Motif ID: SNAI1..3.p2

Z-value: 2.747


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SNAI2chr8_-_49833823-0.497.4e-15Click!
SNAI1chr20_+_485995110.488.8e-14Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_38755238 78.185 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755422 75.620 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755097 71.974 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr17_-_7165788 53.983 CLDN7
claudin 7
chr19_-_12886263 45.102 HOOK2
hook homolog 2 (Drosophila)
chr15_-_76030958 44.525 DNM1P35
DNM1 pseudogene 35
chr17_-_7166263 41.292 NM_001185023
NM_001307
 CLDN7

claudin 7

chr11_-_68518910 39.760 MTL5
metallothionein-like 5, testis-specific (tesmin)
chr9_-_97401588 35.812 FBP1
fructose-1,6-bisphosphatase 1
chr14_-_61748510 34.501 NM_001017970
 TMEM30B
transmembrane protein 30B
chr6_-_136871542 33.739 MAP7
microtubule-associated protein 7
chr9_-_97401746 33.062 FBP1
fructose-1,6-bisphosphatase 1
chr1_+_60280462 31.429 NM_015888
 HOOK1
hook homolog 1 (Drosophila)
chr14_-_61747956 31.139 TMEM30B
transmembrane protein 30B
chr1_+_1981902 30.603 NM_002744
 PRKCZ
protein kinase C, zeta
chr14_+_75745480 29.271 NM_005252
 FOS
FBJ murine osteosarcoma viral oncogene homolog
chr22_+_22697538 28.768


chr19_-_12886421 28.672 NM_001100176
NM_013312
 HOOK2

hook homolog 2 (Drosophila)

chr16_+_68771214 28.503 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr16_+_68771192 27.885 NM_004360
 CDH1
cadherin 1, type 1, E-cadherin (epithelial)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 141 entries
enrichment   p-value GO term description
2.40 3.67e-02 GO:0006941 striated muscle contraction
1.89 6.80e-06 GO:0006936 muscle contraction
1.89 2.41e-03 GO:0007565 female pregnancy
1.85 6.03e-06 GO:0003012 muscle system process
1.82 2.91e-03 GO:0002521 leukocyte differentiation
1.76 5.82e-05 GO:0003013 circulatory system process
1.76 5.82e-05 GO:0008015 blood circulation
1.75 7.61e-03 GO:0043406 positive regulation of MAP kinase activity
1.74 1.37e-03 GO:0071902 positive regulation of protein serine/threonine kinase activity
1.74 1.35e-02 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger
1.73 7.62e-03 GO:0002237 response to molecule of bacterial origin
1.72 3.19e-02 GO:0032496 response to lipopolysaccharide
1.72 4.24e-02 GO:0001503 ossification
1.67 3.91e-02 GO:0019935 cyclic-nucleotide-mediated signaling
1.61 2.82e-02 GO:0048732 gland development
1.60 1.71e-14 GO:0007267 cell-cell signaling
1.59 8.79e-04 GO:0048534 hemopoietic or lymphoid organ development
1.59 6.97e-03 GO:0008202 steroid metabolic process
1.58 8.69e-03 GO:0030168 platelet activation
1.58 3.97e-02 GO:0043405 regulation of MAP kinase activity

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
1.78 5.64e-04 GO:0043235 receptor complex
1.75 4.52e-07 GO:0016323 basolateral plasma membrane
1.63 3.39e-03 GO:0016324 apical plasma membrane
1.59 4.19e-27 GO:0005887 integral to plasma membrane
1.58 7.83e-27 GO:0031226 intrinsic to plasma membrane
1.51 1.88e-02 GO:0045177 apical part of cell
1.50 4.49e-02 GO:0005911 cell-cell junction
1.49 4.32e-35 GO:0044459 plasma membrane part
1.45 4.42e-04 GO:0045202 synapse
1.45 1.87e-02 GO:0012506 vesicle membrane
1.44 3.87e-02 GO:0030659 cytoplasmic vesicle membrane
1.43 1.66e-08 GO:0005615 extracellular space
1.43 2.44e-03 GO:0009986 cell surface
1.43 1.18e-02 GO:0044433 cytoplasmic vesicle part
1.42 6.88e-06 GO:0030054 cell junction
1.40 9.89e-10 GO:0044421 extracellular region part
1.40 1.54e-07 GO:0005626 insoluble fraction
1.40 1.05e-02 GO:0031012 extracellular matrix
1.37 4.11e-06 GO:0005624 membrane fraction
1.36 3.38e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
2.60 4.45e-03 GO:0015296 anion:cation symporter activity
2.46 2.96e-04 GO:0001948 glycoprotein binding
1.99 9.33e-03 GO:0005200 structural constituent of cytoskeleton
1.87 4.00e-04 GO:0030674 protein binding, bridging
1.84 3.20e-04 GO:0060090 binding, bridging
1.83 3.47e-02 GO:0015294 solute:cation symporter activity
1.78 1.17e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.74 6.66e-03 GO:0015276 ligand-gated ion channel activity
1.74 6.66e-03 GO:0022834 ligand-gated channel activity
1.64 4.06e-03 GO:0001664 G-protein-coupled receptor binding
1.51 3.77e-03 GO:0005261 cation channel activity
1.47 8.83e-03 GO:0005083 small GTPase regulator activity
1.46 8.02e-03 GO:0022836 gated channel activity
1.44 1.26e-05 GO:0008324 cation transmembrane transporter activity
1.42 7.65e-04 GO:0030695 GTPase regulator activity
1.41 3.88e-02 GO:0003779 actin binding
1.40 1.69e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.40 6.05e-03 GO:0022803 passive transmembrane transporter activity
1.40 8.64e-03 GO:0015267 channel activity
1.39 5.38e-09 GO:0005102 receptor binding