Motif ID: PRDM1.p3

Z-value: 1.332


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRDM1chr6_+_106534188-0.009.6e-01Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_32821924 33.126 NM_002800
 PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr14_+_24605366 28.001 NM_006263
NM_176783
 PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

chr14_+_24605393 25.340 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr16_-_67970734 24.079 NM_002801
 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_-_111746917 23.945 DENND2D
DENN/MADD domain containing 2D
chr16_-_67970651 19.706 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr11_+_63304272 18.779 NM_004585
 RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr12_+_25205180 16.582 NM_001204126
NM_001204127
NM_006152
 LRMP


lymphoid-restricted membrane protein


chrX_-_118827060 16.235 SEPT6
septin 6
chr6_-_32811773 16.184 NM_148919
 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chrX_-_118827322 15.257 NM_015129
NM_145799
NM_145800
NM_145802
 SEPT6



septin 6



chr2_-_231084600 14.627 NM_004509
NM_004510
NM_080424
 SP110


SP110 nuclear body protein


chr1_+_212781969 14.605 NM_001040619
NM_001206484
NM_001206488
NM_001674
 ATF3



activating transcription factor 3



chr3_-_49851217 14.138 UBA7
ubiquitin-like modifier activating enzyme 7
chr6_-_33282006 13.843 NM_003190
NM_172208
NM_172209
 TAPBP


TAP binding protein (tapasin)


chr5_+_96212167 13.379 ERAP2
endoplasmic reticulum aminopeptidase 2
chr5_-_142815076 13.357 NM_001018074
NM_001018075
NM_001018077
 NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr3_-_49851356 13.287 NM_003335
 UBA7
ubiquitin-like modifier activating enzyme 7
chr14_-_69262959 12.836 NM_001244701
 ZFP36L1
zinc finger protein 36, C3H type-like 1
chr2_+_231280906 12.365 SP100
SP100 nuclear antigen

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 98 entries
enrichment   p-value GO term description
79.47 3.86e-05 GO:0002483 antigen processing and presentation of endogenous peptide antigen
79.47 3.86e-05 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
56.77 2.66e-04 GO:0019883 antigen processing and presentation of endogenous antigen
49.67 1.54e-02 GO:0016553 base conversion or substitution editing
30.57 5.18e-03 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
19.87 3.32e-02 GO:0048002 antigen processing and presentation of peptide antigen
19.87 3.32e-02 GO:0070206 protein trimerization
15.00 4.25e-05 GO:0006521 regulation of cellular amino acid metabolic process
13.03 1.32e-04 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
13.03 1.32e-04 GO:0072395 signal transduction involved in cell cycle checkpoint
13.03 1.32e-04 GO:0072401 signal transduction involved in DNA integrity checkpoint
13.03 1.32e-04 GO:0072404 signal transduction involved in G1/S transition checkpoint
13.03 1.32e-04 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
13.03 1.32e-04 GO:0072422 signal transduction involved in DNA damage checkpoint
13.03 1.32e-04 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
13.03 1.32e-04 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
12.82 1.50e-04 GO:0060337 type I interferon-mediated signaling pathway
12.82 1.50e-04 GO:0071357 cellular response to type I interferon
12.62 1.70e-04 GO:0034340 response to type I interferon
12.42 1.93e-04 GO:0033238 regulation of cellular amine metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
99.34 1.45e-02 GO:0071797 LUBAC complex
66.23 4.33e-02 GO:0005588 collagen type V
66.23 4.33e-02 GO:0008537 proteasome activator complex
66.23 4.33e-02 GO:0030895 apolipoprotein B mRNA editing enzyme complex
29.81 4.76e-06 GO:0005839 proteasome core complex
14.20 1.85e-06 GO:0000502 proteasome complex
1.48 5.44e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
28.39 7.66e-06 GO:0004298 threonine-type endopeptidase activity
28.39 7.66e-06 GO:0070003 threonine-type peptidase activity
12.82 4.23e-02 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
3.64 1.08e-02 GO:0004175 endopeptidase activity
3.42 9.62e-04 GO:0070011 peptidase activity, acting on L-amino acid peptides
3.30 1.57e-03 GO:0008233 peptidase activity
2.08 8.69e-04 GO:0008270 zinc ion binding
1.87 7.86e-03 GO:0046914 transition metal ion binding
1.39 4.96e-03 GO:0005515 protein binding
1.23 7.57e-04 GO:0005488 binding