Motif ID: POU1F1.p2

Z-value: 1.979


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_873256110.656.4e-28Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_93399531 49.766


chr12_-_91573264 45.112 NM_133503
 DCN
decorin
chr6_-_52628272 34.139 NM_000846
 GSTA2
glutathione S-transferase alpha 2
chr12_-_45307710 31.768 NM_001145110
 NELL2
NEL-like 2 (chicken)
chr4_+_74270832 30.682 ALB
albumin
chr14_-_107013474 29.248 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_196857143 27.912 NM_001201550
NM_001201551
NM_006684
 CFHR4


complement factor H-related 4


chr4_+_106631966 27.707 NM_001031720
 GSTCD
glutathione S-transferase, C-terminal domain containing
chr6_-_33041266 27.577 NM_033554
 HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr7_-_64023444 27.345


chr1_+_196743929 25.784 NM_001166624
NM_021023
 CFHR3

complement factor H-related 3

chr5_-_41213513 25.269 NM_000065
 C6
complement component 6
chr12_+_21679190 25.163 NM_030572
 C12orf39
chromosome 12 open reading frame 39
chr1_-_163172863 24.723 NM_003617
 RGS5
regulator of G-protein signaling 5
chr1_-_161279724 23.629 NM_000530
 MPZ
myelin protein zero
chr8_-_86253863 23.282 NM_001164830
 CA1
carbonic anhydrase I
chr12_-_87232635 22.954 NM_013244
 MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_+_71337833 22.892 NM_152291
 MUC7
mucin 7, secreted
chr4_+_71337674 22.428 NM_001145007
 MUC7
mucin 7, secreted
chr16_-_5116030 22.050 NM_001098514
NM_152459
 C16orf89

chromosome 16 open reading frame 89


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
13.52 5.71e-05 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
11.97 4.94e-02 GO:0010885 regulation of cholesterol storage
10.77 1.56e-02 GO:0015721 bile acid and bile salt transport
8.62 7.90e-04 GO:0060338 regulation of type I interferon-mediated signaling pathway
6.99 5.53e-03 GO:0008206 bile acid metabolic process
6.57 3.18e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
6.27 4.72e-04 GO:0019882 antigen processing and presentation
6.16 1.70e-02 GO:0006956 complement activation
5.75 3.69e-03 GO:0016064 immunoglobulin mediated immune response
5.65 1.55e-03 GO:0072376 protein activation cascade
5.64 4.45e-03 GO:0019724 B cell mediated immunity
5.05 2.14e-03 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
5.00 6.09e-03 GO:0002449 lymphocyte mediated immunity
4.91 2.94e-03 GO:0002250 adaptive immune response
4.32 5.06e-05 GO:0006805 xenobiotic metabolic process
4.32 5.06e-05 GO:0071466 cellular response to xenobiotic stimulus
4.31 2.94e-02 GO:0006959 humoral immune response
4.29 5.76e-05 GO:0009410 response to xenobiotic stimulus
4.10 5.11e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.98 1.55e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
16.41 1.21e-06 GO:0042613 MHC class II protein complex
8.98 1.83e-05 GO:0042611 MHC protein complex
2.62 5.55e-11 GO:0005615 extracellular space
2.32 5.48e-10 GO:0044421 extracellular region part
2.16 1.16e-09 GO:0005887 integral to plasma membrane
2.14 1.27e-09 GO:0031226 intrinsic to plasma membrane
1.97 1.38e-12 GO:0005576 extracellular region
1.82 7.28e-03 GO:0005626 insoluble fraction
1.78 9.25e-09 GO:0044459 plasma membrane part
1.77 2.58e-02 GO:0005624 membrane fraction
1.41 9.07e-06 GO:0071944 cell periphery
1.40 2.29e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
21.54 1.87e-05 GO:0005132 interferon-alpha/beta receptor binding
15.96 2.32e-03 GO:0004022 alcohol dehydrogenase (NAD) activity
14.36 3.75e-02 GO:0032395 MHC class II receptor activity
11.05 2.11e-02 GO:0004993 serotonin receptor activity
7.18 1.53e-02 GO:0016229 steroid dehydrogenase activity
5.75 2.41e-02 GO:0003823 antigen binding
3.83 6.65e-06 GO:0005126 cytokine receptor binding
3.26 4.56e-04 GO:0005125 cytokine activity
1.60 3.72e-02 GO:0004888 transmembrane receptor activity
1.59 3.67e-03 GO:0004872 receptor activity
1.49 9.95e-03 GO:0004871 signal transducer activity
1.49 9.95e-03 GO:0060089 molecular transducer activity