Motif ID: POU2F1..3.p2

Z-value: 3.082


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F2chr19_-_426365590.584.2e-21Click!
POU2F3chr11_+_1201073480.321.1e-06Click!
POU2F1chr1_+_1671899480.244.0e-04Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_107013474 246.392 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106926393 146.570 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22758538 130.635


chr22_+_22735134 125.974 CYAT1
immunoglobulin lambda light chain-like
chr14_-_106725620 112.133 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106610338 104.797 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106573348 103.142 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_106994001 102.075 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr22_+_22786283 99.895


chr22_+_22735207 99.008 IGLJ3
immunoglobulin lambda joining 3
chr14_-_107170400 90.484 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr22_+_23165273 88.446


chr22_+_22712091 83.661 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr22_+_23040394 82.422 IGL@
immunoglobulin lambda locus
chr2_-_89619820 72.384 IGKC
immunoglobulin kappa constant
chr14_-_106518424 65.169 IGH@
IGHA1
IGHG1
IGHG2
IGHM
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr14_-_107113943 64.818 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107099379 62.710 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_-_89513056 62.442 IGKC
immunoglobulin kappa constant
chr14_-_106967528 61.743 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
12.49 4.53e-02 GO:0050853 B cell receptor signaling pathway
11.35 1.52e-14 GO:0006334 nucleosome assembly
10.76 5.17e-14 GO:0031497 chromatin assembly
10.23 1.63e-13 GO:0034728 nucleosome organization
9.85 3.89e-13 GO:0065004 protein-DNA complex assembly
9.32 1.34e-12 GO:0071824 protein-DNA complex subunit organization
8.22 2.11e-11 GO:0006323 DNA packaging
8.08 7.67e-12 GO:0006333 chromatin assembly or disassembly
7.91 2.97e-02 GO:0030183 B cell differentiation
7.72 3.48e-02 GO:0050909 sensory perception of taste
7.05 5.51e-10 GO:0071103 DNA conformation change
6.89 6.50e-03 GO:0060333 interferon-gamma-mediated signaling pathway
6.59 2.91e-03 GO:0042113 B cell activation
6.53 9.99e-04 GO:0006959 humoral immune response
6.28 1.42e-02 GO:0071346 cellular response to interferon-gamma
5.17 1.03e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
5.10 2.99e-02 GO:0050851 antigen receptor-mediated signaling pathway
4.97 1.50e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
4.13 1.95e-03 GO:0019221 cytokine-mediated signaling pathway
4.01 6.53e-04 GO:0002253 activation of immune response

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
17.40 6.48e-20 GO:0000786 nucleosome
10.99 4.88e-15 GO:0032993 protein-DNA complex
5.57 6.18e-11 GO:0000785 chromatin
3.03 2.92e-05 GO:0044427 chromosomal part
2.54 9.70e-04 GO:0005694 chromosome

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
15.81 2.63e-03 GO:0008527 taste receptor activity
13.05 9.69e-08 GO:0003823 antigen binding