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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SMAD1..7,9.p2

Z-value: 2.997

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_139871954	70.687	NM_000954	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr1_+_55464605	67.312	NM_057176	BSND	Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr9_+_139872014	54.535		PTGDS	prostaglandin D2 synthase 21kDa (brain)
chrX_-_70288155	45.006	NM_013346	SNX12	sorting nexin 12
chrX_-_106960028	41.185		TSC22D3	TSC22 domain family, member 3
chr5_-_58334936	37.968	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr9_+_124086842	36.532		GSN	gelsolin
chr3_-_195306274	35.699		APOD	apolipoprotein D
chr11_-_125366048	34.400	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr20_+_58515408	33.704	NM_001190827 NM_022106	C20orf177	chromosome 20 open reading frame 177
chrX_+_110339374	33.680	NM_002578	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr2_+_17721806	33.146	NM_003385	VSNL1	visinin-like 1
chr20_+_10199455	33.125	NM_003081 NM_130811	SNAP25	synaptosomal-associated protein, 25kDa
chr12_+_53443834	32.590	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr9_-_97402530	32.287	NM_001127628	FBP1	fructose-1,6-bisphosphatase 1
chr16_-_4466595	31.224		CORO7	coronin 7
chr21_+_41239346	29.187	NM_006198	PCP4	Purkinje cell protein 4
chr14_-_93651242	28.790	NM_022151	MOAP1	modulator of apoptosis 1
chr11_-_60719116	28.714	NM_016582	SLC15A3	solute carrier family 15, member 3
chr12_+_112451229	28.675
chr1_+_228645807	28.572	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr6_+_31949800	28.207	NM_001242823 NM_001252204 NM_007293 NM_001002029	LOC100293534 C4A C4B	complement C4-B-like complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr3_+_133465250	28.058		TF	transferrin
chr19_+_39897457	27.786	NM_003407	ZFP36	zinc finger protein 36, C3H type, homolog (mouse)
chr9_+_123963728	27.658		GSN	gelsolin
chr16_-_46865039	27.045	NM_001001436	C16orf87	chromosome 16 open reading frame 87
chr11_+_124609775	26.813	NM_001126181 NM_006176	NRGN	neurogranin (protein kinase C substrate, RC3)
chr2_+_17721983	26.712		VSNL1	visinin-like 1
chr16_-_3306586	26.435	NM_000243 NM_001198536	MEFV	Mediterranean fever
chr6_-_32163890	26.420		NOTCH4	notch 4
chr22_+_24891114	26.243	NM_016327	UPB1	ureidopropionase, beta
chr3_+_133465098	26.228		TF	transferrin
chr3_+_133464883	26.172	NM_001063	TF	transferrin
chrX_-_106959597	25.991	NM_001015881	TSC22D3	TSC22 domain family, member 3
chr3_+_133465204	25.868		TF	transferrin
chr14_-_106092256	25.829		IGHG4	immunoglobulin heavy constant gamma 4 (G4m marker)
chr12_+_57610577	25.732	NM_007224	NXPH4	neurexophilin 4
chr9_-_110251754	25.427		KLF4	Kruppel-like factor 4 (gut)
chr9_-_97402556	25.265		FBP1	fructose-1,6-bisphosphatase 1
chr1_+_184356227	25.154		C1orf21	chromosome 1 open reading frame 21
chr5_+_40909617	25.060		C7	complement component 7
chr11_-_117747331	24.775		FXYD6	FXYD domain containing ion transport regulator 6
chr2_+_149632836	24.656		KIF5C	kinesin family member 5C
chr3_-_39322763	24.448	NM_001171171	CX3CR1	chemokine (C-X3-C motif) receptor 1
chr4_-_174320616	24.049	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr1_-_36022938	23.738		KIAA0319L	KIAA0319-like
chr9_+_124048869	23.287		GSN	gelsolin
chr5_-_149535309	23.253		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr19_-_58326280	22.998	NM_024762	ZNF552	zinc finger protein 552
chr14_-_93651182	22.957		MOAP1	modulator of apoptosis 1
chr12_-_112450914	22.837	NM_001193453 NM_001193531 NM_138341	LOC728543 TMEM116	uncharacterized LOC728543 transmembrane protein 116
chr5_+_87564840	22.604		LOC100505894	uncharacterized LOC100505894
chr11_+_124609841	22.444		NRGN	neurogranin (protein kinase C substrate, RC3)
chr11_+_113931228	22.399	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chrX_-_13062720	22.072	NM_174901	FAM9C	family with sequence similarity 9, member C
chr5_+_40909558	21.794	NM_000587	C7	complement component 7
chr9_+_124043719	21.657		GSN	gelsolin
chr3_-_50349811	21.514	NM_153281	HYAL1	hyaluronoglucosaminidase 1
chr5_-_151066492	21.291	NM_003118	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr6_-_31514393	21.154		ATP6V1G2	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr3_+_111717585	21.150	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr4_+_187112936	21.118		CYP4V2	cytochrome P450, family 4, subfamily V, polypeptide 2
chr17_+_12692779	21.094	NM_014859	ARHGAP44	Rho GTPase activating protein 44
chr1_+_26644458	21.035		CD52	CD52 molecule
chr15_-_83953465	20.945	NM_001717	BNC1	basonuclin 1
chr9_-_97401746	20.815		FBP1	fructose-1,6-bisphosphatase 1
chr21_-_47878592	20.716
chr1_+_22351984	20.602		LINC00339	long intergenic non-protein coding RNA 339
chr6_+_41040713	20.256		NFYA	nuclear transcription factor Y, alpha
chr1_-_11714396	20.015		FBXO2	F-box protein 2
chr22_-_29711650	19.899	NM_001007279 NM_006477	RASL10A	RAS-like, family 10, member A
chrX_-_106960268	19.873	NM_004089	TSC22D3	TSC22 domain family, member 3
chr3_+_10068123	19.826		FANCD2	Fanconi anemia, complementation group D2
chr16_-_4466607	19.800		CORO7	coronin 7
chr2_+_149632772	19.744	NM_004522	KIF5C	kinesin family member 5C
chr1_+_26644380	19.733	NM_001803	CD52	CD52 molecule
chr8_-_134309448	19.651	NM_001135242 NM_006096	NDRG1	N-myc downstream regulated 1
chr8_+_21915371	19.615	NM_001114135	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr19_+_15783827	19.427	NM_023944	CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12
chr6_+_44355250	19.404	NM_001253	CDC5L	CDC5 cell division cycle 5-like (S. pombe)
chr1_+_159173802	19.401	NM_002036	DARC	Duffy blood group, chemokine receptor
chrX_-_107019001	19.363	NM_198057	TSC22D3	TSC22 domain family, member 3
chr11_-_64512925	19.309	NM_153819	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_22825481	19.285		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_-_155145732	19.130	NM_173852	KRTCAP2	keratinocyte associated protein 2
chr7_-_108166514	18.994		PNPLA8	patatin-like phospholipase domain containing 8
chr3_+_183967514	18.877		ECE2	endothelin converting enzyme 2
chr16_-_75498582	18.798	NM_145254	TMEM170A	transmembrane protein 170A
chr20_+_1246959	18.722	NM_014723	SNPH	syntaphilin
chr4_-_88450601	18.697	NM_001128310 NM_004684	SPARCL1	SPARC-like 1 (hevin)
chr1_-_36023005	18.393	NM_024874	KIAA0319L	KIAA0319-like
chr5_-_149535420	18.365	NM_002609	PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr3_+_183967414	18.333	NM_014693 NM_032331	ECE2	endothelin converting enzyme 2
chr2_-_211035913	18.271	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr3_+_35681008	18.215		ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr7_-_44228880	18.195	NM_000162	GCK	glucokinase (hexokinase 4)
chr16_+_2198607	18.187	NM_014353	RAB26	RAB26, member RAS oncogene family
chr1_-_16345284	18.030	NM_014424	HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr10_-_128077062	17.975		ADAM12	ADAM metallopeptidase domain 12
chr11_-_33890931	17.947		LMO2	LIM domain only 2 (rhombotin-like 1)
chr9_-_35111534	17.844		FAM214B	family with sequence similarity 214, member B
chr22_+_43808011	17.787	NM_001044370	MPPED1	metallophosphoesterase domain containing 1
chr1_-_11714471	17.730		FBXO2	F-box protein 2
chr8_+_142432006	17.611	NM_007079 NM_032611	PTP4A3	protein tyrosine phosphatase type IVA, member 3
chr22_-_46449972	17.458	NM_018280	C22orf26	chromosome 22 open reading frame 26
chrX_+_102000906	17.366	NM_001142529 NM_001142530	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr17_+_19437140	17.334	NM_018242	SLC47A1	solute carrier family 47, member 1
chr17_+_42385780	17.232	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr22_-_17690778	17.096	NM_017424	CECR1	cat eye syndrome chromosome region, candidate 1
chr19_-_21512148	16.894	NM_021269	ZNF708	zinc finger protein 708
chr17_-_62009620	16.794	NM_000626 NM_001039933 NM_021602	CD79B	CD79b molecule, immunoglobulin-associated beta
chr21_+_44394691	16.791		PKNOX1	PBX/knotted 1 homeobox 1
chr9_-_97401833	16.694	NM_000507	FBP1	fructose-1,6-bisphosphatase 1
chr17_+_41857802	16.688	NM_001136483	C17orf105	chromosome 17 open reading frame 105
chr12_-_109458844	16.557	NM_018711	SVOP	SV2 related protein homolog (rat)
chr16_-_4466570	16.523		CORO7-PAM16 CORO7	CORO7-PAM16 readthrough coronin 7
chrX_-_107018889	16.479		TSC22D3	TSC22 domain family, member 3
chr2_+_220283098	16.475	NM_001927	DES	desmin
chr11_-_66445318	16.387		RBM4B	RNA binding motif protein 4B
chr19_-_17414083	16.366	NM_024527	ABHD8	abhydrolase domain containing 8
chr5_+_113698304	16.332		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr6_+_41040687	16.147	NM_002505 NM_021705	NFYA	nuclear transcription factor Y, alpha
chr9_-_98079856	16.147	NM_000136 NM_001243744	FANCC	Fanconi anemia, complementation group C
chr10_+_74451838	16.135	NM_138357	MCU	mitochondrial calcium uniporter
chr16_-_4465876	16.089		CORO7	coronin 7
chr12_-_51717835	16.088		BIN2	bridging integrator 2
chr5_-_151066445	15.941		SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr22_+_38453478	15.935		PICK1	protein interacting with PRKCA 1
chr8_-_110657745	15.917	NM_001099751 NM_001099752	SYBU	syntabulin (syntaxin-interacting)
chr14_-_24780626	15.899
chr16_-_31084822	15.877	NM_001172668	ZNF668	zinc finger protein 668
chr16_+_8806825	15.725	NM_000663	ABAT	4-aminobutyrate aminotransferase
chr19_-_47975244	15.501	NM_015063	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr6_-_31514620	15.453	NM_001204078 NM_130463 NM_138282	ATP6V1G2	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr14_-_24780570	15.413	NM_014430	CIDEB	cell death-inducing DFFA-like effector b
chr12_-_51717941	15.402		BIN2	bridging integrator 2
chr1_-_59012379	15.346	NM_145243	OMA1	OMA1 zinc metallopeptidase homolog (S. cerevisiae)
chr14_-_107113943	15.335		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_-_124543598	15.315	NM_170601	SIAE	sialic acid acetylesterase
chr12_-_51717905	15.258	NM_016293	BIN2	bridging integrator 2
chr4_-_5828587	15.258		CRMP1	collapsin response mediator protein 1
chr17_+_18163836	15.165	NM_001144900 NM_139162	SMCR7	Smith-Magenis syndrome chromosome region, candidate 7
chr3_+_16926451	15.130	NM_001144382	PLCL2	phospholipase C-like 2
chr16_+_2198687	14.969		RAB26	RAB26, member RAS oncogene family
chr20_+_30102237	14.968	NM_030789 NM_178580 NM_178581 NM_178582	HM13	histocompatibility (minor) 13
chr9_-_130616592	14.946		ENG	endoglin
chr2_-_234475400	14.928		USP40	ubiquitin specific peptidase 40
chr20_+_30102261	14.910		HM13	histocompatibility (minor) 13
chr1_+_179712297	14.893	NM_173509	FAM163A	family with sequence similarity 163, member A
chr9_-_130616957	14.878		ENG	endoglin
chr12_+_54402795	14.870	NM_022658	HOXC8	homeobox C8
chr3_-_10067989	14.691		CIDECP	cell death-inducing DFFA-like effector c pseudogene
chr1_+_156589085	14.661	NM_021817	HAPLN2	hyaluronan and proteoglycan link protein 2
chr22_+_23229959	14.654	NM_001178126	IGLL5 IGLC1	immunoglobulin lambda-like polypeptide 5 immunoglobulin lambda constant 1 (Mcg marker)
chr11_-_33891258	14.612		LMO2	LIM domain only 2 (rhombotin-like 1)
chr15_-_77197743	14.583		SCAPER	S-phase cyclin A-associated protein in the ER
chr12_-_9360960	14.582	NM_002864	PZP	pregnancy-zone protein
chr1_+_16062808	14.530	NM_207348	SLC25A34	solute carrier family 25, member 34
chr14_-_24780641	14.502		CIDEB	cell death-inducing DFFA-like effector b
chr10_+_135480367	14.481	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chrX_+_21392396	14.454	NM_001168647 NM_001168648 NM_001168649 NM_014927	CNKSR2	connector enhancer of kinase suppressor of Ras 2
chr14_+_75536298	14.438	NM_001042430 NM_024643	FAM164C	family with sequence similarity 164, member C
chr17_+_74733468	14.398	NM_001242532 NM_001242533 NM_001242535 NM_001242536 NM_001242537 NM_024311	MFSD11	major facilitator superfamily domain containing 11
chr12_+_56623819	14.384	NM_173596	SLC39A5	solute carrier family 39 (metal ion transporter), member 5
chr21_+_47878764	14.351	NM_001146114 NM_001146115 NM_001146116 NM_015151 NM_206889 NM_206890 NM_206891	DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr1_+_205012427	14.350		CNTN2	contactin 2 (axonal)
chr11_+_313852	14.309	NM_003641	IFITM1	interferon induced transmembrane protein 1 (9-27)
chr8_-_27941387	14.268	NM_001010906	C8orf80	chromosome 8 open reading frame 80
chr19_-_51529869	14.230	NM_001136032	KLK11	kallikrein-related peptidase 11
chrX_+_128913897	14.128		SASH3	SAM and SH3 domain containing 3
chrX_-_43741593	14.123	NM_000898	MAOB	monoamine oxidase B
chr11_-_111782447	14.085	NM_001885	CRYAB	crystallin, alpha B
chr16_-_90038869	14.000		CENPBD1	CENPB DNA-binding domains containing 1
chr19_+_18942786	13.967		UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)
chrX_+_128913881	13.923	NM_018990	SASH3	SAM and SH3 domain containing 3
chr19_-_58629762	13.921	NM_001145542	ZSCAN18	zinc finger and SCAN domain containing 18
chr14_-_23834417	13.883		EFS	embryonal Fyn-associated substrate
chr12_+_50355278	13.776	NM_001651	AQP5	aquaporin 5
chr22_+_38035718	13.773		SH3BP1	SH3-domain binding protein 1
chr3_-_171177851	13.769	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr12_-_104443698	13.751		GLT8D2	glycosyltransferase 8 domain containing 2
chr9_+_126773851	13.661	NM_004789	LHX2	LIM homeobox 2
chr4_-_105412466	13.655	NM_025212	CXXC4	CXXC finger protein 4
chr22_-_29711474	13.633		RASL10A	RAS-like, family 10, member A
chr7_+_97910978	13.585	NM_001159491 NM_015379	BRI3	brain protein I3
chr12_+_53440809	13.489	NM_198316	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr6_+_132129195	13.476		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr16_-_325867	13.327	NM_003834 NM_183337	RGS11	regulator of G-protein signaling 11
chrX_-_50557019	13.324	NM_020717	SHROOM4	shroom family member 4
chr6_-_46922533	13.321	NM_015234	GPR116	G protein-coupled receptor 116
chr1_-_35325335	13.139	NM_001164825 NM_138428	C1orf212	chromosome 1 open reading frame 212
chr2_+_177053306	13.102	NM_024501	HOXD1	homeobox D1
chr14_+_21538339	13.090	NM_018071	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr11_-_117186918	13.076	NM_012104 NM_138971 NM_138972 NM_138973	BACE1	beta-site APP-cleaving enzyme 1
chr19_+_35773409	13.065	NM_021175	HAMP	hepcidin antimicrobial peptide
chr1_-_16563658	13.060	NM_030907	RSG1	REM2 and RAB-like small GTPase 1
chr11_+_57365577	13.058	NM_001032295	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr6_-_32551993	13.046		HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr3_-_39323183	12.993	NM_001171174	CX3CR1	chemokine (C-X3-C motif) receptor 1
chrX_+_54556726	12.992		GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.29	1.80e-28	GO:0065007	biological regulation
1.27	1.66e-22	GO:0050789	regulation of biological process
1.45	3.78e-22	GO:0023052	signaling
1.34	1.33e-20	GO:0032501	multicellular organismal process
1.16	2.15e-20	GO:0009987	cellular process
1.51	1.10e-19	GO:0048731	system development
1.47	4.20e-19	GO:0048856	anatomical structure development
1.44	4.41e-19	GO:0007275	multicellular organismal development
1.40	8.41e-18	GO:0032502	developmental process
1.26	8.70e-18	GO:0050794	regulation of cellular process
1.41	2.29e-15	GO:0007165	signal transduction
1.66	1.02e-14	GO:0007399	nervous system development
1.26	1.10e-14	GO:0050896	response to stimulus
1.51	1.00e-13	GO:0065008	regulation of biological quality
1.65	4.38e-12	GO:0051239	regulation of multicellular organismal process
1.31	1.01e-11	GO:0051716	cellular response to stimulus
1.47	5.67e-11	GO:0030154	cell differentiation
1.46	7.62e-11	GO:0048869	cellular developmental process
1.44	1.91e-10	GO:0042221	response to chemical stimulus
1.55	4.11e-10	GO:0009653	anatomical structure morphogenesis
1.49	8.29e-10	GO:0007166	cell surface receptor linked signaling pathway
1.73	1.25e-09	GO:0048699	generation of neurons
1.70	2.01e-09	GO:0022008	neurogenesis
1.77	3.53e-09	GO:0007267	cell-cell signaling
1.71	6.32e-09	GO:0040011	locomotion
1.45	1.25e-08	GO:0048513	organ development
1.65	6.01e-08	GO:0048468	cell development
1.62	6.13e-08	GO:0007154	cell communication
1.75	8.24e-08	GO:0030182	neuron differentiation
1.81	2.98e-07	GO:0048666	neuron development
1.86	3.32e-07	GO:0006935	chemotaxis
1.86	3.32e-07	GO:0042330	taxis
1.63	3.46e-07	GO:0009611	response to wounding
1.59	4.20e-07	GO:0009605	response to external stimulus
1.26	6.73e-07	GO:0019222	regulation of metabolic process
1.61	1.26e-06	GO:0050793	regulation of developmental process
1.35	1.98e-06	GO:0048519	negative regulation of biological process
1.89	2.00e-06	GO:0048667	cell morphogenesis involved in neuron differentiation
1.86	2.02e-06	GO:0050801	ion homeostasis
1.74	2.10e-06	GO:0048878	chemical homeostasis
1.88	2.38e-06	GO:0048812	neuron projection morphogenesis
1.34	2.44e-06	GO:0006950	response to stress
1.89	2.56e-06	GO:0006873	cellular ion homeostasis
1.83	2.80e-06	GO:0019226	transmission of nerve impulse
1.83	2.80e-06	GO:0031175	neuron projection development
1.83	2.80e-06	GO:0035637	multicellular organismal signaling
1.82	2.88e-06	GO:0032990	cell part morphogenesis
1.90	3.16e-06	GO:0007409	axonogenesis
1.82	3.67e-06	GO:0048858	cell projection morphogenesis
1.49	4.28e-06	GO:0002376	immune system process
1.71	5.86e-06	GO:0032989	cellular component morphogenesis
1.73	6.88e-06	GO:0000902	cell morphogenesis
1.85	7.84e-06	GO:0055082	cellular chemical homeostasis
1.38	1.06e-05	GO:0048583	regulation of response to stimulus
1.79	1.12e-05	GO:0000904	cell morphogenesis involved in differentiation
2.25	2.10e-05	GO:0072507	divalent inorganic cation homeostasis
1.96	2.12e-05	GO:0007411	axon guidance
1.61	3.33e-05	GO:2000026	regulation of multicellular organismal development
2.25	4.13e-05	GO:0055074	calcium ion homeostasis
2.25	4.13e-05	GO:0072503	cellular divalent inorganic cation homeostasis
1.25	4.59e-05	GO:0080090	regulation of primary metabolic process
1.52	4.69e-05	GO:0032879	regulation of localization
1.58	4.75e-05	GO:0006952	defense response
1.33	6.18e-05	GO:0048523	negative regulation of cellular process
1.68	7.21e-05	GO:0009887	organ morphogenesis
1.45	8.07e-05	GO:0010033	response to organic substance
1.79	9.52e-05	GO:0007268	synaptic transmission
1.65	9.81e-05	GO:0030030	cell projection organization
2.23	9.88e-05	GO:0006874	cellular calcium ion homeostasis
1.73	1.21e-04	GO:0001775	cell activation
2.08	1.63e-04	GO:0030168	platelet activation
1.80	1.71e-04	GO:0016477	cell migration
1.89	2.21e-04	GO:0055080	cation homeostasis
1.96	2.75e-04	GO:0055065	metal ion homeostasis
1.87	3.34e-04	GO:0044057	regulation of system process
2.48	3.47e-04	GO:0030802	regulation of cyclic nucleotide biosynthetic process
2.48	3.47e-04	GO:0030808	regulation of nucleotide biosynthetic process
1.23	3.84e-04	GO:0051179	localization
4.46	4.02e-04	GO:0048483	autonomic nervous system development
2.53	4.13e-04	GO:0030817	regulation of cAMP biosynthetic process
1.23	4.13e-04	GO:0031323	regulation of cellular metabolic process
2.74	4.81e-04	GO:0001505	regulation of neurotransmitter levels
1.72	4.94e-04	GO:0072358	cardiovascular system development
1.72	4.94e-04	GO:0072359	circulatory system development
1.66	5.16e-04	GO:0007186	G-protein coupled receptor protein signaling pathway
2.51	5.30e-04	GO:0030814	regulation of cAMP metabolic process
2.44	5.56e-04	GO:0001763	morphogenesis of a branching structure
2.57	6.20e-04	GO:0061138	morphogenesis of a branching epithelium
2.42	7.01e-04	GO:0030799	regulation of cyclic nucleotide metabolic process
1.65	7.01e-04	GO:0006928	cellular component movement
1.27	7.17e-04	GO:0009889	regulation of biosynthetic process
1.27	7.86e-04	GO:0031326	regulation of cellular biosynthetic process
3.06	8.13e-04	GO:0007269	neurotransmitter secretion
1.38	8.97e-04	GO:0065009	regulation of molecular function
1.94	9.03e-04	GO:0006875	cellular metal ion homeostasis
1.39	9.71e-04	GO:0035556	intracellular signal transduction
1.52	9.86e-04	GO:0048584	positive regulation of response to stimulus
1.57	1.00e-03	GO:0045595	regulation of cell differentiation
1.26	1.09e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64	1.10e-03	GO:0019725	cellular homeostasis
2.59	1.20e-03	GO:0045761	regulation of adenylate cyclase activity
2.50	1.32e-03	GO:0007204	elevation of cytosolic calcium ion concentration
1.87	1.40e-03	GO:0030003	cellular cation homeostasis
1.61	1.53e-03	GO:0042060	wound healing
1.69	1.73e-03	GO:0048870	cell motility
1.69	1.73e-03	GO:0051674	localization of cell
1.85	1.89e-03	GO:0006140	regulation of nucleotide metabolic process
2.54	2.00e-03	GO:0031279	regulation of cyclase activity
1.63	2.05e-03	GO:0051336	regulation of hydrolase activity
1.86	2.05e-03	GO:0019932	second-messenger-mediated signaling
1.34	2.14e-03	GO:0023051	regulation of signaling
3.39	2.30e-03	GO:0007422	peripheral nervous system development
1.83	2.50e-03	GO:0001501	skeletal system development
2.36	2.70e-03	GO:0051480	cytosolic calcium ion homeostasis
1.60	2.76e-03	GO:0050878	regulation of body fluid levels
1.54	2.86e-03	GO:0009790	embryo development
1.56	3.02e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.63	3.12e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.49	3.27e-03	GO:0051339	regulation of lyase activity
1.45	3.89e-03	GO:0042127	regulation of cell proliferation
1.25	3.94e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.25	4.26e-03	GO:0048518	positive regulation of biological process
1.64	4.52e-03	GO:0007599	hemostasis
1.81	4.61e-03	GO:0007610	behavior
1.46	5.10e-03	GO:0006811	ion transport
1.47	5.33e-03	GO:0009888	tissue development
5.36	5.63e-03	GO:0048484	enteric nervous system development
1.48	6.07e-03	GO:0055085	transmembrane transport
2.01	7.20e-03	GO:0003013	circulatory system process
2.01	7.20e-03	GO:0008015	blood circulation
1.65	8.99e-03	GO:0051094	positive regulation of developmental process
1.60	1.08e-02	GO:0007417	central nervous system development
1.61	1.15e-02	GO:0007596	blood coagulation
1.61	1.15e-02	GO:0050817	coagulation
1.21	1.43e-02	GO:0060255	regulation of macromolecule metabolic process
2.36	1.64e-02	GO:0006836	neurotransmitter transport
1.48	1.83e-02	GO:0006955	immune response
1.44	1.92e-02	GO:0042592	homeostatic process
1.64	1.95e-02	GO:0032583	regulation of gene-specific transcription
1.44	2.03e-02	GO:0009891	positive regulation of biosynthetic process
1.80	2.19e-02	GO:0051960	regulation of nervous system development
1.76	2.24e-02	GO:0034097	response to cytokine stimulus
1.47	2.29e-02	GO:0007155	cell adhesion
1.47	2.29e-02	GO:0022610	biological adhesion
1.37	2.48e-02	GO:0050790	regulation of catalytic activity
1.81	2.75e-02	GO:0001568	blood vessel development
1.84	2.97e-02	GO:0051241	negative regulation of multicellular organismal process
2.26	3.02e-02	GO:0060193	positive regulation of lipase activity
1.63	3.11e-02	GO:0040008	regulation of growth
1.77	3.19e-02	GO:0001944	vasculature development
1.44	3.33e-02	GO:0031328	positive regulation of cellular biosynthetic process
3.73	3.95e-02	GO:0021545	cranial nerve development
3.35	4.26e-02	GO:0021675	nerve development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.64	5.16e-25	GO:0044459	plasma membrane part
1.78	1.05e-18	GO:0005887	integral to plasma membrane
1.76	1.67e-18	GO:0031226	intrinsic to plasma membrane
1.33	8.46e-15	GO:0005886	plasma membrane
1.33	1.17e-14	GO:0071944	cell periphery
1.70	1.32e-06	GO:0030054	cell junction
1.14	8.05e-06	GO:0016020	membrane
1.78	2.83e-05	GO:0045202	synapse
1.53	3.09e-05	GO:0005626	insoluble fraction
1.47	3.14e-05	GO:0044421	extracellular region part
1.43	1.50e-04	GO:0000267	cell fraction
1.81	5.92e-04	GO:0044456	synapse part
1.47	7.50e-04	GO:0005624	membrane fraction
1.47	1.22e-03	GO:0005615	extracellular space
1.13	1.52e-03	GO:0044425	membrane part
1.66	1.92e-03	GO:0043005	neuron projection
1.67	2.55e-03	GO:0031012	extracellular matrix
1.71	5.04e-03	GO:0005578	proteinaceous extracellular matrix
1.26	5.87e-03	GO:0005576	extracellular region
1.63	7.21e-03	GO:0009986	cell surface
2.01	1.10e-02	GO:0045211	postsynaptic membrane
1.82	1.63e-02	GO:0034702	ion channel complex
1.39	1.70e-02	GO:0042995	cell projection

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.65	6.53e-10	GO:0001071	nucleic acid binding transcription factor activity
1.65	6.53e-10	GO:0003700	sequence-specific DNA binding transcription factor activity
1.76	6.92e-09	GO:0043565	sequence-specific DNA binding
1.17	3.40e-08	GO:0005515	protein binding
1.46	2.83e-04	GO:0022857	transmembrane transporter activity
1.71	4.46e-04	GO:0022803	passive transmembrane transporter activity
1.69	7.81e-04	GO:0015267	channel activity
1.42	1.57e-03	GO:0005102	receptor binding
1.07	2.05e-03	GO:0005488	binding
1.66	2.97e-03	GO:0022838	substrate-specific channel activity
1.27	3.39e-03	GO:0004871	signal transducer activity
1.27	3.39e-03	GO:0060089	molecular transducer activity
1.36	4.57e-03	GO:0005215	transporter activity
1.39	5.12e-03	GO:0030528	transcription regulator activity
1.74	5.54e-03	GO:0022836	gated channel activity
1.65	5.72e-03	GO:0005216	ion channel activity
2.08	7.24e-03	GO:0005539	glycosaminoglycan binding
1.41	8.57e-03	GO:0022891	substrate-specific transmembrane transporter activity
3.21	1.01e-02	GO:0003823	antigen binding
1.45	1.06e-02	GO:0015075	ion transmembrane transporter activity
2.23	1.42e-02	GO:0019955	cytokine binding
2.07	1.80e-02	GO:0004713	protein tyrosine kinase activity
1.56	1.84e-02	GO:0030695	GTPase regulator activity
1.97	2.07e-02	GO:0001871	pattern binding
1.97	2.07e-02	GO:0030247	polysaccharide binding
1.36	2.66e-02	GO:0022892	substrate-specific transporter activity
1.36	4.48e-02	GO:0030234	enzyme regulator activity