Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 3.926


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFXANKchr19_+_19303732-0.651.0e-27Click!
RFX5chr1_-_151319717-0.551.1e-18Click!
RFX2chr19_-_61104910.533.3e-17Click!
RFX1chr19_-_141170960.339.2e-07Click!
RFX3chr9_-_35259730.321.2e-06Click!
RFXAPchr13_+_373933060.211.8e-03Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_48693934 120.976 NM_013271
 PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_-_62473502 102.367 NM_001130702
NM_032667
 BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr5_-_149669400 96.744 NM_015981
NM_171825
 CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr15_+_71184781 84.004 NM_001199017
NM_017691
NM_001199018
 LRRC49


leucine rich repeat containing 49


chr14_-_60337350 82.734 NM_021136
 RTN1
reticulon 1
chr3_-_58563070 77.569 FAM107A
family with sequence similarity 107, member A
chr16_+_8806825 74.745 NM_000663
 ABAT
4-aminobutyrate aminotransferase
chr11_+_133938819 74.342 NM_001205329
NM_032801
 JAM3

junctional adhesion molecule 3

chr2_-_175869910 72.137 NM_001822
NM_001025201
 CHN1

chimerin (chimaerin) 1

chr15_-_71184611 68.310 NM_020147
 THAP10
THAP domain containing 10
chr11_+_133938965 64.937 JAM3
junctional adhesion molecule 3
chr19_-_55690717 64.808 SYT5
synaptotagmin V
chr14_-_74180341 63.828 NM_006029
 PNMA1
paraneoplastic antigen MA1
chr17_-_5404304 58.504 NM_001162371
 LOC728392
uncharacterized LOC728392
chr19_-_46974663 57.496 PNMAL1
PNMA-like 1
chr5_-_149669187 56.778 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr17_-_74137370 56.355 NM_001454
 FOXJ1
forkhead box J1
chr20_+_43991739 55.130 NM_001099791
NM_033542
 SYS1-DBNDD2
SYS1

SYS1-DBNDD2 readthrough
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr6_+_88117689 54.858 NM_001031743
 C6orf165
chromosome 6 open reading frame 165
chr1_-_204380903 54.855 NM_032833
 PPP1R15B
protein phosphatase 1, regulatory subunit 15B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
7.83 4.84e-04 GO:0042384 cilium assembly
6.20 1.62e-03 GO:0060271 cilium morphogenesis
4.59 2.77e-03 GO:0030031 cell projection assembly
2.01 2.83e-02 GO:0030030 cell projection organization

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
15.66 1.76e-03 GO:0005952 cAMP-dependent protein kinase complex
14.10 2.79e-02 GO:0034464 BBSome
10.84 1.60e-02 GO:0060170 cilium membrane
6.56 5.56e-04 GO:0005932 microtubule basal body
6.32 2.57e-05 GO:0005930 axoneme
5.73 8.79e-05 GO:0044441 cilium part
5.52 8.13e-03 GO:0019861 flagellum
5.50 2.32e-02 GO:0035085 cilium axoneme
4.30 2.11e-07 GO:0005929 cilium
3.60 3.41e-02 GO:0005875 microtubule associated complex
2.93 6.64e-05 GO:0005874 microtubule
2.44 3.94e-03 GO:0005815 microtubule organizing center
2.35 1.96e-06 GO:0015630 microtubule cytoskeleton
1.51 4.76e-02 GO:0005856 cytoskeleton
1.23 3.30e-05 GO:0005737 cytoplasm
1.15 3.84e-05 GO:0005622 intracellular
1.15 6.15e-05 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.48 2.10e-02 GO:0017076 purine nucleotide binding
1.48 2.79e-02 GO:0032553 ribonucleotide binding
1.48 2.79e-02 GO:0032555 purine ribonucleotide binding