Motif ID: T.p2

Z-value: 0.778


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Tchr6_-_166582129-0.143.9e-02Click!


Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_25958245 20.082 LGALS9
lectin, galactoside-binding, soluble, 9
chr14_-_107013474 17.535 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_25958257 15.020 LGALS9
lectin, galactoside-binding, soluble, 9
chr9_-_75568232 12.275 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr17_+_25958217 12.255 LGALS9
lectin, galactoside-binding, soluble, 9
chrX_+_128913881 11.291 NM_018990
SASH3
SAM and SH3 domain containing 3
chr17_+_25958192 11.107 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 10.821 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr9_-_75567915 10.428 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_+_174844655 10.329 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chrX_+_128913897 9.615 SASH3
SAM and SH3 domain containing 3
chr2_-_152146373 8.402 NM_004688
NMI
N-myc (and STAT) interactor
chr3_-_18480203 6.266 NM_001131010
SATB1
SATB homeobox 1
chr12_+_69742140 6.190 LYZ
lysozyme
chr17_+_34431219 5.506 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr11_+_117947785 5.379 TMPRSS4
transmembrane protease, serine 4
chr16_+_77233348 5.307 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr14_-_107113943 5.223 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_117947726 5.088 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr4_-_74847669 4.921 NM_002619
PF4
platelet factor 4
chr12_+_69742130 4.587 NM_000239
LYZ
lysozyme
chr11_-_111249902 4.528 POU2AF1
POU class 2 associating factor 1
chr5_-_39270708 4.237 NM_001243093
FYB
FYN binding protein
chr12_-_53074172 4.013 NM_006121
KRT1
keratin 1
chr10_+_5136589 4.008 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr5_+_54320083 3.446 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr16_-_67965754 3.221 NM_001907
CTRL
chymotrypsin-like
chr10_+_5136556 3.221 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_+_7461591 3.213 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr10_+_70847857 3.092 SRGN
serglycin
chr14_-_106994001 3.049 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr10_+_70847817 3.032 NM_002727
SRGN
serglycin
chr2_-_100722328 2.785 AFF3
AF4/FMR2 family, member 3
chr8_+_103563847 2.781 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr1_+_16062808 2.778 NM_207348
SLC25A34
solute carrier family 25, member 34
chr1_+_209941894 2.760 TRAF3IP3
TRAF3 interacting protein 3
chr1_+_174843523 2.747 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr16_+_25228282 2.733 NM_001169
AQP8
aquaporin 8
chr4_-_151936648 2.730 NM_006726
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr2_+_103089761 2.697 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr14_+_95078713 2.692 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr13_-_20346398 2.663 PSPC1
paraspeckle component 1
chr10_-_98945379 2.603 SLIT1
slit homolog 1 (Drosophila)
chrX_+_37639306 2.533 CYBB
cytochrome b-245, beta polypeptide
chr5_+_96212167 2.395 ERAP2
endoplasmic reticulum aminopeptidase 2
chr3_-_119582422 2.387 GSK3B
glycogen synthase kinase 3 beta
chr16_+_69220940 2.358 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr17_-_79881304 2.318 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr17_+_34538464 2.226 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr11_-_59950498 2.207 NM_022349
NM_152851
MS4A6A

membrane-spanning 4-domains, subfamily A, member 6A

chr10_+_5136613 2.171 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr5_+_96211643 2.158 NM_001130140
NM_022350
ERAP2

endoplasmic reticulum aminopeptidase 2

chr10_+_111765725 2.134 NM_019903
ADD3
adducin 3 (gamma)
chr14_-_106692107 2.107 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_107078578 2.107


chr22_-_51016343 2.073 NM_001145137
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr7_+_143013218 2.053 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr22_+_22676814 1.956


chr14_-_106725620 1.908 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr6_+_32132379 1.872 NM_030652
EGFL8
EGF-like-domain, multiple 8
chr7_-_36764000 1.845 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr6_-_74229094 1.824 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr6_+_109762204 1.819 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr6_+_49467670 1.817 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr12_-_52845862 1.709 NM_005555
KRT6B
keratin 6B
chr5_-_138725544 1.675 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr7_-_16505292 1.668 NM_015464
SOSTDC1
sclerostin domain containing 1
chr16_+_67596309 1.646 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr5_-_39203061 1.617 FYB
FYN binding protein
chr12_+_96252770 1.596 SNRPF
small nuclear ribonucleoprotein polypeptide F
chr1_+_27114409 1.595 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr10_+_118305427 1.538 NM_000936
PNLIP
pancreatic lipase
chr19_-_45681454 1.529 NM_024108
TRAPPC6A
trafficking protein particle complex 6A
chr10_-_23003443 1.517 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr12_+_96252705 1.489 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr15_+_91447419 1.487 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr7_+_99816870 1.486 NM_024070
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr6_+_167536240 1.467 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr6_-_31681845 1.464


chr1_+_114472438 1.460 HIPK1
homeodomain interacting protein kinase 1
chr16_-_88717395 1.447 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr6_-_32634287 1.420 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr1_-_20306093 1.411 NM_001161729
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr12_-_52867521 1.364 NM_173086
KRT6C
keratin 6C
chr16_+_57653649 1.316 GPR56
G protein-coupled receptor 56
chr9_+_75766777 1.315 NM_000700
ANXA1
annexin A1
chr20_+_1093905 1.311 NM_178578
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr17_-_19648924 1.282 NM_001135167
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chrX_+_70443055 1.280 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr11_-_120008848 1.272 NM_012101
TRIM29
tripartite motif containing 29
chr19_-_11688508 1.266 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr12_-_91576579 1.203 DCN
decorin
chr17_+_7462064 1.170 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr7_-_87849341 1.168 SRI
sorcin
chr14_-_106691698 1.164


chr4_+_160188997 1.163 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr11_-_120008801 1.147 TRIM29
tripartite motif containing 29
chr9_+_75766794 1.142 ANXA1
annexin A1
chr1_-_153029987 1.134 NM_005988
SPRR2A
small proline-rich protein 2A
chr19_-_11688441 1.123 ACP5
acid phosphatase 5, tartrate resistant
chr1_+_26737232 1.076 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr8_-_42234562 1.075 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr12_+_21525801 1.062 NM_000415
IAPP
islet amyloid polypeptide
chr11_-_33913835 1.031 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr6_-_6320875 1.005 F13A1
coagulation factor XIII, A1 polypeptide
chr19_-_55767103 1.003 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr3_+_137728949 1.001 NM_016369
CLDN18
claudin 18
chr1_-_114414245 0.980 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr4_-_16077740 0.969 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr4_-_145061787 0.968 NM_002099
GYPA
glycophorin A (MNS blood group)
chr20_+_35973083 0.968 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr15_+_60296506 0.964 FOXB1
forkhead box B1
chr22_+_40441371 0.962 TNRC6B
trinucleotide repeat containing 6B
chr3_+_133502876 0.951 NM_021203
SRPRB
signal recognition particle receptor, B subunit
chr1_-_27953046 0.948 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr16_+_53468373 0.946 RBL2
retinoblastoma-like 2 (p130)
chr12_-_52779362 0.939 NM_033045
KRT84
keratin 84
chr15_+_60296420 0.891 NM_012182
FOXB1
forkhead box B1
chr11_-_120008738 0.872 TRIM29
tripartite motif containing 29
chr6_-_49754899 0.854 NM_138733
PGK2
phosphoglycerate kinase 2
chr9_-_37034358 0.849 NM_016734
PAX5
paired box 5
chr10_+_11047253 0.830 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr14_-_106725232 0.814 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr11_+_34073188 0.809 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr11_-_124806302 0.795 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr4_+_128651518 0.795 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr14_-_107218786 0.790 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr4_-_144940439 0.786 NM_002100
GYPB
glycophorin B (MNS blood group)
chr7_+_100027404 0.770 MEPCE
methylphosphate capping enzyme
chr11_+_60223281 0.768 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr17_+_57970442 0.745 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr6_-_6320897 0.743 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr20_-_52199635 0.740 NM_006526
ZNF217
zinc finger protein 217
chr3_+_25469749 0.733 NM_016152
RARB
retinoic acid receptor, beta
chr17_-_61996135 0.727 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chrX_+_16804531 0.720 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr15_-_40600025 0.720 PLCB2
phospholipase C, beta 2
chr2_-_237172987 0.703 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr10_+_114133838 0.687 NM_203379
ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_31620142 0.681 NM_001098534
BAG6
BCL2-associated athanogene 6
chr1_-_153067000 0.681 NM_001024209
SPRR2E
small proline-rich protein 2E
chr15_-_80263460 0.662 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr7_+_100027253 0.654 NM_019606
MEPCE
methylphosphate capping enzyme
chr1_-_12677347 0.625 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr2_+_234601511 0.623 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr16_+_85645014 0.617 NM_001134473
KIAA0182
KIAA0182
chr1_+_38022514 0.617 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr10_+_49514652 0.616 MAPK8
mitogen-activated protein kinase 8
chr5_+_139876504 0.604 ANKHD1
ankyrin repeat and KH domain containing 1
chr6_-_29012951 0.590 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr1_+_55007927 0.588 ACOT11
acyl-CoA thioesterase 11
chr3_+_38307297 0.584 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr17_-_61973870 0.579 NM_001317
CSH1
chorionic somatomammotropin hormone 1 (placental lactogen)
chr9_+_33750463 0.568 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr3_+_101395299 0.566 LOC100009676
uncharacterized LOC100009676
chr17_+_40714091 0.561 NM_001042529
NM_001042530
NM_001042531
NM_001042532
NM_025233
COASY




CoA synthase




chr7_+_2282440 0.558 NM_198953
NM_198954
NUDT1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

chr16_+_12058963 0.556 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr7_+_117864711 0.555 NM_019644
ANKRD7
ankyrin repeat domain 7
chr1_-_204329043 0.551 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr3_-_58200397 0.550 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr2_+_219081864 0.541 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr17_+_34640030 0.534 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr1_-_12908141 0.534 NM_001146181
HNRNPCL1
LOC649330
heterogeneous nuclear ribonucleoprotein C-like 1
heterogeneous nuclear ribonucleoprotein C-like
chr4_+_124317884 0.528 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_+_56324945 0.526 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr1_+_156123321 0.518 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr1_+_26737306 0.511 LIN28A
lin-28 homolog A (C. elegans)
chr11_-_113577023 0.509 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr17_-_61988614 0.499 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr12_-_7125727 0.498 NM_005768
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr1_-_154842725 0.497 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr17_-_56296965 0.493 NM_001165927
MKS1
Meckel syndrome, type 1
chr10_-_76868853 0.483 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr2_-_219031646 0.479 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr12_-_8043743 0.476 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr17_+_40714176 0.476 COASY
CoA synthase
chr2_+_219246751 0.472 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr15_+_91411884 0.466 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr10_+_11060069 0.461 CELF2
CUGBP, Elav-like family member 2
chr6_-_90062349 0.455 UBE2J1
ubiquitin-conjugating enzyme E2, J1, U
chr18_-_3219846 0.450 MYOM1
myomesin 1, 185kDa
chr1_-_117210301 0.448 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr19_-_41255827 0.447 NM_198476
C19orf54
chromosome 19 open reading frame 54
chr6_-_31619481 0.445


chr9_+_135937364 0.444 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr17_-_10452939 0.435 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr19_+_55174123 0.426 NM_001081438
NM_006847
LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4

chr17_-_61959160 0.413 NM_002059
NM_022556
NM_022557
NM_022558
GH2



growth hormone 2



chr1_+_45266048 0.405 PLK3
polo-like kinase 3
chr19_+_55281262 0.399 NM_014218
KIR2DL1
KIR2DS4
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
chr4_-_144826659 0.395 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr2_-_61697899 0.394 USP34
ubiquitin specific peptidase 34
chr17_+_17942584 0.390 NM_024052
C17orf39
chromosome 17 open reading frame 39
chr16_-_30905451 0.389 BCL7C
B-cell CLL/lymphoma 7C
chr3_-_57678594 0.388 NM_152678
FAM116A
family with sequence similarity 116, member A
chr4_+_74719012 0.378 NM_002620
PF4V1
platelet factor 4 variant 1
chr1_+_39456887 0.376 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr5_-_172083569 0.375


chr17_-_61950997 0.370 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
12.75 4.01e-05 GO:0003823 antigen binding