Motif ID: SOX17.p2

Z-value: 1.737


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX17chr8_+_55370494-0.195.2e-03Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_153643456 76.789 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_153643474 74.145 NM_004515
 ILF2
interleukin enhancer binding factor 2, 45kDa
chr7_-_44887620 73.359 H2AFV
H2A histone family, member V
chr1_-_153643433 72.914 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_153643428 71.116 ILF2
interleukin enhancer binding factor 2, 45kDa
chr7_-_44887567 71.035 H2AFV
H2A histone family, member V
chr1_-_153643417 69.686 ILF2
interleukin enhancer binding factor 2, 45kDa
chr5_+_177631533 62.366 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr5_+_177631496 60.472 NM_004499
NM_031266
 HNRNPAB

heterogeneous nuclear ribonucleoprotein A/B

chr17_-_73150493 54.893 HN1
hematological and neurological expressed 1
chr5_+_177631534 52.701 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr16_+_56817367 51.279 NM_001242796
 NUP93
nucleoporin 93kDa
chr5_+_68462948 47.491 CCNB1
cyclin B1
chr5_+_68462985 42.820 CCNB1
cyclin B1
chr13_-_31040035 41.519 NM_002128
 HMGB1
high mobility group box 1
chr2_-_61765394 39.813 NM_003400
 XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_+_43824598 39.506 NM_001255
 CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr13_-_31039966 37.700 HMGB1
high mobility group box 1
chr5_+_68462836 33.728 NM_031966
 CCNB1
cyclin B1
chr1_+_110882063 30.411 RBM15
RNA binding motif protein 15

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 153 entries
enrichment   p-value GO term description
3.39 2.52e-03 GO:0006839 mitochondrial transport
3.10 1.51e-04 GO:0050657 nucleic acid transport
3.10 1.51e-04 GO:0050658 RNA transport
3.10 1.51e-04 GO:0051236 establishment of RNA localization
3.02 1.27e-03 GO:0051028 mRNA transport
3.00 3.22e-04 GO:0006403 RNA localization
2.93 3.92e-03 GO:0000086 G2/M transition of mitotic cell cycle
2.90 4.68e-03 GO:0000084 S phase of mitotic cell cycle
2.86 9.90e-03 GO:0090068 positive regulation of cell cycle process
2.85 6.61e-03 GO:0051320 S phase
2.84 4.71e-02 GO:0006334 nucleosome assembly
2.83 1.17e-02 GO:0065004 protein-DNA complex assembly
2.82 4.93e-04 GO:0000082 G1/S transition of mitotic cell cycle
2.79 6.81e-10 GO:0051329 interphase of mitotic cell cycle
2.78 4.86e-06 GO:0000375 RNA splicing, via transesterification reactions
2.74 1.53e-09 GO:0051325 interphase
2.74 5.66e-03 GO:0007093 mitotic cell cycle checkpoint
2.71 2.43e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.71 2.43e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
2.68 3.09e-02 GO:0071824 protein-DNA complex subunit organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 43 entries
enrichment   p-value GO term description
7.26 7.63e-05 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
4.79 3.28e-03 GO:0000932 cytoplasmic mRNA processing body
3.56 3.74e-02 GO:0017053 transcriptional repressor complex
3.50 6.36e-03 GO:0016605 PML body
3.41 1.37e-03 GO:0005643 nuclear pore
2.99 5.83e-03 GO:0046930 pore complex
2.68 4.13e-07 GO:0016604 nuclear body
2.64 2.42e-02 GO:0005788 endoplasmic reticulum lumen
2.61 4.24e-02 GO:0032993 protein-DNA complex
2.27 3.90e-04 GO:0000785 chromatin
2.10 6.77e-22 GO:0005654 nucleoplasm
2.06 4.71e-07 GO:0030529 ribonucleoprotein complex
2.05 2.89e-02 GO:0000228 nuclear chromosome
2.04 4.62e-10 GO:0044451 nucleoplasm part
2.00 2.38e-02 GO:0005635 nuclear envelope
1.99 2.03e-05 GO:0044427 chromosomal part
1.97 2.19e-06 GO:0005694 chromosome
1.96 1.37e-24 GO:0031981 nuclear lumen
1.92 8.11e-28 GO:0044428 nuclear part
1.87 4.02e-27 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.88 3.94e-02 GO:0003729 mRNA binding
2.43 9.31e-03 GO:0003714 transcription corepressor activity
2.13 2.52e-04 GO:0016564 transcription repressor activity
2.08 1.75e-12 GO:0003723 RNA binding
2.06 2.10e-03 GO:0008134 transcription factor binding
2.01 2.91e-04 GO:0003712 transcription cofactor activity
2.00 3.18e-04 GO:0000988 protein binding transcription factor activity
2.00 3.18e-04 GO:0000989 transcription factor binding transcription factor activity
1.67 6.63e-06 GO:0030528 transcription regulator activity
1.55 2.70e-02 GO:0019899 enzyme binding
1.49 1.05e-45 GO:0005515 protein binding
1.49 1.46e-02 GO:0001071 nucleic acid binding transcription factor activity
1.49 1.46e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.48 3.79e-13 GO:0003676 nucleic acid binding
1.40 1.67e-05 GO:0003677 DNA binding
1.40 3.10e-05 GO:0000166 nucleotide binding
1.21 2.13e-27 GO:0005488 binding