Motif ID: SPZ1.p2

Z-value: 1.277


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1



Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_60337350 28.837 NM_021136
 RTN1
reticulon 1
chrX_-_13956530 28.249 GPM6B
glycoprotein M6B
chrX_-_13956644 24.229 NM_001001994
 GPM6B
glycoprotein M6B
chrX_-_13956445 22.940


chr20_+_44657858 13.145 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr6_-_70506843 13.047 NM_018368
 LMBRD1
LMBR1 domain containing 1
chr6_-_70506524 12.990 LMBRD1
LMBR1 domain containing 1
chr1_-_182360400 12.942 NM_001033056
 GLUL
glutamate-ammonia ligase
chr6_-_70506768 12.531 LMBRD1
LMBR1 domain containing 1
chr6_-_84418705 12.317 NM_001242792
 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr12_+_79258448 12.052 NM_005639
 SYT1
synaptotagmin I
chr17_-_37764165 11.737 NM_006160
 NEUROD2
neurogenic differentiation 2
chr12_+_79258588 11.434 SYT1
synaptotagmin I
chr8_-_22089850 11.118 NM_001099335
NM_014759
 PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr19_-_36523770 11.054 NM_015526
 CLIP3
CAP-GLY domain containing linker protein 3
chr16_+_2039945 10.983 NM_004209
 SYNGR3
synaptogyrin 3
chr6_+_107811272 10.968 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chr13_+_42031525 10.658 NM_014059
 C13orf15
chromosome 13 open reading frame 15
chr12_+_79258517 10.616 SYT1
synaptotagmin I
chr22_-_44258210 10.411 NM_014351
 SULT4A1
sulfotransferase family 4A, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 144 entries
enrichment   p-value GO term description
2.35 2.23e-02 GO:0007269 neurotransmitter secretion
2.20 7.74e-04 GO:0006836 neurotransmitter transport
2.07 4.23e-02 GO:0021537 telencephalon development
1.89 1.79e-03 GO:0030900 forebrain development
1.84 9.67e-14 GO:0048666 neuron development
1.82 7.65e-07 GO:0007411 axon guidance
1.81 1.86e-09 GO:0048812 neuron projection morphogenesis
1.81 2.29e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.80 1.22e-10 GO:0000904 cell morphogenesis involved in differentiation
1.79 1.81e-08 GO:0007409 axonogenesis
1.79 8.47e-04 GO:0051129 negative regulation of cellular component organization
1.78 8.36e-15 GO:0030182 neuron differentiation
1.78 1.00e-02 GO:0048732 gland development
1.77 1.14e-09 GO:0019226 transmission of nerve impulse
1.77 1.14e-09 GO:0035637 multicellular organismal signaling
1.77 2.61e-08 GO:0007268 synaptic transmission
1.73 2.59e-02 GO:0045664 regulation of neuron differentiation
1.72 5.27e-16 GO:0048699 generation of neurons
1.72 7.13e-03 GO:0030168 platelet activation
1.71 5.87e-10 GO:0000902 cell morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
2.14 4.40e-02 GO:0030426 growth cone
2.09 2.03e-02 GO:0033267 axon part
2.07 1.38e-02 GO:0030139 endocytic vesicle
2.05 7.19e-07 GO:0030424 axon
1.83 3.12e-10 GO:0043005 neuron projection
1.80 2.04e-02 GO:0043235 receptor complex
1.77 3.81e-03 GO:0043025 neuronal cell body
1.72 9.83e-03 GO:0044297 cell body
1.66 2.22e-02 GO:0030425 dendrite
1.61 2.76e-05 GO:0045202 synapse
1.54 1.36e-02 GO:0044456 synapse part
1.51 1.07e-08 GO:0042995 cell projection
1.47 2.61e-02 GO:0048471 perinuclear region of cytoplasm
1.46 1.51e-10 GO:0005887 integral to plasma membrane
1.45 1.37e-10 GO:0031226 intrinsic to plasma membrane
1.44 7.56e-06 GO:0031982 vesicle
1.44 3.75e-05 GO:0031988 membrane-bounded vesicle
1.43 3.00e-05 GO:0031410 cytoplasmic vesicle
1.43 6.67e-05 GO:0016023 cytoplasmic membrane-bounded vesicle
1.42 1.59e-03 GO:0030054 cell junction

Gene overrepresentation in function category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
4.87 9.95e-03 GO:0070742 C2H2 zinc finger domain binding
3.76 1.41e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.97 5.82e-04 GO:0005516 calmodulin binding
1.67 1.12e-04 GO:0016563 transcription activator activity
1.56 1.70e-02 GO:0005083 small GTPase regulator activity
1.56 3.50e-02 GO:0005261 cation channel activity
1.52 9.31e-07 GO:0043565 sequence-specific DNA binding
1.51 4.46e-02 GO:0022836 gated channel activity
1.50 1.46e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.47 1.70e-08 GO:0001071 nucleic acid binding transcription factor activity
1.47 1.70e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.47 1.49e-04 GO:0004672 protein kinase activity
1.46 5.13e-06 GO:0016301 kinase activity
1.46 1.06e-02 GO:0004674 protein serine/threonine kinase activity
1.45 2.69e-02 GO:0022803 passive transmembrane transporter activity
1.44 2.05e-03 GO:0008324 cation transmembrane transporter activity
1.44 4.12e-03 GO:0008092 cytoskeletal protein binding
1.44 4.00e-02 GO:0015267 channel activity
1.43 2.28e-02 GO:0030695 GTPase regulator activity
1.42 3.07e-02 GO:0060589 nucleoside-triphosphatase regulator activity