Motif ID: TEAD1.p2

Z-value: 2.621


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD3chr6_-_354647160.622.0e-24Click!
TEAD1chr11_+_126958510.518.1e-16Click!
TEAD4chr12_+_30689890.019.3e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_90712510 114.932 NM_001613
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr6_-_132272311 108.515 NM_001901
 CTGF
connective tissue growth factor
chr5_-_39424930 61.068 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr20_+_35169876 60.486 NM_006097
NM_181526
 MYL9

myosin, light chain 9, regulatory

chr20_+_35169897 57.985 MYL9
myosin, light chain 9, regulatory
chr5_-_151066445 55.770 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_-_151066492 49.314 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr16_+_226678 46.493 NM_000558
 HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr2_-_217540722 45.776 IGFBP5
insulin-like growth factor binding protein 5
chr16_+_222845 45.303 NM_000517
 HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr5_-_39425030 44.064 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr12_-_7245006 42.268 NM_001733
 C1R
complement component 1, r subcomponent
chr12_-_7245048 41.904 C1R
complement component 1, r subcomponent
chr1_-_1293907 40.646 NM_032348
 MXRA8
matrix-remodelling associated 8
chr15_+_63334753 39.510 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
 TPM1





tropomyosin 1 (alpha)





chr19_+_45409003 38.095 NM_000041
 APOE
apolipoprotein E
chr1_-_12677347 37.446 NM_004753
 DHRS3
dehydrogenase/reductase (SDR family) member 3
chr22_+_21986968 37.079 NM_152612
 CCDC116
coiled-coil domain containing 116
chr15_+_63335086 35.987 TPM1
tropomyosin 1 (alpha)
chr11_+_114166534 34.727 NM_006169
 NNMT
nicotinamide N-methyltransferase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 66 entries
enrichment   p-value GO term description
6.40 1.29e-03 GO:0030049 muscle filament sliding
6.40 1.29e-03 GO:0033275 actin-myosin filament sliding
6.24 1.73e-03 GO:0070252 actin-mediated cell contraction
5.49 8.87e-04 GO:0030048 actin filament-based movement
3.90 3.04e-03 GO:0030198 extracellular matrix organization
3.14 2.54e-03 GO:0006936 muscle contraction
2.99 2.57e-02 GO:0043062 extracellular structure organization
2.88 1.11e-02 GO:0003012 muscle system process
2.85 2.11e-03 GO:0048514 blood vessel morphogenesis
2.76 7.03e-04 GO:0030334 regulation of cell migration
2.73 9.25e-04 GO:2000145 regulation of cell motility
2.72 2.63e-04 GO:0051270 regulation of cellular component movement
2.68 1.32e-03 GO:0001568 blood vessel development
2.67 8.39e-05 GO:0007411 axon guidance
2.57 2.23e-03 GO:0001944 vasculature development
2.57 2.23e-03 GO:0040012 regulation of locomotion
2.55 6.19e-06 GO:0048812 neuron projection morphogenesis
2.52 2.78e-05 GO:0007409 axonogenesis
2.50 2.56e-06 GO:0031175 neuron projection development
2.50 1.77e-02 GO:0008361 regulation of cell size

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
14.36 2.07e-02 GO:0001527 microfibril
14.36 2.07e-02 GO:0005587 collagen type IV
12.31 4.66e-02 GO:0030935 sheet-forming collagen
4.38 2.03e-03 GO:0016459 myosin complex
4.31 1.09e-03 GO:0005604 basement membrane
3.81 7.62e-05 GO:0044420 extracellular matrix part
2.98 1.77e-02 GO:0043292 contractile fiber
2.97 2.98e-02 GO:0030016 myofibril
2.51 1.42e-05 GO:0031012 extracellular matrix
2.49 4.76e-04 GO:0015629 actin cytoskeleton
2.32 2.08e-03 GO:0005578 proteinaceous extracellular matrix
2.07 1.39e-02 GO:0009986 cell surface
2.05 1.16e-08 GO:0044421 extracellular region part
1.91 1.15e-04 GO:0005615 extracellular space
1.71 6.71e-09 GO:0005576 extracellular region
1.53 1.88e-02 GO:0031226 intrinsic to plasma membrane
1.51 7.35e-05 GO:0044459 plasma membrane part
1.51 4.58e-02 GO:0005887 integral to plasma membrane
1.34 5.58e-05 GO:0071944 cell periphery
1.33 2.09e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
15.39 2.14e-03 GO:0003785 actin monomer binding
5.51 1.55e-03 GO:0008307 structural constituent of muscle
4.27 3.54e-06 GO:0008201 heparin binding
3.66 2.50e-06 GO:0001871 pattern binding
3.66 2.50e-06 GO:0030247 polysaccharide binding
3.66 8.96e-06 GO:0005539 glycosaminoglycan binding
3.50 3.91e-02 GO:0005201 extracellular matrix structural constituent
3.42 4.42e-03 GO:0019838 growth factor binding
2.30 8.97e-08 GO:0005509 calcium ion binding
2.20 1.43e-02 GO:0003779 actin binding
2.07 2.21e-02 GO:0030246 carbohydrate binding
1.60 2.98e-02 GO:0005102 receptor binding
1.19 6.25e-03 GO:0005515 protein binding