Motif ID: POU5F1.p2

Z-value: 2.771


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_311381800.351.3e-07Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_176734181 68.085 NM_201591
GPM6A
glycoprotein M6A
chr12_-_16757944 65.734 LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_-_106733392 62.463 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_-_37024664 62.187 NM_001039459
ELMO1
engulfment and cell motility 1
chrX_-_13835012 56.758 GPM6B
glycoprotein M6B
chr2_-_89442551 53.849 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr18_-_53089722 53.831 NM_001243233
TCF4
transcription factor 4
chr22_+_23213671 52.406 IGLV4-3
immunoglobulin lambda variable 4-3
chr22_+_22697538 52.237


chr22_+_22735134 50.472 CYAT1
immunoglobulin lambda light chain-like
chrX_-_13835313 48.484 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr22_+_22758538 48.224


chr6_-_108145507 46.920 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr2_+_89185055 46.123


chrX_-_13835213 44.354 GPM6B
glycoprotein M6B
chrX_-_13835187 43.308 GPM6B
glycoprotein M6B
chr16_+_23847321 42.987 PRKCB
protein kinase C, beta
chr14_-_107066061 42.672 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_106960268 41.169 NM_004089
TSC22D3
TSC22 domain family, member 3
chr14_-_107179043 40.936 IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_22735207 40.483 IGLJ3
immunoglobulin lambda joining 3
chr12_-_91576579 39.857 DCN
decorin
chr18_-_52988916 39.147 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr12_-_16758312 38.372 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_-_106960028 38.271 TSC22D3
TSC22 domain family, member 3
chr22_+_23040394 37.618 IGL@
immunoglobulin lambda locus
chr12_-_16760935 36.968 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr17_+_7554415 36.937 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr16_+_23847271 36.442 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr22_+_22712091 36.390 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr14_-_107013474 36.121 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_23847359 35.949 PRKCB
protein kinase C, beta
chr22_+_23010757 35.941


chr17_+_7554239 35.513 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr22_+_23165273 35.343


chr10_+_11207053 34.985 CELF2
CUGBP, Elav-like family member 2
chr22_+_22786283 34.972


chr22_+_23063107 34.928 IGLJ3
immunoglobulin lambda joining 3
chr16_-_4322695 34.069 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr4_-_176733901 33.915 GPM6A
glycoprotein M6A
chr7_-_130080823 33.749 NM_018718
CEP41
centrosomal protein 41kDa
chr4_-_153303663 33.453 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr1_-_153363544 33.446 NM_002964
S100A8
S100 calcium binding protein A8
chr4_-_176733413 33.349 GPM6A
glycoprotein M6A
chr1_+_228645807 32.110 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr1_-_31230673 31.391 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr14_-_107131217 31.363 IGHA1
immunoglobulin heavy constant alpha 1
chr12_-_16759733 31.122 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_175712276 30.929 NM_001206602
CHN1
chimerin (chimaerin) 1
chr2_+_90077732 30.625


chr16_-_4323000 30.466 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr14_-_106405633 30.029 IGHM
immunoglobulin heavy constant mu
chr4_+_158141735 29.904 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr19_-_18314731 28.843 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr19_-_39108534 28.636 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr22_+_22676814 28.561


chr14_-_107170400 28.463 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr17_-_8063946 28.427 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr12_-_16759939 27.933 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_+_68961912 27.873 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr3_-_18480203 26.649 NM_001131010
SATB1
SATB homeobox 1
chr22_+_23134980 26.534


chr2_-_89513056 25.802 IGKC
immunoglobulin kappa constant
chr14_-_106641585 25.358 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_+_137967088 25.335 NM_014279
NM_006334
OLFM1

olfactomedin 1

chr14_-_106967528 25.303 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr12_-_91576805 25.287 NM_001920
DCN
decorin
chr17_+_7554711 24.956 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr12_-_16759430 24.874 LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_+_20771745 24.850


chr14_-_21271002 24.722 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr19_-_44123732 24.713 ZNF428
zinc finger protein 428
chr20_+_17207680 24.618 PCSK2
proprotein convertase subtilisin/kexin type 2
chr22_+_22735202 24.470


chr7_-_31380507 23.967 NM_022728
NEUROD6
neurogenic differentiation 6
chr8_-_27115897 23.902 NM_030795
STMN4
stathmin-like 4
chr10_+_11206928 23.807 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr20_+_17207669 23.668 PCSK2
proprotein convertase subtilisin/kexin type 2
chr12_-_16759531 23.527 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr22_+_23154240 22.845


chr4_-_71532206 22.823 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr15_+_91769329 22.758 SV2B
synaptic vesicle glycoprotein 2B
chr18_-_53255361 22.452 TCF4
transcription factor 4
chr2_+_90211704 22.359


chr17_-_38256548 22.300 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr9_+_137967401 22.267 OLFM1
olfactomedin 1
chr17_+_38219040 22.222 NM_001190918
NM_003250
NM_199334
THRA


thyroid hormone receptor, alpha


chr11_-_62369097 21.924 MTA2
metastasis associated 1 family, member 2
chr18_-_53255734 21.812 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr1_+_84609941 21.784 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_-_106746056 21.721


chr2_+_17721806 21.537 NM_003385
VSNL1
visinin-like 1
chr4_-_71532341 21.529 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr13_-_30881141 21.486 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr18_-_53257033 21.471 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr1_-_228645517 21.377 NM_033445
HIST3H2A
histone cluster 3, H2a
chr5_-_88179278 21.248 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr2_+_17721983 20.881 VSNL1
visinin-like 1
chr22_+_23029175 20.690 IGLV3-25
immunoglobulin lambda variable 3-25
chr14_-_106494166 20.499 IGHV4-31
IGHA1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
chr2_-_89619820 20.467 IGKC
immunoglobulin kappa constant
chr6_-_32908583 20.422 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr14_-_106610338 20.167 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22550112 20.148


chr1_-_177133950 20.127 NM_004319
NM_207108
ASTN1

astrotactin 1

chr1_-_149858114 19.869 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr14_-_106691698 19.828


chr1_+_155853546 19.605 SYT11
synaptotagmin XI
chr7_-_100183722 19.435 LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_-_154651214 19.326 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr15_+_84115979 19.150 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr1_+_50574601 19.127 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_51611476 18.972 POU6F1
POU class 6 homeobox 1
chr17_-_62009620 18.841 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr8_+_26435339 18.718 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr9_+_137967366 18.675 OLFM1
olfactomedin 1
chr9_-_35732089 18.583 TLN1
talin 1
chr12_+_14518608 18.573 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr3_+_181430075 18.549 SOX2
SRY (sex determining region Y)-box 2
chr12_-_45269340 18.064 NM_001145109
NELL2
NEL-like 2 (chicken)
chr11_-_62369213 18.011 MTA2
metastasis associated 1 family, member 2
chr7_-_126883568 18.004 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr17_-_8815799 17.933 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr2_+_220378891 17.902 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr19_-_1021122 17.882 NM_001033026
NM_033420
C19orf6

chromosome 19 open reading frame 6

chr4_-_153273683 17.844 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr9_-_34691135 17.787 NM_006274
CCL19
chemokine (C-C motif) ligand 19
chr6_-_35656610 17.674 FKBP5
FK506 binding protein 5
chr5_+_36608430 17.350 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_167005641 17.254 NM_001202435
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr16_-_79634610 17.239 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr14_-_107113943 17.110 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107048697 17.035 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_217263195 16.961 NM_001243505
ESRRG
estrogen-related receptor gamma
chr6_-_32557431 16.747 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr1_+_220863627 16.466 NM_024709
C1orf115
chromosome 1 open reading frame 115
chr1_+_104198301 16.206 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr22_+_22764094 16.177


chr10_-_98031154 16.066 NM_001114094
NM_013314
BLNK

B-cell linker

chr1_-_204380903 15.948 NM_032833
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr14_-_106573348 15.947 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr19_-_57336373 15.939 NM_001146186
PEG3
paternally expressed 3
chr3_+_109128836 15.916 NM_001145553
FLJ25363
uncharacterized LOC401082
chr1_-_160681552 15.772 NM_001778
CD48
CD48 molecule
chr1_-_149859465 15.638 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr8_-_102803196 15.595 NCALD
neurocalcin delta
chr7_-_64023444 15.572


chr12_-_6772252 15.547 NM_001127582
NM_001127583
NM_001127584
NM_001127585
NM_001127586
NM_016162
ING4





inhibitor of growth family, member 4





chr14_-_106994001 15.487 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr7_-_37488894 15.229 NM_001206480
ELMO1
engulfment and cell motility 1
chr5_-_39203061 15.056 FYB
FYN binding protein
chr12_-_9268522 14.937 NM_000014
A2M
alpha-2-macroglobulin
chr15_+_74422920 14.760 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_-_76829109 14.711 NM_006682
FGL2
fibrinogen-like 2
chr15_+_25101697 14.682 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr1_+_66458389 14.665 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr13_-_77460432 14.556 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr11_-_62369250 14.480 NM_004739
MTA2
metastasis associated 1 family, member 2
chr6_+_31588444 14.441 NM_004638
NM_080686
PRRC2A

proline-rich coiled-coil 2A

chr14_-_21270537 14.418 NM_198232
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr12_-_9268440 14.330 A2M
alpha-2-macroglobulin
chr1_+_50574589 14.303 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr7_+_65419441 14.276 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr20_-_52687014 14.242 BCAS1
breast carcinoma amplified sequence 1
chr12_+_58003962 14.234 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr12_+_25205488 14.200 LRMP
lymphoid-restricted membrane protein
chr4_-_186733372 14.184 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr14_-_58764805 14.180 FLJ31306
uncharacterized LOC379025
chr2_+_226265601 13.991 NM_020864
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr15_-_22473092 13.977


chr14_-_106539099 13.954 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_107122358 13.925


chr14_-_106926393 13.898 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106478129 13.742 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_107078578 13.682


chr3_+_134514044 13.657 NM_004441
EPHB1
EPH receptor B1
chr17_-_38256905 13.614 NM_021724
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr6_-_35656677 13.602 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr5_-_160279045 13.483 NM_025153
ATP10B
ATPase, class V, type 10B
chr1_-_40157067 13.395 NM_016257
HPCAL4
hippocalcin like 4
chr9_+_125796845 13.280 NM_005294
GPR21
G protein-coupled receptor 21
chr19_-_4723755 13.231 DPP9
dipeptidyl-peptidase 9
chr1_+_192778168 13.190 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr9_-_35618300 13.152 NM_001782
CD72
CD72 molecule
chr1_+_6052357 13.069 NM_001199861
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr14_-_106725620 13.053 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr20_+_17207596 13.033 NM_001201529
NM_002594
PCSK2

proprotein convertase subtilisin/kexin type 2

chr22_+_31742739 13.025 FLJ20464
uncharacterized protein FLJ20464
chr22_-_18923963 12.988 NM_001195226
NM_016335
PRODH

proline dehydrogenase (oxidase) 1

chr12_+_57522247 12.987 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr6_+_37137882 12.917 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr2_+_68592317 12.890 NM_002664
PLEK
pleckstrin
chr5_-_24645084 12.856 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr6_+_31588523 12.759 PRRC2A
proline-rich coiled-coil 2A
chr8_+_19796730 12.734 LPL
lipoprotein lipase
chr15_+_62682682 12.682 TLN2
talin 2
chr14_-_106877689 12.679 IGHV4-31
IGH@
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr5_-_39270708 12.667 NM_001243093
FYB
FYN binding protein
chr2_-_192015706 12.661 STAT4
signal transducer and activator of transcription 4
chr3_+_46395224 12.496 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.64 2.08e-22 GO:0048856 anatomical structure development
1.68 8.49e-22 GO:0048731 system development
1.44 2.44e-21 GO:0032501 multicellular organismal process
1.55 2.64e-21 GO:0032502 developmental process
1.59 3.35e-21 GO:0007275 multicellular organismal development
1.31 2.00e-20 GO:0065007 biological regulation
1.31 1.03e-18 GO:0050789 regulation of biological process
1.32 4.52e-18 GO:0050794 regulation of cellular process
1.50 9.28e-17 GO:0023052 signaling
1.89 1.29e-16 GO:0007399 nervous system development
1.70 3.32e-15 GO:0030154 cell differentiation
1.68 8.11e-15 GO:0048869 cellular developmental process
1.32 6.32e-14 GO:0050896 response to stimulus
1.16 1.58e-13 GO:0009987 cellular process
1.69 1.60e-13 GO:0048513 organ development
1.47 5.43e-13 GO:0007165 signal transduction
2.02 2.20e-12 GO:0022008 neurogenesis
1.59 2.51e-11 GO:0006355 regulation of transcription, DNA-dependent
2.14 3.43e-11 GO:0030182 neuron differentiation
1.54 9.92e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.55 2.13e-10 GO:0051252 regulation of RNA metabolic process
1.49 3.44e-10 GO:0031326 regulation of cellular biosynthetic process
1.51 3.57e-10 GO:0010468 regulation of gene expression
1.62 4.49e-10 GO:0007166 cell surface receptor linked signaling pathway
1.51 4.57e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.49 4.81e-10 GO:0009889 regulation of biosynthetic process
1.87 1.24e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.94 1.25e-09 GO:0048699 generation of neurons
1.74 4.03e-09 GO:0002376 immune system process
1.40 5.92e-09 GO:0060255 regulation of macromolecule metabolic process
1.66 6.28e-09 GO:0009653 anatomical structure morphogenesis
1.57 7.70e-09 GO:0048583 regulation of response to stimulus
1.87 7.83e-09 GO:0050793 regulation of developmental process
1.46 8.17e-09 GO:0048518 positive regulation of biological process
1.35 8.19e-09 GO:0051716 cellular response to stimulus
1.39 9.98e-09 GO:0080090 regulation of primary metabolic process
2.20 1.64e-08 GO:0007417 central nervous system development
2.01 2.05e-08 GO:0045595 regulation of cell differentiation
1.70 2.15e-08 GO:0051239 regulation of multicellular organismal process
1.37 2.61e-08 GO:0031323 regulation of cellular metabolic process
1.84 3.02e-08 GO:0048468 cell development
1.45 3.79e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.09 4.34e-08 GO:0048666 neuron development
1.49 7.37e-08 GO:0042221 response to chemical stimulus
1.98 7.42e-08 GO:0010628 positive regulation of gene expression
2.54 8.49e-08 GO:0016337 cell-cell adhesion
1.84 1.14e-07 GO:0006351 transcription, DNA-dependent
1.91 1.22e-07 GO:0007155 cell adhesion
1.91 1.22e-07 GO:0022610 biological adhesion
1.91 1.57e-07 GO:2000026 regulation of multicellular organismal development
1.34 1.60e-07 GO:0019222 regulation of metabolic process
1.42 1.62e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.81 6.87e-07 GO:0040011 locomotion
1.70 1.74e-06 GO:0010646 regulation of cell communication
1.55 1.78e-06 GO:0023051 regulation of signaling
1.83 4.21e-06 GO:0006955 immune response
2.32 4.66e-06 GO:0051093 negative regulation of developmental process
4.50 4.74e-06 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2.93 5.32e-06 GO:0009952 anterior/posterior pattern formation
2.07 5.38e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.01 7.04e-06 GO:0045165 cell fate commitment
1.69 7.35e-06 GO:0007154 cell communication
1.91 1.18e-05 GO:0009887 organ morphogenesis
1.84 1.21e-05 GO:0002682 regulation of immune system process
1.41 1.26e-05 GO:0048522 positive regulation of cellular process
1.89 1.46e-05 GO:0045893 positive regulation of transcription, DNA-dependent
2.08 1.50e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
2.19 1.62e-05 GO:0007420 brain development
1.69 1.80e-05 GO:0032774 RNA biosynthetic process
2.09 1.98e-05 GO:0007409 axonogenesis
1.76 2.10e-05 GO:0048584 positive regulation of response to stimulus
2.47 3.18e-05 GO:0003002 regionalization
1.96 5.75e-05 GO:0001775 cell activation
2.01 7.24e-05 GO:0048812 neuron projection morphogenesis
1.56 8.57e-05 GO:0009893 positive regulation of metabolic process
1.82 9.90e-05 GO:0030030 cell projection organization
1.94 1.07e-04 GO:0000904 cell morphogenesis involved in differentiation
1.58 1.15e-04 GO:0010604 positive regulation of macromolecule metabolic process
2.66 1.31e-04 GO:0030900 forebrain development
1.74 1.43e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.93 1.49e-04 GO:0031175 neuron projection development
2.89 1.58e-04 GO:0007156 homophilic cell adhesion
2.02 1.59e-04 GO:0016477 cell migration
1.78 1.99e-04 GO:0051254 positive regulation of RNA metabolic process
1.68 2.74e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.90 3.06e-04 GO:0048858 cell projection morphogenesis
1.67 3.46e-04 GO:0009891 positive regulation of biosynthetic process
1.50 3.68e-04 GO:0009966 regulation of signal transduction
1.71 3.87e-04 GO:0007267 cell-cell signaling
1.96 3.97e-04 GO:0032583 regulation of gene-specific transcription
1.88 4.33e-04 GO:0032990 cell part morphogenesis
2.34 4.97e-04 GO:0048568 embryonic organ development
2.10 5.35e-04 GO:0045597 positive regulation of cell differentiation
1.63 5.39e-04 GO:0009611 response to wounding
1.65 5.81e-04 GO:0009888 tissue development
1.70 6.43e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.93 6.49e-04 GO:0050776 regulation of immune response
1.88 7.04e-04 GO:0019226 transmission of nerve impulse
1.88 7.04e-04 GO:0035637 multicellular organismal signaling
1.68 7.46e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.59 1.01e-03 GO:0009605 response to external stimulus
1.91 1.08e-03 GO:0051094 positive regulation of developmental process
1.37 1.26e-03 GO:0048523 negative regulation of cellular process
1.81 1.64e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.80 1.77e-03 GO:0051253 negative regulation of RNA metabolic process
1.52 1.77e-03 GO:0031325 positive regulation of cellular metabolic process
2.07 1.89e-03 GO:0001501 skeletal system development
1.70 1.91e-03 GO:0009790 embryo development
1.74 1.91e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.87 2.37e-03 GO:0048870 cell motility
1.87 2.37e-03 GO:0051674 localization of cell
2.91 2.65e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.24 2.86e-03 GO:0048706 embryonic skeletal system development
1.74 3.11e-03 GO:0000902 cell morphogenesis
2.69 3.21e-03 GO:0001503 ossification
2.54 3.31e-03 GO:0048562 embryonic organ morphogenesis
1.34 3.32e-03 GO:0048519 negative regulation of biological process
1.69 3.47e-03 GO:0031327 negative regulation of cellular biosynthetic process
3.02 3.54e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.20 3.60e-03 GO:0030097 hemopoiesis
1.72 4.37e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.14 4.41e-03 GO:0045596 negative regulation of cell differentiation
1.87 4.49e-03 GO:0007268 synaptic transmission
2.90 4.53e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.23 4.58e-03 GO:0002253 activation of immune response
1.75 6.00e-03 GO:0006928 cellular component movement
1.84 6.32e-03 GO:0008283 cell proliferation
1.70 6.49e-03 GO:0032989 cellular component morphogenesis
1.97 6.58e-03 GO:0007389 pattern specification process
1.78 6.76e-03 GO:0006935 chemotaxis
1.78 6.76e-03 GO:0042330 taxis
2.53 7.98e-03 GO:0001655 urogenital system development
1.65 8.16e-03 GO:0009890 negative regulation of biosynthetic process
1.93 8.46e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.99 9.35e-03 GO:0060284 regulation of cell development
2.16 1.04e-02 GO:0030168 platelet activation
1.77 1.08e-02 GO:0048585 negative regulation of response to stimulus
1.46 1.23e-02 GO:0010033 response to organic substance
1.90 1.32e-02 GO:0048598 embryonic morphogenesis
1.38 1.42e-02 GO:0003008 system process
3.05 1.45e-02 GO:0042063 gliogenesis
7.77 1.77e-02 GO:0021602 cranial nerve morphogenesis
1.71 1.82e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
3.88 1.88e-02 GO:0048663 neuron fate commitment
1.72 2.03e-02 GO:0023056 positive regulation of signaling
3.29 2.44e-02 GO:0032526 response to retinoic acid
2.02 2.74e-02 GO:0048534 hemopoietic or lymphoid organ development
1.71 3.16e-02 GO:0010647 positive regulation of cell communication
1.66 3.21e-02 GO:0010629 negative regulation of gene expression
1.64 3.22e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.23 3.96e-02 GO:0002764 immune response-regulating signaling pathway
1.61 4.31e-02 GO:0009719 response to endogenous stimulus
1.98 4.47e-02 GO:0051960 regulation of nervous system development
1.80 4.62e-02 GO:0009968 negative regulation of signal transduction
1.31 4.76e-02 GO:0065008 regulation of biological quality
1.61 4.93e-02 GO:0010558 negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 5.44e-14 GO:0044459 plasma membrane part
1.37 8.05e-12 GO:0005886 plasma membrane
1.36 3.53e-11 GO:0071944 cell periphery
1.71 1.02e-09 GO:0031226 intrinsic to plasma membrane
1.71 1.59e-09 GO:0005887 integral to plasma membrane
1.98 6.09e-05 GO:0043005 neuron projection
1.86 9.87e-04 GO:0045202 synapse
1.56 3.42e-03 GO:0005615 extracellular space
1.81 5.77e-03 GO:0009986 cell surface
1.46 6.63e-03 GO:0044421 extracellular region part
1.49 1.15e-02 GO:0042995 cell projection
1.96 2.09e-02 GO:0000785 chromatin

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.15 4.68e-19 GO:0001071 nucleic acid binding transcription factor activity
2.15 4.68e-19 GO:0003700 sequence-specific DNA binding transcription factor activity
2.39 5.59e-18 GO:0043565 sequence-specific DNA binding
1.87 2.85e-11 GO:0030528 transcription regulator activity
1.13 5.68e-11 GO:0005488 binding
1.46 2.34e-08 GO:0003677 DNA binding
4.75 3.28e-07 GO:0004879 ligand-dependent nuclear receptor activity
1.89 4.66e-07 GO:0005509 calcium ion binding
4.79 7.12e-07 GO:0003707 steroid hormone receptor activity
1.18 7.97e-06 GO:0005515 protein binding
1.39 8.21e-05 GO:0004871 signal transducer activity
1.39 8.21e-05 GO:0060089 molecular transducer activity
4.58 1.75e-04 GO:0003823 antigen binding
10.46 1.28e-03 GO:0003708 retinoic acid receptor activity
1.38 2.98e-03 GO:0004872 receptor activity
2.18 4.81e-03 GO:0000975 regulatory region DNA binding
2.18 4.81e-03 GO:0001067 regulatory region nucleic acid binding
2.18 4.81e-03 GO:0044212 transcription regulatory region DNA binding
1.22 6.20e-03 GO:0046872 metal ion binding
1.90 7.62e-03 GO:0016563 transcription activator activity
2.14 1.23e-02 GO:0010843 promoter binding
1.21 1.23e-02 GO:0043167 ion binding
3.33 1.60e-02 GO:0042562 hormone binding
1.20 1.73e-02 GO:0043169 cation binding
1.70 3.18e-02 GO:0008289 lipid binding
1.22 3.70e-02 GO:0003676 nucleic acid binding
1.43 3.98e-02 GO:0005102 receptor binding