Motif ID: SPI1.p2

Z-value: 3.385


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_474000960.537.5e-17Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153518265 59.426 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr1_+_26644458 51.606 CD52
CD52 molecule
chr11_-_46142955 51.341 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr16_-_88717395 47.078 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr21_-_46340821 44.407 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr22_+_37257004 44.255 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr6_-_31704272 43.958 CLIC1
chloride intracellular channel 1
chr15_+_75074714 42.427 CSK
c-src tyrosine kinase
chrX_+_48542159 40.855 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr6_-_32160289 40.716 GPSM3
G-protein signaling modulator 3
chr19_+_35645614 40.233 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr1_-_31230673 39.446 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr5_+_118691692 39.015 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chrX_-_47489243 38.903 NM_001145252
CFP
complement factor properdin
chr19_+_35645640 37.902 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr6_-_31704070 37.884 CLIC1
chloride intracellular channel 1
chr10_-_88281486 37.827 WAPAL
wings apart-like homolog (Drosophila)
chrX_-_47489703 36.895 NM_002621
CFP
complement factor properdin
chr15_+_75074417 35.900 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr19_+_49838700 35.649 CD37
CD37 molecule
chr10_-_27149892 35.422 ABI1
abl-interactor 1
chr10_-_27149791 35.201 ABI1
abl-interactor 1
chr6_-_31704093 35.155 CLIC1
chloride intracellular channel 1
chr19_-_10450262 35.019 NM_002162
ICAM3
intercellular adhesion molecule 3
chr4_-_185395616 33.114 NM_002199
IRF2
interferon regulatory factor 2
chr20_+_43514340 31.658 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr6_-_32812711 31.023 NM_004159
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr6_-_32812409 30.909 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr9_+_131451823 30.908 SET
SET nuclear oncogene
chr6_-_31704287 30.872 CLIC1
chloride intracellular channel 1
chr1_-_153363544 30.806 NM_002964
S100A8
S100 calcium binding protein A8
chr1_-_111743297 30.439 DENND2D
DENN/MADD domain containing 2D
chrX_-_118827060 30.334 SEPT6
septin 6
chr6_-_31704318 30.119 NM_001288
CLIC1
chloride intracellular channel 1
chr2_+_109237679 29.285 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr20_+_3776905 29.245 CDC25B
cell division cycle 25 homolog B (S. pombe)
chr21_-_46340874 28.486 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_31550065 28.337 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr7_-_86848818 28.203 NM_024315
C7orf23
chromosome 7 open reading frame 23
chr8_+_22437983 28.133 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr21_-_46340776 27.601 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr12_+_25205180 27.537 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr14_-_23288912 27.396 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_-_58343308 27.265 NM_004811
LPXN
leupaxin
chr12_-_51717835 27.264 BIN2
bridging integrator 2
chr19_-_8642297 27.202 MYO1F
myosin IF
chr12_-_51717905 27.045 NM_016293
BIN2
bridging integrator 2
chr12_-_51717941 26.939 BIN2
bridging integrator 2
chr14_-_35344450 26.802 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr2_+_219082119 26.759 NM_005731
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_32235805 26.651 MEMO1
mediator of cell motility 1
chr12_+_7060554 26.633 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_32812189 26.576 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr11_-_102323353 26.205 NM_052932
TMEM123
transmembrane protein 123
chr1_-_150241409 26.202 NM_001077628
NM_001243771
NM_001243772
NM_016022
APH1A



anterior pharynx defective 1 homolog A (C. elegans)



chr14_-_35344080 26.086 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr17_-_29641094 26.030 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_4851688 25.996 PFN1
profilin 1
chr19_+_49838673 25.605 NM_001040031
NM_001774
CD37

CD37 molecule

chr1_+_111415791 25.352 CD53
CD53 molecule
chr16_+_30194730 25.326 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr6_-_32811773 25.166 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr2_+_85198431 25.047 KCMF1
potassium channel modulatory factor 1
chr15_-_65282093 24.961 SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr2_+_219081864 24.737 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr17_+_65822206 24.704 BPTF
bromodomain PHD finger transcription factor
chr2_-_61697899 24.350 USP34
ubiquitin specific peptidase 34
chr7_+_141438122 24.296 NM_003143
SSBP1
single-stranded DNA binding protein 1
chr19_+_49838646 24.065 CD37
CD37 molecule
chr2_+_219081898 23.549 ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_61765367 23.546 XPO1
exportin 1 (CRM1 homolog, yeast)
chr10_-_88281515 23.497 NM_015045
WAPAL
wings apart-like homolog (Drosophila)
chrX_-_15872905 23.471


chr11_+_128563772 23.451 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chr1_+_111415721 23.414 NM_000560
CD53
CD53 molecule
chr2_+_143886969 23.360 ARHGAP15
Rho GTPase activating protein 15
chr2_-_174828775 23.042 NM_001017371
SP3
Sp3 transcription factor
chr3_-_195163575 23.002 NM_012287
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr6_+_31553955 22.969 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr2_-_153573858 22.825 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr19_+_48828820 22.817 EMP3
epithelial membrane protein 3
chr19_+_35646006 22.808 FXYD5
FXYD domain containing ion transport regulator 5
chr17_-_29641087 22.633 EVI2B
ecotropic viral integration site 2B
chr2_-_136873740 22.599 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr17_+_43299277 22.486 NM_005892
FMNL1
formin-like 1
chr14_-_24616429 22.475 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr1_-_150552127 22.185 NM_001197320
NM_021960
NM_182763
MCL1


myeloid cell leukemia sequence 1 (BCL2-related)


chr12_+_69004684 22.164 RAP1B
RAP1B, member of RAS oncogene family
chr3_-_121379757 22.012 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_+_25205488 22.005 LRMP
lymphoid-restricted membrane protein
chr14_-_23285011 22.001 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_-_56084611 21.937 SRSF1
serine/arginine-rich splicing factor 1
chr17_-_62657997 21.823 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr1_-_31230594 21.804 LAPTM5
lysosomal protein transmembrane 5
chr12_+_69004614 21.717 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
RAP1B





RAP1B, member of RAS oncogene family





chr1_-_184943673 21.491 NM_052966
FAM129A
family with sequence similarity 129, member A
chr3_+_107241782 21.406 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr14_-_99737554 21.205 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr19_-_9546154 21.034 NM_006631
NM_198058
ZNF266

zinc finger protein 266

chr2_-_32235722 21.021 MEMO1
mediator of cell motility 1
chr12_+_69004710 20.939 RAP1B
RAP1B, member of RAS oncogene family
chr1_-_151032082 20.923 NM_001038707
NM_020239
CDC42SE1

CDC42 small effector 1

chr1_+_26644380 20.902 NM_001803
CD52
CD52 molecule
chr13_+_31287614 20.857 NM_001204406
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr1_-_151032036 20.791 CDC42SE1
CDC42 small effector 1
chr3_-_125094003 20.770 NM_021964
ZNF148
zinc finger protein 148
chr6_-_33282006 20.700 NM_003190
NM_172208
NM_172209
TAPBP


TAP binding protein (tapasin)


chr4_-_174254730 20.680 NM_001130689
HMGB2
high mobility group box 2
chr6_-_31704281 20.630 CLIC1
chloride intracellular channel 1
chr9_+_131451519 20.606 SET
SET nuclear oncogene
chr7_-_99698278 20.486 NM_182776
MCM7
minichromosome maintenance complex component 7
chr10_-_27149989 20.384 NM_001012750
NM_001012751
NM_001012752
NM_001178116
NM_001178119
NM_001178120
NM_001178121
NM_001178122
NM_001178123
NM_001178124
NM_001178125
NM_005470
ABI1











abl-interactor 1











chr8_-_101733735 20.202 PABPC1
poly(A) binding protein, cytoplasmic 1
chr19_+_49838734 19.994 CD37
CD37 molecule
chr12_+_7055753 19.674 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_+_41748488 19.513 NM_013397
PRICKLE4
prickle homolog 4 (Drosophila)
chr14_+_96968768 19.412 PAPOLA
poly(A) polymerase alpha
chr2_-_32235603 19.400 NM_001137602
NM_015955
MEMO1

mediator of cell motility 1

chr6_+_42896859 19.324 NM_006586
CNPY3
canopy 3 homolog (zebrafish)
chrX_-_15872882 19.243 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr14_+_21249209 19.190 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr3_-_121379701 19.090 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr17_+_45727274 19.058 NM_002265
KPNB1
karyopherin (importin) beta 1
chr3_-_156878481 19.010 NM_020307
CCNL1
cyclin L1
chr19_+_49376488 18.979 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr6_-_79787939 18.923 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr12_-_49960221 18.750 NM_001012300
MCRS1
microspherule protein 1
chr12_-_110888079 18.716 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr19_+_48828627 18.678 NM_001425
EMP3
epithelial membrane protein 3
chr12_-_108954952 18.651 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr6_-_31704304 18.651 CLIC1
chloride intracellular channel 1
chr2_-_61765394 18.636 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr17_+_65822242 18.612 BPTF
bromodomain PHD finger transcription factor
chr6_+_26368405 18.600 NM_001197246
BTN3A2
butyrophilin, subfamily 3, member A2
chr19_-_39108534 18.587 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr8_+_56792399 18.573 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_-_31324564 18.548 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr12_-_110888134 18.510 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr6_-_75994496 18.486 TMEM30A
transmembrane protein 30A
chr19_-_8642309 18.378 NM_012335
MYO1F
myosin IF
chr16_-_89043215 18.334 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr14_-_35344490 18.312 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr12_-_108954942 18.279 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr14_-_99737821 18.247 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr12_-_53601051 18.245 ITGB7
integrin, beta 7
chr2_+_68592317 18.155 NM_002664
PLEK
pleckstrin
chr14_-_35344526 18.031 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr1_-_147931877 17.925 FLJ39739
uncharacterized FLJ39739
chr12_-_92539614 17.917 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_+_56792345 17.894 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr1_-_224622000 17.856 NM_001115113
NM_025160
WDR26

WD repeat domain 26

chr7_+_74188308 17.840 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chrX_+_123095555 17.742 NM_001042750
NM_001042751
NM_006603
STAG2


stromal antigen 2


chr12_-_53600999 17.645 NM_000889
ITGB7
integrin, beta 7
chr8_+_126442557 17.622 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr12_-_49319211 17.603 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr1_+_113161723 17.598 CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr3_+_180630431 17.573 FXR1
fragile X mental retardation, autosomal homolog 1
chr12_+_7060433 17.571 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr22_-_50964856 17.533 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr1_+_155178489 17.344 NM_002455
NM_198883
MTX1

metaxin 1

chr6_-_75994631 17.299 NM_001143958
NM_018247
TMEM30A

transmembrane protein 30A

chr22_-_37882214 17.290 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr12_+_54891539 17.202 NCKAP1L
NCK-associated protein 1-like
chr8_+_56792392 17.142 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chrX_-_15872921 17.060 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_-_61765345 17.034 XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_-_31479120 16.980 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr3_+_38179968 16.944 NM_001172566
NM_001172567
NM_001172568
NM_001172569
NM_002468
MYD88




myeloid differentiation primary response gene (88)




chr11_-_2018885 16.883 H19
RPS12
H19, imprinted maternally expressed transcript (non-protein coding)
ribosomal protein S12
chr3_-_16555128 16.844 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr12_+_54891522 16.762 NCKAP1L
NCK-associated protein 1-like
chr20_+_47835964 16.639 DDX27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chrX_+_47004693 16.629 RBM10
RNA binding motif protein 10
chr12_+_54891491 16.611 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr1_-_150552005 16.518 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr12_-_57505176 16.494 NM_001178078
NM_001178080
NM_001178081
NM_003153
STAT6



signal transducer and activator of transcription 6, interleukin-4 induced



chr1_+_112162397 16.491 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr1_-_155948934 16.481 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr18_+_56338818 16.445 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr17_-_34417386 16.428 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr17_+_37026351 16.400 LASP1
LIM and SH3 protein 1
chr6_-_32157511 16.334 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr11_-_3862183 16.236 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr2_+_219081914 16.150 ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr6_-_32160637 15.974 GPSM3
G-protein signaling modulator 3
chr2_+_143886898 15.884 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr1_-_183559669 15.839 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr6_-_75994477 15.803 TMEM30A
transmembrane protein 30A
chr1_-_183560010 15.752 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr12_-_56652118 15.731 NM_173595
ANKRD52
ankyrin repeat domain 52
chr14_-_23284617 15.666 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_120687956 15.651 NM_025157
PXN
paxillin
chr6_+_155054549 15.647 SCAF8
SR-related CTD-associated factor 8
chr19_-_8642337 15.571 MYO1F
myosin IF
chr10_+_28822387 15.542 NM_016628
NM_100486
WAC

WW domain containing adaptor with coiled-coil

chr20_+_43514350 15.541 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr22_+_37309618 15.492 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr17_+_1733263 15.458 NM_002945
RPA1
replication protein A1, 70kDa
chr11_-_67120943 15.430 NM_021173
POLD4
polymerase (DNA-directed), delta 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.20 8.12e-63 GO:0009987 cellular process
1.47 3.34e-60 GO:0044260 cellular macromolecule metabolic process
1.35 6.60e-55 GO:0044237 cellular metabolic process
1.41 1.39e-54 GO:0043170 macromolecule metabolic process
1.28 2.60e-44 GO:0008152 metabolic process
1.31 2.82e-43 GO:0044238 primary metabolic process
1.52 3.56e-39 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58 1.69e-37 GO:0090304 nucleic acid metabolic process
1.25 1.59e-35 GO:0050789 regulation of biological process
1.25 2.30e-33 GO:0050794 regulation of cellular process
1.22 8.18e-33 GO:0065007 biological regulation
1.62 3.95e-32 GO:0016070 RNA metabolic process
1.43 5.49e-32 GO:0034641 cellular nitrogen compound metabolic process
1.42 2.55e-31 GO:0006807 nitrogen compound metabolic process
1.56 1.81e-28 GO:0010467 gene expression
1.46 1.79e-27 GO:0044267 cellular protein metabolic process
1.67 1.07e-25 GO:0002376 immune system process
1.32 8.68e-24 GO:0051716 cellular response to stimulus
1.39 3.42e-21 GO:0048518 positive regulation of biological process
1.41 8.14e-21 GO:0048522 positive regulation of cellular process
1.36 1.10e-20 GO:0019538 protein metabolic process
1.41 2.45e-20 GO:0006950 response to stress
1.33 2.85e-20 GO:0071840 cellular component organization or biogenesis
1.33 3.80e-20 GO:0016043 cellular component organization
1.94 6.89e-20 GO:0016071 mRNA metabolic process
1.33 1.02e-19 GO:0060255 regulation of macromolecule metabolic process
1.30 2.65e-19 GO:0019222 regulation of metabolic process
1.49 7.48e-19 GO:0009059 macromolecule biosynthetic process
1.31 1.25e-18 GO:0031323 regulation of cellular metabolic process
1.48 3.16e-18 GO:0034645 cellular macromolecule biosynthetic process
1.39 9.01e-18 GO:0048519 negative regulation of biological process
1.41 3.15e-17 GO:0048523 negative regulation of cellular process
2.16 1.07e-16 GO:0008380 RNA splicing
1.30 1.35e-16 GO:0080090 regulation of primary metabolic process
1.59 9.65e-16 GO:0032268 regulation of cellular protein metabolic process
1.30 1.48e-15 GO:0007165 signal transduction
1.69 3.04e-15 GO:0006955 immune response
1.74 9.49e-15 GO:0006396 RNA processing
1.35 1.47e-14 GO:0044249 cellular biosynthetic process
1.55 1.68e-14 GO:0051246 regulation of protein metabolic process
1.74 1.79e-14 GO:0051726 regulation of cell cycle
1.56 4.26e-14 GO:0042981 regulation of apoptosis
1.56 4.55e-14 GO:0043067 regulation of programmed cell death
1.40 5.58e-14 GO:0006464 protein modification process
1.97 6.56e-14 GO:0044419 interspecies interaction between organisms
1.39 8.75e-14 GO:0043412 macromolecule modification
1.32 9.79e-14 GO:0071841 cellular component organization or biogenesis at cellular level
1.62 1.51e-13 GO:0033554 cellular response to stress
1.32 1.93e-13 GO:0071842 cellular component organization at cellular level
2.29 1.95e-13 GO:0000375 RNA splicing, via transesterification reactions
2.30 2.95e-13 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.30 2.95e-13 GO:0000398 nuclear mRNA splicing, via spliceosome
1.53 5.44e-13 GO:0010941 regulation of cell death
1.18 8.02e-13 GO:0050896 response to stimulus
1.32 1.30e-12 GO:0009058 biosynthetic process
1.61 1.33e-12 GO:0031399 regulation of protein modification process
1.76 1.33e-12 GO:0044265 cellular macromolecule catabolic process
1.70 2.11e-12 GO:0009057 macromolecule catabolic process
1.89 2.83e-12 GO:0006397 mRNA processing
1.54 3.81e-12 GO:0032774 RNA biosynthetic process
1.40 1.16e-11 GO:0006996 organelle organization
1.48 1.30e-11 GO:0031325 positive regulation of cellular metabolic process
1.48 1.58e-11 GO:0010604 positive regulation of macromolecule metabolic process
1.37 1.59e-11 GO:0048583 regulation of response to stimulus
1.24 2.17e-11 GO:0023052 signaling
1.59 2.20e-11 GO:0046907 intracellular transport
1.83 2.57e-11 GO:0016032 viral reproduction
1.62 5.27e-11 GO:0002682 regulation of immune system process
2.07 6.63e-11 GO:0045321 leukocyte activation
1.44 1.16e-10 GO:0051641 cellular localization
1.72 1.21e-10 GO:0006974 response to DNA damage stimulus
1.55 1.46e-10 GO:0043933 macromolecular complex subunit organization
1.72 1.83e-10 GO:0001775 cell activation
1.44 1.95e-10 GO:0009893 positive regulation of metabolic process
1.82 3.10e-09 GO:0010564 regulation of cell cycle process
1.50 4.20e-09 GO:0051704 multi-organism process
1.28 4.97e-09 GO:0010468 regulation of gene expression
1.44 6.96e-09 GO:0051649 establishment of localization in cell
1.27 9.83e-09 GO:0031326 regulation of cellular biosynthetic process
1.61 1.04e-08 GO:0071822 protein complex subunit organization
1.26 1.57e-08 GO:0009889 regulation of biosynthetic process
1.26 2.01e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.37 2.25e-08 GO:0065009 regulation of molecular function
1.27 2.47e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.45 3.07e-08 GO:0007049 cell cycle
1.65 4.06e-08 GO:0007599 hemostasis
1.48 4.41e-08 GO:0006351 transcription, DNA-dependent
1.65 4.62e-08 GO:0007596 blood coagulation
1.65 4.62e-08 GO:0050817 coagulation
1.58 5.97e-08 GO:0051276 chromosome organization
1.45 6.46e-08 GO:0009892 negative regulation of metabolic process
1.54 6.88e-08 GO:0019220 regulation of phosphate metabolic process
1.54 6.88e-08 GO:0051174 regulation of phosphorus metabolic process
1.67 8.55e-08 GO:0050776 regulation of immune response
1.40 1.14e-07 GO:0044248 cellular catabolic process
1.27 1.24e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.43 1.66e-07 GO:0006793 phosphorus metabolic process
1.43 1.66e-07 GO:0006796 phosphate metabolic process
1.58 1.95e-07 GO:0050878 regulation of body fluid levels
2.06 2.24e-07 GO:0002757 immune response-activating signal transduction
1.82 2.60e-07 GO:0006366 transcription from RNA polymerase II promoter
1.46 2.99e-07 GO:0008219 cell death
1.73 3.54e-07 GO:0016568 chromatin modification
1.62 3.82e-07 GO:0034621 cellular macromolecular complex subunit organization
1.56 4.56e-07 GO:0006259 DNA metabolic process
1.36 4.80e-07 GO:0035556 intracellular signal transduction
1.52 5.08e-07 GO:0042325 regulation of phosphorylation
1.45 5.18e-07 GO:0016265 death
1.51 6.84e-07 GO:0065003 macromolecular complex assembly
1.64 7.01e-07 GO:0002684 positive regulation of immune system process
1.65 7.47e-07 GO:0043069 negative regulation of programmed cell death
2.01 8.29e-07 GO:0002764 immune response-regulating signaling pathway
1.98 8.86e-07 GO:0046649 lymphocyte activation
1.69 9.61e-07 GO:0032270 positive regulation of cellular protein metabolic process
2.16 1.38e-06 GO:0019058 viral infectious cycle
1.64 1.42e-06 GO:0043066 negative regulation of apoptosis
1.98 1.43e-06 GO:0022411 cellular component disassembly
1.98 1.43e-06 GO:0071845 cellular component disassembly at cellular level
1.48 1.50e-06 GO:0016192 vesicle-mediated transport
1.43 1.54e-06 GO:0031324 negative regulation of cellular metabolic process
1.66 1.60e-06 GO:0051247 positive regulation of protein metabolic process
1.73 1.68e-06 GO:0070647 protein modification by small protein conjugation or removal
1.34 1.73e-06 GO:0009056 catabolic process
1.43 1.76e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.26 1.94e-06 GO:0051252 regulation of RNA metabolic process
1.61 2.26e-06 GO:0006325 chromatin organization
1.37 2.36e-06 GO:0050790 regulation of catalytic activity
1.23 2.44e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 2.58e-06 GO:0071156 regulation of cell cycle arrest
1.59 3.30e-06 GO:0043549 regulation of kinase activity
1.33 3.51e-06 GO:0009966 regulation of signal transduction
2.25 3.69e-06 GO:0051320 S phase
1.51 3.75e-06 GO:0001932 regulation of protein phosphorylation
1.44 4.03e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.35 4.28e-06 GO:0010033 response to organic substance
1.71 5.13e-06 GO:0051603 proteolysis involved in cellular protein catabolic process
2.09 5.55e-06 GO:0000082 G1/S transition of mitotic cell cycle
2.24 5.61e-06 GO:0000084 S phase of mitotic cell cycle
1.60 7.09e-06 GO:0060548 negative regulation of cell death
1.47 7.24e-06 GO:0012501 programmed cell death
1.52 8.40e-06 GO:0042060 wound healing
1.69 8.54e-06 GO:0044257 cellular protein catabolic process
1.43 1.11e-05 GO:0044093 positive regulation of molecular function
2.01 1.13e-05 GO:0022415 viral reproductive process
1.86 1.16e-05 GO:0000075 cell cycle checkpoint
1.55 1.23e-05 GO:0043068 positive regulation of programmed cell death
1.43 1.24e-05 GO:0048584 positive regulation of response to stimulus
1.42 1.29e-05 GO:0009891 positive regulation of biosynthetic process
1.55 1.40e-05 GO:0043065 positive regulation of apoptosis
1.46 1.58e-05 GO:0006915 apoptosis
1.39 1.78e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.35 1.93e-05 GO:0044085 cellular component biogenesis
2.30 1.99e-05 GO:0050851 antigen receptor-mediated signaling pathway
1.74 2.38e-05 GO:0010608 posttranscriptional regulation of gene expression
1.54 2.61e-05 GO:0051338 regulation of transferase activity
1.29 3.03e-05 GO:0023051 regulation of signaling
1.41 3.06e-05 GO:0016310 phosphorylation
1.37 3.17e-05 GO:0022607 cellular component assembly
1.64 3.79e-05 GO:0030163 protein catabolic process
1.40 3.84e-05 GO:0009611 response to wounding
1.67 4.16e-05 GO:0019941 modification-dependent protein catabolic process
1.53 4.49e-05 GO:0010942 positive regulation of cell death
1.24 4.49e-05 GO:0042221 response to chemical stimulus
1.27 4.50e-05 GO:0007166 cell surface receptor linked signaling pathway
1.69 4.57e-05 GO:0006412 translation
1.55 4.95e-05 GO:0045859 regulation of protein kinase activity
1.67 5.10e-05 GO:0051098 regulation of binding
1.38 5.78e-05 GO:0042127 regulation of cell proliferation
1.69 5.88e-05 GO:0051329 interphase of mitotic cell cycle
1.70 6.12e-05 GO:0002520 immune system development
1.66 6.23e-05 GO:0043632 modification-dependent macromolecule catabolic process
1.73 6.72e-05 GO:0007346 regulation of mitotic cell cycle
1.64 6.75e-05 GO:0006281 DNA repair
1.70 6.93e-05 GO:0050778 positive regulation of immune response
1.41 7.21e-05 GO:0022402 cell cycle process
1.68 7.84e-05 GO:0051325 interphase
1.71 8.13e-05 GO:0032446 protein modification by small protein conjugation
1.42 9.17e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.51 1.08e-04 GO:0080134 regulation of response to stress
1.66 1.11e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.79 1.13e-04 GO:0002253 activation of immune response
1.61 1.16e-04 GO:0045087 innate immune response
1.42 1.31e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.79 1.43e-04 GO:0051249 regulation of lymphocyte activation
2.16 1.45e-04 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.31 1.49e-04 GO:0033036 macromolecule localization
2.18 1.51e-04 GO:0006414 translational elongation
2.20 1.55e-04 GO:0030098 lymphocyte differentiation
1.23 1.68e-04 GO:0065008 regulation of biological quality
1.56 1.84e-04 GO:0007243 intracellular protein kinase cascade
1.56 1.84e-04 GO:0023014 signal transduction via phosphorylation event
1.40 1.89e-04 GO:0006952 defense response
1.52 1.95e-04 GO:0070271 protein complex biogenesis
1.88 2.16e-04 GO:0051251 positive regulation of lymphocyte activation
1.52 2.22e-04 GO:0006461 protein complex assembly
1.86 2.30e-04 GO:0016569 covalent chromatin modification
1.61 2.52e-04 GO:0006917 induction of apoptosis
1.44 2.87e-04 GO:0071310 cellular response to organic substance
1.90 2.94e-04 GO:0031400 negative regulation of protein modification process
1.34 3.02e-04 GO:0010646 regulation of cell communication
1.60 3.03e-04 GO:0012502 induction of programmed cell death
1.83 3.11e-04 GO:0050867 positive regulation of cell activation
1.67 3.25e-04 GO:0071900 regulation of protein serine/threonine kinase activity
1.65 3.35e-04 GO:0031401 positive regulation of protein modification process
1.40 3.50e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.75 3.85e-04 GO:0002274 myeloid leukocyte activation
1.68 3.86e-04 GO:0048534 hemopoietic or lymphoid organ development
1.49 3.98e-04 GO:0070727 cellular macromolecule localization
1.70 4.74e-04 GO:0050865 regulation of cell activation
1.37 5.14e-04 GO:0015031 protein transport
1.72 5.55e-04 GO:0030097 hemopoiesis
2.08 6.14e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.84 6.27e-04 GO:0016570 histone modification
1.46 6.34e-04 GO:0000278 mitotic cell cycle
1.71 6.89e-04 GO:0032269 negative regulation of cellular protein metabolic process
1.48 7.91e-04 GO:0034613 cellular protein localization
1.81 8.32e-04 GO:0002696 positive regulation of leukocyte activation
1.61 8.50e-04 GO:0033043 regulation of organelle organization
2.06 8.64e-04 GO:0000077 DNA damage checkpoint
1.22 1.00e-03 GO:0006355 regulation of transcription, DNA-dependent
1.40 1.17e-03 GO:0043085 positive regulation of catalytic activity
2.04 1.21e-03 GO:0032984 macromolecular complex disassembly
2.04 1.21e-03 GO:0034623 cellular macromolecular complex disassembly
1.32 1.22e-03 GO:0008104 protein localization
1.85 1.41e-03 GO:0010498 proteasomal protein catabolic process
1.85 1.41e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.69 1.48e-03 GO:0002694 regulation of leukocyte activation
1.96 1.50e-03 GO:0002521 leukocyte differentiation
1.35 1.51e-03 GO:0045184 establishment of protein localization
1.54 1.58e-03 GO:0006886 intracellular protein transport
1.84 1.64e-03 GO:0006417 regulation of translation
1.66 1.64e-03 GO:0016567 protein ubiquitination
1.86 1.75e-03 GO:0050900 leukocyte migration
2.18 1.88e-03 GO:0019080 viral genome expression
2.18 1.88e-03 GO:0019083 viral transcription
1.65 1.89e-03 GO:0051101 regulation of DNA binding
1.38 2.06e-03 GO:0006468 protein phosphorylation
1.80 2.16e-03 GO:0050863 regulation of T cell activation
1.66 2.59e-03 GO:0051248 negative regulation of protein metabolic process
1.39 2.71e-03 GO:0022403 cell cycle phase
1.53 2.80e-03 GO:0010627 regulation of intracellular protein kinase cascade
1.98 2.90e-03 GO:0031570 DNA integrity checkpoint
2.19 2.95e-03 GO:0000216 M/G1 transition of mitotic cell cycle
2.38 2.97e-03 GO:0006368 transcription elongation from RNA polymerase II promoter
2.22 3.02e-03 GO:0050852 T cell receptor signaling pathway
2.00 3.44e-03 GO:0006401 RNA catabolic process
2.00 3.44e-03 GO:0042770 signal transduction in response to DNA damage
1.71 3.68e-03 GO:0006916 anti-apoptosis
1.96 3.94e-03 GO:0042110 T cell activation
1.33 4.46e-03 GO:0070887 cellular response to chemical stimulus
1.16 4.46e-03 GO:0051179 localization
1.77 4.46e-03 GO:0045088 regulation of innate immune response
2.05 4.66e-03 GO:0043241 protein complex disassembly
2.05 4.66e-03 GO:0043624 cellular protein complex disassembly
1.87 5.09e-03 GO:0006310 DNA recombination
1.56 5.09e-03 GO:0031347 regulation of defense response
2.10 5.64e-03 GO:0006415 translational termination
1.44 6.81e-03 GO:0044092 negative regulation of molecular function
1.52 6.88e-03 GO:0034622 cellular macromolecular complex assembly
1.47 8.66e-03 GO:0008283 cell proliferation
1.54 8.67e-03 GO:0045597 positive regulation of cell differentiation
1.38 8.73e-03 GO:0051254 positive regulation of RNA metabolic process
2.48 9.58e-03 GO:0002263 cell activation involved in immune response
2.48 9.58e-03 GO:0002366 leukocyte activation involved in immune response
1.84 9.63e-03 GO:0050870 positive regulation of T cell activation
2.02 9.68e-03 GO:0051340 regulation of ligase activity
1.82 9.96e-03 GO:0031396 regulation of protein ubiquitination
2.18 1.03e-02 GO:0042113 B cell activation
1.46 1.13e-02 GO:0016044 cellular membrane organization
1.99 1.23e-02 GO:0040029 regulation of gene expression, epigenetic
1.95 1.39e-02 GO:0090068 positive regulation of cell cycle process
2.13 1.43e-02 GO:0006354 transcription elongation, DNA-dependent
1.45 1.48e-02 GO:0061024 membrane organization
1.44 1.56e-02 GO:0009628 response to abiotic stimulus
1.88 1.65e-02 GO:0043388 positive regulation of DNA binding
2.23 1.66e-02 GO:0071158 positive regulation of cell cycle arrest
1.85 1.74e-02 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
1.58 1.86e-02 GO:0001817 regulation of cytokine production
2.10 2.05e-02 GO:0000956 nuclear-transcribed mRNA catabolic process
2.55 2.05e-02 GO:0006283 transcription-coupled nucleotide-excision repair
2.01 2.16e-02 GO:0051438 regulation of ubiquitin-protein ligase activity
2.22 2.53e-02 GO:0048524 positive regulation of viral reproduction
1.79 2.64e-02 GO:0051099 positive regulation of binding
1.88 2.68e-02 GO:0007265 Ras protein signal transduction
2.05 2.70e-02 GO:0022618 ribonucleoprotein complex assembly
1.44 2.82e-02 GO:0051094 positive regulation of developmental process
1.66 2.96e-02 GO:0043405 regulation of MAP kinase activity
1.41 2.99e-02 GO:0009967 positive regulation of signal transduction
1.89 3.30e-02 GO:0051028 mRNA transport
1.35 3.48e-02 GO:0009890 negative regulation of biosynthetic process
2.03 3.77e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
1.51 3.82e-02 GO:0032535 regulation of cellular component size
1.69 4.22e-02 GO:0051169 nuclear transport
2.06 4.35e-02 GO:0008063 Toll signaling pathway
1.28 4.40e-02 GO:0009605 response to external stimulus
1.37 4.55e-02 GO:0010629 negative regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 4.09e-64 GO:0044424 intracellular part
1.18 1.33e-58 GO:0005622 intracellular
1.67 7.44e-52 GO:0044428 nuclear part
1.61 2.84e-46 GO:0031974 membrane-enclosed lumen
1.70 5.30e-46 GO:0031981 nuclear lumen
1.24 8.66e-46 GO:0005737 cytoplasm
1.23 2.14e-45 GO:0043227 membrane-bounded organelle
1.22 3.98e-45 GO:0043231 intracellular membrane-bounded organelle
1.60 5.38e-45 GO:0043233 organelle lumen
1.60 1.14e-43 GO:0070013 intracellular organelle lumen
1.19 1.70e-42 GO:0043229 intracellular organelle
1.19 1.98e-42 GO:0043226 organelle
1.33 4.19e-42 GO:0005634 nucleus
1.33 5.94e-42 GO:0044446 intracellular organelle part
1.32 5.64e-41 GO:0044422 organelle part
1.42 9.35e-37 GO:0032991 macromolecular complex
1.75 1.24e-36 GO:0005654 nucleoplasm
1.56 1.86e-34 GO:0005829 cytosol
1.25 3.97e-28 GO:0044444 cytoplasmic part
1.36 3.49e-22 GO:0043234 protein complex
1.87 1.09e-17 GO:0030529 ribonucleoprotein complex
1.69 5.27e-16 GO:0044451 nucleoplasm part
1.06 7.52e-16 GO:0044464 cell part
1.06 8.28e-16 GO:0005623 cell
1.31 1.27e-14 GO:0043228 non-membrane-bounded organelle
1.31 1.27e-14 GO:0043232 intracellular non-membrane-bounded organelle
1.65 1.33e-10 GO:0005694 chromosome
1.98 3.48e-09 GO:0016604 nuclear body
1.62 1.31e-08 GO:0005730 nucleolus
1.62 7.11e-08 GO:0044427 chromosomal part
2.09 1.34e-06 GO:0005681 spliceosomal complex
1.77 4.44e-05 GO:0000228 nuclear chromosome
1.41 5.32e-05 GO:0031967 organelle envelope
2.55 6.25e-05 GO:0016605 PML body
1.85 6.58e-05 GO:0044454 nuclear chromosome part
1.72 7.44e-05 GO:0000785 chromatin
1.22 8.97e-05 GO:0031090 organelle membrane
1.39 1.38e-04 GO:0031975 envelope
1.68 2.14e-04 GO:0005635 nuclear envelope
1.85 3.10e-04 GO:0044445 cytosolic part
2.17 6.55e-04 GO:0071013 catalytic step 2 spliceosome
1.90 1.30e-03 GO:0016607 nuclear speck
1.94 1.92e-03 GO:0030055 cell-substrate junction
3.43 3.15e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.99 4.48e-03 GO:0016585 chromatin remodeling complex
1.43 5.03e-03 GO:0005768 endosome
1.67 5.38e-03 GO:0005840 ribosome
1.22 6.02e-03 GO:0012505 endomembrane system
1.98 6.66e-03 GO:0042470 melanosome
1.98 6.66e-03 GO:0048770 pigment granule
2.06 9.92e-03 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.06 9.92e-03 GO:0022626 cytosolic ribosome
1.87 1.07e-02 GO:0005924 cell-substrate adherens junction
4.75 1.24e-02 GO:0005885 Arp2/3 protein complex
1.97 1.60e-02 GO:0000790 nuclear chromatin
1.87 1.74e-02 GO:0005925 focal adhesion
1.72 1.81e-02 GO:0031965 nuclear membrane
1.78 1.89e-02 GO:0044455 mitochondrial membrane part
2.52 2.90e-02 GO:0042645 mitochondrial nucleoid
2.03 3.35e-02 GO:0034399 nuclear periphery
1.51 3.67e-02 GO:0044440 endosomal part
2.62 3.98e-02 GO:0008305 integrin complex
2.15 4.63e-02 GO:0034708 methyltransferase complex
2.15 4.63e-02 GO:0035097 histone methyltransferase complex
2.44 4.79e-02 GO:0009295 nucleoid
1.50 4.85e-02 GO:0010008 endosome membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.40 6.11e-101 GO:0005515 protein binding
1.16 2.20e-52 GO:0005488 binding
1.70 3.86e-19 GO:0003723 RNA binding
1.31 9.15e-12 GO:0000166 nucleotide binding
1.57 4.19e-11 GO:0019899 enzyme binding
1.78 3.93e-10 GO:0000988 protein binding transcription factor activity
1.78 3.93e-10 GO:0000989 transcription factor binding transcription factor activity
1.78 7.15e-10 GO:0003712 transcription cofactor activity
1.21 4.59e-08 GO:0003676 nucleic acid binding
1.28 1.13e-06 GO:0035639 purine ribonucleoside triphosphate binding
2.07 1.35e-06 GO:0003714 transcription corepressor activity
1.30 3.10e-06 GO:0005524 ATP binding
1.26 4.39e-06 GO:0032553 ribonucleotide binding
1.26 4.39e-06 GO:0032555 purine ribonucleotide binding
1.75 4.61e-06 GO:0032403 protein complex binding
1.26 4.94e-06 GO:0017076 purine nucleotide binding
1.29 7.24e-06 GO:0032559 adenyl ribonucleotide binding
1.29 1.01e-05 GO:0030554 adenyl nucleotide binding
2.97 2.05e-05 GO:0003823 antigen binding
1.41 5.25e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.38 1.17e-04 GO:0016301 kinase activity
1.35 1.64e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.12 3.45e-04 GO:0003824 catalytic activity
1.77 3.75e-04 GO:0043566 structure-specific DNA binding
1.42 4.61e-04 GO:0004672 protein kinase activity
1.69 8.26e-04 GO:0003713 transcription coactivator activity
1.66 9.16e-04 GO:0019900 kinase binding
1.37 2.35e-03 GO:0046983 protein dimerization activity
2.11 2.47e-03 GO:0008135 translation factor activity, nucleic acid binding
2.34 3.00e-03 GO:0003697 single-stranded DNA binding
2.26 3.03e-03 GO:0008094 DNA-dependent ATPase activity
1.45 3.66e-03 GO:0019904 protein domain specific binding
2.11 3.73e-03 GO:0031625 ubiquitin protein ligase binding
2.15 4.12e-03 GO:0047485 protein N-terminus binding
4.75 4.73e-03 GO:0019864 IgG binding
1.55 4.99e-03 GO:0008134 transcription factor binding
1.21 6.37e-03 GO:0016740 transferase activity
1.33 8.39e-03 GO:0042802 identical protein binding
2.38 1.05e-02 GO:0003743 translation initiation factor activity
1.71 1.25e-02 GO:0004721 phosphoprotein phosphatase activity
1.77 1.32e-02 GO:0004386 helicase activity
1.27 1.32e-02 GO:0030528 transcription regulator activity
2.50 1.45e-02 GO:0003678 DNA helicase activity
1.56 1.56e-02 GO:0016791 phosphatase activity
2.06 1.80e-02 GO:0042393 histone binding
1.71 2.56e-02 GO:0003735 structural constituent of ribosome
1.61 2.56e-02 GO:0019901 protein kinase binding
1.61 4.30e-02 GO:0003682 chromatin binding
1.98 4.72e-02 GO:0003729 mRNA binding