Motif ID: POU6F1.p2

Z-value: 1.140


Transcription factors associated with POU6F1.p2:

Gene SymbolEntrez IDGene Name
POU6F1 5463 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU6F1chr12_-_516114760.371.2e-08Click!


Activity profile for motif POU6F1.p2.

activity profile for motif POU6F1.p2


Sorted Z-values histogram for motif POU6F1.p2

Sorted Z-values for motif POU6F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_74422920 26.742 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr13_-_45010974 25.609 TSC22D1
TSC22 domain family, member 1
chr15_+_74422742 24.837 NM_020851
 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr10_+_5005685 24.518 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr13_-_45010994 23.675 TSC22D1
TSC22 domain family, member 1
chr13_-_45010937 23.424 TSC22D1
TSC22 domain family, member 1
chr22_+_22735134 19.958 CYAT1
immunoglobulin lambda light chain-like
chr10_+_5005601 15.902 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5005453 15.600 NM_001353
 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr22_+_22786283 15.530


chrX_+_135278912 15.232 NM_001159701
NM_001159699
 FHL1

four and a half LIM domains 1

chr12_-_51611476 13.727 POU6F1
POU class 6 homeobox 1
chr13_-_45011389 13.561 NM_001243797
 TSC22D1
TSC22 domain family, member 1
chr12_-_91572328 11.820 NM_133504
NM_133505
NM_133506
NM_133507
 DCN



decorin



chr9_-_95166827 11.589 NM_014057
NM_033014
 OGN

osteoglycin

chr2_+_113816214 10.796 NM_173170
 IL36RN
interleukin 36 receptor antagonist
chr13_-_45011059 10.486 NM_006022
 TSC22D1
TSC22 domain family, member 1
chr4_+_70861647 10.476 NM_001009181
NM_003154
 STATH

statherin

chrX_+_67913479 10.441 NM_001142504
 STARD8
StAR-related lipid transfer (START) domain containing 8
chr22_+_39101954 10.186 GTPBP1
GTP binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
29.60 5.16e-03 GO:0030502 negative regulation of bone mineralization
25.90 1.02e-02 GO:0070168 negative regulation of biomineral tissue development
4.27 1.36e-02 GO:0006936 muscle contraction
3.92 3.37e-02 GO:0003012 muscle system process
3.55 2.68e-02 GO:0008202 steroid metabolic process
1.84 2.58e-03 GO:0048513 organ development
1.57 2.86e-02 GO:0048731 system development
1.44 1.23e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
14.39 3.44e-03 GO:0032982 myosin filament
2.37 5.58e-04 GO:0005615 extracellular space
2.17 4.87e-03 GO:0005626 insoluble fraction
2.17 6.32e-03 GO:0005624 membrane fraction
2.14 8.22e-04 GO:0044421 extracellular region part
2.02 9.85e-04 GO:0005887 integral to plasma membrane
1.98 1.60e-03 GO:0031226 intrinsic to plasma membrane
1.88 2.85e-05 GO:0005576 extracellular region
1.81 7.72e-05 GO:0044459 plasma membrane part
1.40 1.49e-02 GO:0005886 plasma membrane
1.40 1.65e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
38.85 8.04e-03 GO:0047023 androsterone dehydrogenase activity
38.85 8.04e-03 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
10.79 2.33e-02 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
9.07 2.87e-03 GO:0003823 antigen binding
7.23 4.69e-02 GO:0008307 structural constituent of muscle
2.97 1.16e-02 GO:0003779 actin binding