Motif ID: POU3F1..4.p2

Z-value: 0.849


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU3F3chr2_+_1054717450.384.3e-09Click!
POU3F4chrX_+_827632680.363.0e-08Click!
POU3F1chr1_-_385124460.291.1e-05Click!
POU3F2chr6_+_992825970.243.1e-04Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_150399980 19.537 NM_002084
 GPX3
glutathione peroxidase 3 (plasma)
chr5_+_40909617 17.330 C7
complement component 7
chr5_+_40909558 16.172 NM_000587
 C7
complement component 7
chr2_+_189839113 15.427 COL3A1
collagen, type III, alpha 1
chr2_+_189839132 13.964 COL3A1
collagen, type III, alpha 1
chr6_+_121756744 12.725 NM_000165
 GJA1
gap junction protein, alpha 1, 43kDa
chr12_-_91505215 11.909 LUM
lumican
chr4_+_74270832 11.857 ALB
albumin
chr4_+_88896868 11.697 SPP1
secreted phosphoprotein 1
chr2_+_189839078 10.990 NM_000090
 COL3A1
collagen, type III, alpha 1
chr6_-_46889620 10.948 NM_001098518
 GPR116
G protein-coupled receptor 116
chr4_+_88896838 10.228 SPP1
secreted phosphoprotein 1
chr3_-_123339178 10.149 MYLK
myosin light chain kinase
chr12_-_16759939 9.340 NM_001243613
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_16759733 8.949 NM_001243610
 LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_65384078 8.165 NM_001130860
NM_014799
 HEPH

hephaestin

chr4_-_88450601 7.651 NM_001128310
NM_004684
 SPARCL1

SPARC-like 1 (hevin)

chr4_+_74269971 7.288 NM_000477
 ALB
albumin
chr12_-_9268513 6.867 A2M
alpha-2-macroglobulin
chr8_+_39771327 6.445 NM_002164
 IDO1
indoleamine 2,3-dioxygenase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
15.64 1.26e-02 GO:0006067 ethanol metabolic process
15.64 1.26e-02 GO:0006069 ethanol oxidation
15.64 1.26e-02 GO:0034308 primary alcohol metabolic process
7.86 8.72e-03 GO:0002455 humoral immune response mediated by circulating immunoglobulin
7.77 3.72e-02 GO:0006958 complement activation, classical pathway
7.44 1.36e-02 GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
6.77 2.31e-04 GO:0072376 protein activation cascade
6.55 3.66e-02 GO:0006956 complement activation
5.59 7.30e-04 GO:0006959 humoral immune response
4.14 2.41e-03 GO:0006805 xenobiotic metabolic process
4.14 2.41e-03 GO:0071466 cellular response to xenobiotic stimulus
4.11 2.67e-03 GO:0009410 response to xenobiotic stimulus
2.71 3.53e-02 GO:0016337 cell-cell adhesion
2.35 5.88e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
2.06 1.43e-02 GO:0007155 cell adhesion
2.06 1.43e-02 GO:0022610 biological adhesion
1.59 4.13e-03 GO:0042221 response to chemical stimulus
1.43 5.58e-04 GO:0051716 cellular response to stimulus
1.41 1.14e-02 GO:0023052 signaling
1.41 2.51e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
19.66 5.55e-03 GO:0005579 membrane attack complex
2.63 4.65e-09 GO:0005615 extracellular space
2.24 3.07e-07 GO:0044421 extracellular region part
2.00 1.33e-03 GO:0005626 insoluble fraction
1.94 6.36e-03 GO:0005624 membrane fraction
1.89 5.72e-04 GO:0000267 cell fraction
1.81 9.67e-04 GO:0005887 integral to plasma membrane
1.79 2.24e-07 GO:0044459 plasma membrane part
1.78 1.75e-03 GO:0031226 intrinsic to plasma membrane
1.71 1.76e-05 GO:0005576 extracellular region
1.50 5.45e-07 GO:0071944 cell periphery
1.48 3.49e-06 GO:0005886 plasma membrane
1.23 2.08e-02 GO:0044425 membrane part
1.22 2.89e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
19.11 8.92e-04 GO:0004022 alcohol dehydrogenase (NAD) activity
10.75 2.61e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
6.26 1.29e-02 GO:0043498 cell surface binding
4.30 1.80e-02 GO:0008081 phosphoric diester hydrolase activity
3.28 3.75e-02 GO:0005539 glycosaminoglycan binding
3.25 2.38e-02 GO:0001871 pattern binding
3.25 2.38e-02 GO:0030247 polysaccharide binding
2.08 6.15e-03 GO:0005509 calcium ion binding