Motif ID: POU5F1.p2

Z-value: 2.771


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_311381800.351.3e-07Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_176734181 68.085 NM_201591
 GPM6A
glycoprotein M6A
chr12_-_16757944 65.734 LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_-_106733392 62.463 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_-_37024664 62.187 NM_001039459
 ELMO1
engulfment and cell motility 1
chrX_-_13835012 56.758 GPM6B
glycoprotein M6B
chr2_-_89442551 53.849 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr18_-_53089722 53.831 NM_001243233
 TCF4
transcription factor 4
chr22_+_23213671 52.406 IGLV4-3
immunoglobulin lambda variable 4-3
chr22_+_22697538 52.237


chr22_+_22735134 50.472 CYAT1
immunoglobulin lambda light chain-like
chrX_-_13835313 48.484 NM_001001995
NM_001001996
NM_005278
 GPM6B


glycoprotein M6B


chr22_+_22758538 48.224


chr6_-_108145507 46.920 NM_198081
 SCML4
sex comb on midleg-like 4 (Drosophila)
chr2_+_89185055 46.123


chrX_-_13835213 44.354 GPM6B
glycoprotein M6B
chrX_-_13835187 43.308 GPM6B
glycoprotein M6B
chr16_+_23847321 42.987 PRKCB
protein kinase C, beta
chr14_-_107066061 42.672 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_106960268 41.169 NM_004089
 TSC22D3
TSC22 domain family, member 3
chr14_-_107179043 40.936 IGHA1
immunoglobulin heavy constant alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 156 entries
enrichment   p-value GO term description
7.77 1.77e-02 GO:0021602 cranial nerve morphogenesis
4.50 4.74e-06 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
3.88 1.88e-02 GO:0048663 neuron fate commitment
3.29 2.44e-02 GO:0032526 response to retinoic acid
3.24 2.86e-03 GO:0048706 embryonic skeletal system development
3.05 1.45e-02 GO:0042063 gliogenesis
3.02 3.54e-03 GO:0050851 antigen receptor-mediated signaling pathway
3.01 7.04e-06 GO:0045165 cell fate commitment
2.93 5.32e-06 GO:0009952 anterior/posterior pattern formation
2.91 2.65e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.90 4.53e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.89 1.58e-04 GO:0007156 homophilic cell adhesion
2.69 3.21e-03 GO:0001503 ossification
2.66 1.31e-04 GO:0030900 forebrain development
2.54 8.49e-08 GO:0016337 cell-cell adhesion
2.54 3.31e-03 GO:0048562 embryonic organ morphogenesis
2.53 7.98e-03 GO:0001655 urogenital system development
2.47 3.18e-05 GO:0003002 regionalization
2.34 4.97e-04 GO:0048568 embryonic organ development
2.32 4.66e-06 GO:0051093 negative regulation of developmental process

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.98 6.09e-05 GO:0043005 neuron projection
1.96 2.09e-02 GO:0000785 chromatin
1.86 9.87e-04 GO:0045202 synapse
1.81 5.77e-03 GO:0009986 cell surface
1.71 1.02e-09 GO:0031226 intrinsic to plasma membrane
1.71 1.59e-09 GO:0005887 integral to plasma membrane
1.61 5.44e-14 GO:0044459 plasma membrane part
1.56 3.42e-03 GO:0005615 extracellular space
1.49 1.15e-02 GO:0042995 cell projection
1.46 6.63e-03 GO:0044421 extracellular region part
1.37 8.05e-12 GO:0005886 plasma membrane
1.36 3.53e-11 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
10.46 1.28e-03 GO:0003708 retinoic acid receptor activity
4.79 7.12e-07 GO:0003707 steroid hormone receptor activity
4.75 3.28e-07 GO:0004879 ligand-dependent nuclear receptor activity
4.58 1.75e-04 GO:0003823 antigen binding
3.33 1.60e-02 GO:0042562 hormone binding
2.39 5.59e-18 GO:0043565 sequence-specific DNA binding
2.18 4.81e-03 GO:0000975 regulatory region DNA binding
2.18 4.81e-03 GO:0001067 regulatory region nucleic acid binding
2.18 4.81e-03 GO:0044212 transcription regulatory region DNA binding
2.15 4.68e-19 GO:0001071 nucleic acid binding transcription factor activity
2.15 4.68e-19 GO:0003700 sequence-specific DNA binding transcription factor activity
2.14 1.23e-02 GO:0010843 promoter binding
1.90 7.62e-03 GO:0016563 transcription activator activity
1.89 4.66e-07 GO:0005509 calcium ion binding
1.87 2.85e-11 GO:0030528 transcription regulator activity
1.70 3.18e-02 GO:0008289 lipid binding
1.46 2.34e-08 GO:0003677 DNA binding
1.43 3.98e-02 GO:0005102 receptor binding
1.39 8.21e-05 GO:0004871 signal transducer activity
1.39 8.21e-05 GO:0060089 molecular transducer activity