_42713837 6.173 NM_003192
TBCC
tubulin folding cofactor C
chr18_+_77866914 6.173 NM_014913
ADNP2
ADNP homeobox 2
chr19_+_2269529 6.117 OAZ1
ornithine decarboxylase antizyme 1
chr17_-_46622274 6.032 NM_002145
HOXB2
homeobox B2
chrX_+_47004665 6.029 RBM10
RNA binding motif protein 10
chr15_+_59397276 6.027 NM_004701
CCNB2
cyclin B2
chrX_+_47004633 5.940 RBM10
RNA binding motif protein 10
chr20_+_44441671 5.912 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr12_-_14956367 5.904 NM_016312
WBP11
WW domain binding protein 11
chr12_-_120315074 5.896 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr3_-_160283071 5.880 KPNA4
karyopherin alpha 4 (importin alpha 3)
chrX_+_47004609 5.818 NM_001204466
NM_001204467
NM_001204468
NM_005676
NM_152856
RBM10




RNA binding motif protein 10




chr3_-_121553907 5.784 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chrX_+_47004670 5.782 RBM10
RNA binding motif protein 10
chr4_-_84035888 5.768 PLAC8
placenta-specific 8
chr1_+_110881944 5.696 NM_001201545
NM_022768
RBM15

RNA binding motif protein 15

chr9_+_36190885 5.689 CLTA
clathrin, light chain A
chr2_-_61765367 5.675 XPO1
exportin 1 (CRM1 homolog, yeast)
chr19_-_39881503 5.667 PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr17_-_1588098 5.635 PRPF8
PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
chr17_-_79818318 5.618 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr22_-_30642683 5.611 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr2_-_61765345 5.610 XPO1
exportin 1 (CRM1 homolog, yeast)
chr3_-_121553836 5.596 IQCB1
IQ motif containing B1
chr22_-_17640153 5.592 CECR5
cat eye syndrome chromosome region, candidate 5
chr19_+_54704659 5.506 NM_001013
RPS9
ribosomal protein S9
chr12_-_54653317 5.501 NM_001127322
CBX5
chromobox homolog 5
chr3_-_160283311 5.475 KPNA4
karyopherin alpha 4 (importin alpha 3)
chr18_-_47018842 5.424 NM_001199356
NM_000985
NM_001035006
NM_001199340
NM_001199345
RPL17-C18ORF32
RPL17



RPL17-C18orf32 readthrough
ribosomal protein L17



chr10_+_70660955 5.382 NM_024045
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr14_+_93673583 5.353 UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr14_+_96001297 5.326 NM_016417
GLRX5
glutaredoxin 5
chr20_+_18488525 5.306 SEC23B
Sec23 homolog B (S. cerevisiae)
chrX_+_70503534 5.260 NONO
non-POU domain containing, octamer-binding

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.15 2.50e-12 GO:0034621 cellular macromolecular complex subunit organization
4.76 3.54e-12 GO:0034622 cellular macromolecular complex assembly
2.36 3.71e-10 GO:0006996 organelle organization
1.99 3.83e-10 GO:0071842 cellular component organization at cellular level
8.17 4.51e-10 GO:0065004 protein-DNA complex assembly
1.96 6.74e-10 GO:0071841 cellular component organization or biogenesis at cellular level
7.73 1.33e-09 GO:0071824 protein-DNA complex subunit organization
1.78 4.00e-09 GO:0071840 cellular component organization or biogenesis
1.78 1.03e-08 GO:0016043 cellular component organization
6.42 4.77e-08 GO:0006333 chromatin assembly or disassembly
2.75 2.31e-07 GO:0043933 macromolecular complex subunit organization
3.11 2.49e-07 GO:0051276 chromosome organization
7.53 3.91e-07 GO:0006334 nucleosome assembly
2.82 6.34e-07 GO:0071844 cellular component assembly at cellular level
7.14 8.85e-07 GO:0031497 chromatin assembly
2.87 9.59e-07 GO:0065003 macromolecular complex assembly
6.79 1.91e-06 GO:0034728 nucleosome organization
2.79 5.62e-06 GO:0022403 cell cycle phase
5.80 7.13e-06 GO:0006323 DNA packaging
3.62 1.07e-05 GO:0010564 regulation of cell cycle process
2.20 1.17e-05 GO:0051641 cellular localization
5.27 1.19e-05 GO:0071103 DNA conformation change
2.24 1.69e-05 GO:0044085 cellular component biogenesis
1.21 1.72e-05 GO:0009987 cellular process
3.26 1.80e-05 GO:0000279 M phase
2.88 2.48e-05 GO:0000278 mitotic cell cycle
4.29 2.80e-05 GO:0071156 regulation of cell cycle arrest
2.49 6.08e-05 GO:0022402 cell cycle process
4.25 7.26e-05 GO:0000075 cell cycle checkpoint
2.21 9.72e-05 GO:0051649 establishment of localization in cell
4.75 1.45e-04 GO:0043623 cellular protein complex assembly
2.19 3.15e-04 GO:0022607 cellular component assembly
7.22 3.90e-04 GO:0010948 negative regulation of cell cycle process
2.16 4.99e-04 GO:0008104 protein localization
2.17 7.99e-04 GO:0007049 cell cycle
1.45 1.02e-03 GO:0044260 cellular macromolecule metabolic process
2.26 1.15e-03 GO:0045184 establishment of protein localization
2.25 1.88e-03 GO:0015031 protein transport
3.33 1.99e-03 GO:0000280 nuclear division
3.33 1.99e-03 GO:0007067 mitosis
3.43 2.33e-03 GO:0007346 regulation of mitotic cell cycle
1.94 2.98e-03 GO:0033036 macromolecule localization
3.24 3.16e-03 GO:0000087 M phase of mitotic cell cycle
3.24 3.16e-03 GO:0051329 interphase of mitotic cell cycle
2.73 3.26e-03 GO:0006325 chromatin organization
3.23 3.35e-03 GO:0048285 organelle fission
2.45 3.92e-03 GO:0051726 regulation of cell cycle
3.18 4.18e-03 GO:0051325 interphase
2.25 4.47e-03 GO:0046907 intracellular transport
1.32 6.99e-03 GO:0044237 cellular metabolic process
2.92 1.00e-02 GO:0051301 cell division
9.19 1.13e-02 GO:0034976 response to endoplasmic reticulum stress
3.39 1.58e-02 GO:0051129 negative regulation of cellular component organization
2.75 1.58e-02 GO:0006886 intracellular protein transport
2.50 1.68e-02 GO:0034613 cellular protein localization
2.48 1.88e-02 GO:0070727 cellular macromolecule localization
4.17 1.95e-02 GO:0006310 DNA recombination
1.35 2.55e-02 GO:0043170 macromolecule metabolic process
4.33 2.85e-02 GO:0010639 negative regulation of organelle organization
2.87 3.28e-02 GO:0033043 regulation of organelle organization
1.60 3.47e-02 GO:0090304 nucleic acid metabolic process
4.19 3.96e-02 GO:0007093 mitotic cell cycle checkpoint
6.42 4.13e-02 GO:0045732 positive regulation of protein catabolic process
7.58 4.29e-02 GO:0030071 regulation of mitotic metaphase/anaphase transition

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.39 3.48e-17 GO:0043229 intracellular organelle
1.39 4.86e-17 GO:0043226 organelle
1.30 1.94e-16 GO:0044424 intracellular part
1.42 2.52e-15 GO:0043231 intracellular membrane-bounded organelle
1.42 3.02e-15 GO:0043227 membrane-bounded organelle
1.28 5.77e-15 GO:0005622 intracellular
1.64 2.99e-14 GO:0044446 intracellular organelle part
1.63 6.64e-14 GO:0044422 organelle part
1.86 4.50e-09 GO:0043228 non-membrane-bounded organelle
1.86 4.50e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.35 5.04e-09 GO:0005737 cytoplasm
3.31 7.07e-09 GO:0005694 chromosome
3.55 9.98e-09 GO:0044427 chromosomal part
1.96 1.15e-08 GO:0070013 intracellular organelle lumen
1.49 2.88e-08 GO:0005634 nucleus
1.92 3.44e-08 GO:0043233 organelle lumen
1.68 5.94e-08 GO:0032991 macromolecular complex
1.89 8.34e-08 GO:0031974 membrane-enclosed lumen
1.89 5.32e-07 GO:0044428 nuclear part
4.33 9.30e-07 GO:0000785 chromatin
6.84 1.09e-06 GO:0032993 protein-DNA complex
8.66 2.48e-06 GO:0000786 nucleosome
1.89 1.04e-05 GO:0031981 nuclear lumen
1.37 3.56e-05 GO:0044444 cytoplasmic part
1.98 1.56e-04 GO:0005654 nucleoplasm
1.64 2.66e-03 GO:0005829 cytosol
1.07 3.59e-03 GO:0044464 cell part
1.07 3.64e-03 GO:0005623 cell
3.63 4.46e-03 GO:0005819 spindle
5.91 4.98e-03 GO:0000922 spindle pole
2.95 6.80e-03 GO:0005874 microtubule
7.77 6.88e-03 GO:0005876 spindle microtubule
12.03 1.10e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.30 1.78e-02 GO:0030529 ribonucleoprotein complex
1.45 2.08e-02 GO:0043234 protein complex
1.83 2.23e-02 GO:0005783 endoplasmic reticulum
3.10 2.82e-02 GO:0000228 nuclear chromosome
2.05 4.30e-02 GO:0015630 microtubule cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.34 2.97e-06 GO:0005515 protein binding
8.36 1.65e-05 GO:0003697 single-stranded DNA binding
1.15 1.08e-03 GO:0005488 binding
2.06 6.78e-03 GO:0003723 RNA binding
3.51 7.06e-03 GO:0043566 structure-specific DNA binding
1.44 9.33e-03 GO:0003676 nucleic acid binding