Motif ID: PRRX1,2.p2

Z-value: 1.461


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRRX1chr1_+_1706333120.221.2e-03Click!
PRRX2chr9_+_132428016-0.072.8e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_94297448 44.215 PEG10
paternally expressed 10
chr5_+_71502700 38.959 MAP1B
microtubule-associated protein 1B
chr1_+_151032683 37.103 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032866 36.400 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032880 36.304 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr4_-_176733413 26.168 GPM6A
glycoprotein M6A
chr2_-_55199894 26.006


chr1_+_84630575 22.553 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chrX_-_13835012 21.858 GPM6B
glycoprotein M6B
chr3_+_158787040 21.134 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr2_-_44586854 20.599 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr4_-_176733901 19.092 GPM6A
glycoprotein M6A
chr3_-_25683825 18.512 TOP2B
topoisomerase (DNA) II beta 180kDa
chr2_-_55237255 18.380 NM_007008
RTN4
reticulon 4
chrX_+_114827818 17.269 NM_001136025
NM_001172335
PLS3

plastin 3

chr1_+_84630374 17.049 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_159557745 16.989 SCHIP1
schwannomin interacting protein 1
chr17_-_1248346 16.812 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr4_+_158141735 16.503 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr12_-_46633551 15.996 SLC38A1
solute carrier family 38, member 1
chr10_+_111765725 15.894 NM_019903
ADD3
adducin 3 (gamma)
chr6_-_75970566 15.500 TMEM30A
transmembrane protein 30A
chr3_+_159557649 15.237 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr6_-_75965845 14.764 TMEM30A
transmembrane protein 30A
chr10_+_102123420 14.441


chr1_+_100316530 14.319 NM_000646
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr21_+_30400229 14.222 USP16
ubiquitin specific peptidase 16
chr5_+_65372744 14.109 ERBB2IP
erbb2 interacting protein
chr1_+_84630014 13.755 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr12_+_28410132 13.689 NM_018318
CCDC91
coiled-coil domain containing 91
chr1_+_84647342 13.655 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr18_-_21891469 13.598 NM_001242508
OSBPL1A
oxysterol binding protein-like 1A
chr6_+_64231626 13.535 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr21_-_27253197 13.481 APP
amyloid beta (A4) precursor protein
chrX_+_123234462 13.466 STAG2
stromal antigen 2
chr3_+_361365 13.364 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr4_-_83347222 13.036 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr14_+_62164339 12.974 NM_001243084
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr8_+_80523351 12.655 STMN2
stathmin-like 2
chr10_+_28878666 12.648 WAC
WW domain containing adaptor with coiled-coil
chr1_-_93342706 12.538 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr14_+_101295409 12.511 MEG3
maternally expressed 3 (non-protein coding)
chr2_+_187454724 12.442 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr4_-_74088773 12.300 ANKRD17
ankyrin repeat domain 17
chr17_+_28268622 11.975 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr3_-_196911001 11.866 NM_001204387
NM_001204388
DLG1

discs, large homolog 1 (Drosophila)

chr17_+_48821106 11.726 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr4_-_88450243 11.712 SPARCL1
SPARC-like 1 (hevin)
chr10_+_63808968 11.644 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chrX_+_107288199 11.586 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr8_+_107738239 11.349 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr9_-_14086901 11.279 NFIB
nuclear factor I/B
chr8_-_17555158 11.179 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr6_+_158733691 11.123 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr18_-_53089722 10.895 NM_001243233
TCF4
transcription factor 4
chr2_-_224467095 10.795 SCG2
secretogranin II
chr6_+_83072922 10.691 NM_006670
TPBG
trophoblast glycoprotein
chr1_-_151414641 10.544 NM_207171
POGZ
pogo transposable element with ZNF domain
chr5_+_34687663 10.502 NM_001145523
RAI14
retinoic acid induced 14
chr8_+_80523376 10.454 STMN2
stathmin-like 2
chr5_+_36606667 10.450 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_176734181 10.437 NM_201591
GPM6A
glycoprotein M6A
chr8_+_80523304 10.368 STMN2
stathmin-like 2
chr8_+_80523339 10.107 STMN2
stathmin-like 2
chr2_-_44587812 10.004 NM_006036
PREPL
prolyl endopeptidase-like
chr3_+_158991035 9.949 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr12_-_102512277 9.945 NM_024057
NUP37
nucleoporin 37kDa
chr6_-_38670915 9.806 GLO1
glyoxalase I
chr14_+_67831484 9.748 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_+_62934030 9.745 NM_001142614
EHBP1
EH domain binding protein 1
chr2_-_224467142 9.692 NM_003469
SCG2
secretogranin II
chr12_-_50595303 9.489 NM_001243775
LIMA1
LIM domain and actin binding 1
chr12_-_50616425 9.455 NM_001113547
LIMA1
LIM domain and actin binding 1
chr7_-_26232148 9.437 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr13_+_53035227 9.418 CKAP2
cytoskeleton associated protein 2
chr12_+_64803741 9.371 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr11_+_87032428 9.348 TMEM135
transmembrane protein 135
chr5_+_36606456 9.201 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr10_-_98290309 9.151 TM9SF3
transmembrane 9 superfamily member 3
chr1_-_115268890 8.968 CSDE1
cold shock domain containing E1, RNA-binding
chr11_-_115088628 8.760 CADM1
cell adhesion molecule 1
chr6_-_46293628 8.723 NM_005822
RCAN2
regulator of calcineurin 2
chr6_-_131321868 8.691 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_+_50574601 8.669 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_-_195310770 8.609 APOD
apolipoprotein D
chr2_+_172821874 8.550 HAT1
histone acetyltransferase 1
chr3_+_130569368 8.516 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr3_+_111717585 8.510 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr6_-_84419018 8.441 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr22_-_36236264 8.309 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_-_38670922 8.230 NM_006708
GLO1
glyoxalase I
chr2_-_224467049 8.202 SCG2
secretogranin II
chr6_-_38670904 8.164 GLO1
glyoxalase I
chr20_+_9288446 8.120 NM_000933
PLCB4
phospholipase C, beta 4
chr3_+_142342265 8.105 NM_002670
PLS1
plastin 1
chr2_-_48115846 8.104 NM_025133
FBXO11
F-box protein 11
chr4_+_41700736 8.069 LIMCH1
LIM and calponin homology domains 1
chr3_+_35722428 8.039 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr6_-_38670882 8.021 GLO1
glyoxalase I
chr12_-_16759733 7.995 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_121756744 7.972 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chrX_-_13835187 7.866 GPM6B
glycoprotein M6B
chr14_+_56078735 7.852 KTN1
kinectin 1 (kinesin receptor)
chr6_+_87969619 7.801 ZNF292
zinc finger protein 292
chr22_-_36236330 7.762 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_-_84419108 7.702 NM_001242793
NM_001242794
NM_014841
SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr13_+_36050885 7.679 NM_001204197
NBEA
neurobeachin
chr1_+_50569581 7.600 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr8_+_80523048 7.589 NM_001199214
NM_007029
STMN2

stathmin-like 2

chr22_-_36236421 7.565 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr10_+_91498724 7.538 KIF20B
kinesin family member 20B
chr16_+_7382750 7.519 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr2_+_210444154 7.424 MAP2
microtubule-associated protein 2
chr1_-_103496768 7.421 COL11A1
collagen, type XI, alpha 1
chr14_-_20801427 7.386 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr12_-_16759430 7.386 LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_35721115 7.383 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr12_-_16759939 7.301 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr15_-_25650647 7.275 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr2_-_200325200 7.169 SATB2
SATB homeobox 2
chr2_-_61764661 7.051 XPO1
exportin 1 (CRM1 homolog, yeast)
chr5_+_71403040 7.047 NM_005909
MAP1B
microtubule-associated protein 1B
chr3_+_141043054 6.965 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr15_+_32933869 6.950 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr8_-_62602285 6.930 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr7_-_7758237 6.796 NM_002947
RPA3
replication protein A3, 14kDa
chr15_-_56209305 6.776 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr2_+_183608329 6.769 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr2_+_170662044 6.669 SSB
Sjogren syndrome antigen B (autoantigen La)
chrX_-_13835313 6.638 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr4_+_169013687 6.634 NM_007193
ANXA10
annexin A10
chr7_-_107880492 6.632 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr9_-_114247024 6.587 NM_001080398
KIAA0368
KIAA0368
chrX_-_10535476 6.497 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr1_+_50574589 6.476 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr11_-_73471136 6.467 NM_001243719
RAB6A
RAB6A, member RAS oncogene family
chr1_+_92632608 6.398 NM_015237
KIAA1107
KIAA1107
chr10_+_63661012 6.389 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr14_+_70236266 6.379 SRSF5
serine/arginine-rich splicing factor 5
chr12_-_16760935 6.336 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr2_-_225378320 6.291 CUL3
cullin 3
chr5_+_132432880 6.278 HSPA4
heat shock 70kDa protein 4
chr18_+_33234532 6.270 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr6_-_38670871 6.246 GLO1
glyoxalase I
chr14_+_61201450 6.220 NM_001177963
NM_002431
MNAT1

menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)

chr12_+_50869531 6.192 LARP4
La ribonucleoprotein domain family, member 4
chr8_-_110661007 6.148 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr13_-_24007822 6.141 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr6_-_79675672 6.137 PHIP
pleckstrin homology domain interacting protein
chr4_+_146031528 6.119 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr2_-_225370687 6.057 CUL3
cullin 3
chr4_+_41614725 5.945 LIMCH1
LIM and calponin homology domains 1
chr4_+_88896899 5.933 SPP1
secreted phosphoprotein 1
chr12_-_56679729 5.900 CS
citrate synthase
chr5_+_36608430 5.879 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_20527120 5.870 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr4_+_88896838 5.868 SPP1
secreted phosphoprotein 1
chr3_+_115342302 5.864 GAP43
growth associated protein 43
chr12_-_54653369 5.842 NM_001127321
CBX5
chromobox homolog 5
chr7_+_112063131 5.841 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr21_-_27512668 5.826 NM_001136016
APP
amyloid beta (A4) precursor protein
chr8_+_66582107 5.815 NM_001145838
MTFR1
mitochondrial fission regulator 1
chrX_-_13835213 5.798 GPM6B
glycoprotein M6B
chr4_-_139163222 5.717 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_+_102508333 5.681 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_102508377 5.674 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_20512016 5.641 PUM2
pumilio homolog 2 (Drosophila)
chr11_+_69467210 5.608 CCND1
cyclin D1
chr20_+_11898536 5.606 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr1_+_163038934 5.584 NM_001113381
RGS4
regulator of G-protein signaling 4
chr1_+_115572414 5.576 NM_000549
TSHB
thyroid stimulating hormone, beta
chr3_-_195310985 5.565 NM_001647
APOD
apolipoprotein D
chr6_-_6007097 5.560 NRN1
neuritin 1
chr5_+_125758818 5.513 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr12_+_75784878 5.492 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr4_+_166131170 5.486 NM_001161521
NM_001161522
KLHL2

kelch-like 2, Mayven (Drosophila)

chr13_-_36429798 5.481 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr2_-_10942642 5.476 PDIA6
protein disulfide isomerase family A, member 6
chr6_-_86351156 5.411 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr1_+_67632168 5.385 NM_144701
IL23R
interleukin 23 receptor
chr12_-_71551564 5.381 TSPAN8
tetraspanin 8
chr6_+_64286348 5.297 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr8_-_110620220 5.229 SYBU
syntabulin (syntaxin-interacting)
chr1_+_15990300 5.171


chr11_+_43665772 5.164


chr9_-_14398981 5.147 NM_001190738
NFIB
nuclear factor I/B
chr12_-_54653317 5.136 NM_001127322
CBX5
chromobox homolog 5
chr12_-_16759531 5.113 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_-_95241943 5.102 NM_013451
NM_133337
MYOF

myoferlin

chr5_+_125695787 5.085 NM_001146319
GRAMD3
GRAM domain containing 3
chr8_+_98703361 5.027 MTDH
metadherin
chr1_-_23886284 5.019 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_-_17191287 4.914 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr5_+_147795459 4.905 FBXO38
F-box protein 38
chr5_+_179132676 4.891 CANX
calnexin
chr15_+_66694216 4.878 MAP2K1
mitogen-activated protein kinase kinase 1
chr17_-_35656691 4.874 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr19_+_30863318 4.859 NM_014717
ZNF536
zinc finger protein 536
chr10_-_118680978 4.820 KIAA1598
KIAA1598
chr5_-_86703927 4.816 CCNH
cyclin H

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.17 1.59e-23 GO:0009987 cellular process
1.27 1.60e-09 GO:0044260 cellular macromolecule metabolic process
1.23 6.19e-08 GO:0043170 macromolecule metabolic process
1.34 1.27e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.33 7.99e-07 GO:0071842 cellular component organization at cellular level
1.15 9.16e-07 GO:0065007 biological regulation
1.18 1.05e-06 GO:0044237 cellular metabolic process
1.45 2.25e-06 GO:0007399 nervous system development
1.16 2.33e-06 GO:0050794 regulation of cellular process
1.17 2.79e-06 GO:0044238 primary metabolic process
1.30 5.75e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 1.13e-05 GO:0034641 cellular nitrogen compound metabolic process
1.15 1.61e-05 GO:0050789 regulation of biological process
1.25 1.64e-05 GO:0071840 cellular component organization or biogenesis
1.15 2.69e-05 GO:0008152 metabolic process
1.26 3.91e-05 GO:0006807 nitrogen compound metabolic process
1.32 4.41e-05 GO:0090304 nucleic acid metabolic process
1.25 6.42e-05 GO:0016043 cellular component organization
1.30 9.11e-05 GO:0048519 negative regulation of biological process
1.34 1.80e-04 GO:0010467 gene expression
1.22 2.25e-04 GO:0023052 signaling
1.26 2.84e-04 GO:0048731 system development
1.20 4.50e-04 GO:0051716 cellular response to stimulus
1.24 4.54e-04 GO:0048856 anatomical structure development
1.27 6.21e-04 GO:0044267 cellular protein metabolic process
1.35 7.12e-04 GO:0006996 organelle organization
1.22 1.57e-03 GO:0007165 signal transduction
1.28 2.46e-03 GO:0048523 negative regulation of cellular process
1.54 3.84e-03 GO:0006396 RNA processing
1.58 3.90e-03 GO:0000278 mitotic cell cycle
1.19 5.48e-03 GO:0032502 developmental process
2.21 6.86e-03 GO:0007156 homophilic cell adhesion
1.22 7.27e-03 GO:0019538 protein metabolic process
1.25 1.10e-02 GO:0048522 positive regulation of cellular process
1.30 1.16e-02 GO:0016070 RNA metabolic process
1.45 1.28e-02 GO:0022402 cell cycle process
4.88 1.55e-02 GO:0007026 negative regulation of microtubule depolymerization
1.20 1.66e-02 GO:0007275 multicellular organismal development
1.39 1.92e-02 GO:0007049 cell cycle
2.73 2.00e-02 GO:0030518 steroid hormone receptor signaling pathway
1.55 2.27e-02 GO:0044265 cellular macromolecule catabolic process
1.74 2.97e-02 GO:0016337 cell-cell adhesion
1.45 3.07e-02 GO:2000026 regulation of multicellular organismal development
4.60 3.32e-02 GO:0031114 regulation of microtubule depolymerization
1.47 3.35e-02 GO:0022403 cell cycle phase
1.72 3.39e-02 GO:0051325 interphase
3.21 3.56e-02 GO:0030521 androgen receptor signaling pathway
1.72 3.77e-02 GO:0051329 interphase of mitotic cell cycle
1.66 3.92e-02 GO:0044419 interspecies interaction between organisms
1.70 4.83e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.69 4.86e-02 GO:0019941 modification-dependent protein catabolic process
1.28 4.95e-02 GO:0009059 macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 9.28e-15 GO:0005737 cytoplasm
1.12 7.86e-13 GO:0044424 intracellular part
1.11 7.02e-12 GO:0005622 intracellular
1.13 2.79e-10 GO:0043229 intracellular organelle
1.13 5.53e-10 GO:0043226 organelle
1.21 4.16e-09 GO:0044422 organelle part
1.20 8.37e-09 GO:0044444 cytoplasmic part
1.14 1.70e-08 GO:0043231 intracellular membrane-bounded organelle
1.21 2.07e-08 GO:0044446 intracellular organelle part
1.14 2.43e-08 GO:0043227 membrane-bounded organelle
1.36 2.07e-07 GO:0044428 nuclear part
1.38 5.17e-07 GO:0031981 nuclear lumen
1.33 6.13e-07 GO:0043233 organelle lumen
1.33 8.74e-07 GO:0070013 intracellular organelle lumen
1.32 1.39e-06 GO:0031974 membrane-enclosed lumen
1.33 5.67e-06 GO:0005829 cytosol
1.43 7.00e-06 GO:0005654 nucleoplasm
1.28 8.32e-06 GO:0043228 non-membrane-bounded organelle
1.28 8.32e-06 GO:0043232 intracellular non-membrane-bounded organelle
1.16 6.98e-05 GO:0005634 nucleus
1.22 7.88e-05 GO:0032991 macromolecular complex
1.57 2.30e-03 GO:0005730 nucleolus
1.21 2.43e-03 GO:0043234 protein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.27 2.52e-24 GO:0005515 protein binding
1.12 7.81e-14 GO:0005488 binding
1.50 6.32e-06 GO:0005102 receptor binding
1.53 6.60e-04 GO:0005509 calcium ion binding
2.21 2.82e-02 GO:0051427 hormone receptor binding