Motif ID: SOX5.p2

Z-value: 1.103


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX5chr12_-_24103953-0.063.8e-01Click!


Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_198608244 34.572 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_198608136 29.166 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_198608216 24.609 PTPRC
protein tyrosine phosphatase, receptor type, C
chrX_+_123234462 23.361 STAG2
stromal antigen 2
chr9_-_86584079 20.529 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr16_+_56817367 17.165 NM_001242796
 NUP93
nucleoporin 93kDa
chr12_+_69742130 16.381 NM_000239
 LYZ
lysozyme
chr4_-_83347222 15.759 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr17_+_65822242 15.576 BPTF
bromodomain PHD finger transcription factor
chr10_+_11206928 15.172 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr17_+_65822206 14.893 BPTF
bromodomain PHD finger transcription factor
chr12_+_69742140 14.095 LYZ
lysozyme
chr2_+_143886898 12.800 NM_018460
 ARHGAP15
Rho GTPase activating protein 15
chr7_-_26232148 12.687 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr16_+_56815703 12.261 NM_001242795
 NUP93
nucleoporin 93kDa
chr2_+_143886969 12.087 ARHGAP15
Rho GTPase activating protein 15
chr2_-_225370687 12.063 CUL3
cullin 3
chrY_+_15016018 11.132 NM_001122665
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr10_+_11207053 9.640 CELF2
CUGBP, Elav-like family member 2
chr1_+_174844655 9.572 NM_001035230
 RABGAP1L
RAB GTPase activating protein 1-like

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
6.51 2.91e-02 GO:0050853 B cell receptor signaling pathway
2.39 2.52e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.39 2.52e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.32 4.21e-02 GO:0000375 RNA splicing, via transesterification reactions
2.26 1.52e-04 GO:0016568 chromatin modification
2.18 6.04e-03 GO:0008380 RNA splicing
2.03 6.11e-03 GO:0006397 mRNA processing
1.98 1.85e-03 GO:0006325 chromatin organization
1.94 1.34e-04 GO:0051276 chromosome organization
1.83 1.45e-03 GO:0006396 RNA processing
1.79 3.70e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.78 8.15e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.74 2.51e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.73 1.86e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.73 3.29e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.73 4.06e-02 GO:0010629 negative regulation of gene expression
1.70 7.89e-03 GO:0006955 immune response
1.69 3.80e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.65 1.28e-08 GO:0010467 gene expression
1.64 8.97e-05 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
6.01 2.86e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
4.80 2.13e-02 GO:0005720 nuclear heterochromatin
3.40 1.33e-03 GO:0000790 nuclear chromatin
2.89 2.27e-02 GO:0016585 chromatin remodeling complex
2.42 2.29e-04 GO:0000785 chromatin
2.26 4.18e-03 GO:0016604 nuclear body
1.99 3.55e-05 GO:0030529 ribonucleoprotein complex
1.78 1.32e-04 GO:0044451 nucleoplasm part
1.75 6.93e-09 GO:0005654 nucleoplasm
1.73 4.32e-02 GO:0044427 chromosomal part
1.71 1.33e-02 GO:0005694 chromosome
1.66 3.74e-10 GO:0031981 nuclear lumen
1.65 5.44e-12 GO:0044428 nuclear part
1.47 8.94e-07 GO:0043233 organelle lumen
1.47 1.35e-06 GO:0070013 intracellular organelle lumen
1.46 1.25e-06 GO:0031974 membrane-enclosed lumen
1.31 4.71e-10 GO:0005634 nucleus
1.24 1.25e-02 GO:0032991 macromolecular complex
1.12 7.11e-03 GO:0043227 membrane-bounded organelle
1.12 7.98e-03 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
5.03 4.07e-04 GO:0003823 antigen binding
2.56 9.94e-03 GO:0003714 transcription corepressor activity
1.89 5.10e-07 GO:0003723 RNA binding
1.45 3.96e-10 GO:0003676 nucleic acid binding
1.41 7.71e-05 GO:0003677 DNA binding
1.26 2.85e-11 GO:0005515 protein binding
1.11 1.22e-06 GO:0005488 binding