Motif ID: RXRG_dimer.p3

Z-value: 1.520


Transcription factors associated with RXRG_dimer.p3:

Gene SymbolEntrez IDGene Name
NR1H2 7376 nuclear receptor subfamily 1, group H, member 2
PPARA 5465 peroxisome proliferator-activated receptor alpha
PPARG 5468 peroxisome proliferator-activated receptor gamma
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RXRBchr6_-_33168448-0.631.7e-25Click!
PPARAchr22_+_46546498-0.412.0e-10Click!
RXRGchr1_-_165414499-0.202.5e-03Click!
RXRAchr9_+_137218324-0.195.6e-03Click!
PPARGchr3_+_12329332-0.054.4e-01Click!
NR1H2chr19_+_508796810.018.3e-01Click!


Activity profile for motif RXRG_dimer.p3.

activity profile for motif RXRG_dimer.p3


Sorted Z-values histogram for motif RXRG_dimer.p3

Sorted Z-values for motif RXRG_dimer.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRG_dimer.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_96252770 50.645 SNRPF
small nuclear ribonucleoprotein polypeptide F
chr7_-_65447233 39.587 NM_000181
GUSB
glucuronidase, beta
chr7_-_65447187 38.968 GUSB
glucuronidase, beta
chr12_+_96252705 38.861 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr7_-_65447206 37.729 GUSB
glucuronidase, beta
chr7_-_65447162 36.059 GUSB
glucuronidase, beta
chr7_-_139763520 35.402 NM_022750
PARP12
poly (ADP-ribose) polymerase family, member 12
chr2_+_109237679 35.294 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr8_-_80942488 34.893 NM_014018
MRPS28
mitochondrial ribosomal protein S28
chr3_-_150264134 33.262 SERP1
stress-associated endoplasmic reticulum protein 1
chr3_-_113465101 32.963 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_-_64246431 32.858 VPS54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr7_-_72936538 32.414 BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr1_-_40042461 31.331 PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr1_-_40042519 29.517 NM_001135653
NM_001135654
NM_003819
PABPC4


poly(A) binding protein, cytoplasmic 4 (inducible form)


chr12_+_67663364 29.234 CAND1
cullin-associated and neddylation-dissociated 1
chr2_+_178257371 28.991 NM_003659
AGPS
alkylglycerone phosphate synthase
chr19_-_2328566 27.498 NM_016199
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_207024317 25.387 NM_001037663
NM_001959
NM_021121
EEF1B2


eukaryotic translation elongation factor 1 beta 2


chr2_+_207024614 25.152 EEF1B2
eukaryotic translation elongation factor 1 beta 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
5.86 6.60e-03 GO:0006457 protein folding
1.94 2.17e-02 GO:0009058 biosynthetic process
1.64 3.60e-05 GO:0044237 cellular metabolic process
1.54 2.10e-04 GO:0008152 metabolic process
1.54 2.52e-03 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
8.48 4.91e-02 GO:0070469 respiratory chain
4.89 4.48e-04 GO:0005743 mitochondrial inner membrane
4.48 1.15e-03 GO:0019866 organelle inner membrane
4.48 1.36e-02 GO:0005759 mitochondrial matrix
4.07 3.35e-04 GO:0005740 mitochondrial envelope
3.99 9.09e-04 GO:0031966 mitochondrial membrane
3.70 3.77e-05 GO:0044429 mitochondrial part
3.25 3.04e-08 GO:0005739 mitochondrion
2.85 1.61e-02 GO:0031967 organelle envelope
2.80 1.99e-02 GO:0031975 envelope
2.11 1.22e-03 GO:0031090 organelle membrane
1.83 9.01e-10 GO:0044444 cytoplasmic part
1.64 3.14e-02 GO:0032991 macromolecular complex
1.57 9.61e-04 GO:0044446 intracellular organelle part
1.55 1.68e-03 GO:0044422 organelle part
1.54 1.10e-07 GO:0005737 cytoplasm
1.37 9.91e-04 GO:0043231 intracellular membrane-bounded organelle
1.37 1.05e-03 GO:0043227 membrane-bounded organelle
1.30 4.95e-05 GO:0044424 intracellular part
1.29 8.63e-03 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
74.56 3.84e-02 GO:0004013 adenosylhomocysteinase activity
74.56 3.84e-02 GO:0016802 trialkylsulfonium hydrolase activity
29.83 1.26e-03 GO:0000062 fatty-acyl-CoA binding
15.12 3.00e-03 GO:0005504 fatty acid binding
9.99 2.30e-02 GO:0033293 monocarboxylic acid binding
7.92 1.27e-03 GO:0051082 unfolded protein binding
1.48 2.04e-04 GO:0005515 protein binding